Best Enzyme Supplements for Heart Health of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Enzyme supplements are becoming increasingly popular for their potential benefits in supporting heart health. These supplements contain enzymes that help break down food and improve nutrient absorption, which can lead to improved circulation and cardiovascular function. Some enzymes, such as serrapeptase and nattokinase, are believed to have anti-inflammatory properties that may help reduce the risk of heart disease. While more research is needed to fully understand the benefits of enzyme supplements for heart health, many people are turning to these products as a natural way to support their cardiovascular system.

At a Glance: Our Top Picks

DEAL SUPPLEMENT Nattokinase 4,000 FU Cover #TOP 1
DEAL SUPPLEMENT Nattokinase 4,000 FU
ftb score rating icon 9.9
Nattokinase Supplement by Vimerson Health Cover #TOP 2
Nattokinase Supplement by Vimerson Health
ftb score rating icon 9.8
Doctor's Best Nattokinase Enzyme for Heart & Circulatory Health Cover #TOP 3
Doctor's Best Nattokinase Enzyme for Heart & Circulatory Health
ftb score rating icon 9.6

Top 8 Enzyme Supplements for Heart Health

#TOP 1

DEAL SUPPLEMENT Nattokinase 4,000 FU

BA-DS-NAT240
DEAL SUPPLEMENT Nattokinase 4,000 FU Cover
DEAL SUPPLEMENT Nattokinase 4,000 FU Per Serving, 240 Veggie Capsules – Bromelain, Turmeric Curcumin, with Black Pepper Complex – Heart Health & Digestive Enzymes – Non-GMO, Vegan

DEAL SUPPLEMENT Nattokinase offers a powerful blend of heart and digestive health support. Each serving contains 4,000 FU of Nattokinase along with Bromelain, Turmeric, and Black Pepper, enhancing nutrient absorption. This unique combination helps promote overall wellness for both men and women. With 240 veggie capsules, you can easily incorporate this supplement into your daily routine. The non-GMO, vegan formula ensures you are consuming high-quality ingredients free from common allergens, making it a safe choice for many users.

What We Like
Supports heart health
Enhances nutrient absorption
Non-GMO and vegan
240 veggie capsules
#TOP 2

Nattokinase Supplement by Vimerson Health

Nattokinase Supplement by Vimerson Health Cover
Nattokinase Supplement - Japanese Natto Superfood with High Potency Enzymes. Nattokinase 4000 FU. Balanced Circulation Supplements for Heart Health. 60 Nattokinase Powder Capsules. 30 Day Supply

The Vimerson Nattokinase Supplement is designed to support your cardiovascular health with its high potency of 4000 FU enzyme activity. You can enjoy improved circulation as it helps maintain normal fibrinogen levels, which is essential for smooth blood flow. Crafted with care from non-GMO soybeans, this supplement ensures you receive pure and effective nattokinase enzymes. Plus, the convenient capsule form allows you to reap the benefits of Japanese natto without any unpleasant taste or smell, making it easy to incorporate into your daily routine.

What We Like
Supports cardiovascular health
Promotes healthy circulation
Non-GMO and vegan
Easy-to-swallow capsules
#TOP 3

Doctor's Best Nattokinase Enzyme for Heart & Circulatory Health

DRB-00125
Doctor's Best Nattokinase Enzyme for Heart & Circulatory Health Cover
Doctor's Best Nattokinase 2,000 Fu, Non-GMO, Gluten Free, Vegan, Supports Cardiovascular and Circulatory Health, 90 VC

Doctor's Best Nattokinase is a vegan, non-GMO supplement derived from natto, a traditional fermented soy food popular in Japan. It contains pure nattokinase enzyme with Vitamin K2 removed, which has been shown to support a healthy circulatory system by helping to maintain normal fibrinogen levels in blood. Nattokinase can also support heart and circulatory health by promoting better blood flow. Customers should be available during delivery as exposure to heat or sunlight can damage the product.

What We Like
Vegan and non-GMO ingredients
Supports a healthy circulatory system by helping to maintain normal fibrinogen levels in blood
Promotes better blood flow for heart and circulatory health
#TOP 4

NatureBell Nattokinase 8,000 FU

BA-NB-NK240C
NatureBell Nattokinase 8,000 FU Cover
NatureBell Nattokinase Supplement 8,000 FU Per Serving, 240 Veggie Capsules | Traditional Natto Extract Source – Max Strength Enzyme & Heart Health Support – Non-GMO

The NatureBell Nattokinase supplement offers a powerful dose of 8,000 FU per serving, derived from traditional fermented Natto extract, a revered ingredient in Japanese cuisine. With 240 vegetarian capsules in each bottle, you can easily incorporate three capsules daily for optimal heart health support. This supplement is designed to promote overall wellness, making it a great addition to your daily routine. NatureBell ensures that you receive the genuine benefits of Nattokinase, which has been valued for centuries, while also providing a non-GMO product free from common allergens.

What We Like
High enzyme potency
Supports heart health
240 capsules per bottle
Non-GMO and allergen-free
#TOP 5

Enzymedica SerraGold Serrapeptase Supplement

26301
Enzymedica SerraGold Serrapeptase Supplement Cover
Enzymedica, SerraGold, High-Potency Serrapeptase Enzyme Supplement, Supports Respiratory, Heart & Immune Function, 120 Count

Enzymedica SerraGold Supplement offers whole-body support for mobility, immunity, and heart health. Its high-potency serrapeptase works effectively without the need for enteric coating, making it gentle on your stomach. You can take it easily on an empty stomach, allowing the systemic enzymes to enter your bloodstream and reach targeted cells and tissues. This means you can enjoy the benefits beyond just digestion. With a focus on clean ingredients and scientific validation, this supplement simplifies maintaining your health and well-being.

What We Like
Whole-body support
Gentle on the stomach
Systemic enzyme benefits
Clean, effective ingredients
#TOP 6

Arthur Andrew Medical Nattovena Nattokinase

Arthur Andrew Medical Nattovena Nattokinase Cover
Arthur Andrew Medical - Nattovena, Pure Nattokinase, Circulatory and Heart Health, Vegan, Non-GMO, 30 Capsules

Nattovena Nattokinase by Arthur Andrew Medical is a powerful supplement designed to support your heart and circulatory health. This product helps cleanse your blood of fibrin, which can improve circulation and reduce discomfort from fatigue and joint pain. Each capsule contains over 4,000 fibrinolytic units, ensuring effective action without the need for special coatings. As a naturally derived enzyme from fermented soybeans, it offers a safe way to replenish essential enzymes that may diminish with age, promoting overall well-being.

What We Like
Supports circulatory health
Reduces joint discomfort
High fibrinolytic potency
Natural and vegan ingredients
#TOP 7

Enzymedica Natto-K Nattokinase Supplement

22090
Enzymedica Natto-K Nattokinase Supplement Cover
Enzymedica, Natto-K, Nattokinase Supplement, Promotes Heart Health & Circulation, 90 Count

Enzymedica Natto-K is designed to support heart health and improve circulation. This supplement features a unique blend of enzymes, including clinically studied nattokinase, which helps break down unwanted proteins in your bloodstream, promoting better blood flow. Taking it on an empty stomach allows these enzymes to reach the bloodstream and target specific cells, enhancing their effectiveness. With a simple dosage of just one capsule three times a day, it’s easy to incorporate into your routine. Plus, it’s free from gluten and artificial additives, making it a clean choice for your health.

What We Like
Supports heart health
Enhances circulation
Easy dosage schedule
Free from artificial additives

Wholesome Wellness Digestive Enzymes

digestive-enzymes
Green
Wholesome Wellness Digestive Enzymes Cover
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

What We Like
Relieves bloating and constipation
Plant-based vegan formula
Improves gut health
May enhance sleep, digestion, and energy
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What supplement removes plaque from arteries?

Niacin, or Vitamin B3, is the best agent known to raise blood levels of HDL, which helps remove cholesterol deposits from the artery walls.

2. Can CoQ10 heal your heart?

CoQ10 has been shown to improve symptoms of congestive heart failure. Although findings are mixed, CoQ10 might help reduce blood pressure. Some research also suggests that when combined with other nutrients, CoQ10 might aid recovery in people who've had bypass and heart valve surgeries.

3. Can CoQ10 reverse heart disease?

Patients diagnosed with congestive heart failure have been shown to have low levels of CoQ10, which can increase their chance of death by 50% within five years. Using the proper form and dose of CoQ10 can reverse these underlying pathologies and promote cardiovascular health and longevity.

Editor's Notes

During our enzyme supplement for heart health research, we found 24 enzyme supplement for heart health products and shortlisted 8 quality products. We collected and analyzed 104,263 customer reviews through our big data system to write the enzyme supplements for heart health list. We found that most customers choose enzyme supplements for heart health with an average price of $27.39.

The enzyme supplements for heart health are available for purchase. We have researched hundreds of brands and picked the top brands of enzyme supplements for heart health, including DEAL SUPPLEMENT, Vimerson Health, Doctor's BEST, NatureBell, Enzymedica. The seller of top 1 product has received honest feedback from 24,776 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.