Best Vitamin B12 Enzyme Supplements of 2025

Garden of Life 22 Digestive Enzymes for Women is a raw enzyme supplement designed to support the digestive and overall health needs of women with amplified potencies of carb-digesting enzymes. It has 22 digestive enzymes, probiotics, probiotic-created vitamins and minerals, and antioxidant enzymes to help process difficult-to-digest food and support colon, bone, and breast health, gut-related immunity, and digestion. The formula is Third-Party Non-GMO Project Verified, Certified Gluten-Free, Vegetarian, and Carbon Neutral.

Garden of Life Digestive Enzymes for Women 50+ is a non-GMO, gluten-free, vegetarian supplement that helps with digestion, colon, bone, and breast health, and gut-related immunity. It's designed to meet the needs of women aged 50 and over, with amplified potency of carb and protein-digesting enzymes, probiotics, probiotic-created vitamins, and minerals. The formula contains 22 digestive enzymes and antioxidant enzymes, and it's made according to the RAW standard, which means it's untreated, uncooked, and unaltered to preserve the activity levels of essential enzymes.

FRISKA Mens Daily Supplement is a powerful probiotic and digestive enzyme blend designed specifically for men. Enforced with lactase, it helps break down lactose sugar found in dairy products, making it ideal for those with lactose intolerance. The added B vitamins support brain and red blood cell function, promoting overall well-being. This supplement also includes digestive enzymes like amylase and lipase, as well as lactobacillus acidophilus probiotic, which provide relief from gut issues such as abdominal pain, bloating, and gas. By restoring gut health and maintaining healthy enzyme levels, FRISKA Mens Daily Supplement helps alleviate symptoms like diarrhea and bloating. Made from naturally sourced organic ingredients, this clean alternative is plant-based and easy to digest.

Dr. Clark Digestive Support offers optimal enzyme aid for your digestive health. These enzymes effectively break down fats, carbohydrates, and proteins, making it easier for your body to absorb nutrients. The product is formulated without any harmful manufacturing agents, coatings, or colorings, ensuring a clean supplement choice. Additionally, it contains no common allergens like soy, nuts, or milk, so you can take it with peace of mind. With 50 gelatin capsules, this supplement provides a convenient way to support your digestive system daily.

The Pure Encapsulations Betaine HCl Pepsin Digestive Enzyme supplement supports digestive function, nutrient absorption, and gut health. It contains Betaine HCL and pepsin, which are essential for food digestion and nutrient absorption. Betaine HCL also contributes to the acidic environment of the stomach, which is necessary for maintaining a healthy balance. The supplement is made with premium ingredients, and is free from common allergens, artificial colors, flavors, sweeteners, GMOs, and unnecessary fillers and preservatives.

MaryRuth's Ultra Digestive Food Enzymes is a vegan supplement formulated to enable digestion, especially in those with digestive issues, amplifying nutrient absorption while reducing bloating, gas and abdominal pain. This extra strength blend of enzymes are formulated to help digest proteins, carbohydrates, fiber, fat, and lactose. It includes Protease, Amylase, Glucoamylase, Diastase, Invertase, Pectinase, Cellulase, Hemicellulase, Xylanase, Lipase, Lactase, Alpha-Galactosidase, and Beta-Glucanase. It is Non-GMO & Vegan, Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Nightshade Free, Sugar Free, and contains Maltodextrin. Customers have reported that it works great and helps reduce bloating, gas, and abdominal pain.

Designs for Health Betaine HCl is a non-GMO supplement that supports digestive function and proper absorption of nutrients. With 750mg of betaine hydrochloride and pepsin, a key protein digestive enzyme, this product aids in the digestion of protein-containing foods and the assimilation of nutrients. By taking one capsule before a meal, you can improve your digestion and ensure the proper absorption of vitamins and minerals. The upgraded delivery system from tablet to capsule ensures that the betaine HCl and pepsin reach the stomach where they are needed to initiate digestion. Designs for Health Betaine HCl is a trusted choice for over 50,000 doctors, providing pure and effective products since 1989.

USAEnzymes HCL-XYM Enzymes is a multi-enzyme supplement that supports the body's natural ability to produce HCL, which can be compromised due to age or illness. It offers relief from occasional gas, bloating, and indigestion, while also supporting the digestion and absorption of food. By creating the proper pH in which protein-digesting enzymes work, it helps enhance the breakdown of proteins in the body. Additionally, USAEnzymes HCL-XYM Enzymes aids in extracting vitamin B12 from food and maintaining healthy intestinal flora levels. With these benefits, this supplement can help improve digestion and overall gut health, providing you with increased comfort and well-being.

The GIVOL Vitality Boost Spray is designed to enhance your overall well-being. It combines Vitamin B12 with a powerful Mushroom Complex, which can help improve your cognitive function and maintain a balanced lifestyle. You’ll appreciate the energy-boosting effects of Bromelain, which supports sustained vitality. This spray not only offers immediate benefits but also promotes long-term health, ensuring you feel vibrant and energized every day. Plus, it's free from gluten and sugar, making it a great choice for those with dietary restrictions, while providing a convenient 60-day supply for continuous wellness support.

Dr. Wolz Immunkomplex is a premium dietary supplement designed to support your immune system health. Packed with a blend of trace elements, including selenium, zinc, lycopene, and broad-spectrum vitamins, this formula helps fortify your immune system. By fighting oxidative stress with its natural antioxidants, it can also slow signs of aging and reduce the effects of damaging UV sun rays. In addition, it contains vitamins B2, B6, B12, niacin, and pantothenic acid to reduce fatigue and restore energy, making it ideal for those with a weakened immune system. Free of lactose, colorants, or preservatives, Dr. Wolz Immunkomplex is a broad-spectrum formula that supports your well-being inside and out.