Best Chewable Enzyme Supplements of 2025

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Chewable enzyme supplements are a popular way to improve digestion and overall gut health. These supplements are designed to be chewed before meals, allowing the enzymes to mix with food and aid in the breakdown of proteins, carbohydrates, and fats. They are a convenient option for people who may have trouble swallowing pills or who want a more natural alternative to traditional digestive aids. Chewable enzyme supplements can also be a helpful addition to a healthy diet, as they can increase nutrient absorption and reduce digestive discomfort.
At a Glance: Our Top Picks
Top 10 Chewable Enzyme Supplements
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets are a great-tasting, vegetarian formula that helps with digestion and nutrient absorption. It contains papain and other enzymes, as well as peppermint and chlorophyll to freshen breath and reduce bad taste. Customers have found it to be helpful with inefficient digestion, nausea, upset stomach, acid reflux, and digestion. It is gluten-free, wheat-free, lactose-free, egg-free, preservative-free, yeast-free, milk-free, soy-free, grapefruit-free, sodium-free, and artificial color-free.
Garden of Life Dr Formulated Digestive Enzymes
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.
American Health Original Papaya Digestive Enzyme Chewable Tablets
American Health Original Papaya Digestive Enzyme Chewable Tablets are a great after-meal supplement that helps promote nutrient absorption and digestion. It contains chlorophyll and peppermint to freshen breath. Customers have praised the product for its effectiveness in relieving acid reflux, bloating, and indigestion. It is vegan, gluten-free, and comes in a 600 count bottle.
American Health Papaya Enzyme with Chlorophyll Chewable Tablets
American Health Papaya Enzyme with Chlorophyll Chewable Tablets is a great after meal supplement that helps promote nutrient absorption and freshens breath. It is gluten free and comes in a 600 count bottle. Customers have reported that it works great for settling their tummy and avoiding indigestion. It is also a natural papaya enzyme that can be used as a minty mouth freshener.
21st Century Papaya Enzyme Chewable Tablets
21st Century Papaya Enzyme Chewable Tablets are a great way to support your digestive system. These chewable tablets are gluten-free, contain no added salt, yeast, preservatives, or artificial flavors, and are suitable for all stages. Customers have reported that the tablets taste good, work well, and are a great option for those with gastric bypass surgery.
Dr Amy Myers Digestive Enzymes Chewable – 180 Tablets
Dr Amy Myers Digestive Enzymes Chewable is a powerful formula with nearly 20 different enzymes that help you digest food more easily. It is useful for breaking down various types of food such as proteins, dairy products, legumes, sugars, carbohydrates, fats, and fibers. It also helps you feel better quickly after an accidental or overload exposure to gluten. Moreover, it decreases fatigue and increases energy by breaking down the food more quickly and efficiently. It is free of soy, dairy, artificial sweeteners, and gluten. Plus, it is Dr. Amy Myers approved and guaranteed.
American Health Super Papaya Enzyme Chewables
American Health Papaya Enzyme offers advanced digestive support through naturally-sourced enzymes. These chewable tablets help your body absorb nutrients effectively, making them beneficial for digesting proteins, carbohydrates, and fats. Enjoying these tasty wafers after meals can enhance your digestive comfort. Additionally, the peppermint flavor not only freshens your breath but also masks any unpleasant aftertaste. With no GMOs or artificial ingredients, this product is a convenient and health-conscious choice for anyone seeking to improve their digestion.
NOW ChewyZymes
NOW Digestive Enzymes are designed to support optimal digestion of meals. With a broad spectrum of digestive enzymes, it helps break down carbohydrates, proteins, and fats into smaller, more easily absorbed nutrients. The natural berry flavor of the vegetarian chewable tablet makes it great for both adults and kids. This supplement is also Vegan/Vegetarian, Soy Free, Keto Friendly, Dairy Free. NOW Digestive Enzymes are GMP Quality Assured. It means that every aspect of the NOW manufacturing process has been examined, including laboratory/testing methods for stability, potency, and product formulation. Customers should be available during the product delivery to avoid melting or damage of the product caused by exposure to heat or sunlight.
Carlyle Papaya Enzyme Chewable Tablets
Carlyle Papaya Enzyme Chewable Tablets are a vegetarian, non-GMO, gluten-free formula with a tropical flavor. This precise blend of enzymes Protease, Amylase, Bromelain, & Lipase helps to reap the nutritional benefits of Papaya fruit. Customers have found it to be helpful for stomach upsets, heartburn, indigestion, and constipation. It is also great for rabbits!
Yuve Natural Papaya Digestive Enzymes
Yuve Natural Papaya Digestive Enzymes are sugar-free chewable candies that promote better digestion, aid in constipation and bloating relief, and help with detoxing and leaky gut repair. These vegan, non-GMO, and gluten-free enzymes are great for those looking to lose weight or lead an active lifestyle. Customers have reported improved digestion, reduced bloating, and increased energy levels after taking these enzymes.
Frequently Asked Questions (FAQs)
1. Do chewable digestive enzymes work?
It's for this reason that digestive enzyme supplements have been getting attention lately—there is speculation that they boost those processes and help relieve symptoms of indigestion. But the clinical evidence shows that digestive enzymes are not effective at alleviating gas or bloating.
2. What do chewable enzymes do?
Assist in the breakdown of protein into constituent amino acids. Support maximum calcium, magnesium, iron, and other mineral absorption. Help to activate pancreatic enzymes. Maintain healthy gastrointestinal microbe balance and immunity.
3. What are the benefits of taking enzyme supplements?
Proteolytic enzymes have many important functions in the body, including helping break down food for energy, and are found in certain foods and supplements. Studies suggest that they can improve digestion, decrease inflammation, ease arthritis pain and possibly reduce symptoms related to IBS.
4. Is it good to take enzyme supplements?
“Overall, a healthy person really doesn't need to take digestive enzyme supplements,” Denhard explains. “The best digestive enzymes are the ones our bodies make naturally, and they work best when you eat a whole food diet.”
During our chewable enzyme supplement research, we found 24 chewable enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 193,664 customer reviews through our big data system to write the chewable enzyme supplements list. We found that most customers choose chewable enzyme supplements with an average price of $13.45.
The chewable enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of chewable enzyme supplements, including American Health, Garden of Life, 21st Century, Amy Myers MD, NOW Foods. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.