Best Powder Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 30, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Powder enzyme supplements are a popular option for those looking to improve their digestive health. These supplements are typically made from a blend of natural enzymes, such as amylase and protease, which help to break down carbohydrates, proteins, and fats in the body. They come in a powder form, which can be easily mixed into food or drinks for convenient consumption. Powder enzyme supplements are especially beneficial for those with digestive issues, as they can help to alleviate symptoms such as bloating and gas. They are also a great way to support overall gut health and ensure proper nutrient absorption.

At a Glance: Our Top Picks

Dr. Berg's Gallbladder Formula Cover #TOP 1
Dr. Berg's Gallbladder Formula
ftb score rating icon 9.9
Lovebug Toddler & Kids Probiotics Cover #TOP 2
Lovebug Toddler & Kids Probiotics
ftb score rating icon 9.8
FODZYME Home Kit Digestive Enzymes 60 Dose Cover #TOP 3
FODZYME Home Kit Digestive Enzymes 60 Dose
ftb score rating icon 9.6

Top 3 Powder Enzyme Supplements

#TOP 1

Dr. Berg's Gallbladder Formula

Dr. Berg's Gallbladder Formula Cover
Dr. Berg Gallbladder Formula Extra Strength - with Ox Bile Powder and Conjugated Bile Acid - Digestive Enzymes Proprietary Blend - Full 45-Day Supply - 90 Vegetable Capsules

Dr. Berg's Gallbladder Formula is a powerful enzymatic supplement designed to promote healthy levels of bile salts and a healthy flow of bile. It is made with state-of-the-art manufacturing facilities and high-quality ingredients sourced from domestic and international farms. It comes with a 30-day money-back guarantee and is suitable for keto dieters. Customers have reported relief from bloating, indigestion, abdominal swelling, and constipation.

What We Like
Improved fat digestion
Reduced bloating and discomfort
Quick relief after meals
Helps post-gallbladder removal
Natural ingredients

Lovebug Toddler & Kids Probiotics

LOVEBUG
LBP20221
30 Pack (Pack of 1)
Lovebug Toddler & Kids Probiotics Cover
Lovebug Kids Probiotic Powder with Prebiotic Fiber - Toddler Immunity Support & Constipation Relief - USDA Organic Probiotics for Childrens Gut & Digestive Health (Ages 1-4) - 30 Pack (Unflavoured)

Lovebug Probiotics offers a specialized blend of 8 probiotic strains tailored for toddlers and young children aged 12 months to 4 years. The formulation aims to address digestive upsets, diarrhea, and constipation common in this age group. By providing 15 billion active cultures, including Lactobacillus GG, it supports digestive and immune health. Lovebug Probiotics is non-GMO, gluten-free, and free from artificial colors or flavors, ensuring a safe option for your child's well-being.

What We Like
Improves toddler digestion
Easy to mix and use
Gentle and allergen-free formula
Supports regularity and gut health
Kid-approved taste and texture

FODZYME Home Kit Digestive Enzymes 60 Dose

FODZYME
FODZYME Home Kit Digestive Enzymes 60 Dose Cover
FODZYME® Home Kit Digestive Enzymes for Gut Health, Relief for Bloating, Gas, Constipation, Diarrhea, Abdominal Pain, Low FODMAP, 60 Dose

The FODZYME Digestive Enzymes help you enjoy foods that usually cause gut discomfort, like garlic, onion, or bread, by breaking down the hard-to-digest parts. This means you can eat without worrying about bloating or gas. The formula is packed with a special enzyme called fructan hydrolase that targets fructans found in many carbs, making digestion easier for your stomach. Unlike capsules, this product comes in a tasteless powder that you mix directly with your food, so it starts working right away to support smoother digestion. Plus, it’s backed by scientific studies and created by experts to help with common gut problems caused by FODMAPs.

What We Like
Breaks down high-FODMAP foods
Contains powerful fructan enzyme
Instant-action powder form
Scientifically validated formula
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is enzyme supplement good for?

Over-the-counter digestive enzyme supplements are meant to help ease issues with digestion caused by Crohn's disease, celiac disease, heartburn, irritable bowel syndrome (IBS), ulcerative colitis, and indigestion.

2. What are the 3 best digestive enzymes?

The most important can include protease to help break down proteins, lipase to help with fats, and amylase to help digest carbohydrates. We recommend supplements with at least three types of enzymes.

3. When should I take an enzyme supplement?

Enzymes Should be Taken with Food It's crucial to take enzymes as directed. That means, in most cases, you should take digestive enzyme supplements along with food. In many instances, they should be taken in combination with specific foods in order to properly perform their intended function.

Editor's Notes

During our powder enzyme supplement research, we found 24 powder enzyme supplement products and shortlisted 3 quality products. We collected and analyzed 288,027 customer reviews through our big data system to write the powder enzyme supplements list. We found that most customers choose powder enzyme supplements with an average price of $23.09.

The powder enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of powder enzyme supplements, including Dr. Berg Nutritionals, LOVEBUG, FODZYME. The seller of top 1 product has received honest feedback from 4,762 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.