Best Powder Enzyme Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Powder enzyme supplements are a popular option for those looking to improve their digestive health. These supplements are typically made from a blend of natural enzymes, such as amylase and protease, which help to break down carbohydrates, proteins, and fats in the body. They come in a powder form, which can be easily mixed into food or drinks for convenient consumption. Powder enzyme supplements are especially beneficial for those with digestive issues, as they can help to alleviate symptoms such as bloating and gas. They are also a great way to support overall gut health and ensure proper nutrient absorption.

At a Glance: Our Top Picks

Vital Nutrients GI Repair Powder Cover #TOP 1
Vital Nutrients GI Repair Powder
ftb score rating icon 9.9
Hilma Daily Fiber with Enzymes Cover #TOP 2
Hilma Daily Fiber with Enzymes
ftb score rating icon 9.8
Complete Natural Products Organic Papaya Enzyme Capsules Cover #TOP 3
Complete Natural Products Organic Papaya Enzyme Capsules
ftb score rating icon 9.6

Top 10 Powder Enzyme Supplements

#TOP 1

Vital Nutrients GI Repair Powder

Vital Nutrients GI Repair Powder Cover
Vital Nutrients GI Repair Powder | Leaky Gut Powder with L Glutamine and Zinc | Digestive Enzyme Supplement to Support Gut Health and Digestion | Gluten Free | 40 Servings

Vital Nutrients GI Repair is a digestive enzyme supplement that supports gut health and digestion. It contains L-Glutamine and N-Acetyl Glucosamine (NAG) which promote the growth and health of the gastrointestinal lining, helping to maintain normal intestinal permeability. This can be beneficial for individuals with leaky gut syndrome. The supplement also soothes the mucus membrane of the digestive tract lining, providing relief from bloating. With the addition of botanicals, Zinc, amino acids, and a stable probiotic, Vital Nutrients GI Repair provides fuel, protection, and structural support for the cells of the GI tract. It is free from coatings, binders, gluten, soy protein, egg protein, and sugar. Vital Nutrients goes above and beyond FDA testing requirements, ensuring the quality and safety of their products.

What We Like
Promotes gut health
Soothes digestion and relieves bloating
Contains botanicals and Zinc for GI tract support
#TOP 2

Hilma Daily Fiber with Enzymes

Hilma Daily Fiber with Enzymes Cover
Hilma Daily Fiber + Digestive Enzymes – Fiber Supplement Powder with Prebiotics & Enzymes Formulated with Psyllium Husk & Acacia - Gluten Free, Vegan, FSA Eligible - Digestive Support - 30 Servings

Hilma Daily Fiber is a fiber supplement designed to support your digestive health. It contains prebiotic fibers, like acacia and psyllium husk, that deliver six grams of natural fiber per serving, helping to keep your digestive system regular. The included digestive enzymes work in tandem with the fiber to ease discomfort and reduce bloating, making it ideal for sensitive stomachs. Easy to use, simply mix two teaspoons into water, smoothies, or yogurt for a convenient boost to your daily routine. Hilma’s commitment to natural remedies ensures you receive a product that is both effective and safe.

What We Like
Supports digestive health
Contains prebiotic fibers
Reduces bloating discomfort
Easy to mix and consume
Vegan and gluten-free

Complete Natural Products Organic Papaya Enzyme Capsules

Complete Natural Products Organic Papaya Enzyme Capsules Cover
Complete Natural Products Organic Papaya Enzymes & Papain Enzyme Capsules - 500mg 100 Pills, Organic Papaya Powder Digestive Super Fruit Capsules

Complete Natural Products Organic Papaya Enzyme Capsules are made in the USA and certified USDA Organic & OU Kosher. These veggie caps are vegan and non-GMO herbal supplements that contain natural papain enzymes from papaya. Papaya supplements are a great source of vitamins A, B, C, and K and are known as an excellent immunity booster. These capsules are high in fiber and water content, which help prevent constipation and promote a smooth bowel movement. The enzyme papain present in organic papaya powder is known to aid digestion by breaking down proteins. Therefore, a couple of capsules of papaya powder are often recommended as a home remedy for digestion-related problems and gut health.

What We Like
USDA Organic & OU Kosher certified
Vegan and non-GMO
High in fiber and water content
Contains natural papain enzymes from papaya
Great source of vitamins A, B, C, and K
#TOP 4

BULKSUPPLEMENTS.COM Papaya Extract Powder

PAPFRUIT100
BULKSUPPLEMENTS.COM Papaya Extract Powder Cover
BulkSupplements.com Papaya Fruit Extract Powder - from Carica Papaya, Papaya Extract - for Digestive Support, Papaya Powder - Gluten Free, 1000mg per Serving, 100g (3.5 oz) (Pack of 1)

BULKSUPPLEMENTS.COM Papaya Extract is a high-quality papaya fruit extract powder that is packed with antioxidants and essential vitamins and minerals. With its pure and gluten-free formula, it is suitable for those with dietary restrictions. This papaya extract powder is not only beneficial for overall health, but it also promotes skin health due to its lycopene and Vitamin C content. Adding this papaya powder to your daily routine can help keep your skin looking healthy. Additionally, it can be easily incorporated into your diet as a versatile ingredient. With its high quality and adherence to cGMP standards, BULKSUPPLEMENTS.COM Papaya Extract ensures consistency and reliability.

What We Like
Packed with antioxidants
Great for skin health
Pure and gluten-free
#TOP 5

Royal Tropics Pineapple Bromelain Digestive Enzyme Supplements

Light Green
Royal Tropics Pineapple Bromelain Digestive Enzyme Supplements Cover
Pineapple Bromelain Digestive Enzyme Supplements a Blend of Green Papaya Powder and Bromelaine 350 Grams

Royal Tropics Digestive Enzyme Supplements is a powerful blend of Green Papaya Enzyme Powder with Papain and Bromelain, derived from the fruit and stem of the Pineapple. This multi-enzyme supplement supports better digestion by assisting the digestive system to work more efficiently and consume less energy while processing food. The Green Papaya Enzyme Powder with Papain aids in breaking down proteins and supports the digestion process. Bromelain, a proteolytic enzyme, further enhances digestion. With this combination blend of enzymes, Royal Tropics Digestive Enzyme Supplements can help improve your digestion and bring convenience and benefits to your overall digestive health.

What We Like
Supports better digestion
Efficient digestion process
Enhances overall digestive health

BulkSupplements Papaya Powder

PAPYPWD
BulkSupplements Papaya Powder Cover
BulkSupplements.com Papaya Powder - Bone Marrow Supplements - Papaya Digestive Enzymes - Immune Boost - Organic Extracts (1 Kilogram - 2.2 lbs)

BulkSupplements Papaya Digestive Enzymes is a high-quality, pure and natural supplement that offers a range of benefits. Packed with antioxidants, it supports a healthy immune system and aids in digestion. The vitamins A and C in the papaya powder contribute to maintaining healthy skin, while the papain enzyme has anti-inflammatory effects and can improve skin elasticity. Additionally, the vitamin B6 in the papaya extract promotes heart health by supporting energy metabolism and reducing fatigue. This gluten-free and dairy-free supplement is manufactured according to cGMP Standards, ensuring the highest quality. With no fillers or additives, BulkSupplements Papaya Digestive Enzymes is a convenient way to enjoy all the benefits of papaya.

What We Like
Rich in antioxidants
Promotes healthy skin
Contributes to heart health

Codeage Digestive Enzymes Supplement

Fermented Enzymes
Codeage Digestive Enzymes Supplement Cover
Codeage Fermented Digestive Enzymes Supplement 3-Month Supply - 14 Digestive Enzymes, Probiotics, Prebiotics, Fermented Botanicals, Plant-Based Multi Pancreatic Enzymes - 1 Capsule a Day - 90 Capsules

Codeage Digestive Enzymes Supplement is an all-in-one digestive enzymes solution featuring raw & vegan digestive enzymes paired with probiotics, prebiotics, fermented botanical fruits, and herbs. It contains 14 enzymes, a fermented organic botanical blend, and a probiotics blend of 4 different strains. It is made with non-GMO ingredients in the USA in a cGMP certified facility and is vegan and contains no soy, gluten, milk, egg, wheat, shellfish, color additives, or preservatives.

What We Like
Contains 14 enzymes
Organic botanical blend
Probiotics blend
Vegan & Non-GMO
#TOP 8

Earth Circle Organics Papaya Seed Capsules

Earth Circle Organics Papaya Seed Capsules Cover
Earth Circle Organics Papaya Seed Powder Capsules – Powerful Papain Supplement & Other Enzymes for Digestion and Gut Health - 360mg/ Serving – 60 Vegan Capsules (Pack of 2)

Earth Circle Papaya Capsules offer a pure and potent source of papaya seed nutrition. These capsules are soy-free and contain no fillers or artificial additives, ensuring you consume only what is beneficial. The seeds are carefully processed to retain their nutrients, providing you with a high enzyme count that supports digestion and gut health. Each serving is packed with vitamins, minerals, and antioxidants, promoting not just digestive wellness but also enhancing the health of your skin, hair, and nails. You can feel confident in your purchase, as the product comes with a satisfaction guarantee.

What We Like
100% pure ingredients
Supports digestion and gut health
High enzyme count
Vegan-friendly
Satisfaction guarantee
#TOP 9

O! MY ENZYME Digestive Supplement by tomnada

tomnada
O! MY ENZYME Digestive Supplement by tomnada Cover
O! MY ENZYME Fermented Enzyme Supplement Powder Sticks with Probiotics for Healthy Digestion Immune Support, Amylase Protease Beta-carotene, Anti-oxidant Enzymes Digestive Supplement, 30 Sticks

O! MY ENZYME by tomnada is designed to enhance your digestive health with its unique blend of fermented enzymes and probiotics. These patented ingredients work together to help your body break down fats, carbohydrates, and proteins, leading to improved nutrient absorption and increased energy levels. Additionally, the inclusion of a super fruit, cataloupe melon, provides a rich source of beta-carotene and antioxidant support. If you often experience gas and bloating, this supplement can help alleviate those uncomfortable feelings by making digestion more efficient. Enjoy better gut health and overall wellness with this powerful supplement.

What We Like
Enhanced digestion
Improved nutrient absorption
Gas and bloating relief
Contains antioxidants
#TOP 10

Betaine HCl Powder

N1R3TPZ
Betaine HCl Powder Cover
BulkSupplements.com Betaine HCl Powder - Betaine Hydrochloride Powder, Betaine HCl 750mg, Betaine Hydrochloride Supplement - Gluten Free, 750mg per Serving, 500g (1.1 lbs) (Pack of 1)

Looking to optimize your digestion and gut health? Try BULKSUPPLEMENTS.COM Betaine HCl Powder! This high-quality digestive enzyme supplement is packed with 750mg of Betaine HCl per serving, which supports a healthy digestive system and promotes optimal nutrient absorption. By adding this pure and filler-free Betaine HCl powder to your daily routine, you can ensure that your body is getting the most out of the nutrients in your diet. Plus, with its cGMP manufacturing standards and third-party testing, you can trust the quality and consistency of this Betaine HCl supplement. Say goodbye to digestive issues and hello to a healthier gut with BULKSUPPLEMENTS.COM Betaine HCl Powder!

What We Like
Optimizes digestion
Promotes healthy gut flora
Supports nutrient absorption
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is enzyme supplement good for?

Over-the-counter digestive enzyme supplements are meant to help ease issues with digestion caused by Crohn's disease, celiac disease, heartburn, irritable bowel syndrome (IBS), ulcerative colitis, and indigestion.

2. What are the 3 best digestive enzymes?

The most important can include protease to help break down proteins, lipase to help with fats, and amylase to help digest carbohydrates. We recommend supplements with at least three types of enzymes.

3. When should I take an enzyme supplement?

Enzymes Should be Taken with Food It's crucial to take enzymes as directed. That means, in most cases, you should take digestive enzyme supplements along with food. In many instances, they should be taken in combination with specific foods in order to properly perform their intended function.

Editor's Notes

During our powder enzyme supplement research, we found 24 powder enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 11,044 customer reviews through our big data system to write the powder enzyme supplements list. We found that most customers choose powder enzyme supplements with an average price of $20.23.

The powder enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of powder enzyme supplements, including Vital Nutrients, Hilma, Complete Natural Products, BulkSupplements, Royal Tropics. The seller of top 1 product has received honest feedback from 55,046 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.