Best Capsule Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 30, 2026

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Capsule enzyme supplements are a type of dietary supplement that contain enzymes to help the body break down and digest food more efficiently. These enzymes can help people who struggle with digestive issues or who want to improve their overall digestion. The supplements come in easy-to-swallow capsules and can be taken with meals or as directed by a healthcare professional. There are many different types of enzyme supplements available, each designed to target specific types of food or digestive issues. Overall, capsule enzyme supplements offer a convenient and effective way to support healthy digestion.

At a Glance: Our Top Picks

NOW Supplements Super Enzymes Cover #TOP 1
NOW Supplements Super Enzymes
ftb score rating icon 9.9
NOW Foods Quercetin with Bromelain Cover #TOP 2
NOW Foods Quercetin with Bromelain
ftb score rating icon 9.8
Double Wood Nattokinase Supplement Cover #TOP 3
Double Wood Nattokinase Supplement
ftb score rating icon 9.6

Top 10 Capsule Enzyme Supplements

NOW Supplements Super Enzymes

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NOW Supplements Super Enzymes Cover
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

NOW Supplements Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion. Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein. It is Soy Free, Made without Gluten, Keto Friendly and GMP Quality Assured. Customers have reported that it helps with digestive issues, bloating, slow metabolism, and acid indigestion. It is easy to swallow and comes in capsule form.

What We Like
Improved digestion and gut health
Reduces gas and bloating
Supports fat and nutrient absorption
Affordable and reliable formula
Helps after gallbladder removal
#TOP 2

NOW Foods Quercetin with Bromelain

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NOW Foods Quercetin with Bromelain Cover
NOW Foods Supplements, Quercetin with Bromelain, Balanced Immune System*, 240 Veg Capsules

NOW Foods Quercetin Supplement is designed to support your immune system. Quercetin is a natural antioxidant that helps maintain healthy immune responses, especially during seasonal changes. By promoting normal respiratory function, it can assist you in breathing easier when environmental factors challenge your health. The addition of Bromelain enhances this effect, contributing to a balanced immune response. This product is also suitable for various dietary preferences, being vegan, non-GMO, and free from common allergens like gluten and dairy, making it a convenient choice for many users.

What We Like
Immune system support
Effective for allergies and sinus
Easy-to-swallow capsules
High quality and trustworthy brand
Good value, large bottle

Double Wood Nattokinase Supplement

Double Wood Nattokinase Supplement Cover
Nattokinase Supplement 4,000 FU Servings, 120 Capsules (Derived from Japanese Natto) Systemic Enzymes for Cardiovascular and Circulatory Support by Double Wood

Double Wood Nattokinase Supplement is a powerful systemic enzyme supplement that promotes cardiovascular and circulatory health. Derived from Japanese Natto, this supplement contains Nattokinase, which helps lower plasma levels of certain proteins that affect circulation. By doing so, it supports a healthy circulatory system. Research suggests that Nattokinase may also have a positive impact on cardiovascular health. With 120 capsules, each containing 200mg of Nattokinase, this two-month supply is ideal for long-term use. Manufactured and tested in the USA, this vegan-safe supplement is gluten-free and non-GMO, making it a reliable choice for those looking to support their cardiovascular and circulatory health.

What We Like
High quality supplement
Supports heart health
Easy to use
Reasonable price
Helps digestion
#TOP 4

Pure Encapsulations Digestive Enzymes Ultra

Pure Encapsulations Digestive Enzymes Ultra Cover
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Pure Encapsulations Digestive Enzymes Ultra is a multi-enzyme supplement that supports the break down of protein, carbohydrate, fiber, and dairy*, while promoting optimal nutrient bioavailability and absorption*. The supplement contains a broad profile of digestive enzymes, providing optimal activity across a wide pH range. Pure Encapsulations uses only premium ingredients, and the product is free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Improved digestion and regularity
Reduces bloating and discomfort
Comprehensive enzyme blend
Vegetarian and allergen-free formula
Small, easy-to-swallow capsules
#TOP 5

Dr. Berg's Gallbladder Formula

Dr. Berg's Gallbladder Formula Cover
Dr. Berg Gallbladder Formula Extra Strength - with Ox Bile Powder and Conjugated Bile Acid - Digestive Enzymes Proprietary Blend - Full 45-Day Supply - 90 Vegetable Capsules

Dr. Berg's Gallbladder Formula is a powerful enzymatic supplement designed to promote healthy levels of bile salts and a healthy flow of bile. It is made with state-of-the-art manufacturing facilities and high-quality ingredients sourced from domestic and international farms. It comes with a 30-day money-back guarantee and is suitable for keto dieters. Customers have reported relief from bloating, indigestion, abdominal swelling, and constipation.

What We Like
Improved fat digestion
Reduced bloating and discomfort
Quick relief after meals
Helps post-gallbladder removal
Natural ingredients

Nutricost Bromelain 500mg, 120 Vegetarian Capsules

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Nutricost Bromelain 500mg, 120 Vegetarian Capsules Cover
Nutricost Bromelain 500mg, 120 Vegetarian Capsules - Bromelain (1200 GDU), Non-GMO, Gluten Free

Get 120 servings of high-grade bromelain with Nutricost Bromelain 500mg. Each capsule contains 500mg of bromelain with 2,400 GDU per gram, ensuring you get the best quality. The product is non-GMO, vegetarian, gluten-free, and 3rd party tested. It is manufactured in a GMP compliant, FDA registered facility.

What We Like
Easy to swallow capsules
Helps with inflammation
Supports digestion and recovery
No stomach upset
Vegetarian and gluten free

Zenwise Probiotic Digestive Multi Enzymes

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Zenwise Probiotic Digestive Multi Enzymes Cover
Zenwise Health Digestive Enzymes for Gut Health & Bloating Relief - Multi Enzymes Digestion Supplement with Probiotics, Bromelain & Papaya for Digestive Health Support - Men & Women - 180 Count

Zenwise Health's Probiotic Digestive Multi Enzymes is a pre-meal plant-powered pill formulated to help women and men find relief from occasional bloating, gas, and discomfort. This advanced enzyme + prebiotic, probiotic non-GMO formula tackles hard-to-digest foods and is clinically proven to be reliably alive. It contains botanical bounty such as turmeric, ginger, green papaya, inulin, apple pectin, bladderwrack, fennel, and wakame to aid gut health and stomach comfort. Each bottle contains 180 capsules, and it is suggested to take one capsule before each meal.

What We Like
Improved digestion
Reduced bloating
Easy to swallow
No unpleasant taste or smell
Effective with difficult foods
#TOP 8

NOW Bromelain Supplements

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NOW Bromelain Supplements Cover
NOW Foods Supplements, Bromelain (Natural Proteolytic Enzyme) 2,400 GDU/g - 500 mg, Natural Proteolytic Enzyme*, 120 Veg Capsules

NOW Supplements, Bromelain is a natural proteolytic enzyme derived from pineapple plants that helps support healthy digestion and joint comfort. With 2400 GDU/g - 500 mg, it has protein-digesting properties that can relieve temporary soreness associated with muscle overuse. It is designed to support proper gastrointestinal function and may also promote the comfort of muscles and joints. The supplement is soy-free, vegan/vegetarian, nut-free, gluten-free, dairy-free, and keto-friendly. NOW guarantees quality assurance with GMP certification, and the product is packaged in the USA.

What We Like
Gentle on stomach
Anti-inflammatory benefits
Easy to swallow capsules
Affordable price
Convenient for daily use
#TOP 9

HUM Flatter Me Gut Health Supplement

HUM
016S
HUM Flatter Me Gut Health Supplement Cover
HUM Flatter Me Digestive Enzymes for Women & Men, Digestive Health Bloating Supplement with Ginger & Peppermint Leaf, Fast Acting Anti Bloat Pills Multi Enzyme for Debloating, Vegan, 60 Capsules

HUM Flatter Me Gut Health Supplement is an anti-bloating formula, containing 18 full-spectrum digestive enzymes, ginger, peppermint leaf, and fennel seed. It helps support digestion, soothe digestion, and support nutrient absorption. Take one capsule twice daily, before your two main meals, to reduce bloating. After only one use, 80% of users felt less bloating, and users also felt as much as 2 inches less bloating, according to a clinical study.

What We Like
Reduces bloating and discomfort
Improves digestion after heavy meals
Easy to swallow capsules
Quick noticeable results
Supports regular bowel movements

Sunergetic 4-in-1 Probiotic Supplement

PROB-4IN1-60
Sunergetic 4-in-1 Probiotic Supplement Cover
Premium 4-in-1 Probiotic Prebiotic, Postbiotic & Digestive Enzymes for Men & Women – Supports Gut, Digestion & Immunity –Complete Gut Health with Pre, Post, Probiotics & Digestive Enzymes–60 Capsules

The Sunergetic Probiotic Blend is a comprehensive gut health supplement designed for both men and women. It features a unique combination of probiotics, prebiotics, postbiotics, and digestive enzymes to support healthy digestion and intestinal health. By taking just two capsules daily, you can help reduce occasional gas and bloating, promoting overall gut comfort. Additionally, this formula supports immune health and regularity, making it easier for you to maintain digestive balance without the need for refrigeration. Its scientifically backed strains ensure you receive powerful support for your gut microbiome.

What We Like
Supports digestive health
Reduces bloating and gas
Easy-to-swallow capsules
Made in the USA
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What do enzyme capsules do?

People diagnosed with an enzyme insufficiency often need to take prescription digestive enzymes. These supplements help the body process food and absorb nutrients better.

2. What are the benefits of taking enzyme supplements?

Proteolytic enzymes have many important functions in the body, including helping break down food for energy, and are found in certain foods and supplements. Studies suggest that they can improve digestion, decrease inflammation, ease arthritis pain and possibly reduce symptoms related to IBS.

3. Why you shouldn't take digestive enzymes?

Digestive enzyme supplements also could interact with antacids and certain diabetes medications. They may cause side effects including abdominal pain, gas and diarrhea.

4. What are the 3 best digestive enzymes?

The most important can include protease to help break down proteins, lipase to help with fats, and amylase to help digest carbohydrates. We recommend supplements with at least three types of enzymes.

Editor's Notes

During our capsule enzyme supplement research, we found 24 capsule enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 629,663 customer reviews through our big data system to write the capsule enzyme supplements list. We found that most customers choose capsule enzyme supplements with an average price of $20.15.

The capsule enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of capsule enzyme supplements, including NOW Foods, Double Wood Supplements, Pure Encapsulations, Dr. Berg Nutritionals, Nutricost. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.