Best L-Arginine Supplements for Heart Health of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 13, 2026

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L-arginine supplements have been gaining popularity in recent years for their potential benefits in promoting heart health. L-arginine is an amino acid that helps the body produce nitric oxide, which can help improve blood flow and reduce inflammation in the arteries. Studies have shown that L-arginine supplements may help lower blood pressure, improve cholesterol levels, and reduce the risk of cardiovascular disease. These supplements are available in various forms, including pills, powders, and drinks. However, it is important to consult with a healthcare professional before taking L-arginine supplements, especially if you have a history of heart disease or are taking medication.

At a Glance: Our Top Picks

Snap Supplements Nitric Oxide Booster Cover #TOP 1
Snap Supplements Nitric Oxide Booster
ftb score rating icon 9.9
Nature's Pure Blend Nitric Oxide Supplement Cover #TOP 2
Nature's Pure Blend Nitric Oxide Supplement
ftb score rating icon 9.8
Puritan's Pride L-arginine Capsules Cover #TOP 3
Puritan's Pride L-arginine Capsules
ftb score rating icon 9.6

Top 8 L-Arginine Supplements for Heart Health

Snap Supplements Nitric Oxide Booster

FETEGT244
Snap Supplements Nitric Oxide Booster Cover
Snap Supplements Nitric Oxide Supplement with L-Arginine to Support Energy, Quick Recovery, Heart Health, Muscle Growth & Circulation, 90 Vegetarian Capsules

Snap Nitric Oxide Booster is designed to enhance your workout experience. It combines powerful ingredients like L-Arginine and L-Citrulline to promote better blood flow, which can help increase your stamina and endurance during exercises. You'll also appreciate the support for healthy blood pressure and lung capacity, making it easier to breathe and perform at your best. This supplement naturally boosts your energy levels before workouts and aids in muscle recovery afterward, ensuring that you feel refreshed and ready for your next session.

What We Like
Improved blood flow
Increased energy and endurance
Easy to take
Enjoyable taste (flavored version)
Clear health benefits
#TOP 2

Nature's Pure Blend Nitric Oxide Supplement

Nature's Pure Blend
Nature's Pure Blend Nitric Oxide Supplement Cover
Nature's Pure Blend Nitric Oxide Supplements for Men – L-Arginine L-Citrulline – Heart Support & Flow Circulation Booster – 1500MG L Arginine and L Citrulline, Preworkout, Bodybuilding

Nature's Pure Blend Nitric Oxide Supplement is a great solution for those who want to maintain their nitric oxide flow. Nitric Oxide is naturally produced by your body and it is important to take Nitric Oxide flow as we age since our bodies lose the ability to produce nitric oxide naturally. This supplement contains L-Arginine and L-Citrulline which are important amino acids for boosting nitric oxide production. The product is free from artificial ingredients, chemicals, and preservatives.

What We Like
Improved blood pressure support
Increased energy and stamina
Quality ingredients, no fillers
Positive impact on circulation
Responsive customer service

Puritan's Pride L-arginine Capsules

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Puritan's Pride L-arginine Capsules Cover
Puritan's Pride L-Arinine 1000mg, Dietary Supplement Supports Nitric Oxide Levels and Heart and Circulatory Heath, 100 Day Supply, 100 Tablets

Get the most out of your workouts and boost your immune system with Puritan's Pride L-arginine 1000 Mg Capsules. Arginine serves as a source of energy and supports exercise effects, and is one of the most important amino acids in immune function. Be mindful of product delivery as exposure to heat or sunlight may lead to melting or damage. This unflavored supplement comes in a bottle of 100 count capsules, making it convenient for adult use.

What We Like
Improved workout performance
Enhanced blood flow
No aftertaste
Easy to swallow
High-quality supplement

Nature's Bounty L-Arginine Tablets

Nature's Bounty L-Arginine Tablets Cover
Nature’s Bounty L-Arginine 1000mg for Supporting Blood Flow and Vascular Function – Non-GMO, Gluten Free, 50 Tablets

Improve your heart health with Nature's Bounty L-Arginine. This supplement supports nitric oxide synthesis and circulation, which helps to promote healthy blood flow and heart function. As a protein building block, it also contributes to healthy muscles. The tablets are vegetarian and gluten-free, making them easy to incorporate into any diet. However, customers are advised to be available during delivery to avoid heat or sunlight exposure, which may damage the product.

What We Like
Improved blood flow
Enhanced workout performance
Supports heart health
Increased male vitality
Non-GMO, no artificial additives
#TOP 5

Thorne Perfusia-SR L-Arginine Capsules

Thorne Research
Thorne Perfusia-SR L-Arginine Capsules Cover
THORNE - L-Arginine Sustained Release (Formerly Perfusia-SR) - Support Heart Function, Nitric Oxide Production & Optimal Blood Flow* - 60 Servings

Sustained-release Thorne Perfusia-SR L-arginine capsules support heart health, nitric oxide production, wound healing, immune function and optimal blood flow. With twice-daily dosing, these capsules promote relaxation of arteries and support lean muscle mass and work capacity during exercise. Additionally, every Thorne product is made with the purest possible ingredients, without gluten or other major allergens, soy, dairy, shellfish, or fish. Thorne adheres to the FDA’s current Good Manufacturing Practices (cGMPs) and has the highest number of NSF Certified for Sport products which tests for more than 200 banned substances for elite athletic competitions.

What We Like
Effective for blood pressure control
Natural supplement backed by research
No significant side effects
Trustworthy quality product
Improves bruising recovery time
#TOP 6

Pure Encapsulations L-Arginine Supplement

Pure Encapsulations L-Arginine Supplement Cover
Pure Encapsulations L-Arginine - 1,400 mg - Support Nitric Oxide Production - Heart Health & Blood Flow - Gluten Free & Non-GMO - 180 Capsules

The Pure Encapsulations L-Arginine supplement supports healthy blood flow by helping to dilate blood vessels. As an amino acid precursor of nitric oxide, it also helps with immune support, memory, and heart health. Made with premium ingredients, it is carefully manufactured and tested for purity. What sets it apart is what it doesn't contain: wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Doctor recommended
Effective for blood pressure
Quick shipping
Inflammation relief
Trusted brand
#TOP 7

Dr. Emil's ARGININE Plus - NO Booster Tablets

850002956245
2500mg
Dr. Emil's ARGININE Plus - NO Booster Tablets Cover
Dr. Emil's ARGININE Plus - L Arginine + L Citrulline - 2500 MG High Dose NO Booster Tablets - Nitric Oxide Supplement for Vascularity and Heart Health (Arginine AAKG and Citrulline Malate 2:1)

Dr. Emil's ARGININE Plus is a high-dose nitric oxide supplement, designed to promote vascularity and heart health. The synergistic blend of L-Arginine AAKG & HCL, along with L-Citrulline Malate, provides 2500mg of vital Nitric Oxide precursors in a convenient tablet form. Compared to other leading brands, Dr. Emil's ARGININE Plus is 50-100% stronger, with a serving size of 2500mg. The product is doctor-driven, science-backed, and free of harmful additives, hormones, and gluten.

What We Like
High-dose nitric oxide supplement
Convenient tablet form
50-100% stronger than other leading brands
Doctor-driven and science-backed
All-natural and free of harmful additives, hormones, and gluten

VITBOOST L Arginine 1500mg - Nitric Oxide Supplements

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VITBOOST L Arginine 1500mg - Nitric Oxide Supplements Cover
L Arginine Capsules with L-Citrulline 1500mg - Nitric Oxide Booster for Stamina, Muscle, Energy & Vascularity - L-Arginine and Essential Amino Supplement for Extra Strength | 30 Days Supply | 90 Count

VITBOOST L Arginine 1500mg is a premium supplement that combines Arginine HCI & Arginine Alpha-Ketoglutarate with Citrulline to provide the ultimate blend of three key Nitric Oxide ingredients that promote healthy circulation, energy levels, and blood flow to muscles. The formula is free from preservatives, additives, gluten, and sugars, ensuring an all-natural supplement that increases energy & focus without jitters.

What We Like
Promotes healthy circulation
Increases energy levels
Supports blood flow to muscles
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is L-arginine good for heart?

L-arginine isn't recommended for people who have had a recent heart attack due to concerns that the supplement might increase the risk of death. L-arginine can worsen allergies or asthma. Use the supplement with caution if you have these conditions.

2. How much L-arginine should I take for heart health?

One common dosage is 2 to 3 grams three times a day, although lower and higher doses have also been studied. The safety of long-term arginine supplement use is not clear. Ask your doctor for advice. In some cases, doctors recommend supplemental arginine.

3. Does L-arginine cause heart attacks?

It has been indicated that any defect in L-arginine metabolism such as increased levels of asymmetric dimethylarginine (ADMA), a competitive inhibitor of NO synthase, are related to endothelial dysfunction and increased risk of cardiovascular disease [5].

4. Does L-arginine prevent heart attack?

L-arginine, touted as a supplement that prevents and treats heart and circulation problems, doesn't help heart attack survivors — and it may even harm them. L-arginine provides the raw material from which the body makes nitric oxide, a tiny, transient molecule that helps relax and open blood vessels.

Editor's Notes

During our l-arginine supplement for heart health research, we found 24 l-arginine supplement for heart health products and shortlisted 8 quality products. We collected and analyzed 313,790 customer reviews through our big data system to write the l-arginine supplements for heart health list. We found that most customers choose l-arginine supplements for heart health with an average price of $19.65.

The l-arginine supplements for heart health are available for purchase. We have researched hundreds of brands and picked the top brands of l-arginine supplements for heart health, including Snap Supplements, Nature's Pure Blend, Puritan's Pride, Nature's Bounty, THORNE. The seller of top 1 product has received honest feedback from 2,008 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.