Best L-Arginine Supplements for Heart Health of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2025

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L-arginine supplements have been gaining popularity in recent years for their potential benefits in promoting heart health. L-arginine is an amino acid that helps the body produce nitric oxide, which can help improve blood flow and reduce inflammation in the arteries. Studies have shown that L-arginine supplements may help lower blood pressure, improve cholesterol levels, and reduce the risk of cardiovascular disease. These supplements are available in various forms, including pills, powders, and drinks. However, it is important to consult with a healthcare professional before taking L-arginine supplements, especially if you have a history of heart disease or are taking medication.

At a Glance: Our Top Picks

Cardio Heart Health Powder with L-Arginine Supplement Cover #TOP 1
Cardio Heart Health Powder with L-Arginine Supplement
ftb score rating icon 9.9
Dr. Emil's ARGININE Plus - NO Booster Tablets Cover #TOP 2
Dr. Emil's ARGININE Plus - NO Booster Tablets
ftb score rating icon 9.8
Pure Encapsulations L-Arginine Supplement Cover #TOP 3
Pure Encapsulations L-Arginine Supplement
ftb score rating icon 9.6

Top 10 L-Arginine Supplements for Heart Health

Cardio Heart Health Powder with L-Arginine Supplement

Cardio Heart Health Powder with L-Arginine Supplement Cover
Cardio Heart Health Powder – L-Arginine Supplement 5000mg & L-Citrulline 1000mg,16.82 oz

The Cardio Heart Health Powder is a powerful supplement that supports your muscle mass and blood flow. Its amino acid support helps your body produce Nitric Oxide, which is necessary for proper circulation. The powder is also formulated with L-Citrulline, Folic Acid, Magnesium, Selenium, and Vitamins B12, C, D, E, K, and others to support whole-body health and ensure a proper vitamin and mineral balance. L-Arginine, the key ingredient, may help ease migraines, regulate cholesterol levels, and support the immune system. The product is made in the USA and is a trusted brand that offers quality wellness products at an affordable price.

What We Like
Supports muscle mass and blood flow
Helps your body produce Nitric Oxide, which is necessary for proper circulation
Formulated with L-Citrulline, Folic Acid, Magnesium, Selenium, and Vitamins B12, C, D, E, K, and others to support whole-body health and ensure a proper vitamin and mineral balance
May help ease migraines, regulate cholesterol levels, and support the immune system
Made in the USA and is a trusted brand that offers quality wellness products at an affordable price

Dr. Emil's ARGININE Plus - NO Booster Tablets

850002956245
Dr. Emil's ARGININE Plus - NO Booster Tablets Cover
Dr. Emil's ARGININE Plus - L Arginine + L Citrulline - 2500 MG High Dose NO Booster Tablets - Nitric Oxide Supplement for Vascularity and Heart Health (Arginine AAKG and Citrulline Malate 2:1)

Dr. Emil's ARGININE Plus is a high-dose nitric oxide supplement, designed to promote vascularity and heart health. The synergistic blend of L-Arginine AAKG & HCL, along with L-Citrulline Malate, provides 2500mg of vital Nitric Oxide precursors in a convenient tablet form. Compared to other leading brands, Dr. Emil's ARGININE Plus is 50-100% stronger, with a serving size of 2500mg. The product is doctor-driven, science-backed, and free of harmful additives, hormones, and gluten.

What We Like
High-dose nitric oxide supplement
Convenient tablet form
50-100% stronger than other leading brands
Doctor-driven and science-backed
All-natural and free of harmful additives, hormones, and gluten

Pure Encapsulations L-Arginine Supplement

Pure Encapsulations L-Arginine Supplement Cover
Pure Encapsulations L-Arginine - 1,400 mg - Support Nitric Oxide Production - Heart Health & Blood Flow - Gluten Free & Non-GMO - 180 Capsules

The Pure Encapsulations L-Arginine supplement supports healthy blood flow by helping to dilate blood vessels. As an amino acid precursor of nitric oxide, it also helps with immune support, memory, and heart health. Made with premium ingredients, it is carefully manufactured and tested for purity. What sets it apart is what it doesn't contain: wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Supports healthy blood flow by dilating blood vessels
Helps with immune support, memory, and heart health
Made with premium ingredients and carefully tested for purity
Free from various allergens, artificial ingredients, and unnecessary additives
#TOP 4

BlueEarth L-Arginine 5000mg + L-Citrulline 2000mg Powder Supplement

BlueEarth Company
L-Arginine L-Citrulline Peach Lemonade
BlueEarth L-Arginine 5000mg + L-Citrulline 2000mg Powder Supplement Cover
BlueEarth Company L-Arginine 5000mg + L-Citrulline 2000mg Complex Powder Supplement - Nitric Oxide Booster - Heart Health, Blood Flow, Energy & Endurance - 30 Servings (Peach Lemonade)

BlueEarth Nitric Oxide Booster is a supplement designed to enhance heart health and circulation. With L-Arginine 5000mg and L-Citrulline, it boosts nitric oxide production, promoting healthier blood flow and supporting cardiovascular health. This supplement also supports normal circulation and blood flow, providing higher energy levels for your daily activities. Enjoy the pure and potent formula free from artificial fillers, offering a natural way to improve your health. Convenient and versatile, it dissolves in water or juice, making it easy to integrate into your daily routine.

What We Like
Heart Health & Circulation Support
Boosts Nitric Oxide Production
Convenient & Versatile Usage
#TOP 5

Dr. Emil - L Arginine

GTH-L-ARG3000-6115
Dr. Emil - L Arginine Cover
Dr. Emil - L Arginine (3150mg) Highest Capsule Dose - Nitric Oxide Supplement for Vascularity, Endurance and Heart Health (AAKG and HCL) - 90 Tablets

Dr. Emil L Arginine is a powerful nitric oxide supplement that offers several benefits for your vascularity, endurance, and heart health. With a potent blend of AAKG and Arginine HCI, this supplement enhances N.O. levels, promoting better blood flow to your organs and muscles. The 3150 mg serving size is the highest available in pill form, providing you with the same dosage as a powder but without the hassle. Compared to other leading brands, Dr. Emil L Arginine contains 2-3 times more Arginine per dose, making it more effective in promoting nitric oxide enhancement. Formulated by Dr. Emil, a medical doctor and recognized authority in the supplementation field, this product is backed by science and free of gimmicks or false promises. Made from all-natural ingredients and free of harmful additives, Dr. Emil L Arginine is a reliable choice for your health and fitness goals.

What We Like
High dosage
N.O. boosting
More effective
#TOP 6

Thorne Perfusia-SR L-Arginine Capsules

Thorne Research
Thorne Perfusia-SR L-Arginine Capsules Cover
THORNE L-Arginine Sustained Release (Formerly Perfusia-SR) - Support Heart Function, Nitric Oxide Production, and Optimal Blood Flow - 120 Capsules - 60 Servings

Sustained-release Thorne Perfusia-SR L-arginine capsules support heart health, nitric oxide production, wound healing, immune function and optimal blood flow. With twice-daily dosing, these capsules promote relaxation of arteries and support lean muscle mass and work capacity during exercise. Additionally, every Thorne product is made with the purest possible ingredients, without gluten or other major allergens, soy, dairy, shellfish, or fish. Thorne adheres to the FDA’s current Good Manufacturing Practices (cGMPs) and has the highest number of NSF Certified for Sport products which tests for more than 200 banned substances for elite athletic competitions.

What We Like
Supports heart health and optimal blood flow
Promotes relaxation of arteries and wound healing
Free from gluten, major allergens, soy, dairy, shellfish, or fish
Twice-daily dosing supports lean muscle mass and work capacity during exercise
Thorne adheres to the FDA’s current Good Manufacturing Practices (cGMPs) and has the highest number of NSF Certified for Sport products which tests for more than 200 banned substances for elite athletic competitions

Cardio 911 L-Arginine & L-Citrulline Combo

8294HS
Cardio 911 L-Arginine & L-Citrulline Combo Cover
L-arginine 5000 mg and L-citrulline 1000 mg Combo, Nitric Oxide Supplement Complex, Cardio Heart Health Powder, Mixed Berry Flavor, 16.82 Oz..

Cardio 911 Combo is a powerful nitric oxide booster that supports muscle mass and blood flow, enhancing cardiovascular health. This complex blend includes essential nutrients like folic acid, magnesium, and vitamins to promote overall well-being. With added support for circulation, stamina, and energy, this supplement is ideal for individuals of all activity levels. Made in the USA, this formula is based on Nobel Prize-winning science, ensuring quality and effectiveness for your health.

What We Like
Nitric Oxide Booster
Healthy Combo
Supports Circulation & Energy

Nature's Bounty L-Arginine Tablets

Nature's Bounty L-Arginine Tablets Cover
Nature’s Bounty L-Arginine 1000mg for Supporting Blood Flow and Vascular Function – Non-GMO, Gluten Free, 50 Tablets

Improve your heart health with Nature's Bounty L-Arginine. This supplement supports nitric oxide synthesis and circulation, which helps to promote healthy blood flow and heart function. As a protein building block, it also contributes to healthy muscles. The tablets are vegetarian and gluten-free, making them easy to incorporate into any diet. However, customers are advised to be available during delivery to avoid heat or sunlight exposure, which may damage the product.

What We Like
Supports healthy blood flow and heart function
Contributes to protein building blocks for healthy muscles
Vegetarian and gluten-free
#TOP 9

Cardio Complete - Heart Health Support Powder Supplement

Cardio Complete - Heart Health Support Powder Supplement Cover
Cardio Complete - Heart Health Support Powder Supplement - 3-in-1 Nitric Oxide Booster with 5,000 L-Arginine, 1,000mg L-Citrulline, and Hawthorn Berry

Doctor Recommended Cardio Complete is a powerful 3-in-1 Nitric Oxide Booster designed to support your heart health. With 5,000mg L-Arginine AKG and 1,000mg L-Citrulline, this supplement promotes maximum Nitric Oxide production, aiding in blood flow and overall health. Additionally, it helps in muscle building and tissue repair, enhancing stamina and workout performance. Made in the USA with natural ingredients, this product is free from allergens and GMOs, offering a delicious berry flavor for easy consumption. Trust Doctor Recommended Supplements for high-quality heart health support.

What We Like
3-in-1 Nitric Oxide Booster
Muscle Building Support
Workout Performance Enhancement
#TOP 10

Designs for Health L-Arginine 750mg Supplement

Designs for Health L-Arginine 750mg Supplement Cover
Designs for Health L-Arginine 750mg - Vegetarian Amino Acid Supplement + Nitric Oxide Precursor - Promotes Heart + Immune Health (120 Veg Capsules)

Designs for Health L-Arginine 750mg is a vegetarian amino acid supplement that promotes heart and immune health. Each capsule contains 750mg of L-Arginine, a useful amino acid for enhancing heart health, the circulatory system, and the immune system. It is also a nitric oxide precursor, which is important for blood pressure maintenance and healthy endothelial function. The product is Non-GMO, Vegetarian-Friendly, and does not contain Gluten, Dairy, or Soy. The tinted glass bottles protect nutrient viability. Over 50,000 doctors recommend Designs for Health since 1989.

What We Like
Promotes heart and immune health
Nitric oxide precursor, important for blood pressure maintenance and healthy endothelial function
Non-GMO, Vegetarian-Friendly, and free from Gluten, Dairy, or Soy
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is L-arginine good for heart?

L-arginine isn't recommended for people who have had a recent heart attack due to concerns that the supplement might increase the risk of death. L-arginine can worsen allergies or asthma. Use the supplement with caution if you have these conditions.

2. How much L-arginine should I take for heart health?

One common dosage is 2 to 3 grams three times a day, although lower and higher doses have also been studied. The safety of long-term arginine supplement use is not clear. Ask your doctor for advice. In some cases, doctors recommend supplemental arginine.

3. Does L-arginine cause heart attacks?

It has been indicated that any defect in L-arginine metabolism such as increased levels of asymmetric dimethylarginine (ADMA), a competitive inhibitor of NO synthase, are related to endothelial dysfunction and increased risk of cardiovascular disease [5].

4. Does L-arginine prevent heart attack?

L-arginine, touted as a supplement that prevents and treats heart and circulation problems, doesn't help heart attack survivors — and it may even harm them. L-arginine provides the raw material from which the body makes nitric oxide, a tiny, transient molecule that helps relax and open blood vessels.

Editor's Notes

During our l-arginine supplement for heart health research, we found 24 l-arginine supplement for heart health products and shortlisted 10 quality products. We collected and analyzed 113,324 customer reviews through our big data system to write the l-arginine supplements for heart health list. We found that most customers choose l-arginine supplements for heart health with an average price of $28.73.

The l-arginine supplements for heart health are available for purchase. We have researched hundreds of brands and picked the top brands of l-arginine supplements for heart health, including DOCTOR RECOMMENDED SUPPLEMENTS, DR. EMIL NUTRITION, Pure Encapsulations, BlueEarth Company, THORNE. The seller of top 1 product has received honest feedback from 1,748 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.