Best Protease Enzyme Supplements of 2025

Double Wood's VitaZyme Digestive Blend is a powerful 800mg blend of all 10 most essential digestive and pancreatic enzymes. It contains Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase, and Glucoamylase to break down proteins, fats, and carbohydrates. It is Non-GMO, Gluten Free, and manufactured and tested for safety in the USA. Customers have reported improved digestion, bloating relief, and better absorption of nutrition.

Get digestive support with NOW Supplements Pancreatin 10X 200mg, which contains naturally occurring protease, amylase, and lipase enzymes. It assists in the digestion of protein, fat, and carbohydrates, making it a great addition to your daily diet. This product is soy-free, nut-free, gluten-free, dairy-free, and egg-free, making it suitable for most dietary needs. NOW Supplements is a family-owned and operated company that has been in business since 1968, and their products are GMP quality assured. Customers should note that exposure to heat or sunlight can damage the product.

Vital Nutrients Pancreatic Enzymes 1000mg is a digestive enzyme supplement that supports better absorption and digestion of protein, fats, and carbohydrates. The formula contains amylase, lipase, and protease to help break down food. It is free from gluten, dairy, soy, peanut, tree nut, egg, sugar, artificial colors, and more. Vital Nutrients is committed to producing high-quality supplements and tests every ingredient and batch above the industry standard.

Doctor's Best Proteolytic Enzymes is a potent formulation containing a broad spectrum of proteolytic enzymes (proteases) to support muscle, joint, and overall tissue health. It is vegetarian, gluten-free, and Non-GMO, and comes in a 90-count veggie capsule bottle. Customers have reported positive results in terms of relief from joint and muscle pain, as well as improved gut health.

Healthy Origins Digestive Enzymes offer a powerful blend of enzymes that aid in breaking down food, enhancing your body's ability to absorb essential nutrients. This supplement includes key enzymes like amylase and lipase, which are beneficial for overall digestive health. By taking this gluten-free product, you can support your gut health effectively. Additionally, Healthy Origins ensures safety and potency through independent lab testing, giving you confidence in the quality of what you consume. Since 1996, they have been dedicated to using only active ingredients in their premium dietary supplements.

Nature's Sunshine Protease Plus is a multi-enzyme supplement that aids in digestion. It contains proteolytic enzymes, including 60,000 HUT of Protease, Beet Root Fiber, and Trace Minerals, that break down proteins into smaller, more digestible proteins. The product is formulated to enhance digestion of proteins at various levels of pH throughout the digestive tract, ranging from 3.0 to 6.0. When taken between meals, Protease Plus may help digest foreign proteins in the blood, activating Macrophages and natural killer cells. Additionally, this digestion enzyme supplement provides plant-derived trace minerals to activate enzymes and increase effectiveness.

Klaire Labs Digestive Enzymes is a powerful blend of microbial-based enzymes designed to aid in the digestion of various types of food. With enzymes targeting protein, fat, carbohydrate, sugar, and fiber, this supplement can help your body better absorb nutrients from both food and supplements. Additionally, it may provide relief from occasional gas-related discomfort such as bloating and fullness. The pH-stable formulation of these enzymes ensures that they can work effectively throughout the entire intestinal tract. Klaire Labs Digestive Enzymes is free from common allergens and artificial additives, making it a safe and natural choice for digestive support. Trust the expertise of Klaire Labs, a brand that has been developing high-quality products in collaboration with healthcare professionals since 1969.

Wonder Laboratories Enzymes provide essential support for your body’s natural responses, particularly in managing inflammation and enhancing immune health. With a blend of powerful ingredients like Bromelain and various proteolytic enzymes, this supplement aids in breaking down proteins, which is crucial for digestion and overall well-being. The inclusion of digestive enzymes like Amylase and Lipase ensures that you can effectively process food, improving your digestive experience. Manufactured in the USA by a family-owned company since 1962, you can trust the quality and formulation of these tablets for your digestive and intestinal health needs.

AVVA Pharmа Micrazym Pancreatic Enzymes is a highly effective multi-enzyme supplement that supports optimal digestion and nutrient absorption. With a high-strength formula containing lipase, protease, and amylase, these digestive enzymes break down fat molecules, proteins, and carbohydrates, allowing your body to get the most out of the foods you consume. The enteric coated micropellet technology ensures that the enzymes are protected from gastric acid, allowing them to reach the small intestine where they can be rapidly released and absorbed for prompt action. This pancreatic enzyme complex is formulated to comply with USP and European Pharmacopoeia standards, ensuring acid resistance, dissolution, and stability. In addition to supporting healthy digestion, Micrazym is also ultra-effective and economical, with one capsule replacing up to 5-15 tablets, saving you money. Order Micrazym today and enjoy the benefits of improved digestion and nutrient absorption.

NOW Plant Enzymes is a blend of enzymes that helps to support proper digestion by breaking down fats, fiber, proteins, and carbohydrates, optimizing nutrient availability in the food you eat. The product is vegan, Non-GMO, Soy Free, and Kosher certified. Moreover, the GMP quality assured certification ensures that every aspect of the NOW manufacturing process has been examined, including laboratory/testing methods for potency, stability, and product formulation. It is a plant-based enzyme supplement for people who want to maintain healthy digestion.