Best Soy-Free Enzyme Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Soy-Free Enzyme Supplements are a great option for those who are looking for digestive support without consuming soy products. These supplements are designed to assist the body in breaking down food and absorbing nutrients. They contain a blend of enzymes that work together to support healthy digestion and alleviate discomfort such as bloating, gas, and indigestion. Soy-Free Enzyme Supplements are made from high-quality, natural ingredients and are free from soy, gluten, and other common allergens. They are an excellent choice for those with food sensitivities or allergies who want to support their digestive health.

At a Glance: Our Top Picks

Essential Stacks Pure Digestive Enzymes (60 Capsules) Cover #TOP 1
Essential Stacks Pure Digestive Enzymes (60 Capsules)
ftb score rating icon 9.8
Vital Nutrients Pancreatic Enzymes Cover #TOP 2
Vital Nutrients Pancreatic Enzymes
ftb score rating icon 9.7
Protocol Enzymes-HCl Digestive Supplement Cover #TOP 3
Protocol Enzymes-HCl Digestive Supplement
ftb score rating icon 9.5

Top 10 Soy-Free Enzyme Supplements

#TOP 1

Essential Stacks Pure Digestive Enzymes (60 Capsules)

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Essential Stacks Pure Digestive Enzymes (60 Capsules) Cover
Essential Stacks Pure Digestive Enzymes (Gluten, Dairy & Soy Free) - 18 Enzymes for Digestion incl. Amylase, Lipase & Lactase - Vegetarian & Non-GMO (60 Capsules)

Essential Stacks Pure Digestive Enzymes is a multi-enzyme supplement containing 18 different digestive enzymes, including 6 enzymes for protein and gluten digestion, 1 enzyme for fat digestion, and 11 enzymes for carbohydrate digestion (including lactose, sugar, and beans). The supplement is free from gluten, wheat, dairy, milk, casein, soy, GMOs, egg, shellfish, fish, nuts, artificial colors, and flavors, making it suitable for a wide range of dietary requirements.

What We Like
Contains 18 different digestive enzymes, providing a wider range of food digestion than other enzyme supplements
Free from gluten, wheat, dairy, milk, casein, soy, GMOs, egg, shellfish, fish, nuts, artificial colors, and flavors
Includes enzymes for protein and gluten digestion, fat digestion, and carbohydrate digestion (including lactose, sugar, and beans)
#TOP 2

Vital Nutrients Pancreatic Enzymes

VNPE180
Vital Nutrients Pancreatic Enzymes Cover
Vital Nutrients Pancreatic Enzymes 1000mg (Full Strength) | Pancreatin Digestion Supplement with Protease, Amylase & Lipase | Digestive Enzymes | Gluten, Dairy, and Soy Free | 180 Capsules

Vital Pancreatic Enzymes is a high-quality digestive enzyme supplement that supports better absorption and digestion of protein, fats, and carbohydrates. With its combination of amylase, lipase, and protease, this supplement aids in breaking down food and promoting optimal digestion. By taking Vital Pancreatic Enzymes, you can experience improved digestion, which can lead to better nutrient absorption and overall digestive health. Additionally, this supplement is free from gluten, dairy, soy, and other common allergens, making it suitable for individuals with dietary restrictions. With Vital Pancreatic Enzymes, you can enjoy the convenience of a clean formula that is tested above industry standards for quality and purity.

What We Like
Supports better digestion
Free from common allergens
Tested above industry standards
#TOP 3

Protocol Enzymes-HCl Digestive Supplement

Protocol Enzymes-HCl Digestive Supplement Cover
Protocol Enzymes-HCl - Digestive Enzymes with Bromelain* - Full Spectrum of Proteases - Digestion Supplement* - Soy & Dairy Free - 120 Capsules

Protocol Enzymes-HCl is a digestive enzyme supplement designed to enhance your gastric and intestinal digestion. It features Betaine HCl, which helps create the right pH in your stomach, promoting effective digestion. The formula includes a full spectrum of proteases, such as papain, which aids in breaking down food completely, leading to better nutrient absorption. This comprehensive approach supports your overall digestive health, making it easier for you to enjoy your meals without discomfort.

What We Like
Supports digestive health
Enhances nutrient absorption
Promotes effective digestion
Natural ingredients
#TOP 4

Vital Nutrients Vegan Pancreatic Enzymes

Vital Nutrients Vegan Pancreatic Enzymes Cover
Vital Nutrients Vegan Pancreatic Enzymes | Digestive Enzymes for Women & Men | Enzymes for Digestion Support Gut Health | Relief from Gas & Bloating | Gluten, Dairy, Soy Free | 90 Capsules

Vital Nutrients Vegan Pancreatic Enzymes is a premium digestive enzyme supplement that helps your body break down food for gut health, gallbladder function, gastric emptying, and bowel regularity. It provides relief from occasional indigestion, gas, heartburn, and bloating. This clean formula is free from gluten, dairy, peanut, tree nut, soy, sesame, and egg. It is also vegan, sugar-free, and non-GMO. The supplement contains Protease, Lipase, and Amylase to support better digestion and nutrient absorption from protein, fats, and carbohydrates in one easy-to-swallow capsule taken with meals. The product is third-party tested, and the company has been manufacturing premium, practitioner-grade supplements for 30 years.

What We Like
Premium digestive enzyme supplement
Provides relief from indigestion, gas, heartburn, and bloating
Free from gluten, dairy, peanut, tree nut, soy, sesame, and egg
Contains Protease, Lipase, and Amylase to support better digestion and nutrient absorption
Third-party tested, and the company has been manufacturing premium, practitioner-grade supplements for 30 years
#TOP 5

Primax Labs Lumbrokinase Supplement

Primax Labs
LS100
Primax Labs Lumbrokinase Supplement Cover
Lumbrokinase Supplement - Lumbrokinase 40 mg per Serving (Max Activity - 800,000 units) Lumbrokinase Enzymes supplement (Similar to Nattokinase) Non GMO, Soy Free, Gluten Free (60 Capsules)

Primax Labs Lumbrokinase Supplement is a natural circulation support supplement specifically formulated to promote a healthy circulatory system. With 40mg of Lumbrokinase per capsule and a maximum activity of 800,000 units, this high potency formula ensures that you receive the optimal amount of Lumbrokinase in each serving. Manufactured in a GMP-certified, NSF-Approved facility, this supplement guarantees premium quality and purity. The easy-to-swallow capsules make it convenient for daily consumption, allowing you to fully experience the benefits of this powerful enzyme. Primax Labs stands behind the effectiveness of their supplements and offers a 100% satisfaction guarantee, making your satisfaction their top priority.

What We Like
Natural Circulation Support
High Potency Formula
Premium Quality and Purity

NOW Supplements Super Enzymes

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Beige W/Speckles
NOW Supplements Super Enzymes Cover
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

NOW Supplements Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion. Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein. It is Soy Free, Made without Gluten, Keto Friendly and GMP Quality Assured. Customers have reported that it helps with digestive issues, bloating, slow metabolism, and acid indigestion. It is easy to swallow and comes in capsule form.

What We Like
Relieves digestive issues
Improves nutrient absorption
Recommended for pancreatic insufficiency
Easy-to-swallow capsules
Supports overall digestive health
#TOP 7

Essential Stacks Betaine HCL w/ Pepsin, Ox Bile, Gentian & Ginger (120 Caps)

Essential Stacks Betaine HCL w/ Pepsin, Ox Bile, Gentian & Ginger (120 Caps) Cover
Essential Stacks Betaine HCL with Pepsin, Ox Bile, Organic Gentian & Ginger - Betaine Hydrochloride Supplement w Digestive Enzymes, Bile & Bitters - Gluten, Dairy & Soy Free (120 Capsules)

Essential Stacks Betaine HCL is a multi-enzyme dietary supplement that supports healthy digestion. It contains Betaine HCL with Pepsin to assist in breaking down protein, High Potency 1:15000 Pepsin for optimal digestion, and Ox Bile to aid in fat digestion. Additionally, it includes Organic Gentian Root to promote digestive enzymes, and Ginger to soothe the GI tract. This supplement is gluten, dairy, and soy-free.

What We Like
Supports digestion of protein and fat-rich foods like meat, fish, and eggs
High Potency 1:15000 Pepsin for optimal digestion
Includes Ox Bile for fat digestion
Organic Gentian Root promotes digestive enzymes
Ginger soothes the GI tract
#TOP 8

Vital Nutrients Pancreatin & Ox Bile Extract

VNPOB120
Vital Nutrients Pancreatin & Ox Bile Extract Cover
Vital Nutrients Pancreatin & Ox Bile Extract 500mg | Natural Digestive Enzymes for Women & Men | Supports Digestion of Protein, Fat, and Carbohydrates*| Gluten, Dairy & Soy Free | 120 Capsules

The Vital Nutrients Digestive Enzymes are designed to enhance your digestion, especially after fatty meals. With a unique blend of natural enzymes, this supplement aids in breaking down proteins, fats, and carbohydrates, promoting nutrient absorption. It also includes ox bile extract to help your body absorb fats and fat-soluble vitamins more efficiently. Plus, it's free from common allergens like gluten and dairy, ensuring a clean formula that you can trust. Just one capsule with meals can provide the digestive support you need for occasional discomfort like gas and bloating.

What We Like
Enhances digestion of proteins
Supports absorption of fats
Clean, allergen-free formula
Convenient one-capsule dosage

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia

Digestive Support Enzymes

Digestive Support Enzymes Cover
MaryRuth Organics Gluten Enzymes Capsules | Up to 2 Month Supply | Enzyme Supplement for Gut Health Support | Gluten Digestion | & Nutrient Absorption | Vegan | Gluten Free | 60 Count

This supplement aids in the digestion of gluten, ultimately supporting gluten metabolism and immune function. It helps with occasional bloating, gas and discomfort that may be associated with digesting gluten. Encapsulated in vegan capsules, you can easily incorporate these into your routine.

What We Like
Supports digestive health
May alleviate occasional bloating, gas and discomfort
Vegan and Non-GMO
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Which enzyme digests soy?

SDS‐PAGE analyses showed that hydrolysis with Alcalase, Pepsin, and Papain was most effective in the degradation of the major soybean allergens with proteolytic activities of 100%, 100%, and 95.9%, respectively.

2. How can I increase my digestive enzymes naturally?

Foods that contain natural digestive enzymes include pineapples, papayas, mangoes, honey, bananas, avocados, kefir, sauerkraut, kimchi, miso, kiwifruit and ginger. Adding any of these foods to your diet may help promote digestion and better gut health.

3. What enzymes do vegans need?

1. Pure Vegan Digestive Enzyme Complex. This Pure Vegan Digestive Enzyme Complex includes all the enzymes you'll need including amylase, protease I, protease II, lactase, lipase, cellulase, maltase, and hemicellulase.

4. What is a good digestive enzyme to take?

Best Overall: Microbiome Labs FODMATE Digestive Enzymes FODMATE's blend contains lactase (for lactose aka milk sugar), xylose isomerase (for fructose sugar), and alpha-galactosidase (for galactooligosaccharides, a type of gassy fiber).

Editor's Notes

During our soy-free enzyme supplement research, we found 24 soy-free enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 127,405 customer reviews through our big data system to write the soy-free enzyme supplements list. We found that most customers choose soy-free enzyme supplements with an average price of $26.65.

The soy-free enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of soy-free enzyme supplements, including Essential Stacks, Vital Nutrients, PROTOCOL FOR LIFE BALANCE, Primax Labs, NOW Foods. The seller of top 1 product has received honest feedback from 60 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.