Best Lipase Enzyme Supplements of 2026

BIOptimizers MassZymes Enzymes is designed to support your digestion by delivering a strong blend of enzymes that help break down proteins, fats, and carbohydrates. This can reduce bloating and improve how well your body absorbs nutrients, helping you feel lighter and more energized throughout the day. If you’re active or an athlete, it also aids in faster muscle recovery by enhancing protein breakdown, so you can bounce back quicker from workouts. Additionally, this supplement supports your gut health and immune system by easing common digestive issues like gas and indigestion, keeping your digestive tract balanced and comfortable.

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

Double Wood's VitaZyme Digestive Blend is a powerful 800mg blend of all 10 most essential digestive and pancreatic enzymes. It contains Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase, and Glucoamylase to break down proteins, fats, and carbohydrates. It is Non-GMO, Gluten Free, and manufactured and tested for safety in the USA. Customers have reported improved digestion, bloating relief, and better absorption of nutrition.

Vital Nutrients Pancreatic Enzymes 1000mg is a digestive enzyme supplement that supports better absorption and digestion of protein, fats, and carbohydrates. The formula contains amylase, lipase, and protease to help break down food. It is free from gluten, dairy, soy, peanut, tree nut, egg, sugar, artificial colors, and more. Vital Nutrients is committed to producing high-quality supplements and tests every ingredient and batch above the industry standard.

HUM Flatter Me Gut Health Supplement is an anti-bloating formula, containing 18 full-spectrum digestive enzymes, ginger, peppermint leaf, and fennel seed. It helps support digestion, soothe digestion, and support nutrient absorption. Take one capsule twice daily, before your two main meals, to reduce bloating. After only one use, 80% of users felt less bloating, and users also felt as much as 2 inches less bloating, according to a clinical study.

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

MaryRuth's Ultra Digestive Food Enzymes is a vegan supplement formulated to enable digestion, especially in those with digestive issues, amplifying nutrient absorption while reducing bloating, gas and abdominal pain. This extra strength blend of enzymes are formulated to help digest proteins, carbohydrates, fiber, fat, and lactose. It includes Protease, Amylase, Glucoamylase, Diastase, Invertase, Pectinase, Cellulase, Hemicellulase, Xylanase, Lipase, Lactase, Alpha-Galactosidase, and Beta-Glucanase. It is Non-GMO & Vegan, Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Nightshade Free, Sugar Free, and contains Maltodextrin. Customers have reported that it works great and helps reduce bloating, gas, and abdominal pain.

Enzymedica Digest Gold is a maximum strength enzyme formula that helps prevent bloating and gas. With its unique blend of 14 key enzymes, including amylase, protease, lipase, and lactase, it provides relief from occasional bloating, gas, and indigestion. By taking just one capsule before each meal, you can enjoy your favorite foods like pizza, BBQ, and pasta without feeling too full or uncomfortable afterwards. This powerful formula works quickly to break down fat, fiber, protein, and carbohydrates, making digestion more efficient. The proprietary Thera-blend enzymes work throughout the entire pH spectrum in the digestive tract, ensuring effectiveness in both acidic and alkaline environments. Enzymedica Digest Gold is also free from gluten, milk, casein, soy, egg, artificial colors, flavors, and GMOs. It is vegan, kosher, and Clean Label Project Certified, making it a trusted choice for restoring digestive confidence.

The Lemme Debloat Digestive Capsules offer a simple, all-in-one approach to keeping your gut healthy and comfortable. These capsules combine prebiotics, probiotics, and digestive enzymes to help reduce bloating, gas, and discomfort from tough-to-digest meals. The two clinically studied probiotics inside are proven to survive your stomach’s harsh environment and promote a balanced gut. Plus, five different digestive enzymes work together to break down carbs, fats, proteins, and dairy, making it easier for your body to absorb nutrients and ease digestion. This plant-based formula is designed to fit into your daily routine with no artificial additives or common allergens.

NOW Dairy Digest Complete is a vegan/vegetarian, kosher, soy-free, keto-friendly supplement that aids in the digestion of dairy products. It combines lactase, proteases, and lipases to digest lactose, dairy proteins, and fats. This multi-enzyme supplement is GMP Quality Assured and packaged in the USA by a family-owned company.