Best Papaya Enzyme Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Papaya enzyme supplements are becoming increasingly popular due to their potential health benefits. Derived from the papaya fruit, these supplements contain natural enzymes that aid in digestion and promote a healthy gut. They may also help reduce inflammation, boost the immune system, and improve skin health. Papaya enzyme supplements come in various forms, including chewable tablets and capsules, making it easy to incorporate into a daily routine. As with any supplement, it is important to speak with a healthcare professional before taking to ensure it is safe and effective for individual needs.

At a Glance: Our Top Picks

American Health Original Papaya Digestive Enzyme Chewable Tablets Cover #TOP 1
American Health Original Papaya Digestive Enzyme Chewable Tablets
ftb score rating icon 9.9
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets Cover #TOP 2
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets
ftb score rating icon 9.8
Complete Natural Products Organic Papaya Enzyme Capsules Cover #TOP 3
Complete Natural Products Organic Papaya Enzyme Capsules
ftb score rating icon 9.6

Top 10 Papaya Enzyme Supplements

American Health Original Papaya Digestive Enzyme Chewable Tablets

American Health Original Papaya Digestive Enzyme Chewable Tablets Cover
American Health Original Papaya Digestive Enzyme Chewable Tablets - Promotes Nutrient Absorption and Helps Digestion - 600 Count (200 Total Servings)

American Health Original Papaya Digestive Enzyme Chewable Tablets are a great after-meal supplement that helps promote nutrient absorption and digestion. It contains chlorophyll and peppermint to freshen breath. Customers have praised the product for its effectiveness in relieving acid reflux, bloating, and indigestion. It is vegan, gluten-free, and comes in a 600 count bottle.

What We Like
Helps promote nutrient absorption and digestion
Contains chlorophyll and peppermint to freshen breath
Effective in relieving acid reflux, bloating, and indigestion

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets Cover
American Health Super Papaya Enzyme Plus Chewable Tablets, Natural Papaya Flavor - Promotes Digestion & Nutrient Absorption, Contains Papain & Other Enzymes - 360 Count

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets are a great-tasting, vegetarian formula that helps with digestion and nutrient absorption. It contains papain and other enzymes, as well as peppermint and chlorophyll to freshen breath and reduce bad taste. Customers have found it to be helpful with inefficient digestion, nausea, upset stomach, acid reflux, and digestion. It is gluten-free, wheat-free, lactose-free, egg-free, preservative-free, yeast-free, milk-free, soy-free, grapefruit-free, sodium-free, and artificial color-free.

What We Like
Helps with digestion and nutrient absorption
Contains papain and other enzymes
Peppermint and chlorophyll freshen breath and reduce bad taste
Gluten-free, wheat-free, lactose-free, egg-free, preservative-free, yeast-free, milk-free, soy-free, grapefruit-free, sodium-free, and artificial color-free
Great-tasting, vegetarian formula

Complete Natural Products Organic Papaya Enzyme Capsules

Complete Natural Products Organic Papaya Enzyme Capsules Cover
Complete Natural Products Organic Papaya Enzymes & Papain Enzyme Capsules - 500mg 100 Pills, Organic Papaya Powder Digestive Super Fruit Capsules

Complete Natural Products Organic Papaya Enzyme Capsules are made in the USA and certified USDA Organic & OU Kosher. These veggie caps are vegan and non-GMO herbal supplements that contain natural papain enzymes from papaya. Papaya supplements are a great source of vitamins A, B, C, and K and are known as an excellent immunity booster. These capsules are high in fiber and water content, which help prevent constipation and promote a smooth bowel movement. The enzyme papain present in organic papaya powder is known to aid digestion by breaking down proteins. Therefore, a couple of capsules of papaya powder are often recommended as a home remedy for digestion-related problems and gut health.

What We Like
USDA Organic & OU Kosher certified
Vegan and non-GMO
High in fiber and water content
Contains natural papain enzymes from papaya
Great source of vitamins A, B, C, and K
#TOP 4

Carlyle Papaya Enzyme Chewable Tablets

CL4387
Carlyle Papaya Enzyme Chewable Tablets Cover
Carlyle Papaya Enzyme Chewable Tablets | Vegetarian, Non-GMO, Gluten Free Formula | Tropical Flavor

Carlyle Papaya Enzyme Chewable Tablets are a vegetarian, non-GMO, gluten-free formula with a tropical flavor. This precise blend of enzymes Protease, Amylase, Bromelain, & Lipase helps to reap the nutritional benefits of Papaya fruit. Customers have found it to be helpful for stomach upsets, heartburn, indigestion, and constipation. It is also great for rabbits!

What We Like
Vegetarian, Non-GMO, Gluten Free Formula
Tasty Tropical Chewable Tablets
Helpful for Stomach Upsets, Heartburn, Indigestion, and Constipation
#TOP 5

21st Century Papaya Enzyme Chewable Tablets

P0054
21st Century Papaya Enzyme Chewable Tablets Cover
21st Century Papaya Enzyme Chewable (100 Count), Papaya & Pineapple Digestive Enzymes for Gut Health, Tropical Flavor, Non-GMO, Gluten-Free, No Added Salt, Yeast, Artificial Flavors

21st Century Papaya Enzyme Chewable Tablets are a great way to support your digestive system. These chewable tablets are gluten-free, contain no added salt, yeast, preservatives, or artificial flavors, and are suitable for all stages. Customers have reported that the tablets taste good, work well, and are a great option for those with gastric bypass surgery.

What We Like
Gluten-free
No added salt, yeast, preservatives, or artificial flavors
Taste good and work well
#TOP 6

American Health Papaya Enzyme with Chlorophyll Chewable Tablets

American Health Papaya Enzyme with Chlorophyll Chewable Tablets Cover
American Health Papaya Enzyme with Chlorophyll Chewable Tablets - 600 Count (200 Total Servings)

American Health Papaya Enzyme with Chlorophyll Chewable Tablets is a great after meal supplement that helps promote nutrient absorption and freshens breath. It is gluten free and comes in a 600 count bottle. Customers have reported that it works great for settling their tummy and avoiding indigestion. It is also a natural papaya enzyme that can be used as a minty mouth freshener.

What We Like
Promotes nutrient absorption
Freshens breath
Gluten free
#TOP 7

American Health Super Papaya Enzyme Chewables

American Health Super Papaya Enzyme Chewables Cover
American Health Super Papaya Enzyme Plus Chewable Tablets, Natural Peppermint Flavor - Promotes Digestion & Nutrient Absorption, Contains Papain & Other Enzymes - 90 Count, 30 Total Servings

American Health Papaya Enzyme offers advanced digestive support through naturally-sourced enzymes. These chewable tablets help your body absorb nutrients effectively, making them beneficial for digesting proteins, carbohydrates, and fats. Enjoying these tasty wafers after meals can enhance your digestive comfort. Additionally, the peppermint flavor not only freshens your breath but also masks any unpleasant aftertaste. With no GMOs or artificial ingredients, this product is a convenient and health-conscious choice for anyone seeking to improve their digestion.

What We Like
Natural digestive support
Enhances nutrient absorption
Tasty and convenient
Freshens breath
Non-GMO and allergen-free
#TOP 8

NOW Papaya Enzyme with Mint and Chlorophyll, 180 Chewable Lozenges

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NOW Papaya Enzyme with Mint and Chlorophyll, 180 Chewable Lozenges Cover
NOW Foods Supplements, Papaya Enzyme with Mint and Chlorophyll, Digestive Support*, 180 Chewable Lozenges

NOW Papaya Enzyme Lozenges are a refreshing way to support protein digestion after meals. With a delicious mint flavor and 40mg of papaya per lozenge, this tablet is perfect for freshening your breath. These lozenges are Non-GMO, Soy Free, Kosher, and Keto Friendly. Additionally, the NPA A-rated GMP certification ensures that every aspect of the NOW manufacturing process has been examined, including stability, potency, and product formulation. NOW Papaya Enzyme Lozenges are packaged in the USA by a family-owned and operated company since 1968.

What We Like
Refreshing mint flavor
Supports protein digestion
Non-GMO, Soy Free, Kosher, Keto Friendly
#TOP 9

American Health Original Papaya Enzyme Chewable Tablets

American Health Original Papaya Enzyme Chewable Tablets Cover
American Health Original Papaya Enzyme Chewable Tablets - Promotes Nutrient Absorption and Helps Digestion - Gluten-Free, Vegetarian - 100 Count, 33 Total Servings, Original, 100 Count

American Health Original Papaya Enzyme Chewable Tablets are a natural digestive aid containing papain, amylase & protease enzymes to aid digestion of proteins and carbohydrates. They promote nutrient absorption, support digestive health and are convenient and delicious. These chewable tablets are ideal after any meal when looking for extra digestive support and suitable for vegans/vegetarians. They contain no gluten, yeast, wheat, milk or milk derivatives, lactose, soy, egg, grapefruit, artificial colors or sodium.

What We Like
Natural digestive aid
Promotes nutrient absorption and supports digestive health
Convenient and delicious
Ideal after any meal when looking for extra digestive support
Suitable for vegans/vegetarians and contain no artificial colors or sodium
#TOP 10

NusaPure Papaya Papain Enzyme

VB-PAPA
NusaPure Papaya Papain Enzyme Cover
NusaPure Papaya Papain Enzyme Complex 240,000 PU - 200 Veggie Caps - 100% Vegetarian, Non-GMO

NusaPure Papaya Papain Enzyme is a powerful digestive health supplement that offers 900mg of papain per serving. It is non-GMO, gluten-free, and vegan/vegetarian friendly. It is manufactured in the USA in a cGMP registered facility and is crafted with high quality, clean, and non-GMO ingredients. Customers have reported positive results in terms of digestive health support, as well as improved blood sugar levels and weight loss. However, some customers have reported feeling sick after taking the product.

What We Like
Non-GMO, gluten-free, and vegan/vegetarian friendly
Manufactured in the USA in a cGMP registered facility
Customers have reported positive results in terms of digestive health support, as well as improved blood sugar levels and weight loss
Buying Guide Image

Learn More About Purchasing the Papaya Enzyme Supplements

Benefits of Papaya Enzyme Supplements

Some potential benefits of taking papaya enzyme supplements include:

  • Improved digestion: Papain and chymopapain are both enzymes that help break down proteins in the stomach, making it easier for the body to digest food.
  • Reduced inflammation: Papaya enzymes have been shown to have anti-inflammatory effects, which can help with conditions like arthritis and inflammatory bowel disease.
  • Better absorption of nutrients: By helping to break down proteins in the stomach, papaya enzymes can improve the body's ability to absorb nutrients from food.
  • Other potential benefits: Some people also take papaya enzyme supplements for their potential benefits on the skin, immune system, and cardiovascular health.

Types of Papaya Enzyme Supplements

There are several different types of papaya enzyme supplements on the market, including:

  • Capsules: These are the most common type of papaya enzyme supplement. They typically contain powdered papaya enzymes in a gel capsule.
  • Tablets: Some papaya enzyme supplements come in tablet form, which may be easier to swallow for some people.
  • Powder: Papaya enzyme powder can be mixed with water or added to food. This is a good option for people who don't like taking capsules or tablets.

How to Choose a Papaya Enzyme Supplement

When shopping for a papaya enzyme supplement, there are a few key things to consider:

  • Quality: Look for a papaya enzyme supplement that is made from high-quality ingredients and is free from additives and fillers.
  • Dosage: Pay attention to the recommended dosage on the supplement label, and make sure to follow it closely.
  • Form: Choose a papaya enzyme supplement that comes in a form that is convenient and easy for you to take.
  • Price: Compare prices from different brands to find a papaya enzyme supplement that fits your budget.

Conclusion

Papaya enzyme supplements are a convenient and effective way to support digestive health and reduce inflammation. By considering factors like quality, dosage, form, and price, you can find the right papaya enzyme supplement for your needs.

Frequently Asked Questions (FAQs)

1. What is papaya enzyme pills good for?

Papaya enzyme pills, derived from unripe papayas, contain an enzyme called papain. This enzyme helps in breaking down proteins, aiding digestion, and allowing the gut to absorb more nutrients. It may provide relief for individuals with celiac disease, IBS, and indigestion. Additionally, papaya enzyme is known for its anti-inflammatory and antioxidant properties.

2. Is it safe to take papaya enzymes?

While papaya enzymes can be safe when used appropriately, it is important to be cautious. Large amounts of papain, found in unripe papaya fruit, can potentially damage the esophagus. When applied topically, ripe papaya fruit is generally safe for up to 10 days, but unripe papaya fruit application may be unsafe for the skin.

3. When should you take papaya enzyme?

The suggested use for papaya enzyme is to chew three tablets following a meal, one to three times daily. Alternatively, you can dissolve one or two tablets in the mouth as needed.

4. How many papaya enzyme pills should I take?

For adults, the recommended dosage is to chew three tablets of papaya enzyme following meals.

5. Is it okay to take papaya enzymes everyday?

While papaya enzymes can be beneficial, it is important not to overdo it. Consuming excessive amounts of papain, especially in supplement form, may have harmful effects, particularly on the esophagus. It is advisable to consume papaya enzymes in moderation and consult with a healthcare professional if necessary.

6. Who shouldn't take papaya enzymes?

Individuals allergic to latex or papaya should avoid using papain. Topical application of papain may cause allergic reactions, blisters, and skin irritation. It is also important to use caution if you have diabetes, hypoglycemia, or are taking medications or natural remedies that lower blood sugar, as papain may lower blood sugar levels.

Editor's Notes

During our papaya enzyme supplement research, we found 24 papaya enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 176,590 customer reviews through our big data system to write the papaya enzyme supplements list. We found that most customers choose papaya enzyme supplements with an average price of $14.08.

The papaya enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of papaya enzyme supplements, including American Health, Complete Natural Products, Carlyle, 21st Century, NOW Foods. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.