Best Tablet Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 30, 2026

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Tablet enzyme supplements are an increasingly popular way for people to improve digestion and overall gut health. These supplements are made from natural enzymes that help break down food and aid in the absorption of nutrients. They come in a variety of formulations, including those designed specifically for protein, fat, and carbohydrate digestion. Many people find that taking these supplements before meals helps reduce bloating, gas, and other digestive discomforts. Additionally, some studies suggest that enzyme supplements may have anti-inflammatory properties and could help improve immune function. Overall, tablet enzyme supplements are a convenient and effective way to support digestive health.

At a Glance: Our Top Picks

Vitamatic Lactase Enzyme 9000 FCC Cover #TOP 1
Vitamatic Lactase Enzyme 9000 FCC
ftb score rating icon 9.8
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets Cover #TOP 2
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets
ftb score rating icon 9.7
Garden of Life Dr Formulated Digestive Enzymes Cover #TOP 3
Garden of Life Dr Formulated Digestive Enzymes
ftb score rating icon 9.5

Top 5 Tablet Enzyme Supplements

Vitamatic Lactase Enzyme 9000 FCC

VMC47440
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Vitamatic Lactase Enzyme 9000 FCC Cover
Vitamatic Lactase Enzyme 9000 FCC 240 Tablets - Lactose Intolerance Relief Caplets

If you struggle with lactose intolerance, Vitamatic Lactase Supplements can be a game-changer for you. These caplets are specifically designed to aid in the digestion of dairy, allowing you to enjoy your favorite foods without discomfort. They are made without GMOs and gluten, ensuring a safer option for those with dietary restrictions. Plus, with production in the USA under strict GMP standards, you can trust the quality. Free from common allergens like soy and wheat, these tablets provide a convenient solution for lactose intolerance relief.

What We Like
High potency per tablet
Affordable large bottle
Small, easy-to-swallow pills
No aftertaste or odor
Effective lactose relief

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets Cover
American Health Products Super Papaya Enzyme Plus 360 Tablets

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets are a great-tasting, vegetarian formula that helps with digestion and nutrient absorption. It contains papain and other enzymes, as well as peppermint and chlorophyll to freshen breath and reduce bad taste. Customers have found it to be helpful with inefficient digestion, nausea, upset stomach, acid reflux, and digestion. It is gluten-free, wheat-free, lactose-free, egg-free, preservative-free, yeast-free, milk-free, soy-free, grapefruit-free, sodium-free, and artificial color-free.

What We Like
Effective for digestion
Great taste
Convenient large bottle size
Fast relief from discomfort
Helps prevent GI issues

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia
#TOP 4

LactoJoy Lactase Pills

LactoJoy Lactase Pills Cover
LactoJoy Lactase Pills 14,500 I 45 Pieces I Powerful Lactase Enzymes for Lactose Intolerance I Ultra Pure Lactase for Improved Digestion I No Silicon Dioxide, No Artificial Flavors, No Sucralose

LactoJoy Lactase Pills are a powerful solution for lactose intolerance, providing you with highly effective natural lactase enzymes to improve your digestion. With a high dosage of 14,500 FCC, you don't have to worry about calculating your lactase dosage anymore. These lactase tablets are made with natural ingredients, containing only the lactase enzyme and herbal products without any unnecessary chemical additives. The small and stylish packaging is designed to fit every situation, whether it's a business meal or a casual coffee with friends. Take these dairy pills immediately before your meal to experience fast and direct relief from abdominal discomfort, bloating, cramping, diarrhea, and other digestion issues associated with lactose intolerance. Enjoy the joy of eating without any digestive difficulties with LactoJoy Lactase Pills.

What We Like
High effectiveness
Small, easy-to-swallow pills
Convenient portable container
Higher dosage strength
#TOP 5

21st Century Papaya Enzyme Chewable Tablets

P0054
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21st Century Papaya Enzyme Chewable Tablets Cover
21st Century Papaya Enzyme Chewable (100 Count), Papaya & Pineapple Digestive Enzymes for Gut Health, Tropical Flavor, Non-GMO, Gluten-Free, No Added Salt, Artificial Flavors

21st Century Papaya Enzyme Chewable Tablets are a great way to support your digestive system. These chewable tablets are gluten-free, contain no added salt, yeast, preservatives, or artificial flavors, and are suitable for all stages. Customers have reported that the tablets taste good, work well, and are a great option for those with gastric bypass surgery.

What We Like
Gluten-free
No added salt, yeast, preservatives, or artificial flavors
Taste good and work well
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is enzyme tablet used for?

This medication contains digestive enzymes, which are natural substances needed by the body to help break down and digest food. It is used when the pancreas cannot make or does not release enough digestive enzymes into the gut to digest the food.

2. What are the benefits of taking enzyme supplements?

Proteolytic enzymes have many important functions in the body, including helping break down food for energy, and are found in certain foods and supplements. Studies suggest that they can improve digestion, decrease inflammation, ease arthritis pain and possibly reduce symptoms related to IBS.

3. What happens when you take an enzyme supplement?

Some side effects that people taking digestive enzyme supplements experience include: Allergic reactions. Interactions with medications. Abdominal pain.

4. When should I take enzymes pills?

Enzymes Should be Taken with Food In many instances, they should be taken in combination with specific foods in order to properly perform their intended function. Lactase supplements, for example, include the enzymes that digest milk sugars, so they should be taken along with dairy products.

Editor's Notes

During our tablet enzyme supplement research, we found 24 tablet enzyme supplement products and shortlisted 5 quality products. We collected and analyzed 177,755 customer reviews through our big data system to write the tablet enzyme supplements list. We found that most customers choose tablet enzyme supplements with an average price of $21.81.

The tablet enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of tablet enzyme supplements, including Vitamatic, American Health, Garden of Life, LactoJoy, 21st Century. The seller of top 1 product has received honest feedback from 8,656 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.