Best Tablet Enzyme Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Tablet enzyme supplements are an increasingly popular way for people to improve digestion and overall gut health. These supplements are made from natural enzymes that help break down food and aid in the absorption of nutrients. They come in a variety of formulations, including those designed specifically for protein, fat, and carbohydrate digestion. Many people find that taking these supplements before meals helps reduce bloating, gas, and other digestive discomforts. Additionally, some studies suggest that enzyme supplements may have anti-inflammatory properties and could help improve immune function. Overall, tablet enzyme supplements are a convenient and effective way to support digestive health.

At a Glance: Our Top Picks

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets Cover #TOP 1
American Health Super Papaya Plus Digestive Enzyme Chewable Tablets
ftb score rating icon 9.8
American Health Original Papaya Digestive Enzyme Chewable Tablets Cover #TOP 2
American Health Original Papaya Digestive Enzyme Chewable Tablets
ftb score rating icon 9.7
NOW Supplements Super Enzymes Cover #TOP 3
NOW Supplements Super Enzymes
ftb score rating icon 9.5

Top 10 Tablet Enzyme Supplements

#TOP 1

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets Cover
American Health Super Papaya Enzyme Plus Chewable Tablets, Natural Papaya Flavor - Promotes Digestion & Nutrient Absorption, Contains Papain & Other Enzymes - 360 Count

American Health Super Papaya Plus Digestive Enzyme Chewable Tablets are a great-tasting, vegetarian formula that helps with digestion and nutrient absorption. It contains papain and other enzymes, as well as peppermint and chlorophyll to freshen breath and reduce bad taste. Customers have found it to be helpful with inefficient digestion, nausea, upset stomach, acid reflux, and digestion. It is gluten-free, wheat-free, lactose-free, egg-free, preservative-free, yeast-free, milk-free, soy-free, grapefruit-free, sodium-free, and artificial color-free.

What We Like
Helps with digestion and nutrient absorption
Contains papain and other enzymes
Peppermint and chlorophyll freshen breath and reduce bad taste
Gluten-free, wheat-free, lactose-free, egg-free, preservative-free, yeast-free, milk-free, soy-free, grapefruit-free, sodium-free, and artificial color-free
Great-tasting, vegetarian formula

American Health Original Papaya Digestive Enzyme Chewable Tablets

American Health Original Papaya Digestive Enzyme Chewable Tablets Cover
American Health Original Papaya Digestive Enzyme Chewable Tablets - Promotes Nutrient Absorption and Helps Digestion - 600 Count (200 Total Servings)

American Health Original Papaya Digestive Enzyme Chewable Tablets are a great after-meal supplement that helps promote nutrient absorption and digestion. It contains chlorophyll and peppermint to freshen breath. Customers have praised the product for its effectiveness in relieving acid reflux, bloating, and indigestion. It is vegan, gluten-free, and comes in a 600 count bottle.

What We Like
Helps promote nutrient absorption and digestion
Contains chlorophyll and peppermint to freshen breath
Effective in relieving acid reflux, bloating, and indigestion

NOW Supplements Super Enzymes

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Tan W/Speckles
NOW Supplements Super Enzymes Cover
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain, Super Enzymes, 90 Tablets

NOW Supplements Super Enzymes is a multi-enzyme supplement that helps support healthy digestion by breaking down fats, carbs, and protein. Its blend of bromelain, ox bile, pancreatin, and papain optimizes nutrient availability. The easy-to-swallow tablet is GMP quality assured and packaged in the USA by a family owned and operated company since 1968.

What We Like
Comprehensive blend of enzymes supports healthy digestion
Optimizes breakdown of fats, carbohydrates, and protein
Easy-to-swallow tablet
#TOP 4

American Health Papaya Enzyme with Chlorophyll Chewable Tablets

American Health Papaya Enzyme with Chlorophyll Chewable Tablets Cover
American Health Papaya Enzyme with Chlorophyll Chewable Tablets - 600 Count (200 Total Servings)

American Health Papaya Enzyme with Chlorophyll Chewable Tablets is a great after meal supplement that helps promote nutrient absorption and freshens breath. It is gluten free and comes in a 600 count bottle. Customers have reported that it works great for settling their tummy and avoiding indigestion. It is also a natural papaya enzyme that can be used as a minty mouth freshener.

What We Like
Promotes nutrient absorption
Freshens breath
Gluten free
#TOP 5

Dr. Berg Advanced Digestive Enzymes

Dr. Berg Advanced Digestive Enzymes Cover
Dr. Berg Advanced Digestive Enzymes with Apple Cider Vinegar - Includes Digestive Health Ingredients Like Betaine Hydrochloride (HCI), Ginger Root & Peppermint Leaf - 180 Tablets

The Dr. Berg Digestive Enzymes are designed to enhance your digestive health. With 200mg of Betaine Hydrochloride and a unique blend of Organic Apple Cider Vinegar, Ginger Root, and Peppermint Leaf, these tablets support digestion when taken with meals. Manufactured in GMP-certified facilities in the US, you can trust the quality and cleanliness of each product. Dr. Berg's commitment to sourcing high-quality ingredients ensures that you receive effective support for your digestive system. Plus, with a 30-day satisfaction guarantee, you can try them risk-free and see the benefits for yourself.

What We Like
High-quality ingredients
GMP-certified manufacturing
Supports digestive health
30-day satisfaction guarantee
#TOP 6

Carlyle Papaya Enzyme Chewable Tablets

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Carlyle Papaya Enzyme Chewable Tablets Cover
Carlyle Papaya Enzyme Chewable Tablets | Vegetarian, Non-GMO, Gluten Free Formula | Tropical Flavor

Carlyle Papaya Enzyme Chewable Tablets are a vegetarian, non-GMO, gluten-free formula with a tropical flavor. This precise blend of enzymes Protease, Amylase, Bromelain, & Lipase helps to reap the nutritional benefits of Papaya fruit. Customers have found it to be helpful for stomach upsets, heartburn, indigestion, and constipation. It is also great for rabbits!

What We Like
Vegetarian, Non-GMO, Gluten Free Formula
Tasty Tropical Chewable Tablets
Helpful for Stomach Upsets, Heartburn, Indigestion, and Constipation
#TOP 7

American Health Super Papaya Enzyme Chewables

American Health Super Papaya Enzyme Chewables Cover
American Health Super Papaya Enzyme Plus Chewable Tablets, Natural Peppermint Flavor - Promotes Digestion & Nutrient Absorption, Contains Papain & Other Enzymes - 90 Count, 30 Total Servings

American Health Papaya Enzyme offers advanced digestive support through naturally-sourced enzymes. These chewable tablets help your body absorb nutrients effectively, making them beneficial for digesting proteins, carbohydrates, and fats. Enjoying these tasty wafers after meals can enhance your digestive comfort. Additionally, the peppermint flavor not only freshens your breath but also masks any unpleasant aftertaste. With no GMOs or artificial ingredients, this product is a convenient and health-conscious choice for anyone seeking to improve their digestion.

What We Like
Natural digestive support
Enhances nutrient absorption
Tasty and convenient
Freshens breath
Non-GMO and allergen-free
#TOP 8

21st Century Papaya Enzyme Chewable Tablets

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21st Century Papaya Enzyme Chewable Tablets Cover
21st Century Papaya Enzyme Chewable (100 Count), Papaya & Pineapple Digestive Enzymes for Gut Health, Tropical Flavor, Non-GMO, Gluten-Free, No Added Salt, Yeast, Artificial Flavors

21st Century Papaya Enzyme Chewable Tablets are a great way to support your digestive system. These chewable tablets are gluten-free, contain no added salt, yeast, preservatives, or artificial flavors, and are suitable for all stages. Customers have reported that the tablets taste good, work well, and are a great option for those with gastric bypass surgery.

What We Like
Gluten-free
No added salt, yeast, preservatives, or artificial flavors
Taste good and work well
#TOP 9

American Health Original Papaya Enzyme Chewable Tablets

American Health Original Papaya Enzyme Chewable Tablets Cover
American Health Original Papaya Enzyme Chewable Tablets - Promotes Nutrient Absorption and Helps Digestion - Gluten-Free, Vegetarian - 100 Count, 33 Total Servings, Original, 100 Count

American Health Original Papaya Enzyme Chewable Tablets are a natural digestive aid containing papain, amylase & protease enzymes to aid digestion of proteins and carbohydrates. They promote nutrient absorption, support digestive health and are convenient and delicious. These chewable tablets are ideal after any meal when looking for extra digestive support and suitable for vegans/vegetarians. They contain no gluten, yeast, wheat, milk or milk derivatives, lactose, soy, egg, grapefruit, artificial colors or sodium.

What We Like
Natural digestive aid
Promotes nutrient absorption and supports digestive health
Convenient and delicious
Ideal after any meal when looking for extra digestive support
Suitable for vegans/vegetarians and contain no artificial colors or sodium
#TOP 10

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is enzyme tablet used for?

This medication contains digestive enzymes, which are natural substances needed by the body to help break down and digest food. It is used when the pancreas cannot make or does not release enough digestive enzymes into the gut to digest the food.

2. What are the benefits of taking enzyme supplements?

Proteolytic enzymes have many important functions in the body, including helping break down food for energy, and are found in certain foods and supplements. Studies suggest that they can improve digestion, decrease inflammation, ease arthritis pain and possibly reduce symptoms related to IBS.

3. What happens when you take an enzyme supplement?

Some side effects that people taking digestive enzyme supplements experience include: Allergic reactions. Interactions with medications. Abdominal pain.

4. When should I take enzymes pills?

Enzymes Should be Taken with Food In many instances, they should be taken in combination with specific foods in order to properly perform their intended function. Lactase supplements, for example, include the enzymes that digest milk sugars, so they should be taken along with dairy products.

Editor's Notes

During our tablet enzyme supplement research, we found 24 tablet enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 221,405 customer reviews through our big data system to write the tablet enzyme supplements list. We found that most customers choose tablet enzyme supplements with an average price of $14.30.

The tablet enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of tablet enzyme supplements, including American Health, NOW Foods, Dr. Berg Nutritionals, Carlyle, 21st Century. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.