Best Organic Enzyme Supplements of 2025

Physician's CHOICE Enzymes is a powerful digestive health supplement designed to provide relief from mealtime discomfort. With 16 beneficial enzymes, it helps digest proteins, carbs, fruits, veggies, beans, dairy, and fats, making it suitable for all diets. The dual action approach combines digestive enzymes with prebiotics and probiotics to promote healthy digestion and gut function. The probiotics in this supplement are specially selected for their ability to survive the harsh gut environment, and the organic prebiotics fuel the growth of healthy bacteria in the gut. Crafted based on scientific research, Physician's CHOICE Enzymes are 3rd-party tested for purity and potency, ensuring a safety assured standard of quality. Take control of your digestive health with Physician's CHOICE Enzymes.

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

MaryRuth's Ultra Digestive Food Enzymes is a vegan supplement formulated to enable digestion, especially in those with digestive issues, amplifying nutrient absorption while reducing bloating, gas and abdominal pain. This extra strength blend of enzymes are formulated to help digest proteins, carbohydrates, fiber, fat, and lactose. It includes Protease, Amylase, Glucoamylase, Diastase, Invertase, Pectinase, Cellulase, Hemicellulase, Xylanase, Lipase, Lactase, Alpha-Galactosidase, and Beta-Glucanase. It is Non-GMO & Vegan, Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Nightshade Free, Sugar Free, and contains Maltodextrin. Customers have reported that it works great and helps reduce bloating, gas, and abdominal pain.

Complete Natural Products Organic Papaya Enzyme Capsules are made in the USA and certified USDA Organic & OU Kosher. These veggie caps are vegan and non-GMO herbal supplements that contain natural papain enzymes from papaya. Papaya supplements are a great source of vitamins A, B, C, and K and are known as an excellent immunity booster. These capsules are high in fiber and water content, which help prevent constipation and promote a smooth bowel movement. The enzyme papain present in organic papaya powder is known to aid digestion by breaking down proteins. Therefore, a couple of capsules of papaya powder are often recommended as a home remedy for digestion-related problems and gut health.

This supplement aids in the digestion of gluten, ultimately supporting gluten metabolism and immune function. It helps with occasional bloating, gas and discomfort that may be associated with digesting gluten. Encapsulated in vegan capsules, you can easily incorporate these into your routine.

MaryRuth Serrapeptase Capsules offer a powerful blend of enzymes designed to support your overall health. Each capsule contains a high potency of Serrapeptase, which may help improve circulation and maintain healthy tissues. This advanced enzyme complex aids in detoxifying proteins, making it easier for your body to function efficiently. Additionally, the capsules are vegan and free from common allergens, allowing you to easily incorporate them into your daily routine for enhanced immune support and balance.

Ora Organic Multi-Enzyme Supplement is a plant-based, vegan, and gluten-free dietary supplement designed to help you ease common digestive issues such as bloating and occasional constipation. It contains 15 plant-based digestive enzymes that work together to facilitate complete digestion for all diets. The supplement also includes probiotics that promote a balanced gut microbiome, and phytase, a powerhouse digestive enzyme that supports nutrient absorption. The capsules are easy to swallow, convenient to take on-the-go, and come with a 60-day satisfaction guarantee.

MaryRuth's Gut Flora Enzymes is a prebiotic, probiotic, and enzyme blend designed to support gastrointestinal health and maintain a healthy gut environment. This unique supplement provides multiple benefits, including digestive support, immune function support, and the maintenance of a balanced immune response. The enzymes in this blend contribute to overall colon health and support digestion, while the powerful probiotics and prebiotics promote a healthy microbiome and enhance the body's immune function. With easy absorption and a recommended dosage of up to 2 times daily, MaryRuth's Gut Flora Enzymes are suitable for most lifestyles. Plus, they are Non-GMO, vegan, and free from common allergens. Experience the convenience and benefits of a healthy gut with MaryRuth's Gut Flora Enzymes.

Codeage Digestive Enzymes Supplement is an all-in-one digestive enzymes solution featuring raw & vegan digestive enzymes paired with probiotics, prebiotics, fermented botanical fruits, and herbs. It contains 14 enzymes, a fermented organic botanical blend, and a probiotics blend of 4 different strains. It is made with non-GMO ingredients in the USA in a cGMP certified facility and is vegan and contains no soy, gluten, milk, egg, wheat, shellfish, color additives, or preservatives.