Best Enzyme Supplements for Constipation Relief of 2026
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Enzyme supplements are a natural and effective way to relieve constipation. These supplements contain enzymes that help break down food in the digestive system, making it easier for the body to absorb nutrients and eliminate waste. By promoting healthy digestion, enzyme supplements can help prevent constipation and other digestive issues. Some popular enzyme supplements for constipation relief include lipase, protease, and amylase. These supplements come in various forms, including capsules, powders, and chewable tablets, and can be found at most health food stores. For those looking for a safe and natural way to alleviate constipation, enzyme supplements are definitely worth considering.
At a Glance: Our Top Picks
#TOP 1
9.8
#TOP 2
9.7
#TOP 3
9.5
Top 10 Enzyme Supplements for Constipation Relief
Lovebug Toddler & Kids Probiotics
Lovebug Probiotics offers a specialized blend of 8 probiotic strains tailored for toddlers and young children aged 12 months to 4 years. The formulation aims to address digestive upsets, diarrhea, and constipation common in this age group. By providing 15 billion active cultures, including Lactobacillus GG, it supports digestive and immune health. Lovebug Probiotics is non-GMO, gluten-free, and free from artificial colors or flavors, ensuring a safe option for your child's well-being.
Physician's CHOICE Digestive Enzymes
Physician's CHOICE Enzymes is a powerful digestive health supplement designed to provide relief from mealtime discomfort. With 16 beneficial enzymes, it helps digest proteins, carbs, fruits, veggies, beans, dairy, and fats, making it suitable for all diets. The dual action approach combines digestive enzymes with prebiotics and probiotics to promote healthy digestion and gut function. The probiotics in this supplement are specially selected for their ability to survive the harsh gut environment, and the organic prebiotics fuel the growth of healthy bacteria in the gut. Crafted based on scientific research, Physician's CHOICE Enzymes are 3rd-party tested for purity and potency, ensuring a safety assured standard of quality. Take control of your digestive health with Physician's CHOICE Enzymes.
Zenwise Probiotic Digestive Multi Enzymes
Zenwise Health's Probiotic Digestive Multi Enzymes is a pre-meal plant-powered pill formulated to help women and men find relief from occasional bloating, gas, and discomfort. This advanced enzyme + prebiotic, probiotic non-GMO formula tackles hard-to-digest foods and is clinically proven to be reliably alive. It contains botanical bounty such as turmeric, ginger, green papaya, inulin, apple pectin, bladderwrack, fennel, and wakame to aid gut health and stomach comfort. Each bottle contains 180 capsules, and it is suggested to take one capsule before each meal.
NOW Supplements Super Enzymes
NOW Supplements Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion. Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein. It is Soy Free, Made without Gluten, Keto Friendly and GMP Quality Assured. Customers have reported that it helps with digestive issues, bloating, slow metabolism, and acid indigestion. It is easy to swallow and comes in capsule form.
Pure Encapsulations Digestive Enzymes Ultra
Pure Encapsulations Digestive Enzymes Ultra is a multi-enzyme supplement that supports the break down of protein, carbohydrate, fiber, and dairy*, while promoting optimal nutrient bioavailability and absorption*. The supplement contains a broad profile of digestive enzymes, providing optimal activity across a wide pH range. Pure Encapsulations uses only premium ingredients, and the product is free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.
Dr. Berg's Gallbladder Formula
Dr. Berg's Gallbladder Formula is a powerful enzymatic supplement designed to promote healthy levels of bile salts and a healthy flow of bile. It is made with state-of-the-art manufacturing facilities and high-quality ingredients sourced from domestic and international farms. It comes with a 30-day money-back guarantee and is suitable for keto dieters. Customers have reported relief from bloating, indigestion, abdominal swelling, and constipation.
Physician's CHOICE Bloat & Gas Probiotic 5-in-1
The Physician's CHOICE Bloat Relief offers a powerful 5-in-1 formula that combines probiotics, prebiotics, postbiotics, digestive enzymes, and calming herbs—all in one daily capsule. This blend helps strengthen your gut lining and improves nutrient absorption, promoting overall digestive health. It provides dual-action relief by targeting the root causes of bloating and offering fast support during mealtime gas and discomfort. Thanks to its advanced capsule technology, the ingredients release slowly for maximum effectiveness in your stomach and colon. Plus, it includes enzymes that help break down hard-to-digest foods like carbs and dairy, making it easier for you to enjoy meals without worry. Scientific research backs this product, ensuring you get a trusted, effective supplement for everyday gut support.
Enzymedica Digest Gold + ATPro
American Health Chewable Multi-Enzymes, Original Papaya
American Health Chewable Multi-Enzymes, Original Papaya supplement is designed to help with inefficient digestion and promote nutrient absorption. It is a 100% natural digestive enzyme that is useful for digestion-related issues. The vegetarian formula is great tasting and easy to consume.
Jarrow Formulas Saccharomyces Boulardii + MOS Probiotics
Frequently Asked Questions (FAQs)
1. Do digestive enzymes fix constipation?
support healthy digestion. optimize the breakdown of fats, carbohydrates, and protein. promote optimal nutrient absorption. reduce gas, bloating, indigestion, and constipation following meals.
2. Can enzyme supplements cause constipation?
Safety and Side Effects of Digestive Enzymes There are some side effects associated with taking digestive enzymes, cautions Dr. Bedford, noting that replacement enzymes may cause constipation, abdominal cramping or nausea.
3. Can low digestive enzymes cause constipation?
One of the telltale signs of exocrine pancreatic insufficiency (EPI) — a condition in which the pancreas fails to produce enough digestive enzymes — are loose, oily stools. But some people with EPI can also experience a very different symptom: intermittent constipation.
4. Why you should not take digestive enzymes?
Digestive enzyme supplements also could interact with antacids and certain diabetes medications. They may cause side effects including abdominal pain, gas and diarrhea.
During our enzyme supplement for constipation relief research, we found 24 enzyme supplement for constipation relief products and shortlisted 10 quality products. We collected and analyzed 685,448 customer reviews through our big data system to write the enzyme supplements for constipation relief list. We found that most customers choose enzyme supplements for constipation relief with an average price of $27.86.
The enzyme supplements for constipation relief are available for purchase. We have researched hundreds of brands and picked the top brands of enzyme supplements for constipation relief, including LOVEBUG, Physician's CHOICE, Zenwise Health, NOW Foods, Pure Encapsulations. The seller of top 1 product has received honest feedback from 91 consumers with an average rating of 4.9.
Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.