Best Enzyme Supplements for Cardiovascular Health of 2025

Doctor's Best Nattokinase is a vegan, non-GMO supplement derived from natto, a traditional fermented soy food popular in Japan. It contains pure nattokinase enzyme with Vitamin K2 removed, which has been shown to support a healthy circulatory system by helping to maintain normal fibrinogen levels in blood. Nattokinase can also support heart and circulatory health by promoting better blood flow. Customers should be available during delivery as exposure to heat or sunlight can damage the product.

Double Wood Nattokinase Supplement is a powerful systemic enzyme supplement that promotes cardiovascular and circulatory health. Derived from Japanese Natto, this supplement contains Nattokinase, which helps lower plasma levels of certain proteins that affect circulation. By doing so, it supports a healthy circulatory system. Research suggests that Nattokinase may also have a positive impact on cardiovascular health. With 120 capsules, each containing 200mg of Nattokinase, this two-month supply is ideal for long-term use. Manufactured and tested in the USA, this vegan-safe supplement is gluten-free and non-GMO, making it a reliable choice for those looking to support their cardiovascular and circulatory health.

Double Wood Lumbrokinase Enzymes Supplement is a high-quality supplement designed to support and maintain healthy overall function and circulation. With its proteolytic enzymes, it may help improve your cardiovascular health and blood circulation. This supplement offers a two-month supply, with each serving containing 150mg of high activity lumbrokinase. Double Wood ensures that their supplement is free from fillers, guaranteeing that you are getting only the pure lumbrokinase enzymes. Manufactured and tested in the USA, this supplement is gluten-free and non-GMO. Double Wood Lumbrokinase is your go-to choice for cardiovascular and blood circulation support.

CholestePure is a phytosterol complex that helps support healthy enzyme function, lipid metabolism, and cardiovascular health. It is a convenient source of phytosterols without the added calories from other sources. Pure Encapsulations only uses premium ingredients, and their supplements are free of common allergens, GMOs, and unnecessary additives.

The Yuve Vegan Nattokinase 2000 FU supplement is a natural blood thinner that supports cardiovascular health and aids in lowering high blood pressure. The all-natural plant-based formula includes nattokinase, a powerful enzyme extracted from traditional Japanese Natto, and is free of gluten, vitamin K, and sugar. It is suitable for vegetarians and perfect for vegans, and made in the USA in a safe facility that is both NSF and GMP certified. The small and easy to swallow pills come with a 60-day money-back guarantee.

Cardiovascular Research Serraflazyme is a multi-enzyme supplement that comes in convenient 5 mg enteric-coated tablets. These coatings help protect the enzymes from stomach acid, allowing them to reach your intestines where they can be most effective. You’ll appreciate that these tablets are free from common allergens like corn, wheat, and sugar, making them a suitable choice for those with dietary restrictions. This product can support your overall digestive health and enzyme balance, helping you feel your best every day.

These softgels contain pure NSK-SD Nattokinase extracted from non-GMO soy, which may help support cardiovascular and circulatory health. The suggested use is to take 1 softgel twice daily with water. In addition, the product is free of wheat, gluten, dairy, eggs, fish, shellfish, peanuts, tree nuts, corn, and yeast. Allergy Research Group has been committed to using pure and low allergy potential ingredients since 1979.

Serra ACTIV by Dynamic Enzymes is a powerful supplement designed to enhance your overall health. It promotes sinus and immune function, helping you feel your best throughout the year. With its focus on respiratory health, this product supports clear lungs and open airways, making breathing easier. The inclusion of acid-resistant Serrapeptase ensures that the enzymes reach their target in the body, maximizing their effectiveness. Additionally, when taken on an empty stomach, these enzymes aid in managing inflammation, contributing to your body's natural healing processes.

Natto ACTIV is a powerful supplement that promotes cardiovascular and circulatory health. It contains Nattokinase, a systemic enzyme derived from Japanese delicacy, Serrapeptase, and Bromelain. The blend supports the break down of excess fibrin and fluidity of the blood, and the body's natural inflammatory response. It is free of wheat, egg milk, soy, animal derivatives, yeast, fish or shellfish, peanuts, and tree nuts.

Dr. Mercola Lumbrokinase is a dietary supplement designed to support your cardiovascular and cognitive health. This unique blend of enzymes helps your body break down unwanted proteins, promoting a healthier inflammatory response. With its delayed-release capsules, you can ensure that the enzymes reach your intestines for optimal digestion and absorption. Additionally, this product is made with non-GMO ingredients, reflecting Dr. Mercola's commitment to quality, so you can trust what you are putting into your body. Experience balanced energy levels and improved circulation with this carefully formulated supplement.