Best Cellulase Enzyme Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Cellulase enzyme supplements are a natural dietary supplement that helps to break down cellulose, a complex carbohydrate found in plant-based foods. These supplements are designed to aid in the digestion of plant-based foods, such as fruits, vegetables, and grains, which can be difficult for some people to digest. They work by breaking down the cellulose into simpler sugars that the body can absorb and use for energy. Cellulase enzyme supplements are commonly used by individuals who follow a plant-based diet, as well as those who struggle with digestive issues or have a sensitivity to certain foods. They are available in various forms, including capsules, tablets, and powders, and can be found at health food stores and online retailers.

At a Glance: Our Top Picks

Double Wood's VitaZyme Digestive Blend Cover #TOP 1
Double Wood's VitaZyme Digestive Blend
ftb score rating icon 9.8
Klaire Labs Digestive Enzymes Cover #TOP 2
Klaire Labs Digestive Enzymes
ftb score rating icon 9.7
Balance ONE SerraDefend Biofilm Defense, Digestion - 60 Capsules Cover #TOP 3
Balance ONE SerraDefend Biofilm Defense, Digestion - 60 Capsules
ftb score rating icon 9.5

Top 10 Cellulase Enzyme Supplements

#TOP 1

Double Wood's VitaZyme Digestive Blend

Double Wood's VitaZyme Digestive Blend Cover
Digestive Enzymes - 800mg Blend of All 10 Most Essential Digestive and Pancreatic Enzymes (Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase) by Double Wood

Double Wood's VitaZyme Digestive Blend is a powerful 800mg blend of all 10 most essential digestive and pancreatic enzymes. It contains Amylase, Lipase, Bromelain, Lactase, Papain, Protease, Cellulase, Maltase, Invertase, and Glucoamylase to break down proteins, fats, and carbohydrates. It is Non-GMO, Gluten Free, and manufactured and tested for safety in the USA. Customers have reported improved digestion, bloating relief, and better absorption of nutrition.

What We Like
Effective for improving digestion
Relieves stomach issues and indigestion
Beneficial for individuals with digestive issues or on the autism spectrum
#TOP 2

Klaire Labs Digestive Enzymes

CP6241
Klaire Labs Digestive Enzymes Cover
Klaire Labs SFI Health Digestive Enzymes - Gut Health Supplements with Amylase, Protease, Lactase, Cellulase & Lipase Enzymes for Digestion - Supports Occasional Bloating & Gas (180 Capsules)

Klaire Labs Digestive Enzymes is a powerful blend of microbial-based enzymes designed to aid in the digestion of various types of food. With enzymes targeting protein, fat, carbohydrate, sugar, and fiber, this supplement can help your body better absorb nutrients from both food and supplements. Additionally, it may provide relief from occasional gas-related discomfort such as bloating and fullness. The pH-stable formulation of these enzymes ensures that they can work effectively throughout the entire intestinal tract. Klaire Labs Digestive Enzymes is free from common allergens and artificial additives, making it a safe and natural choice for digestive support. Trust the expertise of Klaire Labs, a brand that has been developing high-quality products in collaboration with healthcare professionals since 1969.

What We Like
Diverse enzyme blend
May alleviate gas-related discomfort
pH-stable formulation
#TOP 3

Balance ONE SerraDefend Biofilm Defense, Digestion - 60 Capsules

Balance ONE SerraDefend Biofilm Defense, Digestion - 60 Capsules Cover
Balance ONE SerraDefend Biofilm Defense, Digestion - Systemic and Digestive Enzymes - Serrapeptase, Nattokinase, Protease, Cellulase - 60 Capsules, 2 Month Supply

Balance ONE SerraDefend is a multi-enzyme supplement that contains powerful systemic enzymes, Serrapeptase and Nattokinase, that promote normal healing and repair in the human body. It also contains a range of digestive enzymes, and enteric coated Serrapeptase that survives passage through your stomach for maximum effectiveness. It is vegan and non-GMO, and free of all dairy, soy, nuts, wheat, gluten, preservatives, and artificial colors and flavors. The product supports healthy digestion, balanced gut flora and inhibiting biofilm production.

What We Like
Promotes normal healing and repair
Supports healthy digestion and balanced gut flora
Contains enteric coated Serrapeptase for maximum effectiveness
#TOP 4

PuraDyme Cellulase Enzyme Capsules

CEL180
PuraDyme Cellulase Enzyme Capsules Cover
PuraDyme Cellulase Individual Enzyme - 180 Capsules

PuraDyme Cellulase Supplement provides powerful digestive support with its unique blend of enzymes. Featuring 90,000 Cellulase units, this supplement aids in breaking down cellulose, making it easier for your body to digest plant-based foods. Additionally, it includes 75 Phytase units, which help in the digestion of phytic acid found in grains and seeds, enhancing nutrient absorption. This multi-enzyme formula is designed to improve overall digestive health, ensuring you get the most out of your meals. By incorporating this supplement into your routine, you can experience better digestion and increased nutrient availability.

What We Like
Supports digestive health
Enhances nutrient absorption
Breaks down plant fibers
Convenient capsule form
#TOP 5

EASTCHEM Cellulase

EASTCHEM
XW-0001
EASTCHEM Cellulase Cover
EASTCHEM Cellulase(Cellulase 2000),Cellulase Enzyme Powder,CAS NO.:9012-54-8(100g/3.52oz)

EASTCHEM Cellulase Enzyme is a multi-enzyme supplement that is ideal for various applications. Its light yellow particles are almost insoluble in ethanol, chloroform, and ether. This cellulase enzyme powder is specifically designed to make dirt easy to remove without compromising the firmness of cotton fibers. Even after repeated use, it can still soften cotton fabrics, preventing yellowing, blackening, and hardening. Unlike other washing enzymes, EASTCHEM Cellulase is not hindered by detergent ingredients surfactants, making it highly effective in washing. With an optimum temperature range of 40-60℃, it can deliver its full washing effect. EASTCHEM Cellulase is not only widely used in the detergent industry but also plays a crucial role in food, chemical, papermaking, and hemp spinning industries.

What We Like
Easy dirt removal
Softens cotton fabrics
Not hindered by detergent ingredients
#TOP 6

Digestive Enzymes Supplements - Pancreatic & Proteolytic Aid

Digestive Enzymes Supplements - Pancreatic & Proteolytic Aid Cover
Digestive Enzymes Supplements Plant Based - Pancreatic & Proteolytic Super Digestion Enzyme Supplement Pills Aid for Bloating Relief for Women & Men - Lipase, Amylase, Bromelain, Protease & Cellulase

Get digestive relief and ease bloating with this multi-enzyme supplement. The plant-based capsules aid in food digestion, absorption, and anti-bloating support. With 18 plant-based enzymes, including lipase, amylase, bromelain, protease, and cellulase, this supplement is easy to swallow and helps enhance gut health. Made in the USA, this supplement is perfect for both men and women who want to improve their digestive health.

What We Like
Provides relief for digestive issues
Aids in digestion of fat, carbs, gluten, and protein
Easy to swallow plant-based capsules
#TOP 7

Enzymedica Candidase Digestive Enzymes

20141
84 Count - Standard
Enzymedica Candidase Digestive Enzymes Cover
Enzymedica, Candidase, Digestive Enzymes for Gentle Cleansing Support, Gut Health & Digestion, 84 Count

Enzymedica Digestive Enzymes support a healthy gut microbiome, helping you maintain balanced intestinal flora for better digestive health. The dual enzyme blend of cellulase and protease offers a gentle cleansing experience, minimizing any discomfort often associated with detoxing. Thanks to the proprietary Thera-blend Technology, these enzymes work effectively across different pH levels in your body, maximizing their benefits. You only need to take two capsules on an empty stomach three times a day for optimal results, making it easy to fit into your routine.

What We Like
Supports gut health
Gentle cleansing effect
Maximized enzyme benefits
Easy dosage instructions
#TOP 8

American Standard Supplements Digestive Enzymes Plus Probiotics & Prebiotics

American Standard Supplements Digestive Enzymes Plus Probiotics & Prebiotics Cover
Digestive Enzymes Plus Probiotics & Prebiotics, 120 Veggie Capsules, For Digestion With Amylase, Bromelain, Papain, Lipase, Lactase, Protease, Papain, Cellulase, Vegan & Gluten Free, 2 Month Supply

American Standard Digestive Enzymes is a powerful supplement that combines prebiotics, probiotics, and digestive enzymes to improve your digestion health. With 1 billion probiotics, this supplement promotes the growth of good bacteria in your gut, while prebiotics provide the necessary nutrients for their survival. The 13 different enzymes in the formula help break down carbohydrates, proteins, sugars, and fats, allowing your body to absorb nutrients more efficiently. This supplement is particularly beneficial for those who have difficulty producing enough enzymes naturally. American Standard Digestive Enzymes are made with high-quality ingredients and manufactured in an FDA-registered facility, ensuring superior quality. Third-party lab testing guarantees that you are getting the best for your body. Take control of your digestive health with American Standard Digestive Enzymes.

What We Like
High potency
Combines prebiotics, probiotics, and enzymes
Improves digestion and overall health
#TOP 9

T-MILES Cellulase Enzyme 2000

T-MILES
XWSM100
100g/3.53oz
T-MILES Cellulase Enzyme 2000 Cover
T-MILES High Alkaline Cellulase REVITALENZ 2000, Cellulase Enzyme Granular Cellulase 2000,CAS NO.:9012-54-8(100g/3.53oz)

T-MILES Cellulase offers a user-friendly packaging solution with its food-grade plastic bags, making it easy for you to store and use the product while allowing for reuse. The enzyme comes in a yellowish granular form, which is visually appealing and easy to handle. With a CAS number of 9012-54-8, you can trust its quality and safety. This versatile enzyme has broad applications across various industries, including feed, textiles, and waste treatment, making it a valuable addition to your toolkit for different projects.

What We Like
Reusable packaging
Granular form for easy handling
Versatile applications
High-quality assurance
#TOP 10

Life Extension Extraordinary Enzymes Supplement

01706
Tan to Beige
Life Extension Extraordinary Enzymes Supplement Cover
Life Extension Extraordinary Enzymes, Digestive Health Support, Nutrient Absorption, Digestive enzymes, Non-GMO, 60 Capsules

Life Extension Extraordinary Enzymes is a non-GMO, gluten-free supplement with a blend of 12 clinically-studied digestive enzymes including protease, cellulase and lipase that support healthy digestion, nutrient absorption, and breakdown of hard-to-digest plant fibers. This formula provides digestive comfort by tackling hard-to-digest foods like fiber. The product is sourced using the finest raw ingredients and is manufactured in the USA.

What We Like
Provides digestive comfort
Includes potent blend of 12 clinically-studied digestive enzymes
Facilitates the breakdown of hard-to-digest plant fibers
Non-GMO and gluten-free
Manufactured in the USA
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What does cellulase supplement do?

Cellulase enzymes are very helpful for the human body. Cellulase helps control sugar blood levels, by converting cellulose into beta-glucose, preserve an balanced cholesterol level and can support in lowering cholesterol.

2. What foods produce cellulase?

In many herbivorous animals such as ruminants like cattle and sheep and hindgut fermenters like horses, cellulases are produced by symbiotic bacteria. Endogenous cellulases are produced by a few types of metazoan animals, such as some termites, snails, and earthworms....Cellulase.

3. Can you take cellulase?

Now to your question, theoretically it would be possible to take a supplemental cellulase enzyme and obtain energy from something like grass; however the fibrous structure of leaves and grass makes digesting them, even with the proper digestive enzymes, a slow process.

Editor's Notes

During our cellulase enzyme supplement research, we found 24 cellulase enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 20,253 customer reviews through our big data system to write the cellulase enzyme supplements list. We found that most customers choose cellulase enzyme supplements with an average price of $20.25.

The cellulase enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of cellulase enzyme supplements, including Double Wood Supplements, Klaire Labs, Balance ONE, PuraDyme, EASTCHEM. The seller of top 1 product has received honest feedback from 8,776 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.