Best Tablet Sinus Medicine of 2025

Sudafed Head Congestion Tablets is a non-drowsy sinus relief medicine that provides relief from sinus pain and pressure, nasal and chest congestion, and excess mucus. With its powerful formula containing phenylephrine HCl, acetaminophen, and guaifenesin, it effectively reduces congestion, relieves pain and fever, and helps to clear bronchial passageways. Whether you're suffering from hay fever, upper respiratory allergies, or the common cold, these tablets can provide temporary relief from symptoms. Say goodbye to sinus pressure, headaches, and minor aches and pains with Sudafed Head Congestion Tablets, the #1 pharmacist recommended brand among oral OTC decongestants.

GenCare Nasal Decongestant Tablets offer ultimate sinus relief by providing maximum strength nasal decongestion and sinus pressure relief from indoor or outdoor allergies or common cold symptoms. The non-drowsy formula can be taken any time of day and the bulk savings bottle is perfect for families or those who suffer from chronic congestion due to allergies or seasonal illness. The 100% satisfaction guarantee ensures ultimate convenience and customer satisfaction.

Advil Sinus Relief Medicine is a pain reliever and fever reducer with ibuprofen and phenylephrine HCl. It comes in a package of 10 coated tablets, making it easy to carry around and use whenever you need it. The ibuprofen helps to temporarily relieve fever, minor body aches and headache. The phenylephrine HCl tablets provide relief from sinus pressure, nasal congestion, and nasal swelling. This daytime or nighttime sinus medicine is suitable for adults and children aged 12 years and older. Take one of these sinus decongestant tablets every 4 hours as needed for symptoms.

Sudafed PE Sinus Pressure + Pain Relief Maximum Strength Non-Drowsy Decongestant contains 24 caplets that provide powerful relief of sinus pain, sinus pressure, nasal congestion, headaches, and fever. Each caplet contains 5mg phenylephrine HCl and 325mg acetaminophen, and can also relieve nasal congestion associated with hay fever, respiratory allergies, and the common cold. The non-drowsy decongestant promotes sinus drainage, reduces fever, and helps relieve headaches and minor aches and pain. This maximum strength formula is recommended by pharmacists for adults and children over 12 years old.

Advil Sinus Congestion and Pain is a pain reliever and fever reducer medicine that also provides sinus pressure relief, nasal congestion relief, and nasal swelling relief. Each package comes with 20 coated tablets that are portable and easy to carry around. This sinus medicine is suitable for adults and children who are 12 years and older. It contains ibuprofen 200mg and Phenylephrine HCl 10 mg, and you can take one of these tablets every 4 hours as needed for symptoms.

Introducing PhysiciansCare Sinus Decongestant, a reliable and effective solution for sinus pressure and congestion. This non-drowsy medication, manufactured by First Aid Only, offers fast relief from sinus discomfort. With its coated, easy-to-swallow tablets, PhysiciansCare Sinus Decongestant ensures a hassle-free experience. Each packet contains a single tablet, conveniently dispensed from a perforated dispenser box. Say goodbye to the inconvenience of sinus congestion, as this medication provides the same active ingredients as Sudafed PE. PhysiciansCare Sinus Decongestant is your go-to choice for quick and reliable relief from sinus pressure and congestion.

Advil Sinus Congestion and Pain Relief Medicine is a combination of ibuprofen and phenylephrine HCl that provides temporary relief from fever, minor body aches, headache, sinus pressure, nasal congestion, and nasal swelling. The coated tablets are portable and easy to carry, making it a perfect on-the-go solution. It is suitable for adults and children aged 12 years and older. This product comes with single dose packets and is HSA and FSA eligible.

Boiron SinusCalm Tablets provide effective relief from sinus discomfort caused by allergens like pollen, dust, and pet dander. These tablets are designed to alleviate sinus pressure and headaches without causing drowsiness, allowing you to go about your day without feeling sleepy. They dissolve effortlessly under your tongue, eliminating the need for water, chewing, or swallowing. Additionally, since they are non-habit forming and won’t lead to rebound congestion, you can use them with peace of mind, even if you take other medications or supplements. Plus, they qualify for HSA and FSA spending, making them a smart choice for your health.

Advil Allergy and Congestion Relief Tablets are a combination of ibuprofen, phenylephrine HCl and chlorpheniramine maleate 4 mg that help to temporarily relieve fever, body aches, headache, sinus pressure, nasal congestion, runny nose and nasal swelling. These coated tablets are easily portable, making it convenient for you to carry wherever you go. Suitable for adults and children over 12 years old.

Rite Aid Sinus Relief is designed to provide maximum strength relief from nasal congestion caused by colds, allergies, and respiratory issues. You can count on these tablets to help alleviate sinus pressure and discomfort, making it easier to breathe. The non-drowsy formula means you can take them during the day without feeling sleepy, allowing you to stay active and alert. Each tablet contains 10 mg of Phenylephrine HCI, a powerful decongestant that quickly tackles your toughest symptoms. With a trusted brand since 1962, Rite Aid aims to support your health and well-being with effective solutions.