Best Tablet Acetaminophen of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 5, 2025

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Tablet acetaminophen is a common over-the-counter pain reliever that is used to treat a variety of ailments. It is a popular choice for those who suffer from headaches, toothaches, menstrual cramps, and other minor aches and pains. This medication works by reducing the amount of pain signals that are sent to the brain, which helps to alleviate discomfort. Tablet acetaminophen is available in various strengths, and it is important to follow the recommended dosage instructions carefully. While it is generally considered safe, it is important to speak with a healthcare provider before taking any new medication.

At a Glance: Our Top Picks

Amazon Basic Care Pain Relief Tablets, 100 Count Cover #TOP 1
Amazon Basic Care Pain Relief Tablets, 100 Count
ftb score rating icon 9.9
Timely Regular Strength Pain Relief Acetaminophen Tablet Cover #TOP 2
Timely Regular Strength Pain Relief Acetaminophen Tablet
ftb score rating icon 9.8
Rite Aid Extra Strength Acetaminophen Easy Tabs Tablets, 500 mg - 100 Count Cover #TOP 3
Rite Aid Extra Strength Acetaminophen Easy Tabs Tablets, 500 mg - 100 Count
ftb score rating icon 9.6

Top 10 Tablet Acetaminophen

Amazon Basic Care Pain Relief Tablets, 100 Count

Amazon Basic Care
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Amazon Basic Care Pain Relief Tablets, 100 Count Cover
Amazon Basic Care Pain Relief, Acetaminophen Tablets 325 mg, Regular Strength, Pain Reliever and Fever Reducer, 100 Count (Packaging may vary)

Amazon Basic Care Pain Relief Tablets are an effective remedy to temporarily relieve minor aches and pains due to headache, arthritis, and menstrual cramps. It also reduces fever. The active ingredient is acetaminophen 325 mg, a potent pain reliever and fever reducer. It is suitable for both adults and children over six years old. Additionally, it is gluten-free and contains no aspirin.

What We Like
Contains acetaminophen 325mg, a strong pain reliever and fever reducer
Temporarily relieves minor aches and pains, including headache, arthritis, and menstrual cramps
Suitable for adults and children over six years old
Gluten-free and contains no aspirin
#TOP 2

Timely Regular Strength Pain Relief Acetaminophen Tablet

TIME-CAP LABS, INC.
1,000 Count
Timely Regular Strength Pain Relief Acetaminophen Tablet Cover
Timely Acetaminophen 325 MG Tablets 1000 Count - Regular Strength Pain Relief - Compared to the active ingredient in Regular Strength Tylenol - Menstrual Cramps, Fever Reducer, Minor Pain of Arthritis

Timely Regular Strength Pain Relief Acetaminophen Tablet 325 MG 1000 Count is an OTC medication that provides relief to minor aches and pains, fever, menstrual cramps, muscular aches, and premenstrual pains. It is also an affordable option that offers the same efficacy as branded acetaminophen. With 1000 tablets, it is perfect for long-term relief and an essential in every medicine cabinet.

What We Like
Relieves minor aches and pains due to various reasons, including menstrual cramps and muscular aches.
Temporarily reduces fever and relieves aches and pains caused by minor pain of arthritis.
An affordable option that provides the same quality as branded acetaminophen.

Rite Aid Extra Strength Acetaminophen Easy Tabs Tablets, 500 mg - 100 Count

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Rite Aid Extra Strength Acetaminophen Easy Tabs Tablets, 500 mg - 100 Count Cover
Rite Aid Extra Strength Acetaminophen Easy Tabs Tablets, 500 mg - 100 Count | Pain Reliever & Fever Reducer | Migraine Relief Products | Joint Pain Relief | Muscle Pain Relief | Menstrual Pain Relief

Rite Aid Acetaminophen is a trusted brand since 1962 that offers effective pain relief and fever reduction. With its extra strength formulation of 500mg, it compares to the active ingredient in Extra Strength Tylenol. The small tablets are easy to swallow, thanks to their sweet coating, making it convenient for use at home or on-the-go. Each gelcap contains 500mg of acetaminophen without any aspirin, making it ideal for those seeking arthritis pain relief, back pain relief, joint pain relief, or muscle pain relief. Rite Aid Acetaminophen is your go-to solution for minor headaches, migraines, muscular and body aches, and pains associated with arthritis and joint pain.

What We Like
Extra strength formulation
Easy to swallow tablets
No aspirin
#TOP 4

Tylenol Extra Strength Coated Tablets, 100 ct

Tylenol Extra Strength Coated Tablets, 100 ct Cover
Tylenol Extra Strength Coated Tablets, Acetaminophen Adult Pain Relief & Fever Reducer, 100 ct

Tylenol Extra Strength Coated Tablets contain 500mg of acetaminophen per tablet that work quickly to relieve minor aches and pains due to headaches, cold, toothache, arthritis, and menstrual cramps. As a recommended brand by doctors, Tylenol provides fast and strong relief so you can get back to your daily activities.

What We Like
Effective relief from minor aches and pains
Contains 500mg of acetaminophen per tablet
Fast-acting

Amazon Basic Care Acetaminophen 650 mg

Amazon Basic Care
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Amazon Basic Care Acetaminophen 650 mg Cover
Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, Arthritis Pain, 400 Count

Amazon Acetaminophen Pain Relief offers effective support for those dealing with minor arthritis pain. Each tablet contains 650 mg of acetaminophen, which is designed to relieve pain and reduce fever. This product is particularly useful for alleviating various discomforts, such as muscular aches, backaches, and menstrual cramps. Additionally, the extended-release formula ensures that you experience longer-lasting relief without the worry of taking multiple doses. Plus, it’s gluten-free and aspirin-free, making it a safe choice for many users. The child-resistant cap adds an extra layer of safety for households with children.

What We Like
Effective pain relief
Extended-release formula
Aspirin-free and gluten-free
Child-resistant cap
#TOP 6

Tylenol Regular Strength Tablets

300450496607
Tylenol Regular Strength Tablets Cover
Tylenol Regular Strength Tablets, Acetaminophen Pain Reliever & Fever Reducer, 100 ct

Tylenol Pain Reliever is a 100-count bottle of acetaminophen tablets that provides temporary relief of minor aches and pains, as well as helps reduce fever. Each tablet contains 325 mg of acetaminophen, which effectively relieves pain and has a great safety profile when used as directed. This pain reliever can be used by adults and children 6 years and older. It is ideal for alleviating common pain symptoms like headache, backache, toothache, menstrual cramps, and pain caused by the common cold. With Tylenol Pain Reliever, you can experience effective relief and get back to feeling your best. It is the #1 doctor recommended brand for pain relief and fever reduction.

What We Like
Temporary relief of aches and pains
Reduces fever
Excellent safety profile
#TOP 7

Timely Acetaminophen 325 MG Tablets

TIME-CAP LABS, INC.
Timely Acetaminophen 325 MG Tablets Cover
Timely Acetaminophen 325 MG Tablets 100 Count - Regular Strength Pain Relief - Compared to the active ingredient in Regular Strength Tylenol - Menstrual Cramps, Fever Reducer, Minor Pain of Arthritis

Timely Acetaminophen Tablets are designed to help you manage minor aches and pains effectively. Whether you're struggling with a headache, backache, or menstrual cramps, these tablets provide quick relief when you need it most. If you're dealing with a fever, this medication can help lower your temperature while alleviating discomfort. With 100 tablets in each bottle, you can ensure your family is well-prepared for any pain relief needs. Simply follow the dosage instructions, and you can experience the convenience of being pain-free with this high-quality, over-the-counter solution.

What We Like
Effective pain relief
Fever reduction
Convenient 100-count supply
Easy to use
#TOP 8

Amazon Basic Care Acetaminophen Extended-Release Tablets

Amazon Basic Care
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Amazon Basic Care Acetaminophen Extended-Release Tablets Cover
Amazon Basic Care Acetaminophen Extended-Release Tablets, 650 mg, 100 Count (Packaging may vary)

Amazon Basic Care Acetaminophen Extended-Release Tablets, also known as Amazon Acetaminophen Tablets, are a safe and effective pain reliever and fever reducer. With its active ingredient, acetaminophen 650 mg, it provides up to 8 hours of relief, helping you get through the day. This medication is great for minor muscle aches and pains, backache, arthritis pain, toothache, premenstrual and menstrual cramps, headache, the common cold, and fever. It's suitable for adults and children 12 years and older. The child-resistant push and turn cap ensures safety. Plus, it's gluten-free and contains no aspirin. Take advantage of the convenience and reliability of Amazon Basic Care Acetaminophen Extended-Release Tablets for all your pain relief needs.

What We Like
8 hours relief
Safe and effective
Gluten-free
#TOP 9

GeriCare Extra Strength Pain Relief Acetaminophen Tablets

357896201012-1
GeriCare Extra Strength Pain Relief Acetaminophen Tablets Cover
GeriCare Extra Strength Acetaminophen Pain Relief Fever Reducer Tablets, Strength 500mg Tablet | Joint, Muscle, Arthritis, Back Pain Relief 100 Count (Pack of 1)

GeriCare Extra Strength Pain Relief Acetaminophen Tablets are non-aspirin pain relievers that can help alleviate various types of pain. They are acetaminophen-based and come in a bottle of 100 tablets. The product is manufactured by Geri-Care and has a product code of 357896221010.

What We Like
Effective in relieving pain
Acetaminophen-based
Comes in a bottle of 100 tablets

Tylenol 8 Hour Arthritis Pain Relief Caplets, 100 ct

ASINPRILAK2754
100 Count
Tylenol 8 Hour Arthritis Pain Relief Caplets, 100 ct Cover
Tylenol 8 Hour Arthritis Pain Tablets with Acetaminophen for Joint Pain, 100 ct

Get fast-acting and temporary relief from minor arthritis and joint pain with Tylenol 8 Hour Arthritis Pain Extended-Release Caplets. With two effective layers of pain relief, each tablet contains 650mg of acetaminophen that provides relief for up to 8 hours. You can use it to alleviate minor aches, fever, and pains caused by arthritis or other conditions. This oral pain reliever has an excellent safety profile and can be used by adults 18 years and older. Tylenol is the #1 doctor recommended OTC brand for arthritis pain relief and pain and fever reduction.

What We Like
Fast-acting and temporary relief for minor arthritis and joint pain
Two effective layers of pain relief in each tablet
Relieves minor aches, fever, and pains caused by arthritis or other conditions
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is the use of acetaminophen tablets?

Acetaminophen is used to relieve mild to moderate pain from headaches, muscle aches, menstrual periods, colds and sore throats, toothaches, backaches, and reactions to vaccinations (shots), and to reduce fever.

2. Is acetaminophen & paracetamol the same?

Acetaminophen is the United States adopted name,4 and in the United States the substance is always and only called acetaminophen. Paracetamol is the recommended international non-proprietary name,4 the British approved name,4 and the name used for the substance throughout the world outside the United States.

3. Why is paracetamol called acetaminophen?

It is used in many drugs that treat the flu and colds. The words acetaminophen and paracetamol both come from the names of the chemicals used in the compound: N-acetyl-para-aminophenol and para-acetyl-amino-phenol. Sometimes, it is shortened to APAP, for N-acetyl-para-aminophenol.

4. What is the generic name of acetaminophen?

Acetaminophen (Tylenol) is the brand name and acetaminophen is the generic name. They both work the same.

Editor's Notes

During our tablet acetaminophen research, we found 24 tablet acetaminophen products and shortlisted 10 quality products. We collected and analyzed 274,807 customer reviews through our big data system to write the tablet acetaminophen list. We found that most customers choose tablet acetaminophen with an average price of $10.55.

The tablet acetaminophen are available for purchase. We have researched hundreds of brands and picked the top brands of tablet acetaminophen, including TIME-CAP LABS, INC., Rite Aid, TENA, GeriCare, Tylenol. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.