Best Vitamin B12 Supplements for Cardiovascular Health of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 8, 2025

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Vitamin B12 supplements are often recommended for cardiovascular health. This essential vitamin plays a crucial role in the production of red blood cells, which carry oxygen throughout the body. A deficiency in vitamin B12 can lead to anemia, which can cause fatigue and weakness. Additionally, studies have shown that low levels of vitamin B12 may be linked to an increased risk of heart disease. By supplementing with vitamin B12, individuals can help support their cardiovascular health and overall well-being. There are a variety of vitamin B12 supplements available on the market, including capsules, tablets, and gummies. It is important to speak with a healthcare provider before starting any new supplement regimen.

At a Glance: Our Top Picks

Nature's Bounty Vitamin B12 Sublingual Liquid Cover #TOP 1
Nature's Bounty Vitamin B12 Sublingual Liquid
ftb score rating icon 9.9
MegaFood Vegan B12 Daily Multivitamin Supplement Cover #TOP 2
MegaFood Vegan B12 Daily Multivitamin Supplement
ftb score rating icon 9.8
Carlson - Tri-B, Vitamin B Complex, 120 Tablets Cover #TOP 3
Carlson - Tri-B, Vitamin B Complex, 120 Tablets
ftb score rating icon 9.6

Top 10 Vitamin B12 Supplements for Cardiovascular Health

Nature's Bounty Vitamin B12 Sublingual Liquid

18187
White
2 Fl Oz (Pack of 1)
Nature's Bounty Vitamin B12 Sublingual Liquid Cover
Nature's Bounty Vitamin B12 5000 Mcg Sublingual Liquid, Cardiovascular Health & Cellular Energy Support, 2 Fl Oz (1 Count)

Nature's Bounty Vitamin B12 Sublingual Liquid is an easy-to-take supplement that supports cellular energy and heart health. It contains 5000 mcg of Vitamin B12 per serving, which helps convert food into energy that your body needs. Additionally, Vitamin B12 is important for maintaining healthy nerve cells and supporting the cardiovascular and circulatory systems. This gluten-free and sugar-free liquid has a natural berry flavor and is suitable for vegetarians. Nature's Bounty has nearly 50 years of experience in producing high-quality vitamins and nutritional supplements.

What We Like
Supports cellular energy and heart health
Easy-to-take sublingual liquid with natural berry flavor
Gluten-free, sugar-free, and suitable for vegetarians

MegaFood Vegan B12 Daily Multivitamin Supplement

MGF-077
MegaFood Vegan B12 Daily Multivitamin Supplement Cover
MegaFood Vegan Vitamin B12, Vitamin B Supplement with Vitamin B6, B12 Vitamins, and Folic Acid, Supports Cellular Energy Production, Nervous System Health & Cardiovascular Function - 30 Tablets

The MegaFood Vegan B12 Daily Multivitamin Supplement is a plant-based, vegan B12 supplement that helps support healthy blood cell formation and optimized performance. It also contains vitamin B6 and folic acid to help support cellular energy in the body and nervous system function. This supplement is convenient and easy to swallow, suitable for vegan and vegetarian diets, and can be taken any time of day, even on an empty stomach. The MegaFood Vegan B12 Daily Multivitamin Supplement is Non-GMO Project Verified, free of gluten, dairy, and soy, and is made with real food and added nutrients.

What We Like
Plant-based, vegan B12 helps support healthy blood cell formation and optimized performance
Contains vitamin B6 and folic acid to help support cellular energy in the body and nervous system function
Convenient and easy to swallow, suitable for vegan and vegetarian diets, and can be taken any time of day, even on an empty stomach
Non-GMO Project Verified, free of gluten, dairy, and soy
Made with real food and added nutrients

Carlson - Tri-B, Vitamin B Complex, 120 Tablets

2001
Carlson - Tri-B, Vitamin B Complex, 120 Tablets Cover
Carlson - Tri-B, Vitamin B Complex, 25 mg Vitamin B-6, 400 mcg Vitamin B-12, Folic Acid Energy Pills, Promote Cardiovascular Health, B Complex Vitamins, B12 Supplement, B Vitamin Complex, 120 Tablets

Carlson Tri-B Vitamin B Complex is a high-quality supplement that promotes cardiovascular health and provides essential B vitamins. With 25 mg of Vitamin B-6, 400 mcg of Vitamin B-12, and folic acid, this supplement is designed to support your overall well-being. The first feature is that the product is shipped in accordance with manufacturers' recommendations, ensuring its quality even during the summer months. The second feature is the convenient packaging of 120 tablets, providing a long-lasting supply. The third feature is the B vitamin complex, which plays a crucial role in energy production, supporting your daily activities. Lastly, this supplement is a great addition to your routine if you're looking for a B12 supplement. Try Carlson Tri-B Vitamin B Complex and experience the benefits of these essential vitamins.

What We Like
Promotes cardiovascular health
Convenient packaging with 120 tablets
Supports energy production
#TOP 4

Bio-Tech Pharmacal B12-Methyl Capsules

Bio-Tech Pharmacal
455A
Bio-Tech Pharmacal B12-Methyl Capsules Cover
Vitamin B12 Methylcobalamin Methyl cobalamin Dietary supplement for red blood cell formation dna synthesis cardiovascular health homocysteine metabolism cognitive function restful sleep - 100 Capsules

Bio-Tech B12-Methyl Capsules are designed to support your cognitive function, heart health, and restful sleep. This supplement aids in maintaining cardiovascular and nervous system health. With 1000 mcg of methylcobalamin, it helps in energy production, red blood cell formation, and DNA synthesis. Ideal for vegetarians and those with digestive issues, it balances homocysteine metabolism. Free of common allergens, it offers you a convenient way to get your daily dose of essential vitamin B12.

What We Like
Cognitive support
Heart health
Restful sleep

Nature's Bounty Vitamin B12, 1000mcg, 200 Ct

Nature's Bounty Vitamin B12, 1000mcg, 200 Ct Cover
Nature's Bounty Vitamin B12, Supports Energy Metabolism, Tablets, 1000mcg, 200 Ct

Nature's Bounty B12 Tablets are a product of nearly 50 years of dedication to quality, consistency, and scientific research to make vitamins and nutritional supplements of unrivaled excellence. These tablets support cellular energy health by aiding in the conversion of food into cellular energy. They also support cardiovascular health and help maintain healthy nerves. The tablets are easy to swallow as they are coated, making them more convenient for users.

What We Like
Supports energy metabolism
Helps with red blood cell formation
Crucial for healthy pregnancies
Prevents osteoporosis
Great value
#TOP 6

Nature's Bounty Vitamin B12 500mcg Tablets, 100 Ct

Nature's Bounty Vitamin B12 500mcg Tablets, 100 Ct Cover
Nature's Bounty Vitamin B12, Supports Energy Metabolism and Nervous System Health, 500mcg, 100 Quick Dissolve Tablets

Nature's Bounty B12 Tablets are designed to support energy metabolism, heart and nervous system health. With 500mcg of Vitamin B12 per tablet, they help convert food into energy, supporting your body's daily energy needs. Vitamin B12 is also known for its benefits to the cardiovascular and circulatory systems. In addition, B12 is essential for maintaining healthy nerve cells, supporting your overall nervous system health. Nature's Bounty B12 Tablets are made with purity in mind, suitable for vegetarians, and free from GMO, gluten, and sugar.

What We Like
Supports energy metabolism
Benefits cardiovascular health
Supports nervous system health
Pure and suitable for vegetarians
#TOP 7

MegaFood Methyl B12 Supplement for Heart Health

10333
MegaFood Methyl B12 Supplement for Heart Health Cover
MegaFood Methyl B12 - Vegan - Includes Methyl Folate, Vitamin B12 & B6 - Supports Cellular Energy Production, Nervous System Health & Cardiovascular Function - 90 Tablets

MegaFood Methyl B12 is a heart health supplement containing active B vitamins that supports heart and blood health. The mini-tablet is easy to swallow and includes methylated vitamin B12 and folate, as well as an active form of B6, to maintain healthy homocysteine levels. It can be taken at any time of day, even on an empty stomach, and includes broccoli, beetroot, brown rice, and added nutrients. The supplement is Non-GMO Project Verified, gluten-free, dairy-free, soy-free, Certified B Corp, and Certified Kosher. MegaFood works with trusted farm partners committed to natural and regenerative agriculture.

What We Like
Supports heart and blood health
Made with active B vitamins, including methylated vitamin B12 and folate, and an active form of B6
Can be taken at any time of day, even on an empty stomach
Non-GMO Project Verified, gluten-free, dairy-free, soy-free, Certified B Corp, and Certified Kosher
Contains real food and added nutrients, and is made with trusted farm partners committed to natural and regenerative agriculture
#TOP 8

Nature's Bounty Vitamin B12, 40 Tablets

Nature's Bounty Vitamin B12, 40 Tablets Cover
Vitamin B12 by Nature's Bounty, Quick Dissolve Vitamin Supplement, Supports Energy Metabolism and Nervous System Health, 5000mcg, 40 Tablets

Nature's Bounty B12 is a vitamin supplement that supports energy metabolism and nervous system health. The 40-count quick dissolve tablets help the body convert food into fuel, which is used to produce cellular energy. This vitamin is commonly used to support the health of the cardiovascular and circulatory systems, and it is an important vitamin for maintaining healthy nerve cells. Nature's Bounty is committed to safety and purity in all their supplements, making these quick-dissolve Vitamin B12 tablets suitable for vegetarians. They are gluten- and sugar-free, and contain no artificial colors or sweeteners. With nearly 50 years of dedication to quality, consistency, and scientific research, Nature's Bounty Vitamin B12 tablets are a product of unrivaled excellence.

What We Like
Quick dissolve tablets
Supports energy metabolism
Supports nervous system health
Gluten and sugar-free
Suitable for vegetarians
#TOP 9

Jarrow Formulas Methyl B-12 & Methyl Folate Tablets

Jarrow Formulas Methyl B-12 & Methyl Folate Tablets Cover
Jarrow Formulas Ultra Strength Methyl B-12 5000 mcg & Methyl Folate 800 mcg + P-5-P, Dietary Supplement for Cellular Energy Metabolism and Cardiovascular Support, 60 Chewable Tablets, 60 Day Supply

Jarrow Formulas Methyl B-12 & Methyl Folate Tablets are cherry-flavored chewable tablets that provide bioactive B vitamins, including methylcobalamin (methyl B-12) & methyl folate, coenzyme form of vitamin B6, and P5P. It supports cellular energy metabolism production, brain function, DNA & neurotransmitter synthesis, and amino acid metabolism. Moreover, this unique combination of vitamins helps recycle homocysteine to methionine for cardiovascular health. These convenient tablets are gluten-free, dairy-free, and contain no egg, fish/shellfish, or peanuts/tree nuts

What We Like
Provides bioactive B vitamins, including methylcobalamin (methyl B-12) & methyl folate, coenzyme form of vitamin B6, and P5P.
Supports cellular energy metabolism production, brain function, DNA & neurotransmitter synthesis, and amino acid metabolism.
Recycles homocysteine to methionine for cardiovascular health.
Convenient and cherry-flavored chewable tablets.
Gluten-free, dairy-free, and contains no egg, fish/shellfish, or peanuts/tree nuts.

Life Extension Vitamin B12 Lozenges

01536
Pink Red
Life Extension Vitamin B12 Lozenges Cover
Life Extension Vitamin B12 Methylcobalamin, Nerve Health Supplement, Cognitive Support, Energy Vitamin, methylcobalamin B12, 1 mg, Quick-Dissolving, Vegetarian, 60 lozenges

Life Extension Vitamin B12 Lozenges are a convenient way to support brain, heart, and nerve health. These vegetarian lozenges dissolve in your mouth and contain methylcobalamin, an active form of vitamin B12 that supports cognitive function. They also help maintain healthy homocysteine levels, essential to heart and nerve health, and red blood cell growth, which carries oxygen throughout the body. The product is non-GMO, gluten-free, and sourced from high-quality raw ingredients.

What We Like
Convenient way to support brain, heart, and nerve health
Methylcobalamin helps maintain healthy homocysteine levels
Essential for red blood cell growth and oxygen transport
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is vitamin B-12 good for heart health?

May Improve Heart Health by Decreasing Homocysteine If you're significantly deficient in vitamin B12, your homocysteine levels become elevated. Studies have shown that vitamin B12 helps decrease homocysteine levels, which may reduce your risk of heart disease ( 20 , 21 , 22 ).

2. Can a B12 supplement be harmful?

When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.

3. Is vitamin B complex good for your heart?

Taking folic acid or B-complex vitamins may reduce risk for heart attack, stroke, or death due to heart disease, but most supplements do not appear to provide any benefit.

Editor's Notes

During our vitamin b12 supplement for cardiovascular health research, we found 24 vitamin b12 supplement for cardiovascular health products and shortlisted 10 quality products. We collected and analyzed 459,554 customer reviews through our big data system to write the vitamin b12 supplements for cardiovascular health list. We found that most customers choose vitamin b12 supplements for cardiovascular health with an average price of $13.11.

The vitamin b12 supplements for cardiovascular health are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b12 supplements for cardiovascular health, including Nature's Bounty, MegaFood, Carlson, Bio-Tech Pharmacal, Jarrow Formulas. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.