Best Vitamin D Supplements for Cardiovascular Health of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 20, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Vitamin D supplements have been gaining popularity in recent years due to their potential benefits for cardiovascular health. Research has shown that low levels of vitamin D are associated with an increased risk of heart disease and stroke. Vitamin D plays a role in regulating blood pressure, reducing inflammation, and improving insulin sensitivity, all of which are important factors in maintaining a healthy cardiovascular system. While vitamin D can be obtained through sunlight exposure and certain foods, many people may not get enough from these sources and may benefit from taking a supplement. It is important to talk to a healthcare provider before starting any new supplement regimen.

At a Glance: Our Top Picks

Thorne Vitamin D3-5000IU Supplement - 60 Capsules Cover #TOP 1
Thorne Vitamin D3-5000IU Supplement - 60 Capsules
ftb score rating icon 9.9
Sports Research Vegan Vitamin D3+K2 with Organic Coconut Oil - 60 Softgels Cover #TOP 2
Sports Research Vegan Vitamin D3+K2 with Organic Coconut Oil - 60 Softgels
ftb score rating icon 9.8
Thorne Vitamin D-1000 Cover #TOP 3
Thorne Vitamin D-1000
ftb score rating icon 9.6

Top 6 Vitamin D Supplements for Cardiovascular Health

Thorne Vitamin D3-5000IU Supplement - 60 Capsules

D138
Thorne Vitamin D3-5000IU Supplement - 60 Capsules Cover
THORNE - Vitamin D-5000 - Vitamin D3 Supplement - Support Healthy Bones, Teeth, Muscles, Cardiovascular & Immune Function* - NSF Certified for Sport - Gluten-Free, Soy-Free - 60 Servings

Thorne Vitamin D3-5000IU Supplement - 60 Capsules is the perfect vitamin D supplement for you. Vitamin D3 supports healthy bones, teeth, muscles, cardiovascular health, and immune function. It is more potent and better absorbed than vitamin D2. This supplement is NSF Certified for Sport and free from gluten, eggs, tree nuts, peanuts, dairy, soy, fish, or shellfish. Thorne is trusted by 100+ pro teams and is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams.

What We Like
High potency (5,000 IU)
Pure formula, no fillers
Easy to swallow capsules
Noticeable energy and mood improvement
Trusted brand with NSF certification

Sports Research Vegan Vitamin D3+K2 with Organic Coconut Oil - 60 Softgels

FG218
No Color
Sports Research Vegan Vitamin D3+K2 with Organic Coconut Oil - 60 Softgels Cover
Sports Research® Vitamin D3 + K2 w/ Coconut Oil - Vegan Vitamin D 5000iu & Mk7 Vitamin K 100mcg for Bone & Immune Support - Vegan Certified · Non-GMO · Soy Free - 60 Softgels

Sports Research Vegan Vitamin D3+K2 with Organic Coconut Oil combines two essential vitamins to support bone and immune health. The new softgel shell, containing added turmeric root powder, helps protect the active ingredients inside against UV light. Vitamin D3 helps maintain strong bones and supports a healthy immune system, while Vitamin K2 ensures that calcium gets deposited in your bones where it's needed and protects arteries from calcification. This vegan formula uses patented plant-based forms of both vitamins and is free of soy, gluten, gelatin, and carrageenan. The easy-to-swallow softgels are of superior quality, third-party tested, and manufactured in cGMP compliant facilities in the U.S.

What We Like
Easy to swallow softgels
Vegan and clean ingredients
No aftertaste or odor
Combines D3 and K2
Trusted, reliable brand

Thorne Vitamin D-1000

D128
Thorne Vitamin D-1000 Cover
THORNE - Vitamin D3 Supplement - Supports Healthy Bones, Teeth, Muscles, Cardiovascular & Immune Function* - Gluten, Dairy & Soy-Free - 1,000 IU - 90 Servings

Thorne D-1000 is a vitamin D3 supplement that supports healthy bones, teeth, muscles, cardiovascular health, and immune function. Vitamin D3 is known for its optimal absorption compared to vitamin D2, making it more potent and easily absorbed by the body. With Thorne's vitamin D supplements, you can enjoy the benefits without worrying about lactose or preservatives, as these capsules are free from both. Additionally, Thorne D-1000 is a gluten-free, dairy-free, soy-free supplement that doesn't contain eggs, tree nuts, peanuts, fish, or shellfish. With its trusted reputation and collaborations with Mayo Clinic and U.S. Olympic Teams, Thorne is a brand you can rely on for your wellness needs.

What We Like
High absorbability
Gluten-free, dairy-free, and soy-free
Small and easy-to-consume capsules
Effective in raising vitamin D levels
Trusted brand

Pure Encapsulations Vitamin D3 125 mcg (5,000 IU)

Pure Encapsulations Vitamin D3 125 mcg (5,000 IU) Cover
Pure Encapsulations Vitamin D3 125 mcg (5,000 IU) - Supplement to Support Bone, Joint, Breast, Heart, Colon, and Immune Health* - with Vitamin D - 120 Capsules

Looking for a supplement to support your bone, joint, breast, heart, colon, and immune health? Consider Pure Encapsulations Vitamin D3 125 mcg (5,000 IU). This gluten-free supplement promotes optimal bone health by supporting calcium absorption, helps maintain healthy blood vessel function, and supports immune cell activity. Pure Encapsulations' products are made with only premium ingredients, free from unnecessary additives, and carefully manufactured and tested for potency and purity.

What We Like
Promotes optimal bone health by supporting calcium absorption and retention.
Supports immune cell activity by binding to receptors on immune cells, including lymphocytes and macrophages.
Free from unnecessary additives such as artificial colors, flavors, sweeteners, and preservatives, as well as common allergens such as wheat, eggs, tree nuts, and peanuts.

Thorne Vitamin D-10,000 Supplement - 60 Capsules

D148
Thorne Vitamin D-10,000 Supplement - 60 Capsules Cover
THORNE - Vitamin D3 Supplement - Supports Healthy Bones, Teeth, Muscles, Cardiovascular & Immune Function* - Gluten, Dairy & Soy-Free - 10,000 IU - 60 Servings

Thorne Vitamin D-10,000 Supplement contains Vitamin D3 that supports the health of your teeth, bones, muscles, cardiovascular system, and immune function. Its optimal absorption rate makes it more potent than Vitamin D2. It is free from lactose, preservatives, gluten, eggs, tree nuts, peanuts, dairy, soy, fish, and shellfish. Thorne is a trusted brand and chosen by champions, with a proud partnership with 11 U.S. Olympic Teams and Mayo Clinic.

What We Like
Supports healthy teeth, bones, muscles, cardiovascular health, and immune function
Optimal absorption rate due to Vitamin D3, which is more potent than Vitamin D2
Free from lactose, preservatives, gluten, eggs, tree nuts, peanuts, dairy, soy, fish, and shellfish
#TOP 6

Vitamin D Supreme 5000 IU + K2 Supplement

Vitamin D Supreme 5000 IU + K2 Supplement Cover
Designs for Health Vitamin D Supreme - Vitamin D 5000 IU with 2000mcg Vitamin K as MK4 for Bone Health, Heart Health, Mood & Immune Support - Vitamin D3 Enhanced with GG Supplement (60 Capsules)

Vitamin D Supreme 5000 IU + K2 Supplement by Designs for Health is a gluten-free, easy-to-swallow capsule that supports your immune system and bone health. It comes with bioavailable vitamin D3 (5000 IU), vitamin K1 and K2, and a complementary bone and immune supportive compound, GG. The formula includes vitamin K2 mk-4, a premium form of vitamin K that works synergistically with vitamin D to support optimal bone, cardiovascular, and immune system health.

What We Like
Contains clinically relevant amounts of bioavailable vitamin D3, vitamin K1 and K2, and a complementary bone and immune supportive compound, GG
Features vitamin K2 mk-4, a premium form of vitamin K that works synergistically with vitamin D to support optimal bone, cardiovascular, and immune system health
Gluten-free and comes in an easy-to-swallow capsule
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Does vitamin D help with cardiovascular?

The findings suggest that vitamin D supplementation does not confer cardiovascular protection and is not indicated for this purpose. Observational studies have suggested an inverse association between serum 25-hydroxyvitamin D levels and risk of cardiovascular disease (CVD) events.

2. How does vitamin D affect cardiovascular disease?

Vitamin D has received widespread attention for its potential role in preventing cardiovascular disease (CVD) and type 2 diabetes mellitus. Several epidemiological studies have suggested that individuals with low blood levels of vitamin D have increased risks of heart disease, stroke, hypertension, and diabetes.

3. What is the best supplement for cardiovascular health?

What are the best heart health supplements?. Omega-3 fatty acids.Magnesium.Inositol.Folate.Grape seed extract.Coenzyme CoQ10.Vitamin D.

4. Can you take vitamin D if you are on heart medication?

Use vitamin D cautiously if you're taking drugs processed by these enzymes. Digoxin (Lanoxin). Avoid taking high doses of vitamin D with this heart medication. High doses of vitamin D can cause hypercalcemia, which increases the risk of fatal heart problems with digoxin.

Editor's Notes

During our vitamin d supplement for cardiovascular health research, we found 24 vitamin d supplement for cardiovascular health products and shortlisted 6 quality products. We collected and analyzed 512,792 customer reviews through our big data system to write the vitamin d supplements for cardiovascular health list. We found that most customers choose vitamin d supplements for cardiovascular health with an average price of $17.96.

The vitamin d supplements for cardiovascular health are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin d supplements for cardiovascular health, including THORNE, Sports Research, Pure Encapsulations, Designs for Health. The seller of top 1 product has received honest feedback from 48,360 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.