Best Omega 3 Supplements for Cholesterol Support of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 28, 2026

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Omega 3 supplements have been shown to support healthy cholesterol levels. These supplements contain essential fatty acids that can help reduce inflammation and improve heart health. Omega 3s also help to lower triglyceride levels, which can contribute to high cholesterol. Additionally, these supplements have been found to improve overall cardiovascular function and reduce the risk of heart disease. With regular use, Omega 3 supplements can be a beneficial addition to a healthy lifestyle.

At a Glance: Our Top Picks

Nordic Naturals Ultimate Omega, Lemon Flavor Cover #TOP 1
Nordic Naturals Ultimate Omega, Lemon Flavor
ftb score rating icon 9.8
NatureWise Omega 3 Fish Oil Supplement Cover #TOP 2
NatureWise Omega 3 Fish Oil Supplement
ftb score rating icon 9.7
Nature Made Fish Oil 1200 mg Softgels Cover #TOP 3
Nature Made Fish Oil 1200 mg Softgels
ftb score rating icon 9.5

Top 10 Omega 3 Supplements for Cholesterol Support

Nordic Naturals Ultimate Omega, Lemon Flavor

RUS-01804
Nordic Naturals Ultimate Omega, Lemon Flavor Cover
Nordic Naturals Ultimate Omega, Lemon Flavor - 90 Soft Gels - 1280 mg Omega-3 - High-Potency Omega-3 Fish Oil Supplement with EPA & DHA - Promotes Brain & Heart Health - Non-GMO - 45 Servings

Nordic Naturals Ultimate Omega is a high-potency fish oil supplement with 1280 mg of omega-3 fatty acids per serving. It is designed to support heart, brain, eye, and immune health, and is free of gluten, dairy, and artificial colors, flavors, and preservatives. Customers report that it is easy to swallow and has no fishy burps, and that it has helped with mental clarity, stamina, and dry eyes.

What We Like
No fishy aftertaste
High potency omega-3 dose
Easy to swallow soft gels
Supports heart and brain health
Gentle on digestion

NatureWise Omega 3 Fish Oil Supplement

nw11150
NatureWise Omega 3 Fish Oil Supplement Cover
NatureWise Extra-Strength Omega 3 Fish Oil Supplement - 1000mg per Serving - 600 EPA & 400 DHA and Vitamin E - Support for Heart & Brain Health - Lemon Flavor, GMO-Free - 60 Softgels[1-Month Supply]

NatureWise Omega 3 Lemon Softgels offer a powerful combination of omega-3 fatty acids and vitamin E to support your heart, brain, joints, and eyes. With 600mg EPA and 400mg DHA, these softgels provide extra strength for overall health. Say goodbye to fishy burps and smells as the lemon flavor neutralizes any strong odors. Gluten-free and non-GMO, these softgels are made with premium ingredients in the USA, ensuring quality. Enjoy the benefits of essential fatty acids and protective vitamin E in one convenient supplement.

What We Like
No fishy aftertaste
High EPA/DHA content
Lemon flavor coating
Includes Vitamin E
Non-GMO formula

Nature Made Fish Oil 1200 mg Softgels

Nature Made Fish Oil 1200 mg Softgels Cover
Nature Made Fish Oil Omega 3 Supplements, 1200mg Softgels, Omega 3 Fish Oil for Healthy Heart Support, 100 Softgels, 50 Day Supply

Nature Made Fish Oil 1200 mg Softgels is a heart health support supplement containing 100 purified softgels of Omega 3 Fish Oil, providing 720 mg Omega-3 fatty acids (600 mg EPA and DHA) per serving. It is gluten-free and dairy-free with no added color and artificial flavors, and recommended for adults to take two softgels daily with water and a meal. This fish oil supplement is produced by the number 1 Pharmacist Recommended Vitamin & Supplement Brand*

What We Like
High-quality fish oil
No fishy aftertaste
Easy to swallow softgels
Supports heart and joint health
Good value for money

NOW Supplements Omega-3 Softgels

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Amber
NOW Supplements Omega-3 Softgels Cover
NOW Foods Supplements, Omega-3 180 EPA / 120 DHA, Molecularly Distilled, Cardiovascular Support*, 200 Softgels

NOW Supplements Omega-3 Softgels are a great way to support heart health. Each softgel contains 1,000 mg of fish oil, with 180 EPA/120 DHA, and is made of natural fish oil concentrate manufactured under strict quality control standards. It is Non-GMO, Quality GMP Assured, and Kosher (contains gelatin). Customers have reported that the softgels are easy to swallow, have no flavor, and help with pain.

What We Like
No fishy aftertaste
Easy to swallow
High quality and purity
Gentle on stomach
Great value for price

Thorne Super EPA Omega-3 Supplement

SP608
Thorne Super EPA Omega-3 Supplement Cover
THORNE - Super EPA - Omega-3 Fatty Acids EPA 425mg & DHA 270mg Supplement - Support Brain, Cardiovascular, Joints & Skin* - Gluten, Dairy & Soy-Free - 90 Gelcaps

Thorne Super EPA is a high-quality omega-3 fatty acid supplement that provides 425mg of EPA and 270mg of DHA per serving. It supports a healthy heart, brain, cardiovascular system, joints, and skin. The distillation process removes heavy metals and other contaminants, making it a safe and reliable choice. Customers appreciate the lack of fishy taste or smell, and the customer service is excellent. However, the capsules are large and the price is higher than other brands.

What We Like
High quality supplements
Trusted brand reputation
Easy to swallow
No aftertaste or fishy smell
Supports energy and immunity

Viva Naturals Triple-Strength Wild Caught Fish Oil

LH-VLJY-9823
Viva Naturals Triple-Strength Wild Caught Fish Oil Cover
Triple Strength Omega 3 Fish Oil Supplement for Women and Men – 2500 mg High-Potency, Easy-to-Absorb Re-esterified Triglyceride Form, Pescatarian-Friendly DPA EPA DHA Omega 3 Supplement, 180 Softgels

Viva Naturals Triple-Strength Wild Caught Fish Omega-3 Fish Oil is a high-quality supplement that provides 2,200 mg of fish oil per serving, including 1,400 mg of EPA and 480 mg of DHA. It is designed for better absorption, with no fishy aftertaste, and is IFOS Certified, gluten-free and Non-GMO for quality, purity and potency. Customers have reported improved cardiovascular and brain health, as well as improved skin and eye health.*

What We Like
No fishy aftertaste
High EPA and DHA content
IFOS certified purity
Easy to swallow softgels
Reasonable price
#TOP 7

Nutricost Omega 3 Fish Oil Softgels

NTC-31053
Multicolor
Nutricost Omega 3 Fish Oil Softgels Cover
Nutricost Omega 3 Fish Oil - 2500MG, 120 Softgels (40 Serv) - Fish Oil, Wild Caught! 1200mg EPA 850mg DHA - Non-GMO, Gluten Free

Nutricost Omega 3 Fish Oil Softgels are made from wild caught fish and contain 2500mg of Omega-3 fatty acids per serving. With 1200mg EPA and 910mg DHA, these softgels are triple-strength and provide important nutritional support for your overall health. Non-GMO, gluten-free, and third-party tested, they are manufactured in an FDA registered facility that is GMP compliant.

What We Like
High EPA and DHA content
No fishy aftertaste
Easy-to-swallow capsules
Excellent value for price
Supports joint and heart health
#TOP 8

Nature Made Extra Strength Omega-3 Fish Oil Softgels

Nature Made Extra Strength Omega-3 Fish Oil Softgels Cover
Nature Made Extra Strength Burp Less Fish Oil Omega 3 Supplements 1400 mg Minis, Omega 3 Fish Oil as Ethyl Esters for Healthy Heart Brain Eyes Support, 60 Softgels, 30 Day Supply

Nature Made Extra Strength Omega-3 Fish Oil Softgels are a dietary supplement that provide healthy heart, brain and eyes support. The mini softgels are purified to remove mercury and reduce fishy burps. Each serving of two softgels provides 680mg of EPA and 250mg of DHA. The gluten-free softgels have no color added, milk, or shellfish. Simply take two softgels daily with water and a meal for optimal absorption.

What We Like
no fishy aftertaste
easy to swallow
odorless formula
good value
health benefits

Nordic Naturals Omega-3

RUS-02759
Nordic Naturals Omega-3 Cover
Nordic Naturals Omega-3, Lemon Flavor - 90 Soft Gels - 690 mg Omega-3 - Fish Oil - EPA & DHA - Immune Support, Brain & Heart Health, Optimal Wellness - Non-GMO - 45 Servings

Nordic Naturals Omega-3 is a high-quality fish oil supplement that provides essential fatty acids EPA and DHA to support heart, brain, eye, and immune health. It is perfect for those new to fish oil, as it offers a generous serving of omega-3s in soft gels. The triglyceride molecular form ensures better absorption and the lemon flavor eliminates the unpleasant fishy burps. Crafted from fresh, wild-caught, omega-rich fish, Nordic Naturals guarantees purity. They are committed to using only non-GMO, gluten- and dairy-free ingredients with no artificial colors, flavors, or preservatives. With Nordic Naturals Omega-3, you can enjoy the benefits of omega-3s for optimal wellness.

What We Like
No fishy aftertaste
High purity and third-party tested
Easy to swallow softgels
Supports brain and heart health
Wild-caught, sustainable sourcing
#TOP 10

Micro Ingredients Triple Strength Omega-3 Fish Oil Softgels

Micro Ingredients
Micro Ingredients Triple Strength Omega-3 Fish Oil Softgels Cover
Micro Ingredients Triple Strength Omega 3 Fish Oil Supplements 4,200mg Per Serving, 240 Softgels – Lemon Flavored – Burpless | EPA 1,200mg + DHA 900mg | Deep Sea Fish

Micro Ingredients Triple Strength Omega-3 Fish Oil Softgels are a premium non-GMO omega 3 fatty acid supplement that supports heart health, brain health, bone and joint support, and immune support. Each pouch contains 200 potent softgels that are infused with a sweet lemon flavor and made with burpless enteric coated technology. Every 3-softgel serving provides 1200mg EPA with 900mg DHA from wild-caught Norwegian fresh fish. The specific triglyceride omega 3 fish oil is purified to remove heavy metals like mercury and any other harmful contaminants. Made without soy, dairy, gluten, flavors, preservatives, colors, and tree nuts, this supplement is safe, pure, and potent.

What We Like
No fishy aftertaste
Burpless formula
High EPA/DHA content
Doctor recommended
Good value price
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Are omega-3 supplements good for high cholesterol?

There's strong evidence that omega-3 fatty acids can significantly reduce blood triglyceride levels. There also appears to be a slight improvement in high-density lipoprotein (HDL, or "good") cholesterol, although an increase in levels of low-density lipoprotein (LDL, or "bad") cholesterol also was observed.

2. Which Omega is best for cholesterol?

Omega-3 fatty acids have been promoted to help lower triglyceride levels The American Heart Association recommends that you eat non-fried fatty fish (salmon, anchovies, herring, mackerel, tuna, and sardines) at least twice a week.

3. Can you take omega-3 with cholesterol medicine?

In a number of small studies, the combination of statins and omega-3 fatty acids has been consistently shown to be an effective, safe, and well-tolerated treatment for combined dyslipidemia.

4. What are the best supplements for high cholesterol?

Among the supplements that may help lower cholesterol are niacin (prescription rather than over-the-counter), soluble fiber, and phytosterols. Other cholesterol-lowering remedies such as artichoke leaf extract, garlic, coenzyme Q10, policosanol, green tea, and red yeast rice are not well supported by research.

Editor's Notes

During our omega 3 supplement for cholesterol support research, we found 24 omega 3 supplement for cholesterol support products and shortlisted 10 quality products. We collected and analyzed 615,932 customer reviews through our big data system to write the omega 3 supplements for cholesterol support list. We found that most customers choose omega 3 supplements for cholesterol support with an average price of $26.39.

The omega 3 supplements for cholesterol support are available for purchase. We have researched hundreds of brands and picked the top brands of omega 3 supplements for cholesterol support, including Nordic Naturals, NatureWise, Nature Made, NOW Foods, THORNE. The seller of top 1 product has received honest feedback from 5,040 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.