Best Vitamin B Supplements for Immune Support of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 9, 2025

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Vitamin B supplements are often recommended for their immune-boosting benefits. These supplements are available in various forms, including pills, gummies, and liquid drops. Vitamin B complex supplements contain all eight B vitamins, which work together to support the immune system, energy production, and nervous system function. Vitamin B12, in particular, is known for its role in maintaining healthy immune cells. Additionally, vitamin B6 is essential for the production of antibodies, which are crucial for fighting off infections. Vitamin B supplements can be a convenient and effective way to support overall immune health.

At a Glance: Our Top Picks

Nature's Bounty Super B-Complex Tablets Cover #TOP 1
Nature's Bounty Super B-Complex Tablets
ftb score rating icon 9.8
Nature Made Super B Complex with Vitamin C, 140 Tablets Cover #TOP 2
Nature Made Super B Complex with Vitamin C, 140 Tablets
ftb score rating icon 9.7
Bronson Vitamin B Complex with C Cover #TOP 3
Bronson Vitamin B Complex with C
ftb score rating icon 9.5

Top 10 Vitamin B Supplements for Immune Support

Nature's Bounty Super B-Complex Tablets

Nature's Bounty Super B-Complex Tablets Cover
Nature's Bounty Super B Complex with Vitamin C & Folic Acid, Immune & Energy Support, 150 tablets

Nature's Bounty Super B-Complex Tablets are a once-a-day multitasker designed to support overall health and wellbeing. With 150 coated tablets per bottle, this supplement contains key B vitamins that help with heart and nervous system health, aid in the conversion of food into fuel, and play an important role in energy metabolism. Vitamin C provides immune and antioxidant support, while Folic Acid helps with energy metabolism, and promotes the health of pregnant women. These tablets are vegetarian-friendly, non-GMO, and free of sugar, gluten, and lactose.

What We Like
Improved blood work for vitamin B
Increased energy levels
Easy to swallow tablets
Affordable price

Nature Made Super B Complex with Vitamin C, 140 Tablets

Nature Made Super B Complex with Vitamin C, 140 Tablets Cover
Nature Made Super B Complex with Vitamin C and Folic Acid, Dietary Supplement for Immune Support, 140 Tablets, 140 Day Supply

Nature Made Super B Complex with Vitamin C and Folic Acid is a dietary supplement that offers 140 tablets for a 140-day supply. It is a gluten-free and vegan supplement that provides all 8 essential B vitamins, including folic acid and vitamin B12. This B-complex supplement helps support the immune system, a healthy brain and nervous system, and converts food into cellular energy. Adults can take one tablet daily with water and a meal. It is made in the USA with quality global ingredients and has no artificial colors, flavors, yeast, starch, or preservatives.

What We Like
Absorbs well
Provides essential B vitamins
Includes vitamin C for immune support
Easy to swallow
No bad aftertaste
#TOP 3

Bronson Vitamin B Complex with C

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Bronson Vitamin B Complex with C Cover
Bronson Vitamin B Complex with Vitamin C - Immune Health, Energy Support & Nervous System Support - Non-GMO, 360 Vegetarian Capsules

Bronson B-Complex Plus C is designed to support your immune system, energy levels, and nervous system health. Each vegetarian capsule combines all essential B vitamins along with Vitamin C, making it easy for you to replenish your daily nutrient needs. With a focus on quality, this formula is non-GMO, gluten-free, and soy-free, ensuring you get a premium supplement. Trusted since 1960, Bronson's commitment to health is backed by pharmacists who recognized the benefits of vitamin supplementation, making it a reliable choice for your wellness journey.

What We Like
Comprehensive B vitamin support
Boosts immune health
Energy enhancement
High-quality ingredients
#TOP 4

BioSchwartz B-Complex with Vitamin C Supplement - 60ct

BIO-BCOMPLEX-60-GS-1
BioSchwartz B-Complex with Vitamin C Supplement - 60ct Cover
Vitamin B Complex with Vitamin C for Maximum Absorption - Methylcobalamin b12 & Folate Folic Acid Supplement - Vitamins B1 B2 B3 B5 B6 B7 B9 for Immune Energy & Nervous System Support - Non-GMO -60ct

BioSchwartz B-Complex with Vitamin C is a supplement that contains all B vitamins, including B12, B7, and B9, as well as folic acid and vitamin C. This supplement supports natural energy levels and cognitive performance, and its capsules are designed for maximum absorption of nutrients. It is free of common allergens such as soy, gluten, and tree nuts, and it does not contain preservatives or artificial colorants. BioSchwartz B-Complex with Vitamin C is formulated by experienced healthcare professionals in the USA, following strict GMP guidelines.

What We Like
Contains all essential B vitamins and vitamin C for natural energy and cognitive performance support.
Designed for maximum absorption of nutrients, making them work harder for you.
Free of common allergens such as soy, gluten, and tree nuts, as well as preservatives and artificial colorants.

Nature's Nutrition B Complex Plus Vitamin C

NNBComplexPlus120
Nature's Nutrition B Complex Plus Vitamin C Cover
Vitamin B Complex Capsules with Vitamins B1 B2 B3 B6 B12 B100 C Biotin Folate & Folic Acid - Supplement for Energy, Brain, & Immune Support - Super B Vitamin Complex for Women & Men - 120 Vegan Pills

Nature's Nutrition B Complex Plus Vitamin C is a high-quality vitamin B supplement that provides optimal amounts of B1, B2, B4, B5, B6, B7, B9, and B12 vitamins. This powerful and natural supplement is designed to support energy, stress, immune system, and nervous system. The added vitamin C, folic acid, and biotin help in immune support and energy support. The capsules are made with the highest quality ingredients, vegan, and bottled in the USA. Nature's Nutrition B Complex is perfect for all adults, men, and women seeking stress and energy support.

What We Like
Natural energy support
Optimal amounts of B vitamins
Immune system support
#TOP 6

Thorne Stress B-Complex - 60 Capsules

B107-R
Thorne Stress B-Complex - 60 Capsules Cover
THORNE Stress B-Complex - Vitamins B2, B6, B12, and Folate in Highly-Absorbable and Active Forms - Extra Vitamin B5 for Adrenal Support, Stress Management and Immune Function - 60 Capsules

Thorne Stress B-Complex is a gluten-free dietary supplement that supports stress management, adrenal and immune functions, and optimal wellness. With an optimal balance of essential B vitamins, including extra vitamin B5, it helps the body's natural ability to manage stress and promote healthy adrenal and immune functions. Each B vitamin works synergistically to support multiple functions throughout the body, such as healthy energy production, red blood cell formation, and neurological function. This supplement is free from gluten, eggs, tree nuts, peanuts, dairy, soy, fish, and shellfish.

What We Like
Supports stress management and immune function
Contains an optimal balance of essential B vitamins, including extra vitamin B5, to promote healthy adrenal function
Works synergistically to support multiple functions throughout the body
Gluten-free and free from common allergens
Trusted brand chosen by champions and trusted by 100+ pro teams
#TOP 7

Nature Made Super B Complex with Vitamin C and Folic Acid

Nature Made Super B Complex with Vitamin C and Folic Acid Cover
Nature Made Super B Complex with Vitamin C and Folic Acid, Dietary Supplement for Immune Support, 360 Tablets, 360 Day Supply

Nature Made B Complex is a dietary supplement designed to support the immune system, brain, and nervous system. It contains all 8 essential B vitamins, including Folic Acid (B9) and Vitamin B12. With a 360-day supply, you can easily incorporate this supplement into your daily routine. Simply take one tablet with water and a meal. Made in the USA with quality global ingredients, this gluten-free supplement is free from artificial flavors and colors. It is also United States Pharmacopeia (USP) Verified and is the #1 Pharmacist Recommended Vitamin & Supplement Brand*. Boost your immune system and promote overall health with Nature Made B Complex.

What We Like
Immune support
Supports brain and nervous system
360-day supply

Totaria 13-in-1 Vitamin B Complex

Totaria
TORGSZS00028-1
Totaria 13-in-1 Vitamin B Complex Cover
13-in-1 Vitamin B Complex Plus with Vitamin B1, B2, B3 (Niacinamide), B4, B5, B6, B7 (Biotin), B8 (Inositol), B9 (Folate), B12, C, D3, K2 - Energy, Nerve, Immune, Skin Support - 120 Vegan Capsules

Totaria B-Complex Plus offers a comprehensive blend of 13 essential B vitamins to support your energy, nerves, immune system, and skin health. This supplement is tailored for both men and women, aiding in hormone balance, blood health, and skin maintenance. With benefits ranging from mood improvement to metabolism support, it covers various aspects of your well-being. Made from high-quality vegan ingredients, these capsules are gluten-free and non-GMO, ensuring safety and reliability. Totaria prioritizes customer satisfaction, making it a trustworthy choice for your health needs.

What We Like
Comprehensive B vitamin blend
Supports energy and skin health
Safe, premium quality ingredients
#TOP 9

Integrative Therapeutics - Active B-Complex

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Integrative Therapeutics - Active B-Complex Cover
Integrative Therapeutics Active B-Complex - Energy Metabolism Support* - B-Complex Vitamin Supplement with 8 B-Vitamins, Vitamin B12, Folate, Choline - 60 Capsules

Integrative Therapeutics - Active B-Complex supplement provides all 8 B-vitamins in a high-potency blend containing the active forms of vitamins B2, B6, B12, and folate. It supports cellular energy production, metabolism of carbohydrates, proteins, and fats, and healthy brain function. Additionally, it plays essential roles in cell function, growth, and energy production, as well as the nervous system's synthesis of serotonin, dopamine, and GABA. This gluten-free and vegan formula is free of wheat, soy, dairy, and artificial colors, flavors, or preservatives.

What We Like
High-potency blend of all 8 B-vitamins
Supports cellular energy production and metabolism
Plays essential roles in cell function and nervous system synthesis
Formulated with highly bioavailable L-methylfolate
Gluten-free and vegan, free of artificial additives
#TOP 10

Amazon Solimo Vitamin B12 Gummies

Amazon Basics
SMARA-HPC-7238
Amazon Solimo Vitamin B12 Gummies Cover
Amazon Basics Vitamin B12 3000 mcg Gummies, Normal Energy Production and Metabolism, Immune System Support, Raspberry, 100 Count (2 per serving) (Previously Solimo)

The Amazon Solimo Vitamin B12 Gummies support energy production and metabolism and promote healthy immune function, while also aiding in normal brain function and cognition. The raspberry flavored vegan gummies come with 100 gummies per bottle, enough for a one-and-a-half month supply when taken daily at listed serving size. The gummies are gluten-free, and do not contain wheat, dairy, soy, or egg.

What We Like
Supports energy production and metabolism
Promotes healthy immune function
100 gummies per bottle, enough for a one-and-a-half month supply
Gluten-free, free of wheat, dairy, soy, and egg
Refund available for any reason within a year of purchase
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Does Vitamin B complex help immune system?

Vitamin B complex helps to support a healthy immune system by supporting cell health, red blood cells, energy levels and cardiovascular health, among other functions. This means it's important to make sure you not only get enough vitamin B12, but vitamin B as a whole.

2. Which B vitamin helps the immune system?

Vitamin B6 is in charge of keeping the immune system strong, making new red blood cells, and transporting oxygen throughout the body. Vitamin B has also been shown to improve migraines. Foods rich in pyridoxine are chicken, salmon, tuna, leafy greens, and chickpeas.

3. Is taking vitamin B complex good for you?

B vitamins play a vital role in maintaining good health and well-being. As the building blocks of a healthy body, B vitamins have a direct impact on your energy levels, brain function, and cell metabolism. Vitamin B complex may help prevent infections and help support or promote: cell health.

4. Should I take B12 or B complex?

When it comes to the issue of vitamin B12 vs B complex, both types of vitamins are crucial. If you're lacking B12, consume more of it via supplements or food. If you're lacking vitamin B in general, consider B complex vitamins instead. Overall, both vitamins are essential nutrients.

Editor's Notes

During our vitamin b supplement for immune support research, we found 24 vitamin b supplement for immune support products and shortlisted 10 quality products. We collected and analyzed 476,014 customer reviews through our big data system to write the vitamin b supplements for immune support list. We found that most customers choose vitamin b supplements for immune support with an average price of $19.96.

The vitamin b supplements for immune support are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b supplements for immune support, including Nature's Bounty, Nature Made, Bronson, BioSchwartz, Nature's Nutrition. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.