Best Vitamin B6 Supplements for Immune Support of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 20, 2026

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Vitamin B6 supplements are a popular choice for individuals looking for immune support. This essential vitamin plays a crucial role in the production of antibodies and white blood cells that help fight off infections and diseases. Vitamin B6 also helps regulate the body's inflammatory response, which can reduce the risk of chronic inflammation and related health issues. These supplements come in various forms, including capsules, tablets, and gummies, making it easy for individuals to incorporate them into their daily routine. It's important to consult with a healthcare professional before starting any new supplement regimen to ensure it's safe and effective for individual needs.

At a Glance: Our Top Picks

Seeking Health Vitamin B6 Supplement (100 Capsules) Cover #TOP 1
Seeking Health Vitamin B6 Supplement (100 Capsules)
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Pure Encapsulations P5P 50 Vitamin B6 Supplement Cover #TOP 2
Pure Encapsulations P5P 50 Vitamin B6 Supplement
ftb score rating icon 9.7
Bronson Vitamin B6 Supplement - 250 Tablets Cover #TOP 3
Bronson Vitamin B6 Supplement - 250 Tablets
ftb score rating icon 9.5

Top 7 Vitamin B6 Supplements for Immune Support

#TOP 1

Seeking Health Vitamin B6 Supplement (100 Capsules)

P5P-100-CAPS
Seeking Health Vitamin B6 Supplement (100 Capsules) Cover
Seeking Health P-5-P (Pyridoxal 5-Phosphate) - Immune Health & Homocysteine Metabolism Support - Support Energy Production with Bioavailable Vitamin B6-25, 100 Capsules

Seeking Health Vitamin B6 Supplement provides 25mg of active vitamin B6, pyridoxal-5-phosphate, which supports healthy cognitive function, immune system, and metabolism. It is suitable for vegans and vegetarians who may not receive adequate B6 levels without animal food sources. The capsules are bioavailable, easy to swallow, and free from common allergens and artificial ingredients. Seeking Health ensures consistent quality by carefully sourcing, researching, and testing every ingredient.

What We Like
Provides targeted support for healthy protein metabolism, brain function, cognitive development, homocysteine metabolism support, and immune system function
Suitable for vegans and vegetarians who may not receive adequate B6 levels without animal food sources
Offers bioavailable, easy-to-swallow pyridoxal-5-phosphate capsules

Pure Encapsulations P5P 50 Vitamin B6 Supplement

Pure Encapsulations P5P 50 Vitamin B6 Supplement Cover
Pure Encapsulations P5P 50 - Active Vitamin B6 - Supports Energy Metabolism & Brain Health* - Gluten Free & Non-GMO - 60 Capsules

Pure Encapsulations P5P 50 Vitamin B6 Supplement is a high-quality supplement that provides activated vitamin B6 in the form of Pyridoxal 5' phosphate (P5P). P5P is an essential coenzyme in the metabolism of carbohydrates, proteins, and the release of glycogen for energy production. It also helps maintain the balance of sodium and potassium to regulate body fluids and promote healthy nervous and musculoskeletal system function.

What We Like
High product quality
Minimal unnecessary ingredients
Supports nerve health
Improves sleep quality
Helps with B6 deficiency

Bronson Vitamin B6 Supplement - 250 Tablets

Bronson Vitamin B6 Supplement - 250 Tablets Cover
Bronson Vitamin B6 100mg Premium Vitamin B6 Supplement, 250 Tablets

The Bronson Vitamin B6 Supplement is a premium quality supplement that promotes protein metabolism and immune function. Its superior quality is backed by laboratory tests and manufactured at a cGMP registered facility, making it a trusted choice since 1960. This supplement is suitable for adult use, comes in tablet form, and is unflavored.

What We Like
Improved energy levels
Supports brain function
Good value for price
No aftertaste
Easy to take

Natures Craft Vitamin B6 Gummies

Natures Craft Vitamin B6 Gummies Cover
Potent Vitamin B6 Gummies for Adults - Potent Vitamin B Complex Supplements for Men & Women for Nervous System Support Mood & Immune System - Vegan Pyridoxine Chews for Energy & Metabolism - 30 Ct

Natures Craft B6 Gummies are kosher and vegan vitamin B gummies for women and men. These delicious gummies provide real support for common monthly concerns such as mood balancing, bloating relief, and reducing cramps. They are also great for supporting your mind and nervous system due to their ability to promote amino acid metabolism in the brain. Made with a clean formula, these gummies are non-GMO, gluten-free, vegan, and kosher, with no artificial color dyes or flavors. Natures Craft is a trusted brand known for their high-quality adult gummy vitamins and supplements, offering real wellness in all shapes and forms.

What We Like
Kosher and vegan
Supports mood balance
Reduces cramps

Vitamatic Vitamin B6

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Vitamatic Vitamin B6 Cover
Vitamatic Vitamin B6 (Pyridoxine HCI), 500 mg – 120 Vegetarian Tablets Promotes Energy Production, Boosts Metabolism & Immune Health Support

Vitamatic B6 is a high-quality Vitamin B6 supplement that promotes energy production, boosts metabolism, and supports immune health. It also supports healthy cardiovascular and nervous system function. With its non-GMO formula and gluten-free composition, it caters to a wide range of dietary needs. The supplement is free of sugar, starch, soy, yeast, corn, wheat, egg, artificial color, flavor, and preservatives, making it a natural and healthy choice for daily supplementation. Made in the USA with strict GMP standards, Vitamatic B6 ensures the highest quality and safety for its users.

What We Like
Promotes energy production
Boosts metabolism
Supports immune health
#TOP 6

Vitamatic Vitamin B6 100mg - Berry Flavor Gummies

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Vitamatic Vitamin B6 100mg - Berry Flavor Gummies Cover
Vitamatic Vitamin B6 100mg - Berry Flavor - 60 Pectin Based Gummies - Supports Nervous System

Vitamatic Vitamin B6 100mg - Berry Flavor Gummies are a tasty and convenient way to support your nervous system, boost metabolism, energy production, and immune health. The natural berry flavor makes them a delicious treat that you'll look forward to taking every day. These gummies are Non-GMO and Gluten Free, and the Pectin Based formula is suitable for both vegans and vegetarians. Plus, they're free of soy, yeast, wheat, egg, artificial color, flavor, and preservatives.

What We Like
Delicious natural berry flavor
Promotes energy production, boosts metabolism and immune health support
Non-GMO formula - Gluten Free
Pectin Based - Vegan Friendly & Suitable for Vegetarian
Free of soy, yeast, wheat, egg, artificial color, flavor, & preservatives
#TOP 7

Life Extension Pyridoxal 5'-Phosphate 100 mg P5P

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Life Extension Pyridoxal 5'-Phosphate 100 mg P5P Cover
Life Extension Pyridoxal 5'-Phosphate Caps—Vitamin B6, 100 mg, Bioactive B6 for Cardiovascular, Kidney & Nerve Health—Gluten-Free, Non-GMO, Vegetarian—60 Vegetarian Capsules

Life Extension Pyridoxal 5'-Phosphate 100 mg P5P is a gluten-free, non-GMO supplement that provides metabolically active vitamin B6, which inhibits glycation reactions, supports eye, heart and brain health, healthy kidney function, and a healthy immune response. Formulated with the finest raw ingredients with the purity and potency your body deserves.

What We Like
Gluten-free and non-GMO
Supports eye, heart, and brain health
Inhibits glycation reactions, which helps keep you young on the inside
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is vitamin B6 good for your immune system?

Vitamin B6 helps maintain a normal amount of this amino acid in your blood. A stronger immune system. Vitamin B6 helps chemical reactions in the immune system, helping it work better. Eating foods rich in vitamin B6 will help your body guard against infection.

2. Is B6 good for Covid?

These suggest that vitamin B6 may ameliorate the severity of COVID-19 by exerting its anti-oxidative and anti-inflammatory actions in lung, a primary target organ for COVID-19 virus infection.

3. What is the supplement B6 good for?

Vitamin B6 is needed for the proper function of sugars, fats, and proteins in the body. It's also necessary for the development of the brain, nerves, skin, and many other parts of the body. It's found in cereals, legumes, and eggs, and often used with other B vitamins in vitamin B complex products.

4. Is vitamin B6 an anti inflammatory?

For several years vitamin B6 and its vitamers (B6) were recognized as antioxidant and antiinflammatory and in modulating immunity and gene expression.

Editor's Notes

During our vitamin b6 supplement for immune support research, we found 24 vitamin b6 supplement for immune support products and shortlisted 7 quality products. We collected and analyzed 46,404 customer reviews through our big data system to write the vitamin b6 supplements for immune support list. We found that most customers choose vitamin b6 supplements for immune support with an average price of $12.19.

The vitamin b6 supplements for immune support are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b6 supplements for immune support, including Seeking Health, Pure Encapsulations, Bronson, Natures Craft, Vitamatic. The seller of top 1 product has received honest feedback from 23,519 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.