Best Vitamin B-Complex Supplements for Heart Health of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 20, 2026

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Vitamin B-Complex supplements have been found to be beneficial for maintaining heart health. These supplements contain a combination of vitamins, including B1, B2, B3, B5, B6, B7, B9, and B12, which work together to support the cardiovascular system. Vitamin B1 helps to maintain a healthy heart rhythm, while B6 and B12 help to reduce homocysteine levels, which can contribute to heart disease. Additionally, B3 has been shown to help lower cholesterol levels. Taking a daily Vitamin B-Complex supplement may be a beneficial addition to a heart-healthy lifestyle.

At a Glance: Our Top Picks

NUTRAHARMONY Vitamin B Complex Cover #TOP 1
NUTRAHARMONY Vitamin B Complex
ftb score rating icon 9.8
Life Extension BioActive Complete B Complex Cover #TOP 2
Life Extension BioActive Complete B Complex
ftb score rating icon 9.7
Integrative Therapeutics - Active B-Complex Cover #TOP 3
Integrative Therapeutics - Active B-Complex
ftb score rating icon 9.5

Top 8 Vitamin B-Complex Supplements for Heart Health

NUTRAHARMONY Vitamin B Complex

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NUTRAHARMONY Vitamin B Complex Cover
Vitamin B Complex for Men & Women - Riboflavin B2, B12, B1, B3, B5, B6, B7, B8, B9 | Vitamin C, Choline, Inositol - B-Complex Supplement - Energy, Brain & Heart Support - Made in USA, 60 Vegan Caps

NUTRAHARMONY B Complex is a high-quality vitamin supplement that provides a full-spectrum of B-complex vitamins along with vitamin C, Choline, and Inositol. With a daily dose of 754 mg per serving, this B-complex supports energy, brain, and mood, while strengthening and maintaining the immune system. It also supports the work of the cardiovascular and nervous systems, making it a comprehensive health support. Made in the USA with care and love, these capsules are free from GMOs and artificial additives. If you're looking for a potent B-complex vitamin supplement that delivers results, NUTRAHARMONY B Complex is the one for you!

What We Like
Increases energy levels
Supports cognitive function
Promotes hair growth
Gentle on stomach
Good value

Life Extension BioActive Complete B Complex

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Life Extension BioActive Complete B Complex Cover
Life Extension BioActive Complete B-Complex, Heart, Brain and Nerve Support, Healthy Energy, Metabolism, Complete B Complex, 60 Vegetarian Capsules

Energize and optimize your body’s metabolic processes with BioActive Complete B Complex. This supplement offers a complete spectrum of biologically active vitamin Bs that your body needs to support optimal organ function, healthy metabolism, cognitive health, and energy production. Made with the finest raw ingredients, this gluten-free, non-GMO supplement provides the perfect complement to any nutritional regimen.

What We Like
Boosts energy levels
Methylated B12 and folate
High absorption bio-active formula
Good value for money
Easy to swallow capsules

Integrative Therapeutics - Active B-Complex

Integrative Therapeutics - Active B-Complex Cover
Integrative Therapeutics Active B-Complex - Cellular Energy, Immune Function & Heart Health Support with Vitamins B2, B6 & B12* - Made for Busy Lifestyles - Gluten-Free - 60 Capsules (30 Servings)

Integrative Therapeutics - Active B-Complex supplement provides all 8 B-vitamins in a high-potency blend containing the active forms of vitamins B2, B6, B12, and folate. It supports cellular energy production, metabolism of carbohydrates, proteins, and fats, and healthy brain function. Additionally, it plays essential roles in cell function, growth, and energy production, as well as the nervous system's synthesis of serotonin, dopamine, and GABA. This gluten-free and vegan formula is free of wheat, soy, dairy, and artificial colors, flavors, or preservatives.

What We Like
Consistent energy boost
Improved mental clarity
Bioavailable B vitamin forms
No stomach upset
Supports heart health

Nature's Bounty Super B-Complex Tablets

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Nature's Bounty Super B-Complex Tablets Cover
Nature's Bounty Super B Complex Vitamins with Vitamin C & Folic Acid, Vitamins for Immune & Cellular Energy Support, 150 Tablets

Nature's Bounty Super B-Complex Tablets are a once-a-day multitasker designed to support overall health and wellbeing. With 150 coated tablets per bottle, this supplement contains key B vitamins that help with heart and nervous system health, aid in the conversion of food into fuel, and play an important role in energy metabolism. Vitamin C provides immune and antioxidant support, while Folic Acid helps with energy metabolism, and promotes the health of pregnant women. These tablets are vegetarian-friendly, non-GMO, and free of sugar, gluten, and lactose.

What We Like
Energy and focus boost
Easy to swallow tablets
Gentle on stomach
Great value, 150-count bottle
Vegetarian and allergen-free

Super B-Complex - High Strength Methylated Tablets

Super B-Complex - High Strength Methylated Tablets Cover
Igennus Super B-Complex Methylated B Vitamins, All Day Nutrient Delivery, Clean Label, MTHFR Supplement with Methylfolate & B12 Methylcobalamin, Vegan, Lab Verified, 60 Small Tablets

The Super B-Complex Tablets are a high strength, vegan and vegetarian-friendly dietary supplement that supports energy metabolism, immune and hormonal systems, homocysteine regulation, nutrient metabolism, heart function, and psychological function. These small tablets (9mm) deliver a sustained release of vitamins including Thiamine, Riboflavin-5-phosphate, Niacinamide, Calcium D-pantothenate, D-Biotin, and Pyridoxal-5-Phosphate. Additionally, the methylated vitamin forms of bioavailable folate as methylfolate and methylcobalamin (Vit B12) are used for immediate absorption. The twice daily dosing optimises B12 levels, providing all-day nutrient coverage. The tablets are GMP manufactured in the USA and MTHFR friendly (no synthetic folic acid).

What We Like
Methylated B vitamins
Noticeable energy boost
Gentle on stomach
Vegan and clean ingredients
Easy to swallow tablets
#TOP 6

Garden of Life Raw B Complex - Vitamin Code

Garden of Life Raw B Complex - Vitamin Code Cover
Garden of Life Vitamin B Complex, 120 Vegan Capsules, High Potency Vitamins for Energy & Metabolism with B6, Folate & B12 as Methylcobalamin Plus Probiotics

Garden of Life Raw B Complex - Vitamin Code is a high potency supplement that supports energy, metabolism, immune system, heart, and blood health. This B Complex supplement contains 8 whole food complexed B vitamins, raw probiotics, and enzymes that support healthy digestion. The supplement is vegan, gluten-free, kosher, and free from synthetic binders, fillers, and artificial additives.

What We Like
Whole food ingredients
Steady energy boost
No stomach discomfort
Easy to swallow
Improves mood and clarity
#TOP 7

Triquetra Health BioActive Vitamin B Complex

Triquetra Health BioActive Vitamin B Complex Cover
BioActive Vitamin B Complex - Blood Stream Ready, Methylated B Complex - Featuring Methylfolate, 3 BioActive Forms of B12, BenfoPure® B1 & Pantesin® B5 - 12 B Vitamins in Clinical Doses - 60 Servings

The Triquetra BioActive B Complex offers you B vitamins in their most effective forms, so your body can absorb them quickly without extra processing. This means you get faster support for energy, metabolism, and overall vitality. It includes three types of B12, giving you both immediate and lasting benefits to help with energy production and detox. The supplement also provides L-Methylfolate, a powerful form of B9, which can boost your brain function, mood, and help maintain healthy homocysteine levels, especially if your body struggles with methylation. Plus, it contains premium forms of B1 and B5, which work much better than standard versions to support your heart, nerves, and metabolism.

What We Like
Highly absorbable active forms
Triple B12 complex
Bioactive folate support
Enhanced B1 and B5 forms

NATURELO B Complex with Fruits and Veggies - 120 Capsules

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NATURELO B Complex with Fruits and Veggies - 120 Capsules Cover
NATURELO Vitamin B Complex,120 Capsules, Vegan, CoQ10, Methyl Folate, Biotin, Fruit & Veg Blend, Supports Energy and Healthy Stress Response, Super B Complex Vitamins for Women and Men

The NATURELO B Complex with Fruits and Veggies is a high-potency multivitamin that includes all eight B vitamins, plus important co-nutrients like Choline, Inositol, and PABA, with added organic fruits and vegetables for an extra boost of whole food nutrition. This vegan-friendly supplement contains the active, MTHFR-friendly forms of Folate, B6, and B12 that can be used directly by the body. The B complex vitamins support energy production and metabolism, heart health, and a healthy pregnancy, while promoting healthy brain and nervous system function.

What We Like
Includes all eight B vitamins plus important co-nutrients like Choline, Inositol, and PABA, with added organic fruits and vegetables for an extra boost of whole food nutrition.
Vegan-friendly supplement contains the active, MTHFR-friendly forms of Folate, B6, and B12 that can be used directly by the body.
B complex vitamins support energy production and metabolism, heart health, and a healthy pregnancy, while promoting healthy brain and nervous system function.
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Is vitamin B-complex good for heart patients?

Taking folic acid or B-complex vitamins may reduce risk for heart attack, stroke, or death due to heart disease, but most supplements do not appear to provide any benefit.

2. Is B-complex good for arteries?

Conclusions: High-dose B vitamin supplementation significantly reduces progression of early-stage subclinical atherosclerosis (carotid artery intima media thickness) in well-nourished healthy B vitamin "replete" individuals at low risk for cardiovascular disease with a fasting tHcy >or=9.1 micromol/L.

3. Is it OK to take B-complex everyday?

Since B vitamins are water-soluble, it's unlikely that you will consume too much of these nutrients through food or by taking a B-complex supplement as directed. However, taking supplements that contain excessively high and unnecessary quantities of B vitamins could lead to serious side effects.

4. Can B-complex cause heart palpitations?

There are a variety of symptoms that come with a B12 deficiency. One sign associated with the condition is experiencing heart palpitations.

Editor's Notes

During our vitamin b-complex supplement for heart health research, we found 24 vitamin b-complex supplement for heart health products and shortlisted 8 quality products. We collected and analyzed 665,880 customer reviews through our big data system to write the vitamin b-complex supplements for heart health list. We found that most customers choose vitamin b-complex supplements for heart health with an average price of $21.71.

The vitamin b-complex supplements for heart health are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b-complex supplements for heart health, including NUTRAHARMONY, Life Extension, Integrative Therapeutics, Nature's Bounty, Igennus Healthcare Nutrition. The seller of top 1 product has received honest feedback from 8,782 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.