Best Selenium Sulfide Shampoo of 2026

Lisa Bechard Avatar
Lisa Bechard
Last Updated: Jan 12, 2026

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Selenium sulfide shampoo is a medicated shampoo that is commonly used to treat dandruff and seborrheic dermatitis. It works by slowing down the production of skin cells, which can help reduce itching and flaking of the scalp. This type of shampoo is typically used only a few times a week, as overuse can cause dryness and irritation of the scalp. Selenium sulfide shampoo is available over the counter and comes in a variety of brands, strengths, and formulations to suit different needs. It is important to read and follow the instructions carefully to ensure safe and effective use.

At a Glance: Our Top Picks

Selsun Blue Medicated Anti-dandruff Shampoo Cover #TOP 1
Selsun Blue Medicated Anti-dandruff Shampoo
ftb score rating icon 9.9
Selsun Blue Moisturizing Anti-dandruff Shampoo Cover #TOP 2
Selsun Blue Moisturizing Anti-dandruff Shampoo
ftb score rating icon 9.8
Head & Shoulders Clinical Strength Dandruff Defense Shampoo Cover #TOP 3
Head & Shoulders Clinical Strength Dandruff Defense Shampoo
ftb score rating icon 9.6

Top 10 Selenium Sulfide Shampoo

#TOP 1

Selsun Blue Medicated Anti-dandruff Shampoo

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Blue
Selsun Blue Medicated Anti-dandruff Shampoo Cover
Selsun Blue Medicated Antidandruff Shampoo, Maximum Strength Scalp Treatment With Selenium Sulfide, 11 fl. oz.

Selsun Blue Medicated Anti-dandruff Shampoo for Men is a maximum-strength formula to help control tough dandruff symptoms. This medicated shampoo lathers quickly and is formulated with menthol to deliver a cooling, refreshing and soothing sensation on the scalp. It helps prevent and eliminate itchy scalp and visible flakes associated with dandruff.

What We Like
Maximum-strength anti-dandruff shampoo with 1% selenium sulfide
Lathers quickly
Formulated with menthol for a cooling and soothing sensation on the scalp
#TOP 2

Selsun Blue Moisturizing Anti-dandruff Shampoo

60352
Selsun Blue Moisturizing Anti-dandruff Shampoo Cover
Selsun Blue Moisturizing Antidandruff Shampoo, Maximum Strength Scalp Treatment With Selenium Sulfide, 11 fl. oz.

Selsun Blue Moisturizing Anti-dandruff Shampoo is a maximum-strength anti-dandruff shampoo with 1% selenium sulfide. This medicated dandruff shampoo lathers quickly and is made with aloe to help nourish and moisturize dry hair. It also helps prevent and eliminate itchy scalp and visible flakes, providing relief from dandruff symptoms.

What We Like
Maximum-strength anti-dandruff shampoo
Made with aloe to nourish and moisturize dry hair
Quick lather for easy use

Head & Shoulders Clinical Strength Dandruff Defense Shampoo

Head & Shoulders Clinical Strength Dandruff Defense Shampoo Cover
Head & Shoulders Anti-Dandruff Shampoo, Clinical Strength Intensive Itch Relief Twin Pack, 1% Selenium Sulfide, Seborrheic Dermatitis Relief, Itch Relief, 13.5 fl oz Each

Get relief from severe dandruff and seborrheic dermatitis with Head & Shoulders Clinical Strength Dandruff Defense Shampoo. This shampoo provides intensive itch relief, fights Malassezia after just one wash, and offers up to 100% dandruff protection with regular use. Made with 1% Selenium Sulfide, it provides prescription strength flake protection and is clinically proven to protect against flakes and itch associated with dandruff. With its cooling menthol infusion, this shampoo will soothe your scalp and hair for a healthy, vibrant look you'll love.

What We Like
Provides intensive itch relief
Clinically proven to protect against flakes and dandruff
Made with 1% Selenium Sulfide for prescription strength flake protection
Offers up to 100% dandruff protection with regular use
Infused with cooling menthol for a soothing effect
#TOP 4

Head & Shoulders Clinical Dandruff Shampoo and Conditioner

Head & Shoulders Clinical Dandruff Shampoo and Conditioner Cover
Head & Shoulders Anti-Dandruff Shampoo, Clinical Strength Dry Scalp Rescue Shampoo Twin Pack, 1% Selenium Sulfide, Seborrheic Dermatitis Relief, Dry Scalp 13.5 fl oz Each

Head & Shoulders Dandruff Rescue is designed to tackle both dandruff and dry scalp effectively. It features a powerful formula with 1% Selenium Sulfide, which provides strong relief from dandruff and helps prevent flaking. With regular use, you can expect up to 100% protection against visible flakes. This shampoo and conditioner duo also offers multi-symptom relief, addressing dryness and flaking associated with dandruff. Infused with manuka honey, it not only nourishes your scalp but also enhances the overall health of your hair.

What We Like
Effective dandruff relief
Prevents flaking
Moisturizes dry scalp
Infused with manuka honey
#TOP 5

Dercos Anti Dandruff Shampoo by Vichy

Dercos Anti Dandruff Shampoo by Vichy Cover
Dercos Anti Dandruff Shampoo, Dry Scalp Treatment and Itch Relief. Prescription Strength Comparable to 2% Ketoconazole, for Mild to Severe Dandruff-Prone Hair & Flaky, Itchy Scalps, 6.76 Fl. Oz.

Vichy Dercos Anti Dandruff shampoo is designed to effectively treat dandruff and relieve dry, itchy scalps. It uses 0.6% micronized selenium sulfide, a powerful ingredient that works as well as 2% ketoconazole shampoos, helping to reduce flakes and scalp irritation. This shampoo quickly controls dandruff and soothes itching, reducing redness and discomfort for a healthier scalp. Additionally, it hydrates your hair with niacinamide and glycerin, making your hair stronger, softer, and shinier while preventing breakage. It's also safe for all hair types, including color-treated and sensitive scalps, ensuring gentle yet effective care.

What We Like
Effective dandruff control
Fast itch relief
Hydrating formula
Strengthens and softens hair
Safe for sensitive scalps

Head & Shoulders Clinical Strength Dandruff Shampoo Twin Pack

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Head & Shoulders Clinical Strength Dandruff Shampoo Twin Pack Cover
Head & Shoulders Anti-Dandruff Shampoo, Clinical Strength Advanced Oil Control Twin Pack, 1% Selenium Sulfide, Seborrheic Dermatitis Relief, Oily Scalp, 13.5 fl oz Each

Head & Shoulders Clinical Strength Dandruff Shampoo Twin Pack is a powerful anti-dandruff shampoo made with 1% Selenium Sulfide for prescription strength dandruff relief and flaking protection. It provides relief from severe dandruff and seborrheic dermatitis, and is suitable for adults with oily hair. Customers have reported that it provides up to 100% dandruff protection and visible flakes with regular use, and that it relieves scalp itching and sores quickly. It also works well on Asian hair, but may leave a chemical smell after use.

What We Like
Provides up to 100% dandruff protection and visible flakes with regular use
Relieves scalp itching and sores quickly
Works well on Asian hair
#TOP 7

Selsun Blue Medicated Anti-dandruff Shampoo 1% Selenium Sulfide (2-Pack)

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Selsun Blue Medicated Anti-dandruff Shampoo 1% Selenium Sulfide (2-Pack) Cover
Selsun Blue Medicated Anti-dandruff Shampoo with Menthol, 11 fl. oz., Maximum Strength, Selenium Sulfide 1% (Pack of 2)

The Selsun Blue Anti-dandruff shampoo comes in two convenient 11-ounce bottles, giving you plenty of product to manage your scalp health. Its updated formula is designed to leave your hair feeling soft and silky, making it gentle enough for regular use. This maximum strength shampoo contains 1% selenium sulfide, a powerful ingredient that helps reduce dandruff symptoms such as itching, flaking, redness, and irritation. The quick-lathering formula thoroughly cleans your hair while the cooling menthol provides a refreshing sensation, soothing your scalp and helping to keep it comfortable throughout the day.

What We Like
Two 11-oz bottles
Softens and smooths hair
Maximum strength formula
Reduces itching and flaking
Cooling menthol relief

Amazon Basics Dandruff Shampoo 11oz

Amazon Basics
Amazon Basics Dandruff Shampoo 11oz Cover
Amazon Basics Moisturizing Dandruff Shampoo, 11 Fl Oz, Pack of 1

The Amazon Basics Dandruff Shampoo is designed to provide maximum strength relief from dandruff with its 1% Selenium Sulfide formulation. This effective ingredient targets dandruff symptoms, helping you achieve a healthier scalp. Enriched with Aloe, the shampoo also offers moisturizing benefits, ensuring that your hair remains hydrated and soft. For best results, using this shampoo twice a week can significantly alleviate dandruff issues. If you’re familiar with Selsun Blue, you might find this product a great alternative for your scalp care routine.

What We Like
Effective against dandruff
Affordable price
Good lathering capability
Leaves hair soft and shiny
#TOP 9

Selsun Blue Moisturizing Anti-dandruff Shampoo

90-8K9P-B6PR
Selsun Blue Moisturizing Anti-dandruff Shampoo Cover
Selsun Blue Moisturizing Anti-dandruff Shampoo with Aloe, 11 fl. oz., Selenium Sulfide 1% (Pack of 2)

Selsun Blue Anti-Dandruff is a powerful shampoo designed to help you fight dandruff effectively. It contains a strong 1% selenium sulfide formula that targets and reduces flakes and itching. The shampoo is enriched with aloe, which helps keep your hair hydrated and prevents dryness. You’ll also appreciate how quickly it lathers, making it easy to apply and rinse. Using this shampoo regularly can help soothe your scalp and keep it healthy, giving you a clean, flake-free look with less irritation.

What We Like
Maximum-strength formula
Aloe moisturizing
Fast lathering
Relieves itch and flakes
#TOP 10

Easyes Anti Dandruff Shampoo with Selenium Sulfide

Easyes
7 Fl Oz (Pack of 1)
Easyes Anti Dandruff Shampoo with Selenium Sulfide Cover
Easyes Anti Dandruff Shampoo with 1% Selenium Sulfide – Helps reduce Itchy Flaky Scalp, strengthens and nourishes hair, soothes the scalp, Controls Oil, 7oz

The Easyes Anti Dandruff Shampoo is designed to help you tackle flaky, itchy scalp with a powerful blend of ingredients. It combines selenium sulfide, sodium salicylate, and piroctone ethanolamine to effectively reduce dandruff and control flakes, giving your scalp relief. The shampoo also nourishes and strengthens your hair using natural extracts like thuja leaves and ginger, promoting healthier-looking strands. Additionally, it balances your scalp’s oil levels with ceramides, helping to maintain a clean, fresh feeling throughout the day. This shampoo works well for all hair types, especially if you struggle with oily or dandruff-prone scalp, making it a convenient choice for daily care.

What We Like
Triple anti-dandruff formula
Hair strengthening botanicals
Scalp oil balance
Suitable for all hair types
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What does selenium sulfide shampoo do?

Selenium sulfide shampoo is an anti-infective agent that relieves itching and flaking of the scalp. It helps remove dry, scaly particles associated with dandruff or seborrhea. It can also be used to treat fungal skin infections like tinea versicolor.

2. Why is selenium sulfide banned?

Selenium sulfide is considered a probable and reasonably anticipated carcinogen. It has been associated with potential health risks, including being fatal if swallowed or inhaled, toxicity to aquatic life, and organ damage from prolonged or repeated exposure. Due to these hazards, it is banned in some regions.

3. Can you buy selenium sulfide over the counter?

Yes, you can purchase medicated shampoos containing selenium sulfide over the counter. However, stronger formulations may require a prescription from a doctor.

4. Does selenium sulfide get rid of fungus?

Yes, selenium sulfide is effective in treating fungal infections like seborrhea and tinea versicolor. It can be applied to the skin, left to dry for 10 minutes, and then washed off. Treatment typically lasts for about 2 weeks.

5. Is selenium sulfide bad for your hair?

Selenium sulfide shampoo may cause some side effects such as skin irritation, dry skin, oily or dry hair/scalp, or temporary hair loss. If these effects persist or worsen, it is recommended to discontinue use and consult a doctor or pharmacist. Hair discoloration may also occur, but it can be minimized by thoroughly rinsing the hair after each treatment.

6. Is selenium sulfide cancerous?

Selenium sulfide is considered a potential carcinogen, as it has been shown to cause liver and lung cancer in animals. Many scientists believe that there is no safe level of exposure to carcinogens. It is important to be aware of the potential risks associated with selenium sulfide and to use it as directed by a healthcare professional.

Editor's Notes

During our selenium sulfide shampoo research, we found 48 selenium sulfide shampoo products and shortlisted 10 quality products. We collected and analyzed 352,459 customer reviews through our big data system to write the selenium sulfide shampoo list. We found that most customers choose selenium sulfide shampoo with an average price of $19.91.

The selenium sulfide shampoo are available for purchase. We have researched hundreds of brands and picked the top brands of selenium sulfide shampoo, including Selsun Blue, Head & Shoulders, Dercos, Easyes. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Lisa Bechard Avatar

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.