Best Selenium Sulfide Shampoo of 2025

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Selenium sulfide shampoo is a medicated shampoo that is commonly used to treat dandruff and seborrheic dermatitis. It works by slowing down the production of skin cells, which can help reduce itching and flaking of the scalp. This type of shampoo is typically used only a few times a week, as overuse can cause dryness and irritation of the scalp. Selenium sulfide shampoo is available over the counter and comes in a variety of brands, strengths, and formulations to suit different needs. It is important to read and follow the instructions carefully to ensure safe and effective use.
At a Glance: Our Top Picks
Top 10 Selenium Sulfide Shampoo
Selsun Blue Medicated Anti-dandruff Shampoo
Selsun Blue Medicated Anti-dandruff Shampoo for Men is a maximum-strength formula to help control tough dandruff symptoms. This medicated shampoo lathers quickly and is formulated with menthol to deliver a cooling, refreshing and soothing sensation on the scalp. It helps prevent and eliminate itchy scalp and visible flakes associated with dandruff.
Dercos Anti Dandruff Shampoo
Dercos Dandruff Shampoo is designed to tackle dandruff and soothe an itchy scalp effectively. With its 0.6% micronized selenium sulfide, it directly addresses various levels of dandruff, from mild to severe. This medicated formula also includes glycerin and niacinamide, which help reduce inflammation and keep your scalp hydrated. You'll notice relief from itching after just one use. Plus, it enhances your hair's health by minimizing breakage, retaining moisture, and increasing shine, ensuring that your hair looks great while treating dandruff.
Selsun Blue Moisturizing Anti-dandruff Shampoo
Selsun Blue Moisturizing Anti-dandruff Shampoo is a maximum-strength anti-dandruff shampoo with 1% selenium sulfide. This medicated dandruff shampoo lathers quickly and is made with aloe to help nourish and moisturize dry hair. It also helps prevent and eliminate itchy scalp and visible flakes, providing relief from dandruff symptoms.
Head & Shoulders Clinical Strength Dandruff Defense Shampoo
Get relief from severe dandruff and seborrheic dermatitis with Head & Shoulders Clinical Strength Dandruff Defense Shampoo. This shampoo provides intensive itch relief, fights Malassezia after just one wash, and offers up to 100% dandruff protection with regular use. Made with 1% Selenium Sulfide, it provides prescription strength flake protection and is clinically proven to protect against flakes and itch associated with dandruff. With its cooling menthol infusion, this shampoo will soothe your scalp and hair for a healthy, vibrant look you'll love.
Head & Shoulders Anti-Dandruff Shampoo and Conditioner Set
Head & Shoulders Clinical Strength Dandruff Defense plus Dry Scalp Rescue Shampoo and Conditioner set provides prescription strength* dandruff relief and flaking protection. It is clinically proven to protect against flakes and dryness. Infused with manuka honey, it nourishes your scalp and hair for a healthy, vibrant look you'll love.
Amazon Basics Dandruff Shampoo 11oz
The Amazon Basics Dandruff Shampoo is designed to provide maximum strength relief from dandruff with its 1% Selenium Sulfide formulation. This effective ingredient targets dandruff symptoms, helping you achieve a healthier scalp. Enriched with Aloe, the shampoo also offers moisturizing benefits, ensuring that your hair remains hydrated and soft. For best results, using this shampoo twice a week can significantly alleviate dandruff issues. If you’re familiar with Selsun Blue, you might find this product a great alternative for your scalp care routine.
Rugby Selenium Sulfide Anti-Dandruff Shampoo
This anti-dandruff shampoo contains 1% Selenium Sulfide, which is comparable to Selsun Blue, making it a highly effective formula for treating dandruff. The shampoo is designed to treat the scalp and reduce flakiness, itching, and irritation. It is suitable for both men and women and is perfect for daily use.
True+Real Moisturizing Dandruff Shampoo
Get relief from flaking and itchy scalp with True+Real Moisturizing Dandruff Shampoo. The moisturizing formula contains Aloe to nourish hair and scalp, and Selenium Sulfide 1% to prevent recurrence of symptoms. This fast-acting shampoo provides long-lasting relief for teens, adults, men, and women. Use at least twice a week or as directed by a doctor for best results. Comparable to the same ingredients as the leading brand moisturizing anti-dandruff shampoo.
Equate Dandruff Shampoo with Selenium Sulfide
YOLOMOLO Dandruff Shampoo offers an effective solution for those struggling with dandruff. With 1% selenium sulfide, this potent antifungal agent helps you tackle stubborn flakes head-on. Say goodbye to the discomfort of an itchy scalp, as this shampoo soothes irritation and promotes a more comfortable feeling. You’ll also appreciate its ability to control flaking, leaving your scalp looking clean and refreshed. Additionally, it provides gentle cleansing, ensuring your hair is not only treated for dandruff but also effectively cleaned. This shampoo makes it easy for you to maintain a healthy scalp and beautiful hair.
Dermaharmony Shampoo Bar for Dandruff, Seborrheic Dermatitis and Psoriasis
Dermaharmony 5% Sulfur 2% Salicylic Acid Shampoo Bar is a non-soap, syndet formulation with pH of 3.8 suitable for treating dandruff, seborrheic dermatitis, and psoriasis. The bar produces a bigger lather and can be used in all pH levels of soft- and hard-water. It is free of artificial fragrances, colors, sulphate, SLS, MPG, PEG, paraben and preservative. This shampoo bar is made in the USA from US and internationally sourced ingredients and outlasts multiple bottles of liquid shampoo.
Frequently Asked Questions (FAQs)
1. What does selenium sulfide shampoo do?
Selenium sulfide shampoo is an anti-infective agent that relieves itching and flaking of the scalp. It helps remove dry, scaly particles associated with dandruff or seborrhea. It can also be used to treat fungal skin infections like tinea versicolor.
2. Why is selenium sulfide banned?
Selenium sulfide is considered a probable and reasonably anticipated carcinogen. It has been associated with potential health risks, including being fatal if swallowed or inhaled, toxicity to aquatic life, and organ damage from prolonged or repeated exposure. Due to these hazards, it is banned in some regions.
3. Can you buy selenium sulfide over the counter?
Yes, you can purchase medicated shampoos containing selenium sulfide over the counter. However, stronger formulations may require a prescription from a doctor.
4. Does selenium sulfide get rid of fungus?
Yes, selenium sulfide is effective in treating fungal infections like seborrhea and tinea versicolor. It can be applied to the skin, left to dry for 10 minutes, and then washed off. Treatment typically lasts for about 2 weeks.
5. Is selenium sulfide bad for your hair?
Selenium sulfide shampoo may cause some side effects such as skin irritation, dry skin, oily or dry hair/scalp, or temporary hair loss. If these effects persist or worsen, it is recommended to discontinue use and consult a doctor or pharmacist. Hair discoloration may also occur, but it can be minimized by thoroughly rinsing the hair after each treatment.
6. Is selenium sulfide cancerous?
Selenium sulfide is considered a potential carcinogen, as it has been shown to cause liver and lung cancer in animals. Many scientists believe that there is no safe level of exposure to carcinogens. It is important to be aware of the potential risks associated with selenium sulfide and to use it as directed by a healthcare professional.
During our selenium sulfide shampoo research, we found 48 selenium sulfide shampoo products and shortlisted 10 quality products. We collected and analyzed 207,642 customer reviews through our big data system to write the selenium sulfide shampoo list. We found that most customers choose selenium sulfide shampoo with an average price of $19.82.
The selenium sulfide shampoo are available for purchase. We have researched hundreds of brands and picked the top brands of selenium sulfide shampoo, including Selsun Blue, Dercos, Head & Shoulders, RUGBY LABORATORIES, True+Real. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.