Best Ketoconazole Shampoo of 2026

Lisa Bechard Avatar
Lisa Bechard
Last Updated: Jan 12, 2026

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Ketoconazole shampoo is a medicated shampoo that is used to treat a variety of fungal infections of the skin and scalp. It contains the active ingredient ketoconazole, which works by killing the fungi that cause these infections. This shampoo is commonly used to treat conditions such as dandruff, seborrheic dermatitis, and tinea versicolor. It is available over-the-counter and can be used by both adults and children. Ketoconazole shampoo is typically used twice a week for up to four weeks, or as directed by a healthcare professional. It is important to follow the instructions carefully and to avoid getting the shampoo in the eyes or mouth.

At a Glance: Our Top Picks

Nizoral Anti-Dandruff Shampoo Cover #TOP 1
Nizoral Anti-Dandruff Shampoo
ftb score rating icon 9.8
Nizoral Anti-Dandruff Shampoo 1% Cover #TOP 2
Nizoral Anti-Dandruff Shampoo 1%
ftb score rating icon 9.7
Nizoral Anti-Dandruff Shampoo 1% Ketoconazole Cover #TOP 3
Nizoral Anti-Dandruff Shampoo 1% Ketoconazole
ftb score rating icon 9.5

Top 10 Ketoconazole Shampoo

Nizoral Anti-Dandruff Shampoo

20053076192401
7 Fl Oz
Nizoral Anti-Dandruff Shampoo Cover
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, Fresh Scent, 7 Fl Oz

Fight dandruff and flakiness with Nizoral Anti-Dandruff Shampoo. Made with ketoconazole 1%, this clinically proven shampoo helps relieve itchy and flaky scalps, leaving hair manageable and shiny. It works on all hair types and is effective in controlling dandruff and itchiness. Use it twice a week between regular shampoos for best results.

What We Like
Effective dandruff treatment
Pleasant fresh scent
Easy to use
Softens hair
Good value for size

Nizoral Anti-Dandruff Shampoo 1%

20053076192654
Nizoral Anti-Dandruff Shampoo 1% Cover
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, 14 Fl Oz, Fresh Scent, Anti Fungal Shampoo

Nizoral Dandruff Shampoo is a powerful solution for anyone struggling with dandruff. It is clinically proven to reduce flaking, scaling, and itching, providing you relief from even the most severe cases. Unlike many other shampoos, it targets the root cause by eliminating the fungus that leads to dandruff. With its active ingredient, Ketoconazole 1%, this shampoo is ten times more effective at fighting scalp fungus than leading brands. Plus, it is gentle enough for color-treated or chemically processed hair, making it a versatile choice for your hair care routine.

What We Like
Clinically proven effectiveness
Targets root cause of dandruff
Gentle on color-treated hair
Less frequent use required
#TOP 3

Nizoral Anti-Dandruff Shampoo 1% Ketoconazole

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Nizoral Anti-Dandruff Shampoo 1% Ketoconazole Cover
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, 14 Fl Oz, Peppermint and Tea Tree Scent, Anti Fungal Shampoo, For All Hair Types

The Nizoral Ketoconazole Shampoo is designed to provide effective dandruff relief while keeping your scalp refreshed with a peppermint scent. It is specially formulated to be gentle on sensitive skin, making it suitable for both men and women. The shampoo contains 1% ketoconazole, a proven ingredient that helps reduce flaking, scaling, and itching caused by dandruff. Unlike other shampoos that only mask symptoms, this product targets the root cause by eliminating the fungus responsible for dandruff. Using this shampoo can help you maintain a healthier scalp and enjoy a clean, comfortable feeling from the first wash.

What We Like
Effective dandruff control
Peppermint scent
Gentle on sensitive scalps
Fights scalp fungus
#TOP 4

Dercos Anti Dandruff Shampoo by Vichy

Dercos Anti Dandruff Shampoo by Vichy Cover
Dercos Anti Dandruff Shampoo, Dry Scalp Treatment and Itch Relief. Prescription Strength Comparable to 2% Ketoconazole, for Mild to Severe Dandruff-Prone Hair & Flaky, Itchy Scalps, 6.76 Fl. Oz.

Vichy Dercos Anti Dandruff shampoo is designed to effectively treat dandruff and relieve dry, itchy scalps. It uses 0.6% micronized selenium sulfide, a powerful ingredient that works as well as 2% ketoconazole shampoos, helping to reduce flakes and scalp irritation. This shampoo quickly controls dandruff and soothes itching, reducing redness and discomfort for a healthier scalp. Additionally, it hydrates your hair with niacinamide and glycerin, making your hair stronger, softer, and shinier while preventing breakage. It's also safe for all hair types, including color-treated and sensitive scalps, ensuring gentle yet effective care.

What We Like
Effective dandruff control
Fast itch relief
Hydrating formula
Strengthens and softens hair
Safe for sensitive scalps
#TOP 5

Nizoral Anti-Dandruff Shampoo 1% Ketoconazole

Nizoral Anti-Dandruff Shampoo 1% Ketoconazole Cover
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, Fresh Scent, 14 Fl Oz (Pack of 2)

Nizoral Dandruff Shampoo is designed to help you effectively manage dandruff by targeting its root cause. It contains 1% Ketoconazole, a strong ingredient that fights the fungus responsible for dandruff, making it more effective than many other shampoos. This means you get relief from flaking, itching, and scaling, even if your dandruff is severe. Plus, it's clinically proven, so you can trust it to work. Using it just twice a week can keep your scalp healthy and comfortable, giving you a fresh feeling every time.

What We Like
Clinically proven effectiveness
Fights dandruff-causing fungus
Contains 1% Ketoconazole
Works on severe dandruff
Use only twice weekly
#TOP 6

Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole

20053076192685
7 Fl Oz (Pack of 3)
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole Cover
Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole, Fresh Scent, 21 Fl Oz (Pack of 3)

Nizoral Anti-Dandruff Shampoo with 1% Ketoconazole is a clinically proven dandruff treatment shampoo that helps relieve itchy and flaky scalps. It contains Ketoconazole 1%, an effective ingredient that binds to hair's natural protein to kill dandruff. This soft shampoo can be used twice a week between shampoos for a flake-free scalp. With its thick lather, it leaves hair manageable and shiny.

What We Like
Contains Ketoconazole 1%, a clinically proven ingredient that kills dandruff and keeps scalp flake-free
Thick lather and fresh scent leaves hair manageable and shiny
Can be used twice a week between shampoos for a soft and healthy scalp

Head & Shoulders Clinical Strength Dandruff Shampoo Twin Pack

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Head & Shoulders Clinical Strength Dandruff Shampoo Twin Pack Cover
Head & Shoulders Anti-Dandruff Shampoo, Clinical Strength Advanced Oil Control Twin Pack, 1% Selenium Sulfide, Seborrheic Dermatitis Relief, Oily Scalp, 13.5 fl oz Each

Head & Shoulders Clinical Strength Dandruff Shampoo Twin Pack is a powerful anti-dandruff shampoo made with 1% Selenium Sulfide for prescription strength dandruff relief and flaking protection. It provides relief from severe dandruff and seborrheic dermatitis, and is suitable for adults with oily hair. Customers have reported that it provides up to 100% dandruff protection and visible flakes with regular use, and that it relieves scalp itching and sores quickly. It also works well on Asian hair, but may leave a chemical smell after use.

What We Like
Provides up to 100% dandruff protection and visible flakes with regular use
Relieves scalp itching and sores quickly
Works well on Asian hair
#TOP 8

Nizoral Anti-Dandruff Shampoo & Conditioner Bundle

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Nizoral Anti-Dandruff Shampoo & Conditioner Bundle Cover
Nizoral Anti-Dandruff Shampoo, 14 Oz + Deep Moisturizing Conditioner, 9.4 Oz Bundle

The Nizoral Dandruff Control Set is designed to help you effectively manage dandruff and soothe your scalp. The shampoo contains Ketoconazole 1%, a strong ingredient that targets and eliminates the fungus causing dandruff, giving you relief from flaking and itching. This means you get to treat the root cause, not just the symptoms. It’s clinically proven to work even on severe dandruff, so you can trust it for reliable results. After shampooing, the deep moisturizing conditioner keeps your scalp and hair hydrated without washing away the active treatment, leaving your hair feeling soft and manageable.

What We Like
Clinically proven effectiveness
Fights root cause fungus
Contains powerful Ketoconazole 1%
Hydrating conditioner compatibility
#TOP 9

Dercos Anti Dandruff Shampoo

Dercos Anti Dandruff Shampoo Cover
Dercos Anti Dandruff Shampoo, Dry Scalp Treatment and Itch Relief. Prescription Strength Comparable to 2% Ketoconazole, for Mild to Severe Dandruff-Prone Hair & Flaky, Itchy Scalps, 13.5 Fl. Oz.

Dercos Dandruff Shampoo is designed to tackle dandruff and soothe an itchy scalp effectively. With its 0.6% micronized selenium sulfide, it directly addresses various levels of dandruff, from mild to severe. This medicated formula also includes glycerin and niacinamide, which help reduce inflammation and keep your scalp hydrated. You'll notice relief from itching after just one use. Plus, it enhances your hair's health by minimizing breakage, retaining moisture, and increasing shine, ensuring that your hair looks great while treating dandruff.

What We Like
Effective dandruff treatment
Soothes itchy scalp
Hydrates and nourishes scalp
Color safe for all hair

Head & Shoulders Clinical Strength Dandruff Shampoo

030772161647
Blue
Head & Shoulders Clinical Strength Dandruff Shampoo Cover
Head & Shoulders Dandruff Shampoo, Clinical Strength Advanced Oil Control, Our Maximum Anti-Dandruff Prescription-Strength Formula, Flake Protection, Seborrheic Dermatitis Relief, Citrus, 13.5 Fl Oz

The Head & Shoulders Clinical Shampoo offers powerful dandruff control that works faster and more effectively than regular shampoos. With advanced oil control, it helps you manage excess scalp oil and fight the fungus that causes dandruff after just one wash. This shampoo starts working twice as fast, so you can see improvement in fewer washes. Its prescription-strength formula contains 1% Selenium Sulfide, providing strong relief from flakes and protecting your scalp. Using this shampoo regularly means you can enjoy a healthier scalp without visible dandruff, making your hair feel fresh and clean all day.

What We Like
Advanced oil control
Faster dandruff relief
Prescription-strength formula
Effective flake protection
Buying Guide Image

Factors to Consider when Choosing Ketoconazole Shampoo

Active Ingredient

The active ingredient in ketoconazole shampoo is, of course, ketoconazole. Look for a shampoo that contains a sufficient concentration of ketoconazole, usually around 2%, as this is the effective dosage for treating fungal infections, such as dandruff, seborrheic dermatitis, and ringworm.

Additional Ingredients

Consider other ingredients in the shampoo that can complement the effectiveness of ketoconazole. Look for shampoos that contain soothing agents like aloe vera or tea tree oil, as they can help alleviate itching and inflammation on the scalp. Additionally, moisturizing ingredients like glycerin or coconut oil can help keep your scalp hydrated and prevent dryness.

Suitability for Hair Type

Consider your hair type when choosing a ketoconazole shampoo. Some shampoos are specifically formulated for oily hair, while others are better suited for dry or damaged hair. Ensure that the shampoo is suitable for your hair type to achieve the desired results without causing any adverse effects.

Safety and Mildness

Look for a ketoconazole shampoo that is gentle on the scalp and does not contain harsh chemicals or irritants. Avoid shampoos with sulfates, parabens, or artificial fragrances, as they can potentially strip the scalp of its natural oils and cause further irritation.

Recommendation from a Dermatologist

While it is important to consider the factors mentioned above, it is always advisable to consult a dermatologist before using any medicated shampoo. They can provide personalized recommendations based on your specific scalp condition and guide you towards the most suitable ketoconazole shampoo for your needs.

Frequently Asked Questions (FAQs)

1. What is ketoconazole shampoo good for?

Ketoconazole shampoo is used to treat dandruff and fungal infections of the skin, such as tinea versicolor. It is prescribed by doctors to address these specific conditions.

2. What happens if you use ketoconazole shampoo daily?

Using ketoconazole shampoo excessively or more often than necessary can lead to skin irritation or redness. It is important to follow the recommended usage instructions and reduce the frequency if any irritation occurs.

3. Why is ketoconazole no longer used?

Ketoconazole has been associated with liver damage, and in severe cases, it may even require liver transplantation or lead to death. Due to these risks, ketoconazole is not commonly used and alternatives are preferred.

4. Is ketoconazole 2% shampoo available over the counter?

Ketoconazole shampoo is available in both 1% and 2% concentrations. The 1% version is available over the counter, while the 2% version requires a prescription from a healthcare provider.

5. Who should not use ketoconazole shampoo?

Individuals who have had an allergic reaction to ketoconazole shampoo should discontinue its use. Pregnant or breastfeeding women should consult their doctors before using this shampoo.

6. What does ketoconazole do to hair?

In addition to treating fungal infections, ketoconazole may also help with hair loss caused by male pattern baldness. It is believed to affect the hormone DHT, which is responsible for hair loss in men.

7. How long does it take for ketoconazole shampoo to work?

Typically, you should start seeing results within two to four weeks of using ketoconazole shampoo. However, it is important to consult your doctor if you do not notice any improvement after a month.

8. Do doctors still prescribe ketoconazole?

Ketoconazole is still prescribed by doctors for the treatment of certain fungal infections on the skin that cannot be treated with topical medicine or other alternatives. It is only available by prescription.

9. What is the over the counter version of ketoconazole shampoo?

The over-the-counter version of ketoconazole shampoo is commonly known as Nizoral. It is available in most supermarkets and can be purchased online. However, for shampoos containing higher concentrations of ketoconazole, a prescription from a doctor is required.

Editor's Notes

During our ketoconazole shampoo research, we found 48 ketoconazole shampoo products and shortlisted 10 quality products. We collected and analyzed 604,391 customer reviews through our big data system to write the ketoconazole shampoo list. We found that most customers choose ketoconazole shampoo with an average price of $16.80.

The ketoconazole shampoo are available for purchase. We have researched hundreds of brands and picked the top brands of ketoconazole shampoo, including Nizoral, Dercos, Head & Shoulders. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Lisa Bechard Avatar

Lisa Bechard is a skin therapist with 12 years of working experience in the beauty industry and also an experienced beauty writer who has expertise in skincare, medical aesthetics and cosmetic surgery, and wellness. Her writing skills are excellent and all her content is very persuasive and insightful.