Best Acetaminophen for Headache of 2026

Tylenol Extra Strength Caplets are a pain reliever and fever reducer containing 500 mg acetaminophen for effective temporary relief of minor aches and pains. It is recommended for headaches, backaches, menstrual cramps, toothaches, and pain caused by the common cold. This extra strength acetaminophen pain reliever is safe when used as directed and can be used by adults and children who are 12 years and older. Tylenol is the #1 doctor recommended brand for pain relief and fever reduction.

Relieve your little one's minor aches and pains due to common cold, flu, sore throat, and toothache with Tylenol Infants Acetaminophen Medicine. Its 5-milliliter dose contains 160 milligrams of acetaminophen, which is a known pain reliever and fever reducer. It comes in a kid-friendly cherry flavor that is gentle on little tummies, and is formulated to be alcohol, aspirin, and ibuprofen-free. The package includes a SimpleMeasure dosing syringe that dispenses the proper dosage for your child's age and weight. It is recommended for children aged 2-3 years old and can also be used for teething pain in infants.

Tylenol Extra Strength Acetaminophen Rapid Release Gels come in a 100-count bottle and are designed to provide fast relief from minor aches, pains, and fever. The unique laser-drilled holes in each gelcap quickly release 500mg of acetaminophen for extra strength pain relief. This oral pain reliever is suitable for adults and children aged 12 years and older and can be used to treat headaches, toothaches, backaches, cramps, and pain caused by the common cold.

Tylenol Kids Chewables offer effective relief for your child's minor aches, pains, and cold symptoms. Each chewable tablet contains 160 mg of acetaminophen, which helps reduce fever and alleviate discomfort from headaches, sore throats, and even toothaches. The kid-friendly grape flavor makes it easy for children aged 2 to 11 to take their medicine without fuss. Plus, this formula is free from ibuprofen and aspirin, ensuring a gentle option for their tummies while providing trusted relief. With over 60 years of reliability, Tylenol is the top choice for parents seeking pediatric pain and fever solutions.

Amazon Basic Care Extra Strength Pain Relief Caplets contain Acetaminophen 500mg which is similar to Extra Strength Tylenol Caplets. It offers temporary relief for minor aches and pains caused by different factors such as toothache, headache, and backache. The product can also be used to reduce fever for adults and children aged 12 years and above. Pain can be caused by injury or illness, but the product can help ease the pain for a brief time or longer duration.

Amazon Basic Care Acetaminophen PM is a pain reliever and nighttime sleep aid that contains 500 mg of acetaminophen and 25 mg of diphenhydramine HCl in each caplet. It helps relieve minor aches and pains and promotes restful sleep for adults and children 12 years and over. The extra-strength formula is non-habit forming and contains no aspirin or gluten.

Tylenol Extra Strength Dissolve Packs feature a great tasting Berry flavor and temporarily relieve minor aches and pains due to common cold, headache, backache, muscle aches, minor pain of arthritis, menstrual cramps, and toothache. Each packet contains 500 mg of acetaminophen, a pain reliever and fever reducer, and is both ibuprofen-free and aspirin-free. This portable pain medicine dissolves in seconds on the tongue with no water needed, and is safe for both adults and children 12 years of age and older. It's a convenient form to have on hand whenever pain hits.

Tylenol Pain Reliever is a 100-count bottle of acetaminophen tablets that provides temporary relief of minor aches and pains, as well as helps reduce fever. Each tablet contains 325 mg of acetaminophen, which effectively relieves pain and has a great safety profile when used as directed. This pain reliever can be used by adults and children 6 years and older. It is ideal for alleviating common pain symptoms like headache, backache, toothache, menstrual cramps, and pain caused by the common cold. With Tylenol Pain Reliever, you can experience effective relief and get back to feeling your best. It is the #1 doctor recommended brand for pain relief and fever reduction.

Amazon Acetaminophen Pain Relief offers effective support for those dealing with minor arthritis pain. Each tablet contains 650 mg of acetaminophen, which is designed to relieve pain and reduce fever. This product is particularly useful for alleviating various discomforts, such as muscular aches, backaches, and menstrual cramps. Additionally, the extended-release formula ensures that you experience longer-lasting relief without the worry of taking multiple doses. Plus, it’s gluten-free and aspirin-free, making it a safe choice for many users. The child-resistant cap adds an extra layer of safety for households with children.