Best Acetaminophen for Back Pain of 2025

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 5, 2025

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Acetaminophen is a common pain reliever used to treat back pain. It is available over-the-counter and is often used as a first-line treatment for mild to moderate pain. Acetaminophen works by blocking the production of certain chemicals in the body that cause pain and inflammation. It is generally considered safe when used as directed, but can cause liver damage if taken in large amounts or used for long periods of time. Acetaminophen is a popular choice for those looking for a non-steroidal option to manage back pain.

At a Glance: Our Top Picks

Advil Dual Action Back Pain Caplets - 144 Count Cover #TOP 1
Advil Dual Action Back Pain Caplets - 144 Count
ftb score rating icon 9.8
Tylenol 8 Hour Muscle Aches & Pain Relief Tablets, 100 Count Cover #TOP 2
Tylenol 8 Hour Muscle Aches & Pain Relief Tablets, 100 Count
ftb score rating icon 9.7
GoodSense Dual Action Pain Relief Tablets Cover #TOP 3
GoodSense Dual Action Pain Relief Tablets
ftb score rating icon 9.5

Top 10 Acetaminophen for Back Pain

Advil Dual Action Back Pain Caplets - 144 Count

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Advil Dual Action Back Pain Caplets - 144 Count Cover
Advil Dual Action Back Pain Caplets Delivers 250mg Ibuprofen and 500mg Acetaminophen Per Dose for 8 Hours of Back Pain Relief - 144 Count

Advil Dual Action Back Pain Caplets provide 8 hours of back pain relief with a lower maximum daily dose of each medication. The medication contains 250mg Ibuprofen and 500mg Acetaminophen to fight back pain 2 ways. Acetaminophen blocks pain signals and ibuprofen targets pain caused by inflammation. It also provides relief for headache, toothache, menstrual cramp, muscle pain and lower back pain.

What We Like
Provides 8 hours of back pain relief
Fights back pain 2 ways with Ibuprofen and Acetaminophen
Relieves headache, toothache, menstrual cramp, muscle pain and lower back pain
#TOP 2

Tylenol 8 Hour Muscle Aches & Pain Relief Tablets, 100 Count

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Tylenol 8 Hour Muscle Aches & Pain Relief Tablets, 100 Count Cover
Tylenol 8 Hour Muscle Aches & Pain Acetaminophen Tablets for Muscle & Joint Pain, 100 ct

Get relief from minor aches and pains caused by muscle aches, joint pain, back pain, headache, toothache, the common cold, and menstrual cramps. Each extended-release tablet contains 650mg of acetaminophen and features two unique layers for effective pain relief that lasts up to 8 hours. These tablets reduce fever and have an excellent safety profile for adults and children over the age of 12. Tylenol is the #1 doctor recommended brand for pain relief and fever reduction.

What We Like
Provides temporary relief for minor aches and pains
Features two unique layers for effective pain relief that lasts up to 8 hours
Reduces fever and has an excellent safety profile
#TOP 3

GoodSense Dual Action Pain Relief Tablets

GoodSense Dual Action Pain Relief Tablets Cover
GoodSense Dual Action Acetaminophen and Ibuprofen (NSAID) Tablets, 250 mg/125 mg, Back Pain, 72 Count

GoodSense Pain Relief Tablets combine two effective ingredients to help you tackle pain. With 250 mg of acetaminophen and 125 mg of ibuprofen, these tablets offer powerful relief for up to eight hours. This dual-action formula is especially useful for managing back pain, giving you the comfort you need to go about your day. Designed for adults and children over 12, this pain reliever is also gluten-free, making it a convenient choice for those with dietary restrictions. Whether you're dealing with a headache or muscle aches, this product helps you feel better quickly.

What We Like
Effective dual-action formula
Long-lasting pain relief
Gluten-free option
Suitable for adults and teens
#TOP 4

GoodSense Dual Action Pain Relief Tablets

GoodSense Dual Action Pain Relief Tablets Cover
GoodSense Dual Action Acetaminophen and Ibuprofen (NSAID) Tablets, 250 mg/125 mg, Back Pain, 18 Count

GoodSense Pain Relief Tablets combine the power of two active ingredients: acetaminophen and ibuprofen. With 250 mg of acetaminophen and 125 mg of ibuprofen, these tablets offer effective relief for various pain types, including back pain. You can experience up to 8 hours of pain relief, making it easier for you to go about your day without discomfort. Designed for adults and children aged 12 and over, this formulation is also gluten-free, ensuring it fits various dietary needs. If you're looking for a dual-action pain reliever, this product can help you manage pain effectively.

What We Like
Effective dual-action formula
Long-lasting pain relief
Gluten-free option
Suitable for adults and teens
#TOP 5

GoodSense Dual Action Pain Relief Tablets

GoodSense Dual Action Pain Relief Tablets Cover
GoodSense Dual Action Acetaminophen and Ibuprofen (NSAID) Tablets, 250 mg/125 mg, Back Pain, 144 Count

GoodSense Pain Relief Tablets combine two powerful ingredients: acetaminophen and ibuprofen. This dual-action formula delivers effective relief from pain for up to eight hours, making it ideal for managing back pain and other discomforts. Designed for adults and children aged 12 and older, these tablets ensure that you can find relief when you need it most. Plus, being gluten-free means that you don’t have to worry about dietary restrictions while taking care of your pain. With this combination, you can tackle pain more effectively than with single-ingredient medications.

What We Like
Long-lasting pain relief
Dual-action formula
Gluten-free option
Suitable for adults and teens
#TOP 6

Advil Dual Action Coated Caplets

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Advil Dual Action Coated Caplets Cover
Advil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen and 500 Mg Acetaminophen Per Dose (2 Dose Equivalent) for 8 Hour Pain Relief - 216 Count

Advil Dual Action is a multi-symptom pain medication that provides relief for up to 8 hours. With a combination of ibuprofen and acetaminophen, it targets pain at the source and blocks pain signals. This pain medicine is great for headaches, toothaches, menstrual cramps, muscle pain, lower back pain, and minor aches and pains associated with arthritis. Additionally, the new packaging will feature 20% less plastic by 2022, keeping nearly 500,000 pounds of plastic out of landfills. With 216 caplets per box, Advil Dual Action is a convenient and effective solution for your pain relief needs.

What We Like
8 hour relief
Multi-symptom pain relief
Combination of ibuprofen and acetaminophen
Less plastic packaging
#TOP 7

Timely Extra Strength Headache Relief - Acetaminophen, Aspirin, Caffeine

TIME-CAP LABS, INC.
TS0417-B700ML-M1690
Timely Extra Strength Headache Relief - Acetaminophen, Aspirin, Caffeine Cover
Timely Extra Strength Headache Relief - Acetaminophen with Aspirin & Caffeine (200 Caplets) - Headache, Migraine & Back and Body Pain & Muscle Aches - Compares to Excedrin Extra Strength - Made In USA

Timely Headache Relief combines Acetaminophen, Aspirin, and Caffeine for effective management of headaches and migraines. This unique trio works together to tackle various pain aspects, providing you with a powerful solution. You will appreciate the fast-acting relief that allows you to return to your daily activities without delay. Moreover, the inclusion of caffeine enhances the effectiveness of the pain relief, making it a useful option for those who need quick help. With 200 caplets in each bottle, it’s perfect for both home use and travel, ensuring you’re always prepared for discomfort.

What We Like
Fast-acting relief
Triple-action formula
Convenient for travel
Effective for various pains
#TOP 8

Rite Aid Extra Strength Acetaminophen Caplets

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Rite Aid Extra Strength Acetaminophen Caplets Cover
Rite Aid Extra Strength Acetaminophen, 500mg - 500 Caplets | Pain Reliever & Fever Reducer for Migraines, Joint Pain, Muscle or Back Pain, and Menstrual Pain

Rite Aid Extra Strength Acetaminophen Caplets are pain relievers and fever reducers that can help relieve migraines, menstrual pain, joint and muscle pain, and arthritis pain. It contains 500mg acetaminophen, an active ingredient that effectively reduces fever and pain. The caplets' shape makes them easy to swallow, and the medicine is aspirin-free, making it ideal for those with aspirin allergies or sensitivities. Rite Aid is a trusted brand that has been providing health and wellness products since 1962.

What We Like
Effective pain and fever relief
Easy to swallow
Aspirin-free
Trusted brand
#TOP 9

Advil Dual Action

305730147187
19 Piece Set
Advil Dual Action Cover
Advil Dual Action Coated Caplets with Acetaminophen, 250 Mg Ibuprofen and 500 Mg Acetaminophen Per Dose (2 Dose Equivalent) for 8 Hour Pain Relief - 18 Count

Advil Dual Action is a powerful pain relief medication that combines the top two selling pain fighting ingredients, ibuprofen and acetaminophen. With its unique formula, this medication targets pain at the source and blocks pain signals, providing multi-symptom relief for minor aches and pains. By combining acetaminophen and ibuprofen, Advil Dual Action allows for powerful pain relief with a lower dose of each medication. As the world's #1 selling OTC pain reliever, Advil has been trusted by millions for over 30 years to provide safe and effective pain relief. Say goodbye to pain and discomfort with Advil Dual Action.

What We Like
Powerful pain relief
Multi-symptom relief
Combines top two pain fighting ingredients
#TOP 10

Goody's Back and Body Pain Relief Powder

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White
Goody's Back and Body Pain Relief Powder Cover
Goody's Back and Body Pain Relief Powder, 24 ct (Pack of 1)

Get fast relief from back and body pain with Goody's Pain Relief Powder. This dual action powder formula contains 325 mg Acetaminophen and 500 mg Aspirin (NSAID) to effectively alleviate pain. Whether you're dealing with aches from a tough workout or discomfort from everyday activities, Goody's Pain Relief Powder can provide the relief you need. With its convenient, on-the-go stick packs, you can easily take it with you anywhere for quick relief anytime. Plus, it's caffeine-free, making it suitable for those who are sensitive to caffeine. Enjoy the convenience and effectiveness of Goody's Pain Relief Powder for all your back and body pain needs.

What We Like
Fast pain relief
Dual action formula
Convenient on-the-go stick packs
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Does acetaminophen help with back pain?

During back-pain flare-ups, you may also need an over-the-counter pain reliever to help you through. Doctors often suggest you first try acetaminophen (Tylenol, others) because it is gentler on the stomach, even though NSAIDs tend to work better for back pain.

2. Which pain reliever is best for back aches?

Medicines. Ibuprofen (such as Advil or Motrin), available over-the-counter, is an excellent medication for the short-term treatment of low back pain. ... Acetaminophen (such as Tylenol) and naproxen sodium (Aleve) are also effective in relieving pain.

3. Is ibuprofen or acetaminophen better for back pain?

Some feel acetaminophen works better for them, whereas others find ibuprofen better relieves a headache. Muscle ache or pulled/strained muscle. Ibuprofen typically works better for this kind of pain relief, due to the anti-inflammatory effects.

4. Is acetaminophen a muscle relaxant?

TYLENOL® Back Pain caplets contain effective pain relief plus a muscle relaxant to relieve and relax painful back muscles....Disponibile online presso.

Editor's Notes

During our acetaminophen for back pain research, we found 24 acetaminophen for back pain products and shortlisted 10 quality products. We collected and analyzed 128,705 customer reviews through our big data system to write the acetaminophen for back pain list. We found that most customers choose acetaminophen for back pain with an average price of $11.88.

The acetaminophen for back pain are available for purchase. We have researched hundreds of brands and picked the top brands of acetaminophen for back pain, including Advil, TENA, GoodSense, TIME-CAP LABS, INC., Rite Aid. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.