Best Acetaminophen for Back Pain of 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.
Acetaminophen is a common pain reliever used to treat back pain. It is available over-the-counter and is often used as a first-line treatment for mild to moderate pain. Acetaminophen works by blocking the production of certain chemicals in the body that cause pain and inflammation. It is generally considered safe when used as directed, but can cause liver damage if taken in large amounts or used for long periods of time. Acetaminophen is a popular choice for those looking for a non-steroidal option to manage back pain.
At a Glance: Our Top Picks
Top 10 Acetaminophen for Back Pain
Advil Dual Action Back Pain Caplets - 144 Count
Advil Dual Action Back Pain Caplets provide 8 hours of back pain relief with a lower maximum daily dose of each medication. The medication contains 250mg Ibuprofen and 500mg Acetaminophen to fight back pain 2 ways. Acetaminophen blocks pain signals and ibuprofen targets pain caused by inflammation. It also provides relief for headache, toothache, menstrual cramp, muscle pain and lower back pain.
Tylenol 8 Hour Muscle Aches & Pain Relief Tablets, 100 Count
Get relief from minor aches and pains caused by muscle aches, joint pain, back pain, headache, toothache, the common cold, and menstrual cramps. Each extended-release tablet contains 650mg of acetaminophen and features two unique layers for effective pain relief that lasts up to 8 hours. These tablets reduce fever and have an excellent safety profile for adults and children over the age of 12. Tylenol is the #1 doctor recommended brand for pain relief and fever reduction.
GoodSense Dual Action Pain Relief Tablets
GoodSense Pain Relief Tablets combine two effective ingredients to help you tackle pain. With 250 mg of acetaminophen and 125 mg of ibuprofen, these tablets offer powerful relief for up to eight hours. This dual-action formula is especially useful for managing back pain, giving you the comfort you need to go about your day. Designed for adults and children over 12, this pain reliever is also gluten-free, making it a convenient choice for those with dietary restrictions. Whether you're dealing with a headache or muscle aches, this product helps you feel better quickly.
GoodSense Dual Action Pain Relief Tablets
GoodSense Pain Relief Tablets combine the power of two active ingredients: acetaminophen and ibuprofen. With 250 mg of acetaminophen and 125 mg of ibuprofen, these tablets offer effective relief for various pain types, including back pain. You can experience up to 8 hours of pain relief, making it easier for you to go about your day without discomfort. Designed for adults and children aged 12 and over, this formulation is also gluten-free, ensuring it fits various dietary needs. If you're looking for a dual-action pain reliever, this product can help you manage pain effectively.
GoodSense Dual Action Pain Relief Tablets
GoodSense Pain Relief Tablets combine two powerful ingredients: acetaminophen and ibuprofen. This dual-action formula delivers effective relief from pain for up to eight hours, making it ideal for managing back pain and other discomforts. Designed for adults and children aged 12 and older, these tablets ensure that you can find relief when you need it most. Plus, being gluten-free means that you don’t have to worry about dietary restrictions while taking care of your pain. With this combination, you can tackle pain more effectively than with single-ingredient medications.
Advil Dual Action Coated Caplets
Advil Dual Action is a multi-symptom pain medication that provides relief for up to 8 hours. With a combination of ibuprofen and acetaminophen, it targets pain at the source and blocks pain signals. This pain medicine is great for headaches, toothaches, menstrual cramps, muscle pain, lower back pain, and minor aches and pains associated with arthritis. Additionally, the new packaging will feature 20% less plastic by 2022, keeping nearly 500,000 pounds of plastic out of landfills. With 216 caplets per box, Advil Dual Action is a convenient and effective solution for your pain relief needs.
Timely Extra Strength Headache Relief - Acetaminophen, Aspirin, Caffeine
Timely Headache Relief combines Acetaminophen, Aspirin, and Caffeine for effective management of headaches and migraines. This unique trio works together to tackle various pain aspects, providing you with a powerful solution. You will appreciate the fast-acting relief that allows you to return to your daily activities without delay. Moreover, the inclusion of caffeine enhances the effectiveness of the pain relief, making it a useful option for those who need quick help. With 200 caplets in each bottle, it’s perfect for both home use and travel, ensuring you’re always prepared for discomfort.
Rite Aid Extra Strength Acetaminophen Caplets
Rite Aid Extra Strength Acetaminophen Caplets are pain relievers and fever reducers that can help relieve migraines, menstrual pain, joint and muscle pain, and arthritis pain. It contains 500mg acetaminophen, an active ingredient that effectively reduces fever and pain. The caplets' shape makes them easy to swallow, and the medicine is aspirin-free, making it ideal for those with aspirin allergies or sensitivities. Rite Aid is a trusted brand that has been providing health and wellness products since 1962.
Advil Dual Action
Advil Dual Action is a powerful pain relief medication that combines the top two selling pain fighting ingredients, ibuprofen and acetaminophen. With its unique formula, this medication targets pain at the source and blocks pain signals, providing multi-symptom relief for minor aches and pains. By combining acetaminophen and ibuprofen, Advil Dual Action allows for powerful pain relief with a lower dose of each medication. As the world's #1 selling OTC pain reliever, Advil has been trusted by millions for over 30 years to provide safe and effective pain relief. Say goodbye to pain and discomfort with Advil Dual Action.
Goody's Back and Body Pain Relief Powder
Get fast relief from back and body pain with Goody's Pain Relief Powder. This dual action powder formula contains 325 mg Acetaminophen and 500 mg Aspirin (NSAID) to effectively alleviate pain. Whether you're dealing with aches from a tough workout or discomfort from everyday activities, Goody's Pain Relief Powder can provide the relief you need. With its convenient, on-the-go stick packs, you can easily take it with you anywhere for quick relief anytime. Plus, it's caffeine-free, making it suitable for those who are sensitive to caffeine. Enjoy the convenience and effectiveness of Goody's Pain Relief Powder for all your back and body pain needs.
Frequently Asked Questions (FAQs)
1. Does acetaminophen help with back pain?
During back-pain flare-ups, you may also need an over-the-counter pain reliever to help you through. Doctors often suggest you first try acetaminophen (Tylenol, others) because it is gentler on the stomach, even though NSAIDs tend to work better for back pain.
2. Which pain reliever is best for back aches?
Medicines. Ibuprofen (such as Advil or Motrin), available over-the-counter, is an excellent medication for the short-term treatment of low back pain. ... Acetaminophen (such as Tylenol) and naproxen sodium (Aleve) are also effective in relieving pain.
3. Is ibuprofen or acetaminophen better for back pain?
Some feel acetaminophen works better for them, whereas others find ibuprofen better relieves a headache. Muscle ache or pulled/strained muscle. Ibuprofen typically works better for this kind of pain relief, due to the anti-inflammatory effects.
4. Is acetaminophen a muscle relaxant?
TYLENOL® Back Pain caplets contain effective pain relief plus a muscle relaxant to relieve and relax painful back muscles....Disponibile online presso.
During our acetaminophen for back pain research, we found 24 acetaminophen for back pain products and shortlisted 10 quality products. We collected and analyzed 128,705 customer reviews through our big data system to write the acetaminophen for back pain list. We found that most customers choose acetaminophen for back pain with an average price of $11.88.
The acetaminophen for back pain are available for purchase. We have researched hundreds of brands and picked the top brands of acetaminophen for back pain, including Advil, TENA, GoodSense, TIME-CAP LABS, INC., Rite Aid. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.