Best Probiotic Supplements for Immune Support of 2025

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Probiotic supplements are becoming increasingly popular as a means of supporting the immune system. These supplements contain live bacteria that are beneficial to the gut and can help to improve digestion and nutrient absorption. By promoting a healthy gut microbiome, probiotics can also boost the body's natural defenses against infection and disease. Some of the most popular probiotic supplements for immune support include Lactobacillus acidophilus, Bifidobacterium lactis, and Saccharomyces boulardii. These supplements are available in a variety of forms, including capsules, powders, and gummies, making them easy to incorporate into a daily routine.
At a Glance: Our Top Picks
Top 10 Probiotic Supplements for Immune Support
Nature's Bounty Ultra Strength Probiotic 10 Supplement
Boost your gut health and immune system with Nature's Bounty Ultra Strength Probiotic 10 Supplement. It contains 10 unique probiotic strains that supplement the natural diversity of your GI microbiome for overall wellness. Each capsule has 20 billion CFU of good bacteria that supports digestive health and maintains a healthy gut. The one-per-day formula is easy to follow and can be taken with a meal. This gluten-free probiotic supplement has been backed by 20 years of research and 50 years of quality, making it a reliable choice for your health needs.
Garden of Life Dr. Formulated Probiotics for Women
Garden of Life Dr. Formulated Probiotics for Women & Prebiotics is a 50 Billion CFU probiotic supplement specifically designed for women's daily digestive, vaginal, and immune health. It contains 16 probiotic strains that are shelf stable, gluten-free, dairy-free, and soy-free. It also contains organic prebiotic fiber to help feed good bacteria in the gut. Customers have reported feeling more energized and clear-headed after taking the product, as well as relief from bloating and other digestive issues.
OLLY Probiotic Gummy
OLLY Probiotic Mango Gummies are packed with one billion live cultures of bacillus coagulans, supporting your gut flora and immune system. These tasty gummies help keep your digestive tract healthy, making you feel your best. OLLY aims to simplify nutrition, ensuring you can easily maintain good health. Their gummy vitamins and supplements are not only effective but also enjoyable to consume, fitting seamlessly into your daily routine.
Culturelle Health & Wellness Daily Probiotic For Women & Men
Culturelle Health & Wellness Daily Probiotic For Women & Men is a probiotic supplement that supports your digestive health, natural immune defenses and restores the natural balance of good bacteria in your digestive tract. It is formulated with the #1 clinically studied probiotic strain, Lactobacillus rhamnosus (LGG) that has been proven to survive harsh stomach acids to reach the intestines where it is needed. The product contains 15 billion CFUs of probiotics per serving, which provides digestive and immune support. It is safe, backed by research and does not require refrigeration.
OLLY Multi + Probiotic Adult Multivitamin Gummy
OLLY Multi + Probiotic is a daily gummy vitamin for adults that provides essential nutrients to support overall health, plus a super boost of 1 billion CFUs of Probiotics to support your immune system and digestion. It contains a powerful combination of essential Vitamins and Minerals, including Biotin, for gut health. These gluten-free gummies are made with no artificial colors or flavors and come in a bright tropical fruit blend flavor.
Physician's CHOICE Probiotics 60 Billion CFU
Physician's CHOICE Probiotics is designed to enhance your digestive and gut health. With 60 billion CFU and 10 diverse probiotic strains, this supplement helps maintain a balanced microbiome, which can be beneficial for occasional issues like constipation, diarrhea, gas, and bloating. The formulation includes organic prebiotics that work in harmony with the probiotics, ensuring they thrive in your gut. Plus, the product is crafted to survive stomach acidity, maximizing the benefits for your digestive system. With third-party testing for purity and potency, you can trust that you're choosing a quality supplement.
Culturelle Women’s Healthy Balance Probiotic
Culturelle Women’s Healthy Balance Probiotic is a vegetarian probiotic supplement designed to support digestive, immune, and vaginal health. It is powered by 5 clinically proven probiotic strains, including Lactobacillus rhamnosus (LGG), which has been shown to survive harsh stomach acids to reach the intestines. It contains 15 billion CFUs of probiotics per capsule, making it a convenient daily option. This probiotic supplement is safe for pregnant women and does not require refrigeration.
Primal Harvest Primal Immune Defense Supplement
Primal Harvest Primal Immune Defense Supplement is a 3-step solution to boost your immune system, featuring high amounts of Vitamin D3, Vitamin C, Zinc, Vitamin B6, Prebiotics, Probiotics, and carefully chosen essential minerals. Besides aiding digestion, the powerful prebiotics and probiotics help maintain a strong immune response, and the product is gluten-free. The 90-day money-back policy ensures that you will be 100% satisfied with your purchase or get your money back. The product comes in a bottle with 60 capsules, providing you with the best possible immunity boost support.
VITALITOWN Probiotics 120 Billion CFUs
VITALITOWN Probiotics is a high-quality probiotic supplement that provides 120 billion CFUs and 36 strains per capsule. It is specially formulated for both men and women, offering unsurpassed quality and value. The probiotics are vegan, non-GMO, and free from common allergens such as gluten, dairy, and soy. In addition to probiotics, this supplement also contains prebiotics and digestive enzymes. These three components work together to support healthy digestion, reduce gas and bloating, and boost the immune system. The probiotics are shelf-stable and feature delayed-release technology, ensuring their survival through stomach acid and effective delivery to the intestine. Made in the USA, VITALITOWN Probiotics adhere to the highest standards of purity and potency.
Nature's Nutrition Probiotic 80 Billion CFU
Nature's Nutrition Probiotic is designed to enhance your digestive health with a potent blend of 80 billion CFU, including Lactobacillus acidophilus. This probiotic formula not only aids in maintaining a balanced gut flora but also improves nutrient absorption, which can lead to better overall health. Additionally, it supports your immune system, helping you stay strong and healthy. Specifically formulated for women, this supplement promotes healthy vaginal flora, ensuring comfort and hygiene. You can trust this non-GMO, artificial ingredient-free formula to support your wellness needs without compromise.
Frequently Asked Questions (FAQs)
1. What is the best probiotic to boost immune system?
Probiotics may help support our immune system. High-quality studies suggest that the Lactobacillus rhamnosus, LGG®, Lactobacillus paracasei, L. CASEI 431® and Bifidobacterium, BB-12® strains (hereafter referred to by use of the trademarks LGG®, L.
2. Do probiotics help boost immune system?
Probiotics may help give your immune system a boost and inhibit the growth of harmful gut bacteria ( 34 ). Also, some probiotics have been shown to promote the production of natural antibodies in the body. They may also boost immune cells like the IgA-producing cells, T lymphocytes and natural killer cells ( 35 , 36 ).
3. Are probiotics good for weak immune system?
When the gut becomes unbalanced with unhealthy levels of certain bacteria, probiotics can help restore the balance. They've been shown to secrete protective substances, which may turn on the immune system and prevent pathogens from taking hold and creating major disease.
4. Who should not take probiotics?
Some reports have linked probiotics to serious infections and other side effects. The people most likely to have trouble are those with immune system problems, people who've had surgery, and others who are critically ill. Don't take probiotics if you have any of those issues.
During our probiotic supplement for immune support research, we found 24 probiotic supplement for immune support products and shortlisted 10 quality products. We collected and analyzed 938,331 customer reviews through our big data system to write the probiotic supplements for immune support list. We found that most customers choose probiotic supplements for immune support with an average price of $19.73.
The probiotic supplements for immune support are available for purchase. We have researched hundreds of brands and picked the top brands of probiotic supplements for immune support, including Nature's Bounty, Garden of Life, OLLY, Culturelle, Physician's CHOICE. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.