Best Saccharomyces Boulardii Probiotic Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 8, 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Saccharomyces Boulardii is a type of yeast that is commonly used in probiotic supplements to support digestive health. It has been shown to help alleviate diarrhea caused by antibiotics or other gastrointestinal issues. Additionally, it may help to prevent the growth of harmful bacteria in the gut and promote the growth of beneficial bacteria. Saccharomyces Boulardii probiotic supplements are available in a variety of forms, including capsules, powders, and chewable tablets, making it easy to incorporate into your daily routine. These supplements are a great option for anyone looking to improve their digestive health and support the overall health of their gut microbiome.

At a Glance: Our Top Picks

BIOTICS Saccharomyces boulardii Probiotic Supplement Cover #TOP 1
BIOTICS Saccharomyces boulardii Probiotic Supplement
ftb score rating icon 9.8
Florastor Daily Probiotic Supplement for Digestive and Immune Support (100 Capsules) Cover #TOP 2
Florastor Daily Probiotic Supplement for Digestive and Immune Support (100 Capsules)
ftb score rating icon 9.7
Klaire Labs Saccharomyces Boulardii Probiotic Cover #TOP 3
Klaire Labs Saccharomyces Boulardii Probiotic
ftb score rating icon 9.5

Top 10 Saccharomyces Boulardii Probiotic Supplements

#TOP 1

BIOTICS Saccharomyces boulardii Probiotic Supplement

Biotics Research
LH-ECQY-8PBM
White
BIOTICS Saccharomyces boulardii Probiotic Supplement Cover
Biotics Saccharomyces boulardii Probiotic Supplement. Benefits Microbial Balance. Dairy-Free, Temperature-Stable, Supports GI Health, Supports Healthy Immune and Pathway Responses, 60 Caps

BIOTICS Saccharomyces boulardii Probiotic Supplement is a dairy-free, temperature-stable supplement that provides 4 billion CFUs per capsule. It promotes intestinal and digestive wellness by improving intestinal microbalance and can be used to help with occasional diarrhea resulting from travel or antibiotic use. Additionally, it supports healthy inflammatory pathways and the immune response by secreting soluble factors. Produced in the USA, the product is tested in a state-of-the-art laboratory to ensure safety, efficacy, and purity. It is also gluten-free.

What We Like
Contains 4 billion CFUs per capsule
Improves intestinal microbalance and promotes digestive wellness
Supports healthy inflammatory pathways and immune response
Gluten-free and dairy-free
Tested in a state-of-the-art laboratory to ensure safety, efficacy, and purity

Florastor Daily Probiotic Supplement for Digestive and Immune Support (100 Capsules)

76936
Florastor Daily Probiotic Supplement for Digestive and Immune Support (100 Capsules) Cover
Florastor Probiotics for Digestive & Immune Health, 100 Capsules, Probiotics for Women & Men, Dual Action Helps Flush Out Bad Bacteria & Boosts The Good with Our Unique Strain Saccharomyces Boulardii

Florastor Daily Probiotic Supplement is a unique probiotic with Saccharomyces boulardii lyo CNCM I-745, which helps increase the natural flora in your digestive tract and supports overall health by strengthening your digestive balance and supporting a healthy immune system. It contains 250mg of a strong probiotic strain, providing increased intestinal coverage and protection. The patented freeze-drying process gives Florastor a three-year shelf life without refrigeration, making it perfect for travelers and those with active lifestyles. The supplement is vegetarian, gluten-free, and appropriate for lactose intolerance. Florastor is an effective probiotic supplement for those who want to live a healthy lifestyle.

What We Like
Effective in boosting the body's natural production of IgA, an important antibody in your digestive system, to fight potentially harmful bacteria
Resilient probiotic formula thrives even during antibiotic use and has proven resistance to 16 of the most common oral antibiotics
Patented freeze-drying process gives Florastor a three-year shelf life without refrigeration, making it perfect for travelers and those with active lifestyles
Vegetarian, gluten-free, and appropriate for lactose intolerance
Number 1 probiotic in its class around the world, with over 65 years of use and research
#TOP 3

Klaire Labs Saccharomyces Boulardii Probiotic

9O-R0NR-FAKT
Klaire Labs Saccharomyces Boulardii Probiotic Cover
Klaire Labs Saccharomyces Boulardii Probiotic - Acid Resistant & Shelf-Stable Probiotic Supplement to Help Support Healthy Yeast Balance, Immune & Digestive Health - Hypoallergenic, Dairy-Free (120ct)

Klaire Labs Probiotic Supplement is a robust yeast-based probiotic designed to support your digestive and immune health. It is freeze-dried to ensure maximum effectiveness and longevity, so you can trust its potency. This probiotic is also resistant to acidic environments and varying temperatures, making it ideal for those with active lifestyles. Additionally, it is hypoallergenic, free from common allergens like dairy, gluten, and soy, allowing you to incorporate it into your routine without worry. This commitment to quality and safety has made Klaire Labs a trusted name among healthcare professionals since 1969.

What We Like
Acid-resistant formula
Hypoallergenic and safe
Freeze-dried for potency
Supports digestive health
#TOP 4

BioMatrix Saccharomyces Probiotic Supplement

707-01
BioMatrix Saccharomyces Probiotic Supplement Cover
Saccharomyces boulardii Probiotic Supplement w/L. paracasei, L. rhamnosus, Bifidobacterium, Acidophilus – Prebiotic Complement – Temp-Stable, 30-60 Day Supply

Experience the BioMatrix Probiotic Supplement, a reliable choice amidst the crowded probiotic market hype. Say goodbye to exaggerated claims and welcome freeze-dried strains in veggie capsules that are allergen-free and non-GMO. With patented strains like Saccharomyces boulardii and Lactobacillus paracasei, expect benefits such as gut health improvement, stress reduction, and immune support. The unique formulation ensures viability through the shelf life, offering you a convenient and effective way to support your overall well-being.

What We Like
Freeze-dried strains
Patented signature strains
High-adherence capsules
#TOP 5

Vitamatic Saccharomyces Boulardii Probiotic

810078474364
Vitamatic Saccharomyces Boulardii Probiotic Cover
Vitamatic Saccharomyces Boulardii Probiotic 10B per Serving + Yeast Extract (MOS Yeast Fraction) 300 mg - 60 DR Capsules - Made in The USA

The Vitamatic Probiotic Capsules offer a powerful blend designed to support your gut health. The DRcaps technology ensures that the ingredients are shielded from stomach acid, maximizing their effectiveness. This product is also made from premium-grade, non-GMO ingredients, ensuring you receive a quality supplement that is gluten-free. Additionally, it is free from common allergens and artificial additives, making it a safe choice for many users. Produced in a GMP-compliant and FDA-registered facility, you can trust that you are getting a reliable product for your digestive wellness.

What We Like
Stomach acid protection
Non-GMO and gluten-free
Allergen-free formulation
Manufactured in compliant facility
#TOP 6

Saccharomyces Boulardii Probiotics by Trehealtt

Trehealtt
Bld-lzx-1p-1
Saccharomyces Boulardii Probiotics by Trehealtt Cover
Saccharomyces Boulardii Probiotics 200 Billion CFUs, Clinically-Studied Probiotic for Women & Men Yeast for Intestinal, Gut, Immune & Digestive Health, Acid Resistant & Shelf-Stable, 60 Days Supply

Trehealtt Probiotics 200 Billion offers a powerful blend of Saccharomyces boulardii that supports your digestive and immune health. With 200 billion CFUs, this probiotic is designed to enhance the natural flora in your gut, promoting better digestion and a stronger immune system. Unlike many probiotics, it doesn't require refrigeration, making it convenient for on-the-go lifestyles. Additionally, its hardy nature ensures that it withstands stomach acidity, delivering maximum benefits. With a three-year shelf life, you can trust that you're getting a reliable product for your wellness needs.

What We Like
Supports digestive health
No refrigeration needed
High CFU count
Long shelf life
#TOP 7

Designs for Health FloraMyces Probiotic Capsules

Designs for Health FloraMyces Probiotic Capsules Cover
Designs for Health FloraMyces 500mg Saccharomyces Boulardii Probiotic - Gut Health Supplements - Shelf-Stable Digestive Probiotics for GI Health - Dairy-Free, Vegan Probiotic (60 Capsules)

Designs for Health FloraMyces 500mg Saccharomyces Boulardii Probiotic is a dairy-free and lactose-free probiotic supplement. Its freeze-dried, temperature-tolerant, and acid-resistant features make it a shelf-stable probiotic that does not require refrigeration. It is Non-GMO, Gluten-Free, and Vegetarian-friendly. This high-quality raw material selection supplement is the physician's choice for top quality professional strength supplements since 1989. It supports digestive health and has been voted #1 in Consumer Satisfaction in 2016 and 2017 in a Consumer Labs survey of Healthcare Practitioner Brands.

What We Like
Dairy and lactose-free probiotic supplement
Shelf-stable probiotic that does not require refrigeration
Non-GMO, Gluten-Free, and Vegetarian-friendly supplement
#TOP 8

Microbiome Labs RestorFlora PD Probiotics

10041526266
Microbiome Labs RestorFlora PD Probiotics Cover
Microbiome Labs RestorFlora PD - Daily Probiotics for Digestive Health with Saccharomyces Boulardii - Supports Gut Health & Maintains Microbial Composition (21 Capsules)

RestorFlora PD Probiotics by Microbiome Labs is designed to help you maintain a balanced gut environment, especially during or after medication use. The spore-forming strains, including Bacillus subtilis and Saccharomyces boulardii, support your immune system and digestive function. These probiotics are resilient, surviving harsh digestive conditions to deliver their benefits effectively. Plus, they are shelf-stable, making them convenient for travel. You can easily incorporate them into your routine with a simple 14-day plan to help reset your gut health.

What We Like
Supports gut health
Resilient against harsh conditions
Convenient travel-friendly packaging
Short-term usage plan
#TOP 9

DrFormulas' Nexabiotic Multi Probiotic with Saccharomyces Boulardii, Lactobacillus Acidophilus, B. infantis, Prebiotic 60 Count Capsules

DrFormulas' Nexabiotic Multi Probiotic with Saccharomyces Boulardii, Lactobacillus Acidophilus, B. infantis, Prebiotic 60 Count Capsules Cover
DrFormulas' Best Probiotics for Women & Men | Nexabiotic Multi Probiotic with Saccharomyces Boulardii, Lactobacillus Acidophilus, B. infantis, Prebiotic 60 Count Capsules (Not Pearls)

DrFormulas' Nexabiotic Multi Probiotic is an advanced and effective probiotic supplement that supports digestive health for men and women. The vegetarian plant-based Delayed Released Capsules ensure maximum probiotic efficacy with its 23 strain multi probiotic containing Saccharomyces boulardii, Lactobacillus acidophilus and 21 other probiotics with prebiotic. Each tiny easy to swallow capsule has 17.25 billion CFUs at the time of manufacture to support regular bowel movements. The diverse Hardy soil based probiotic organisms, Lactobacillus and Bifidobacterium species, diarrhea shortening Lactobacillus acidophilus and Saccharomyces boulardii probiotics provide a safe solution for the digestive health conscious. Made in the USA in a FDA inspected GMP NSF Facility.

What We Like
23 strain multi probiotic with prebiotic
Vegetarian plant-based Delayed Released Capsules ensure maximum probiotic efficacy
Each tiny easy to swallow capsule has 17.25 billion CFUs at the time of manufacture to support regular bowel movements and digestive health for men and women
Diverse probiotic organisms provide safe solution for digestive health conscious
Made in the USA in a FDA inspected GMP NSF Facility
#TOP 10

Florastor Probiotic Supplement for Immune and Digestive Support

58928
Florastor Probiotic Supplement for Immune and Digestive Support Cover
Florastor Select Immunity Boost Daily Probiotic & Immune Support Supplement for Women and Men, Saccharomyces Boulardii CNCM I-745 Plus Zinc, Vitamin C & D3 (30 Capsules)

Florastor Probiotic Supplement for Immune and Digestive Support is a daily probiotic supplement that helps increase the natural flora in your digestive tract and supports overall health by strengthening your digestive balance, actively stimulating immunity, and destroying toxins from bad bacteria. It combines the power of a unique and effective Saccharomyces boulardii lyo CNCM I-745 probiotic strain with zinc and essential vitamins your body needs to support immune health. Florastor is made with vegetarian, gluten-free, and lactose-free ingredients. It comes in a convenient box with 30 capsules that are perfect for travelers and those with active lifestyles.

What We Like
Contains a unique and effective Saccharomyces boulardii lyo CNCM I-745 probiotic strain that helps boost your body's natural production of IgA – an important antibody in your digestive system that helps fight off potentially harmful bacteria
Combines the power of probiotics with essential vitamins and minerals to support immune health, digestive balance, and overall health
Made with vegetarian, gluten-free, and lactose-free ingredients that are generally recognized as well tolerated when taken as directed
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is Saccharomyces boulardii probiotic good for?

Saccharomyces boulardii probiotic is commonly used for treating and preventing diarrhea, including rotaviral diarrhea in children. It may also be used for other types of diarrhea, acne, and digestive tract infections that can lead to ulcers. However, scientific evidence supporting its other uses is limited.

2. Is it safe to take Saccharomyces boulardii daily?

Saccharomyces boulardii is generally considered safe for most adults when taken orally for up to 15 months. However, it may cause gas in some individuals. In rare cases, it can lead to fungal infections that may spread throughout the body. It is important to consult with a healthcare provider before starting Saccharomyces boulardii.

3. What are the disadvantages of Saccharomyces boulardii?

Saccharomyces boulardii has been associated with fungal infections in individuals with digestive tract diseases. It is important to consult with a healthcare provider before starting Saccharomyces boulardii, especially if you have a weakened immune system. This probiotic supplement should be used with caution in such cases.

4. Who should not take Saccharomyces boulardii?

Individuals who are taking antifungal medications such as clotrimazole, itraconazole, ketoconazole, miconazole, nystatin, or voriconazole should not take Saccharomyces boulardii. It is important to consult with a healthcare provider to determine if this probiotic supplement is suitable for you, especially if you are taking any of these medications.

Editor's Notes

During our saccharomyces boulardii probiotic supplement research, we found 24 saccharomyces boulardii probiotic supplement products and shortlisted 10 quality products. We collected and analyzed 88,644 customer reviews through our big data system to write the saccharomyces boulardii probiotic supplements list. We found that most customers choose saccharomyces boulardii probiotic supplements with an average price of $27.93.

The saccharomyces boulardii probiotic supplements are available for purchase. We have researched hundreds of brands and picked the top brands of saccharomyces boulardii probiotic supplements, including Biotics Research, Florastor, Klaire Labs, BioMatrix, Vitamatic. The seller of top 1 product has received honest feedback from 625 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.