Best Omega-3 Probiotic Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 8, 2025

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Omega-3 probiotic supplements are a popular choice for those looking to improve their overall health and well-being. These supplements combine the benefits of omega-3 fatty acids with the power of probiotics to support digestive health, immune function, and cognitive function. Omega-3s are known for their anti-inflammatory properties and can help reduce the risk of heart disease, while probiotics promote a healthy gut microbiome and can improve digestion. Whether you're looking to support your immune system or simply want to feel your best, omega-3 probiotic supplements are a great addition to your daily routine.

At a Glance: Our Top Picks

Culturelle 3-in-1 Complete Probiotic Daily Formula Cover #TOP 1
Culturelle 3-in-1 Complete Probiotic Daily Formula
ftb score rating icon 9.8
Nextdia Butyrate Gummies with Probiotics Cover #TOP 2
Nextdia Butyrate Gummies with Probiotics
ftb score rating icon 9.7
MAV Nutrition Omega 3 Fish Oil & Probiotics Cover #TOP 3
MAV Nutrition Omega 3 Fish Oil & Probiotics
ftb score rating icon 9.5

Top 6 Omega-3 Probiotic Supplements

#TOP 1

Culturelle 3-in-1 Complete Probiotic Daily Formula

049100400389
Culturelle 3-in-1 Complete Probiotic Daily Formula Cover
Culturelle 3-in-1 Complete Probiotic Daily Formula, Once Per Day Probiotic Supplement, Helps Your Digestive System Work Better, Supports Natural Immune Defenses, Plus Omega 3's, Non-GMO, 30 Count

The Culturelle 3-in-1 Complete Probiotic Daily Formula is a probiotic supplement that offers three health benefits, including promoting heart health, improving digestive health, and supporting natural immune responses. The supplement contains 10 billion live active cultures of Lactobacillus rhamnosus GG, the #1 clinically studied probiotic, and MEG-3 Omega 3 fish oil powder, which is concentrated for potency and naturally sourced from clean, Omega 3-rich ocean fish. It comes in a convenient one-per-day capsule, making it easy to incorporate into daily wellness plans.

What We Like
Promotes heart health
Improves digestive health
Supports natural immune responses
Contains 10 billion live active cultures of Lactobacillus rhamnosus GG, the #1 clinically studied probiotic
Convenient one-per-day capsule
#TOP 2

Nextdia Butyrate Gummies with Probiotics

Nextdia Butyrate Gummies with Probiotics Cover
Butyrate Gummies with Probiotic + Prebiotic + Postbiotic, Omega-3 500mg,9 Billion CFU Probiotics with Fiber, Calcium & Magnesium, Inulin,Psyllium Husk for Digestive Health,Bloating Support,Sugar Free

The Nextdia Probiotic Butyrate Gummies offer a convenient way to support your digestive health. With a unique sugar-free formula, these gummies combine butyrate, calcium, and magnesium to enhance nutrient absorption and reduce bloating. They also contain 9 billion CFU of probiotics, which help maintain a balanced gut microbiota, promoting overall wellness. The inclusion of prebiotic fibers like inulin and psyllium husk encourages feelings of fullness, making it easier for you to manage your appetite. Plus, the algae-derived Omega-3 fatty acids work to strengthen your gut barrier, fostering a healthier digestive environment.

What We Like
Supports digestive health
Enhances nutrient absorption
Reduces bloating
Appetite control
Sugar-free and vegan
#TOP 3

MAV Nutrition Omega 3 Fish Oil & Probiotics

MAV Nutrition Omega 3 Fish Oil & Probiotics Cover
Omega 3 Fish Oil and Probiotic Capsules | Triple Strength EPA & DHA Omega 3 Burpless Softgels Plus Probiotic & Prebiotic Capsules for Gut Health & Immune Support | 60 Servings Each

MAV Omega 3 & Probiotics offers a powerful blend of fish oil and gut-supporting ingredients. Each serving provides a concentrated dose of EPA and DHA, which can enhance heart health and overall well-being. The combination of probiotics and prebiotics ensures that you not only introduce beneficial bacteria to your gut but also create an environment for them to flourish, promoting better digestion. Plus, these softgels are designed to be burpless and citrus-flavored, allowing you to enjoy the benefits of fish oil without any unpleasant aftertaste. This product could be a great addition to your daily routine for improved digestive health.

What We Like
High concentration of EPA & DHA
Supports gut health
No fishy aftertaste
Promotes healthy digestion
#TOP 4

XAVIAX Probiotics with Omega 3 for Digestive Health

XAVIAX
XAVIAX Probiotics with Omega 3 for Digestive Health Cover
XAVIAX Probiotic Gel with Omega 3 | Immune Support Supplement | Mango Flavor | to Protect The Immune System, Improves Concentration an Memory | 30 envelopes

XAVIAX Probiotics with Omega 3 is a mango-flavored bio gel that helps maintain overall digestive health, prevent occasional constipation, gas, and bloating, and protect against lactose intolerance. It contains patented live and active natural probiotics that colonize the intestines within 24 hours of ingestion, promoting improved mood, nutrition, and immune system. Enriched with agave inulin, it acts as a prebiotic for the body, and has a CFU of 1 billion. The product is certified bio gel ready-to-go, dairy-free, casein-free, and safe for ages 6 months and up.

What We Like
Contains patented live and active natural probiotics that colonize the intestines within 24 hours of ingestion, promoting improved mood, nutrition, and immune system.
Enriched with agave inulin, it acts as a prebiotic for the body, and has a CFU of 1 billion.
Certified bio gel ready-to-go, dairy-free, casein-free, and safe for ages 6 months and up.
#TOP 5

BioSchwartz Probiotic 40 Billion CFU + Omega 3 Fish Oil 90 Softgels

BioSchwartz Probiotic 40 Billion CFU + Omega 3 Fish Oil 90 Softgels Cover
Triple Strength Omega 3 Fish Oil Softgels (1 Month Supply) Plus 40 Billion CFU Daily Probiotic Supplement (1 Month Supply)

Experience the BioSchwartz Probiotic + Omega 3, a dynamic duo designed for your well-being. This product features a cutting-edge delivery system with a patented delay release for lasting relief. With lactobacillus and bifidobacterium, these probiotics support gut health. The ultra-pure fish oil contains 2,250MG per serving, enhancing brain, eye, and overall health. Plus, the professional-grade quality and enhanced absorption ensure superior standards. Take control of your health with BioSchwartz Probiotic + Omega 3.

What We Like
Cutting-edge delivery system
Professional-grade probiotics
Enhanced absorption
#TOP 6

OLLY Ultra Women's Multi Softgels & Probiotic + Prebiotic Gummy

OLLY Ultra Women's Multi Softgels & Probiotic + Prebiotic Gummy Cover
OLLY Ultra Women's Multi Softgels & Probiotic + Prebiotic Gummy, Digestive Support and Gut Health, 500 Million CFUs, Fiber, Adult Chewable Supplement for Men and Women, Peach, 30 Day Supply - 30 Count

OLLY Women's Multi Softgels offer essential nutrients for your brain, heart, immune system, and hair, skin, and nails. The B12 in these softgels supports cellular energy production, Omega-3s aid brain and eye function, and antioxidants protect against free radicals. With a daily dose of 2 softgels, these compact, mint and lemon-scented softgels are easy to swallow. The included Probiotic + Prebiotic Gummy contains 500 million CFU of Bacillus Coagulans to support a healthy digestive tract and immune system. Chew one gummy daily to nourish your good bacteria for efficient body function.

What We Like
Essential nutrients support various systems.
Convenient compact packaging.
500 million CFU for gut health.
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can I take omega-3 and probiotics together?

Combining omega 3 fatty acids with probiotics might help prevent the development of low-grade inflammation. Meanwhile, omega 3 fatty acids generate positive effects on inflammation-related conditions, such as hypertriglyceridemia and diabetes.

2. What are the dangers of taking probiotics?

Possible harmful effects of probiotics include infections, production of harmful substances by the probiotic microorganisms, and transfer of antibiotic resistance genes from probiotic microorganisms to other microorganisms in the digestive tract.

3. Is omega-3 good for gut health?

Intake of omega-3 fatty acids observed to diversify the gut microbiome. Omega-3 fatty acids have been known to lower bad cholesterol levels, improve hypertension, and improve overall heart health.

Editor's Notes

During our omega-3 probiotic supplement research, we found 24 omega-3 probiotic supplement products and shortlisted 6 quality products. We collected and analyzed 11,077 customer reviews through our big data system to write the omega-3 probiotic supplements list. We found that most customers choose omega-3 probiotic supplements with an average price of $20.69.

The omega-3 probiotic supplements are available for purchase. We have researched hundreds of brands and picked the top brands of omega-3 probiotic supplements, including Culturelle, Nextdia, MAV NUTRITION, XAVIAX, BioSchwartz. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.