Best Vegetarian Multi-Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Vegetarian multi-enzyme supplements are a popular choice for those who follow a plant-based diet. These supplements are designed to support digestion by providing a blend of enzymes that break down proteins, carbohydrates, and fats. They are made from a variety of vegetarian sources, such as papaya, pineapple, and ginger, and are free from any animal-derived ingredients. These supplements can help improve nutrient absorption, reduce bloating and gas, and promote overall digestive health. Many brands offer vegetarian multi-enzyme supplements in capsule or tablet form, making them easy to incorporate into a daily supplement routine.

At a Glance: Our Top Picks

Pure Encapsulations Digestive Enzymes Ultra Cover #TOP 1
Pure Encapsulations Digestive Enzymes Ultra
ftb score rating icon 9.8
Pure Encapsulations Digestive Enzymes Ultra Cover #TOP 2
Pure Encapsulations Digestive Enzymes Ultra
ftb score rating icon 9.7
Wholesome Wellness Digestive Enzymes Cover #TOP 3
Wholesome Wellness Digestive Enzymes
ftb score rating icon 9.5

Top 10 Vegetarian Multi-Enzyme Supplements

Pure Encapsulations Digestive Enzymes Ultra

Pure Encapsulations Digestive Enzymes Ultra Cover
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Pure Encapsulations Digestive Enzymes Ultra is a multi-enzyme supplement that supports the break down of protein, carbohydrate, fiber, and dairy*, while promoting optimal nutrient bioavailability and absorption*. The supplement contains a broad profile of digestive enzymes, providing optimal activity across a wide pH range. Pure Encapsulations uses only premium ingredients, and the product is free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Improved digestion and elimination
Reduces bloating and discomfort
Plant-based and vegetarian-friendly
Small, easy-to-swallow capsules
No allergic reactions
#TOP 2

Pure Encapsulations Digestive Enzymes Ultra

Pure Encapsulations Digestive Enzymes Ultra Cover
Pure Encapsulations Digestive Enzymes Ultra with Betaine HCl - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Pure Encapsulations Digestive Enzymes Ultra is a multi-enzyme supplement that helps support digestion and nutrient absorption. This vegetarian supplement contains a broad-spectrum combination of enzymes designed to promote optimal activity across a wide pH range. With premium ingredients and no unnecessary additives, it is formulated to facilitate the normal breakdown of proteins, polysaccharides, and disaccharides, thereby improving nutrient bioavailability and absorption.

What We Like
Improved digestion of heavy meals
Enhanced protein breakdown
Clean, allergen-free ingredients
Supports gut comfort
Trusted, reliable brand

Wholesome Wellness Digestive Enzymes

digestive-enzymes
Green
Wholesome Wellness Digestive Enzymes Cover
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

What We Like
Improved digestion and gut comfort
Reduced bloating and stomach issues
Easy-to-swallow capsules
Plant-based, organic ingredients
Supports immunity and acne control

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia

Life Extension Enhanced Super Digestive Enzymes & Probiotics

02022
White to Off White
Life Extension Enhanced Super Digestive Enzymes & Probiotics Cover
Life Extension Enhanced Super Digestive Enzymes and Probiotics – B. coagulans Probiotic, 10 Digestive Enzymes – Supports Digestion, Comfort & GI Balance – Non-GMO, Vegetarian – 60 Capsules

Life Extension Enhanced Super Digestive Enzymes & Probiotics is a vegetarian-friendly digestive health formula that helps promote digestive comfort and maintain a healthy microbiome. It contains ten types of digestive enzymes, including alpha galactosidase, protease 3.0, and lipase, as well as probiotic strand B. coagulans for comprehensive digestive support. This product is certified non-GMO and gluten-free, and is manufactured in the USA.

What We Like
Effective for bloating relief
Improves overall digestion
Contains probiotics
Recommended by health professionals
High-quality product
#TOP 6

Doctor's Best Proteolytic Enzymes

DRB-00184
No Color
Doctor's Best Proteolytic Enzymes Cover
Doctor's Best Proteolytic Enzymes, Broad Spectrum Proteolytic Enzyme Formulation, Non-GMO, Vegetarian 90 Delayed Release Veggie Caps

Doctor's Best Proteolytic Enzymes is a potent formulation containing a broad spectrum of proteolytic enzymes (proteases) to support muscle, joint, and overall tissue health. It is vegetarian, gluten-free, and Non-GMO, and comes in a 90-count veggie capsule bottle. Customers have reported positive results in terms of relief from joint and muscle pain, as well as improved gut health.

What We Like
Effective in reducing arthritis pain
Supports digestion and gut health
Helps alleviate joint discomfort
#TOP 7

American Health Chewable Multi-Enzymes, Original Papaya

043562
Orange
American Health Chewable Multi-Enzymes, Original Papaya Cover
American Health Chewable Original Papaya Enzyme 250 Chwbls

American Health Chewable Multi-Enzymes, Original Papaya supplement is designed to help with inefficient digestion and promote nutrient absorption. It is a 100% natural digestive enzyme that is useful for digestion-related issues. The vegetarian formula is great tasting and easy to consume.

What We Like
Fast digestive relief
Pleasant, sweet taste
Gentle for family use
Reduces bloating and gas
Chewable and easy to take
#TOP 8

Digestive Enzymes for Women - Multi Digestive Enzymes

Digestive Enzymes for Women - Multi Digestive Enzymes Cover
Digestive Enzymes for Women - Multi Digestive Enzymes | Papaya | Bromelain | Probiotic & Prebiotics - Gut & Digestion Support, Bloating Relief - Vegan, Lab Tested - Made in USA - 90 Capsules, One/Day

Features
10-IN-1 FULL SPECTRUM ENZYMES + PAPAIN — With Bromelain & Protease To Support Protein Digestion, Plus A Complete Blend Of 10 Enzymes Including Amylase, Lactase, And Lipase To Help Break Down Carbs, Dairy, Fats, Vegetables & Fruits For Smoother, More Complete Digestion.
DIGESTIVE ENZYMES 435mg — Advanced Enzyme Blend Designed To Support Healthy Digestion, Nutrient Absorption, And Overall Gut Comfort. Helps Your Body Naturally Break Down Food Into Usable Energy And Nutrients.
WITH PROBIOTICS & PREBIOTICS — 2 Billion CFU Of Lactobacillus Acidophilus & Bifidobacterium Lactis Support Gut Balance, While 305mg Of Prebiotics (Agave Inulin, Acacia Fiber, Black Pepper) Nourish Healthy Bacteria And Enhance Digestive & Immune Support.
TRUSTWORTHY SERVICE — At NUTRAHARMONY, Your Health Is Our Priority. From Premium Ingredient Sourcing To Precision Manufacturing, We Provide Reliable Supplements Supported By Customer-Focused Care.
PROVEN EFFECTIVENESS & MADE IN USA — Backed By Science And Manufactured In A GMP-Certified Facility In The USA To Ensure Purity, Safety, And Consistent Quality You Can Trust.
OCCASIONAL BLOATING RELIEF — Powerful Yet Gentle Digestive Support That Helps Reduce Occasional Gas & Bloating. By Breaking Down Hard-To-Digest Foods More Efficiently, This Enzyme Blend Supports Smoother Digestion, Eases Meal Heaviness, And Maintains Everyday Gut Comfort.
CARBS, PROTEINS & FATS — Targeted Enzyme Action Works Across All Major Macronutrients To Ensure Thorough Breakdown & Efficient Nutrient Release. Helps Convert Carbs Into Quick Energy, Proteins Into Essential Amino Acids, And Fats Into Usable Fuel.
#TOP 9

Source Naturals Essential Enzymes 500mg

Source Naturals Essential Enzymes 500mg Cover
Source Naturals Essential Enzymes Digestive Aid* - 500mg - 240 Capsules

Source Naturals Enzyme Supplement is a digestive aid that supports the body's natural digestive process, maximizing nutrient utilization while promoting digestive comfort. With 240 capsules per bottle, this product is a great value and each capsule should be taken with water at the beginning of each meal. This product is free of yeast, dairy, egg, gluten, soy, wheat, sugar, salt, preservatives, and artificial colors, flavors, and fragrances. Source Naturals has been a trusted brand for over 35 years, and this product is manufactured in the USA. Overall, Source Naturals Enzyme Supplement is a great choice for those looking to support their digestive health in a natural and effective way.

What We Like
Digestive aid
240 capsules per bottle
Free of common allergens
No preservatives or artificial ingredients
Trusted brand for over 35 years
#TOP 10

Pure Encapsulations Digestive Enzymes Ultra

Pure Encapsulations Digestive Enzymes Ultra Cover
Pure Encapsulations Digestive Enzymes Ultra with Betaine HCl - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 180 Capsules

Pure Encapsulations Digestive Enzymes Ultra is a vegetarian-based supplement that promotes nutrient bioavailability and absorption, facilitates normal breakdown of proteins, polysaccharides and disaccharides, and offers a broad-spectrum combination of vegetarian digestive enzymes designed to provide optimal activity across a wide pH range. Made with premium and pure ingredients, Pure Encapsulations products are free from common allergens, artificial colors, flavors, sweeteners, GMOs, and unnecessary binders, fillers, and preservatives.

What We Like
Promotes optimal nutrient bioavailability and absorption
Facilitates normal breakdown of proteins, polysaccharides, and disaccharides
Offers a broad-spectrum combination of vegetarian digestive enzymes designed for optimal activity across a wide pH range
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Are enzymes suitable for vegetarians?

Enzymes – If you see enzymes on the label, that really isn't going to tell you anything. Enzymes could refer to any type of coagulant including animal rennet. Sometimes the label will specify non-animal enzymes, which means the rennet is vegetarian-friendly.

2. What is a vegetarian enzyme?

Vegetarian Enzyme tablets are dietary supplements of fermented enzymes (suitable for vegetarians) which are specific for starches, proteins, fats, and cellulose, a dietary fiber. No animal sources.

3. What enzymes do vegans need?

1. Pure Vegan Digestive Enzyme Complex. This Pure Vegan Digestive Enzyme Complex includes all the enzymes you'll need including amylase, protease I, protease II, lactase, lipase, cellulase, maltase, and hemicellulase.

4. What are plant-based enzymes?

Plant-derived enzymes include amylase, invertase, papain, bromelain, ficin, lipoxygenase, etc. These enzymes have played an important part in food production, including syrups, bakery products, alcoholic beverages, dairy products, etc.

Editor's Notes

During our vegetarian multi-enzyme supplement research, we found 24 vegetarian multi-enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 242,644 customer reviews through our big data system to write the vegetarian multi-enzyme supplements list. We found that most customers choose vegetarian multi-enzyme supplements with an average price of $20.50.

The vegetarian multi-enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of vegetarian multi-enzyme supplements, including Pure Encapsulations, Wholesome Wellness, Garden of Life, Life Extension, Doctor's BEST. The seller of top 1 product has received honest feedback from 48,280 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.