Best Plant Based Multi-Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

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Plant-based multi-enzyme supplements are a popular choice for individuals looking to improve their digestive health. These supplements contain a blend of enzymes that aid in breaking down proteins, carbohydrates, and fats, making it easier for the body to absorb essential nutrients. Unlike animal-based enzymes, plant-based enzymes are sourced from fruits, vegetables, and other plant-based sources, making them a suitable option for vegetarians and vegans. Plant-based multi-enzyme supplements are available in various forms, including capsules, tablets, and powders, making them easy to incorporate into one's daily routine. With regular use, these supplements can help promote healthy digestion and support overall wellness.

At a Glance: Our Top Picks

Wholesome Wellness Digestive Enzymes Cover #TOP 1
Wholesome Wellness Digestive Enzymes
ftb score rating icon 9.9
Codeage Digestive Enzymes Supplement Cover #TOP 2
Codeage Digestive Enzymes Supplement
ftb score rating icon 9.8
Garden of Life Dr Formulated Digestive Enzymes Cover #TOP 3
Garden of Life Dr Formulated Digestive Enzymes
ftb score rating icon 9.6

Top 6 Plant Based Multi-Enzyme Supplements

Wholesome Wellness Digestive Enzymes

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Wholesome Wellness Digestive Enzymes Cover
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

What We Like
Improved digestion and gut comfort
Reduced bloating and stomach issues
Easy-to-swallow capsules
Plant-based, organic ingredients
Supports immunity and acne control
#TOP 2

Codeage Digestive Enzymes Supplement

Fermented Enzymes
Codeage Digestive Enzymes Supplement Cover
Codeage Fermented Digestive Enzymes Supplement 3-Month Supply - 14 Digestive Enzymes, Probiotics, Prebiotics, Fermented Botanicals, Plant-Based Multi Pancreatic Enzymes - 1 Capsule a Day - 90 Capsules

Codeage Digestive Enzymes Supplement is an all-in-one digestive enzymes solution featuring raw & vegan digestive enzymes paired with probiotics, prebiotics, fermented botanical fruits, and herbs. It contains 14 enzymes, a fermented organic botanical blend, and a probiotics blend of 4 different strains. It is made with non-GMO ingredients in the USA in a cGMP certified facility and is vegan and contains no soy, gluten, milk, egg, wheat, shellfish, color additives, or preservatives.

What We Like
Contains 14 enzymes
Organic botanical blend
Probiotics blend
Vegan & Non-GMO

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia

BiOptimizers MassZymes 4.0

MZ Parent V4
BiOptimizers MassZymes 4.0 Cover
BIOptimizers MassZymes - Complete Digestive Enzymes Supplement for Gut Health - Bloating Relief for Men and Women - Lipase Amylase Bromelain Digestive Enzymes (30 Capsules)

BiOptimizers Digestive Enzymes is a powerful digestive supplement designed to enhance your overall digestion. It contains proteolytic enzymes that help your body absorb essential amino acids, providing relief from common issues like bloating and constipation. With improved gut health, you may also feel an increase in energy and mood, allowing you to tackle your day with more focus and clarity. Additionally, this formula includes AstraZyme, which boosts nutrient absorption, aiding in faster recovery after workouts. Experience the benefits of better digestion and feel revitalized.

What We Like
Improved digestion
Increased energy levels
Enhanced mental clarity
Faster recovery
#TOP 5

Garden of Life Digestive Supplement, 180 Capsules

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Garden of Life Digestive Supplement, 180 Capsules Cover
Garden of Life 21 Powerful Digestive Enzymes with Papain, Bromelain, Lipase, Ginger, Turmeric for Complete Digestion of Protein, Carbs & Fats – Omega-Zyme ULTRA, Gluten-Free, Vegetarian, 180 Capsules

The Garden of Life Vegetarian Digestive Supplement contains 21 powerful digestive enzymes that break down difficult to digest foods and support overall digestive function. With a unique blend of enzymes optimized for all pH levels in the gastrointestinal tract, it ensures quick nutrient release by dissolving completely via UltraZorbe vegetarian capsules. This supplement is free from gluten, dairy, artificial colors, and preservatives, empowering you with extraordinary health.

What We Like
Contains 21 powerful digestive enzymes to support overall digestive function
Optimized for all pH levels throughout the gastrointestinal tract
Ensures quick nutrient release with UltraZorbe vegetarian capsules
#TOP 6

Dr. Mercola Full Spectrum Enzymes Dietary Supplement

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Dr. Mercola Full Spectrum Enzymes Dietary Supplement Cover
Dr. Mercola Full Spectrum Enzymes - 22 Different Enzymes - Supports Digestive & Immune Health - Helps Digest Carbohydrates, Fats, Proteins & Fiber - Non-GMO, Gluten-Free & Soy-Free - 90 Capsules

Dr. Mercola Full Spectrum Enzymes Dietary Supplement is formulated with 22 digestive enzymes, including four special blends to completely digest carbohydrates, fats, proteins, fibers, and more. It is gluten-free, GMO-free, and soy-free, making it safe for human consumption. The supplement is designed for real people's consumption and contains an appropriate allowance for enzyme deficiencies and loss of enzymes due to age to ensure effective digestion without waste. Each bottle contains 90 servings, and the product comes with a full 30-day money-back guarantee.

What We Like
Gluten-free, GMO-free, and soy-free
Formulated with 22 digestive enzymes
Contains an appropriate allowance for enzyme deficiencies and loss of enzymes due to age to ensure effective digestion without waste
Buying Guide Image
Editor's Notes

During our plant based multi-enzyme supplement research, we found 24 plant based multi-enzyme supplement products and shortlisted 6 quality products. We collected and analyzed 144,611 customer reviews through our big data system to write the plant based multi-enzyme supplements list. We found that most customers choose plant based multi-enzyme supplements with an average price of $23.16.

The plant based multi-enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of plant based multi-enzyme supplements, including Wholesome Wellness, Codeage, Garden of Life, BIOptimizers, Dr. Mercola. The seller of top 1 product has received honest feedback from 1,568 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.