Best Chewable Multi-Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

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Chewable multi-enzyme supplements are a popular option for individuals looking to improve their digestive health. These supplements contain a blend of enzymes that help break down food and aid in the absorption of nutrients. They are available in a variety of flavors and are designed to be taken before or after meals. Many people appreciate the convenience of chewable supplements, as they can be easily taken on-the-go. Additionally, they may be a good option for individuals who struggle to swallow pills. Chewable multi-enzyme supplements can be found at many health food stores and online retailers.

At a Glance: Our Top Picks

American Health Chewable Multi-Enzymes, Original Papaya Cover #TOP 1
American Health Chewable Multi-Enzymes, Original Papaya
ftb score rating icon 9.9
American Health Papaya Enzyme with Chlorophyll Chewable Tablets Cover #TOP 2
American Health Papaya Enzyme with Chlorophyll Chewable Tablets
ftb score rating icon 9.8
Garden of Life Dr Formulated Digestive Enzymes Cover #TOP 3
Garden of Life Dr Formulated Digestive Enzymes
ftb score rating icon 9.6

Top 10 Chewable Multi-Enzyme Supplements

#TOP 1

American Health Chewable Multi-Enzymes, Original Papaya

043562
Orange
American Health Chewable Multi-Enzymes, Original Papaya Cover
American Health Chewable Original Papaya Enzyme 250 Chwbls

American Health Chewable Multi-Enzymes, Original Papaya supplement is designed to help with inefficient digestion and promote nutrient absorption. It is a 100% natural digestive enzyme that is useful for digestion-related issues. The vegetarian formula is great tasting and easy to consume.

What We Like
Fast digestive relief
Pleasant, sweet taste
Gentle for family use
Reduces bloating and gas
Chewable and easy to take
#TOP 2

American Health Papaya Enzyme with Chlorophyll Chewable Tablets

American Health Papaya Enzyme with Chlorophyll Chewable Tablets Cover
American Health Chewable Papaya Enzyme with Chlorophyll 600 Chwbls

American Health Papaya Enzyme with Chlorophyll Chewable Tablets is a great after meal supplement that helps promote nutrient absorption and freshens breath. It is gluten free and comes in a 600 count bottle. Customers have reported that it works great for settling their tummy and avoiding indigestion. It is also a natural papaya enzyme that can be used as a minty mouth freshener.

What We Like
Promotes nutrient absorption
Freshens breath
Gluten free

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia
#TOP 4

21st Century Papaya Enzyme Chewable Tablets

P0054
No Color
21st Century Papaya Enzyme Chewable Tablets Cover
21st Century Papaya Enzyme Chewable (100 Count), Papaya & Pineapple Digestive Enzymes for Gut Health, Tropical Flavor, Non-GMO, Gluten-Free, No Added Salt, Artificial Flavors

21st Century Papaya Enzyme Chewable Tablets are a great way to support your digestive system. These chewable tablets are gluten-free, contain no added salt, yeast, preservatives, or artificial flavors, and are suitable for all stages. Customers have reported that the tablets taste good, work well, and are a great option for those with gastric bypass surgery.

What We Like
Gluten-free
No added salt, yeast, preservatives, or artificial flavors
Taste good and work well
#TOP 5

NOW ChewyZymes

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Pink W/Speckles
NOW ChewyZymes Cover
NOW Foods Supplements, ChewyZymes, Broad Spectrum Chewable Enzymes, Berry Flavor, 90 Chewables

NOW Digestive Enzymes are designed to support optimal digestion of meals. With a broad spectrum of digestive enzymes, it helps break down carbohydrates, proteins, and fats into smaller, more easily absorbed nutrients. The natural berry flavor of the vegetarian chewable tablet makes it great for both adults and kids. This supplement is also Vegan/Vegetarian, Soy Free, Keto Friendly, Dairy Free. NOW Digestive Enzymes are GMP Quality Assured. It means that every aspect of the NOW manufacturing process has been examined, including laboratory/testing methods for stability, potency, and product formulation. Customers should be available during the product delivery to avoid melting or damage of the product caused by exposure to heat or sunlight.

What We Like
Broad spectrum enzymes
Natural berry flavor
Vegan/Vegetarian/Keto Friendly
#TOP 6

Yuve Natural Papaya Digestive Enzymes

YVITPAPAYA90
Yuve Natural Papaya Digestive Enzymes Cover
Yuve Naturals Chewable Papaya Enzymes - Sugar-Free Plant-Based Digestive Enzyme Complex for Gas, Bloating & Post-Meal Comfort - Vegan, Non-GMO, Gluten-Free - 90ct

Yuve Natural Papaya Digestive Enzymes are sugar-free chewable candies that promote better digestion, aid in constipation and bloating relief, and help with detoxing and leaky gut repair. These vegan, non-GMO, and gluten-free enzymes are great for those looking to lose weight or lead an active lifestyle. Customers have reported improved digestion, reduced bloating, and increased energy levels after taking these enzymes.

What We Like
Vegan, non-GMO, and gluten-free
Promotes better digestion
Aids in constipation and bloating relief
Helps with detoxing and leaky gut repair
Customers report improved digestion, reduced bloating, and increased energy levels
#TOP 7

Carlyle Papaya Enzyme Chewable Tablets

CL4387
Carlyle Papaya Enzyme Chewable Tablets Cover
Carlyle Papaya Enzyme Chewable Tablets | Vegetarian, Non-GMO, Gluten Free Formula | Tropical Flavor

Carlyle Papaya Enzyme Chewable Tablets are a vegetarian, non-GMO, gluten-free formula with a tropical flavor. This precise blend of enzymes Protease, Amylase, Bromelain, & Lipase helps to reap the nutritional benefits of Papaya fruit. Customers have found it to be helpful for stomach upsets, heartburn, indigestion, and constipation. It is also great for rabbits!

What We Like
Vegetarian, Non-GMO, Gluten Free Formula
Tasty Tropical Chewable Tablets
Helpful for Stomach Upsets, Heartburn, Indigestion, and Constipation
#TOP 8

Klaire Labs Vital-Zymes Chewable Digestive Enzymes (180 Tablets)

SFI Health
7715
Klaire Labs Vital-Zymes Chewable Digestive Enzymes (180 Tablets) Cover
Klaire Labs SFI Health Vital-Zymes Chewable Digestive Enzymes for Adults & Kids - Enzymes for Digestion - Cherry-Flavored - May Help Reduce Occasional Gas, Bloating & Indigestion (180 Chewables)

Klaire Labs Vital-Zymes Chewable Digestive Enzymes is a multi-enzyme complex that supports the breakdown of proteins, fats, carbs, sugars & fibers. It contains a full complement of enzymes that lend maximum support for breaking down foods, including serratia peptidase, DPP-IV activity, disaccharidases and more. It is naturally cherry flavored and sweetened with xylitol, which makes it a delicious choice for children or adults who have difficulty swallowing pills. The unique formula avoids fruit enzymes, porcine and other animal-derived enzymes, and excessive amounts of proteases that may irritate GI tissues. Trusted by healthcare practitioners since 1969.

What We Like
Contains a full range of enzymes needed for optimal digestion
Naturally cherry flavored and sweetened with xylitol, making it a delicious choice for children or adults who have difficulty swallowing pills
Avoids fruit enzymes, porcine and other animal-derived enzymes, and excessive amounts of proteases that may irritate GI tissues
#TOP 9

Nature's Truth Papaya Enzyme Tablets 120 Count

Nature's Truth Papaya Enzyme Tablets 120 Count Cover
Nature's Truth Papaya Enzyme Chewable Tablets | 120 Count | Vegan, Non-GMO & Gluten Free Supplement for Digestion | Natural Tropical Flavor

Nature's Truth Papaya Enzymes offer a powerful blend of digestive aids including papain, papaya fruit, protease, and alpha amylase. These enzymes help break down proteins, fats, and carbohydrates, making digestion easier and more comfortable for you after meals. The chewable tablets come in a natural tropical flavor, providing a pleasant and convenient way to support your digestive health. Developed by a trusted family of vitamin experts, this vegan formula ensures you get high-quality ingredients without gluten, soy, or artificial additives. With Nature's Truth Papaya Enzymes, you can enjoy better digestion through a natural and reliable supplement.

What We Like
Digestive enzyme blend
Vegan and tasty chewables
Trusted family brand
Free from common allergens
#TOP 10

GNC Papaya Enzyme Chewable Tablets

GNC
093430
Chew Tab
GNC Papaya Enzyme Chewable Tablets Cover
GNC Natural Brand Papaya Enzyme, 600 chewable Tablets

The GNC Papaya Enzyme is designed to support your digestive health by providing enzymes that make digestion easier and help your body absorb important nutrients. It contains papain, an enzyme from papaya that specifically breaks down proteins, making meals easier to digest. With 600 chewable tablets, you get a convenient and tasty way to take your supplements daily. Plus, this product is made in the USA, giving you confidence in its quality. If you want a simple and effective way to support your digestion, GNC Papaya Enzyme is a great choice.

What We Like
Supports digestion
Protein digestion aid
Chewable tablets
Made in the USA
Long-lasting supply
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What do chewable enzymes do?

Assist in the breakdown of protein into constituent amino acids. Support maximum calcium, magnesium, iron, and other mineral absorption. Help to activate pancreatic enzymes. Maintain healthy gastrointestinal microbe balance and immunity.

2. Are there chewable digestive enzymes?

ChewyZymes is a broad spectrum digestive enzyme formulation in a natural berry-flavored, vegetarian chewable tablet for adults and children. It is designed to support optimal digestion of meals. * Digestive enzymes are essential to the body's absorption and full use of food.

3. What is multi enzyme good for?

This medication contains digestive enzymes, which are natural substances needed by the body to help break down and digest food. It is used when the pancreas cannot make or does not release enough digestive enzymes into the gut to digest the food.

4. Is it good to take enzyme supplements?

“Overall, a healthy person really doesn't need to take digestive enzyme supplements,” Denhard explains. “The best digestive enzymes are the ones our bodies make naturally, and they work best when you eat a whole food diet.”

Editor's Notes

During our chewable multi-enzyme supplement research, we found 24 chewable multi-enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 177,960 customer reviews through our big data system to write the chewable multi-enzyme supplements list. We found that most customers choose chewable multi-enzyme supplements with an average price of $21.55.

The chewable multi-enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of chewable multi-enzyme supplements, including American Health, Garden of Life, 21st Century, NOW Foods, Yuve. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.