Best Vegan Multi-Enzyme Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

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Vegan Multi-Enzyme Supplements are designed to support digestive health and aid in the breakdown of proteins, carbohydrates, and fats. These supplements are formulated with a blend of plant-based enzymes that work together to enhance nutrient absorption and improve digestive function. They are ideal for vegans and vegetarians who may struggle to get enough digestive enzymes from their diet. Vegan Multi-Enzyme Supplements may also be beneficial for individuals with digestive issues such as bloating, gas, and indigestion. These supplements are a convenient way to support overall digestive health and optimize nutrient absorption.

At a Glance: Our Top Picks

Pure Encapsulations Digestive Enzymes Ultra Cover #TOP 1
Pure Encapsulations Digestive Enzymes Ultra
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HUM Flatter Me Gut Health Supplement Cover #TOP 2
HUM Flatter Me Gut Health Supplement
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Pure Encapsulations Digestive Enzymes Ultra Cover #TOP 3
Pure Encapsulations Digestive Enzymes Ultra
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Top 10 Vegan Multi-Enzyme Supplements

Pure Encapsulations Digestive Enzymes Ultra

Pure Encapsulations Digestive Enzymes Ultra Cover
Pure Encapsulations Digestive Enzymes Ultra - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Pure Encapsulations Digestive Enzymes Ultra is a multi-enzyme supplement that supports the break down of protein, carbohydrate, fiber, and dairy*, while promoting optimal nutrient bioavailability and absorption*. The supplement contains a broad profile of digestive enzymes, providing optimal activity across a wide pH range. Pure Encapsulations uses only premium ingredients, and the product is free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Improved digestion and elimination
Reduces bloating and discomfort
Plant-based and vegetarian-friendly
Small, easy-to-swallow capsules
No allergic reactions
#TOP 2

HUM Flatter Me Gut Health Supplement

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HUM Flatter Me Gut Health Supplement Cover
HUM Flatter Me Digestive Enzymes for Women & Men, Digestive Health Bloating Supplement with Ginger & Peppermint Leaf, Fast Acting Anti Bloat Pills Multi Enzyme for Debloating, Vegan, 60 Capsules

HUM Flatter Me Gut Health Supplement is an anti-bloating formula, containing 18 full-spectrum digestive enzymes, ginger, peppermint leaf, and fennel seed. It helps support digestion, soothe digestion, and support nutrient absorption. Take one capsule twice daily, before your two main meals, to reduce bloating. After only one use, 80% of users felt less bloating, and users also felt as much as 2 inches less bloating, according to a clinical study.

What We Like
Reduces bloating and discomfort
Improves digestion after heavy meals
Easy to swallow capsules
Quick noticeable results
Supports regular bowel movements
#TOP 3

Pure Encapsulations Digestive Enzymes Ultra

Pure Encapsulations Digestive Enzymes Ultra Cover
Pure Encapsulations Digestive Enzymes Ultra with Betaine HCl - Vegetarian Digestive Enzyme Supplement to Support Protein, Carb, Fiber, and Dairy Digestion* - 90 Capsules

Pure Encapsulations Digestive Enzymes Ultra is a multi-enzyme supplement that helps support digestion and nutrient absorption. This vegetarian supplement contains a broad-spectrum combination of enzymes designed to promote optimal activity across a wide pH range. With premium ingredients and no unnecessary additives, it is formulated to facilitate the normal breakdown of proteins, polysaccharides, and disaccharides, thereby improving nutrient bioavailability and absorption.

What We Like
Improved digestion of heavy meals
Enhanced protein breakdown
Clean, allergen-free ingredients
Supports gut comfort
Trusted, reliable brand

Sports Research Digestive Enzymes

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Sports Research Digestive Enzymes Cover
Sports Research Digestive Enzymes with Probiotics & Ginger - Plant Based for Dairy, Protein, Sugar & Carbs - Non-GMO Verified & Vegan Friendly (90 Veggie Capsules)

Sports Research Digestive Enzymes with Probiotics and Ginger is a plant-based supplement designed to help the body properly digest proteins, fats and carbohydrates, resulting in better nutrient absorption and less digestive discomfort. It is Non-GMO Project Verified, Vegan Certified and Gluten Free. Customers have reported positive results in their digestive system since taking this supplement.

What We Like
Effective for digestive issues
High-quality ingredients
Positive customer service experience
Competitive pricing
Easy to swallow capsules

Wholesome Wellness Digestive Enzymes

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Wholesome Wellness Digestive Enzymes Cover
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

What We Like
Improved digestion and gut comfort
Reduced bloating and stomach issues
Easy-to-swallow capsules
Plant-based, organic ingredients
Supports immunity and acne control

Garden of Life Dr Formulated Digestive Enzymes

Garden of Life Dr Formulated Digestive Enzymes Cover
Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption – Organic Digest+ - Vegan, Gluten-Free, Non-GMO, Tropical Fruit Flavor, 90 Chewables

Garden of Life Dr Formulated Digestive Enzymes with Papain, Bromelain, Lipase for Digestion & Nutrient Absorption is a full spectrum plant-based enzyme formula to aid the digestion of proteins, fats, and carbs. It is Certified Organic and Non-GMO, Gluten-Free, Vegan and Carbon Neutral. It comes in a tropical flavored, shelf stable tablet that is easy to take on the go.

What We Like
Certified Organic and Non-GMO
Vegan and Carbon Neutral
Tropical flavored, shelf stable tablet
Helps with digestion after meals
Includes prebiotic fiber from Organic Acacia
#TOP 7

MaryRuth's Ultra Digestive Food Enzymes

MaryRuth's Ultra Digestive Food Enzymes Cover
MaryRuth Organics Ultra Digestive Enzymes Capsules | Up to 2 Month Supply | Supplement for Gut Health Support | Digestion & Immune Support with Amylase | Lipase & Lactase | Vegan | 60 Count

MaryRuth's Ultra Digestive Food Enzymes is a vegan supplement formulated to enable digestion, especially in those with digestive issues, amplifying nutrient absorption while reducing bloating, gas and abdominal pain. This extra strength blend of enzymes are formulated to help digest proteins, carbohydrates, fiber, fat, and lactose. It includes Protease, Amylase, Glucoamylase, Diastase, Invertase, Pectinase, Cellulase, Hemicellulase, Xylanase, Lipase, Lactase, Alpha-Galactosidase, and Beta-Glucanase. It is Non-GMO & Vegan, Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Nightshade Free, Sugar Free, and contains Maltodextrin. Customers have reported that it works great and helps reduce bloating, gas, and abdominal pain.

What We Like
Formulated to enable digestion, amplifying nutrient absorption
Extra strength blend of enzymes to help digest proteins, carbohydrates, fiber, fat, and lactose
Non-GMO & Vegan, Dairy Free, Nut Free, Gluten & Wheat Free, Soy Free, Nightshade Free, Sugar Free
#TOP 8

BIOptimizers MassZymes Digestive Enzymes

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BIOptimizers MassZymes Digestive Enzymes Cover
BIOptimizers MassZymes - Complete Digestive Enzymes Supplement for Gut Health - Bloating Relief for Men and Women - Lipase Amylase Bromelain Digestive Enzymes (120 Capsules)

BIOptimizers MassZymes Enzymes is designed to support your digestion by delivering a strong blend of enzymes that help break down proteins, fats, and carbohydrates. This can reduce bloating and improve how well your body absorbs nutrients, helping you feel lighter and more energized throughout the day. If you’re active or an athlete, it also aids in faster muscle recovery by enhancing protein breakdown, so you can bounce back quicker from workouts. Additionally, this supplement supports your gut health and immune system by easing common digestive issues like gas and indigestion, keeping your digestive tract balanced and comfortable.

What We Like
Improved digestion and less bloating
Increased energy after meals
High-quality, clean ingredients
Easy-to-swallow capsules
Supports protein absorption
#TOP 9

Life Extension Enhanced Super Digestive Enzymes & Probiotics

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Life Extension Enhanced Super Digestive Enzymes & Probiotics Cover
Life Extension Enhanced Super Digestive Enzymes and Probiotics – B. coagulans Probiotic, 10 Digestive Enzymes – Supports Digestion, Comfort & GI Balance – Non-GMO, Vegetarian – 60 Capsules

Life Extension Enhanced Super Digestive Enzymes & Probiotics is a vegetarian-friendly digestive health formula that helps promote digestive comfort and maintain a healthy microbiome. It contains ten types of digestive enzymes, including alpha galactosidase, protease 3.0, and lipase, as well as probiotic strand B. coagulans for comprehensive digestive support. This product is certified non-GMO and gluten-free, and is manufactured in the USA.

What We Like
Effective for bloating relief
Improves overall digestion
Contains probiotics
Recommended by health professionals
High-quality product
#TOP 10

Enzymedica Digest Gold + ATPro

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Enzymedica Digest Gold + ATPro Cover
Enzymedica Digest Gold + ATPro, Maximum Strength Enzyme Formula, Fast-Acting, Helps Digest Large Meals, Prevents Bloating and Gas, 90 Capsules

Enzymedica Digest Gold is a maximum strength enzyme formula that helps you beat the bloat and rediscover digestive happiness. With 14 key enzymes including amylase, protease, lipase, and lactase, this supplement works fast to break down fat, fiber, protein, and carbohydrates, all the elements in a typical meal. It contains a powerful and unique blend of bloat-busting digestive enzymes for relief of occasional bloating, gas, and indigestion. Taking one capsule before each meal lets you love what you eat again and helps prevent the uncomfortable, “too-full” feeling after eating. Enzymedica Digest Gold works throughout the entire pH spectrum in the digestive tract to remain effective in acidic and alkaline environments. It is gluten-free, milk-free, casein-free, soy-free, egg-free, and GMO-free, and is Vegan, Kosher, and Clean Label Project Certified.

What We Like
Improved digestion
Reduced bloating and discomfort
Easy to swallow capsules
Helpful for food sensitivities
Supports weight management
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Can digestive enzymes be vegan?

Yes, the majority of enzymes on the market are vegetarian and suitable for vegans. Plant-based enzymes are often more effective and gentle on the digestive tract compared to animal-derived ones.

2. What are natural vegan digestive enzymes?

Natural vegan digestive enzymes can be found in fruits like pineapple, papaya, mango, and kiwi, as well as in foods like ginger, avocado, banana, and apricot. Fermented foods like kimchi, sauerkraut, tempeh, and miso are also good sources of enzymes. These plant-based enzymes can be consumed raw or cooked.

3. What are the benefits of vegan digestive enzymes?

Vegan digestive enzyme supplements support the digestive system and aid in the absorption of nutrients. They are sourced from non-animal ingredients and help break down food, promoting better digestion and nutrient absorption.

4. Do digestive enzyme supplements really work?

While there is limited evidence to support their effectiveness for most people, digestive enzyme supplements are claimed to alleviate abdominal symptoms like bloating, gas, and bowel irregularity. However, individual results may vary.

5. Who should avoid digestive enzymes?

If you have a history of liver or gallbladder disease, stomach ulcers, or are taking medications, it is important to consult a physician before taking digestive enzyme supplements. They generally do not pose severe risks but professional advice is recommended.

6. How do vegans get gut bacteria?

A vegan diet tends to be rich in prebiotics, which are the fuel for good bacteria in the gut. Prebiotics can be found in plant foods such as apples, onions, garlic, leeks, beans, and grains. These foods support the existing beneficial bacteria in the digestive tract.

7. How do I heal my gut on a vegan diet?

To promote gut health on a vegan diet, it is recommended to: consume high-fiber foods, avoid refined sugar, stay hydrated, include plant-based probiotics, and limit the intake of fats, especially animal fats.

8. Is there a downside to taking digestive enzymes?

Some people may experience side effects from taking digestive enzyme supplements, including allergic reactions, interactions with medications, and abdominal pain. It is important to be aware of any potential side effects and consult a healthcare professional if necessary.

9. Do digestive enzymes reduce belly fat?

There is no substantial evidence to support the claim that digestive enzyme supplements reduce belly fat or aid in weight loss. Most research suggests that there are no significant weight-loss benefits associated with taking enzyme supplements.

Editor's Notes

During our vegan multi-enzyme supplement research, we found 24 vegan multi-enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 207,065 customer reviews through our big data system to write the vegan multi-enzyme supplements list. We found that most customers choose vegan multi-enzyme supplements with an average price of $20.61.

The vegan multi-enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of vegan multi-enzyme supplements, including Pure Encapsulations, HUM, Sports Research, Wholesome Wellness, Garden of Life. The seller of top 1 product has received honest feedback from 48,280 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.