Best Capsules Multi-Enzyme Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 4, 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Capsules Multi-Enzyme Supplements are a natural and effective way to support digestive health. Made with a blend of enzymes including protease, amylase, lipase, cellulase, and lactase, these capsules help break down proteins, carbohydrates, fats, fiber, and lactose. This can lead to improved digestion, reduced bloating and gas, and better absorption of nutrients. Capsules Multi-Enzyme Supplements are also gluten-free, non-GMO, and free from artificial colors and flavors. They are a convenient way to support a healthy digestive system and overall wellness.

At a Glance: Our Top Picks

NOW Supplements Super Enzymes Cover #TOP 1
NOW Supplements Super Enzymes
ftb score rating icon 9.9
NatureBell Digestive Enzymes with Probiotics Cover #TOP 2
NatureBell Digestive Enzymes with Probiotics
ftb score rating icon 9.8
Source Naturals Essential Enzymes Supplement Cover #TOP 3
Source Naturals Essential Enzymes Supplement
ftb score rating icon 9.6

Top 10 Capsules Multi-Enzyme Supplements

#TOP 1

NOW Supplements Super Enzymes

2964
Beige W/Speckles
NOW Supplements Super Enzymes Cover
NOW Foods Supplements, Super Enzymes, Formulated with Bromelain, Ox Bile, Pancreatin and Papain,180 Capsules

NOW Supplements Super Enzymes is a comprehensive blend of enzymes that supports healthy digestion. Formulated with bromelain, ox bile, pancreatin and papain, Super Enzymes helps to optimize the breakdown of fats, carbohydrates and protein. It is Soy Free, Made without Gluten, Keto Friendly and GMP Quality Assured. Customers have reported that it helps with digestive issues, bloating, slow metabolism, and acid indigestion. It is easy to swallow and comes in capsule form.

What We Like
Relieves digestive issues
Improves nutrient absorption
Recommended for pancreatic insufficiency
Easy-to-swallow capsules
Supports overall digestive health
#TOP 2

NatureBell Digestive Enzymes with Probiotics

BA-NB-DE240C
NatureBell Digestive Enzymes with Probiotics Cover
NatureBell Digestive Enzymes with Probiotics and Prebiotics, 240 Veggie Capsules | Gut & Digestive Health Support – 20 Enzyme & 5 Prebiotic Pancreatic Enzyme Complex | Non-GMO, Vegan Friendly

NatureBell Digestive Enzymes offers a comprehensive blend of digestive support in a convenient veggie capsule. With 240 capsules in a bottle, you can enjoy an 8-month supply, making it easy to incorporate into your daily routine. Each serving combines 20 digestive enzymes and 5 prebiotics, promoting better digestion and nutrient absorption. This unique formulation helps to alleviate bloating and supports overall gut health. Designed for both men and women, it aims to enhance your digestive balance and keep your gut flora thriving.

What We Like
Long-lasting 8-month supply
Supports digestion and nutrient absorption
Helps reduce bloating
Non-GMO and vegan-friendly

Source Naturals Essential Enzymes Supplement

Source Naturals Essential Enzymes Supplement Cover
Source Naturals Essential Enzymes 500mg Bio-Aligned Multiple Enzyme Supplement Herbal Defense for Digestion, Gas, Constipation & Bloating Relief - Supports A Strong Immune System - 60 Capsules

Source Naturals Essential Enzymes Supplement is a bio-aligned multiple enzyme supplement that expertly formulated to break down multiple food groups, aiding the body's natural digestive process and maximizing the body's utilization of the nutrients in the diet by helping to break down foods into smaller components that can be absorbed. It is suggested to take 1 capsule with water at the beginning of each meal (or open capsule and sprinkle over food), but not on hot food, and not exceeding 6 capsules per day. This supplement is trusted for over 35 years, manufactured in the USA, and supports a strong immune system.

What We Like
Expertly formulated to break down multiple food groups
Aids the body's natural digestive process
Maximizes the body's utilization of the nutrients in the diet by helping to break down foods into smaller components that can be absorbed

Carlyle Digestive Enzymes with 14 Probiotic Strains

CL4405
Carlyle Digestive Enzymes with 14 Probiotic Strains Cover
Carlyle Digestive Enzymes | with Probiotics & Prebiotics | 180 Capsules | Non-GMO and Gluten Free Supplement for Men & Women

Carlyle Digestive Enzymes with 14 Probiotic Strains is a non-GMO and gluten-free supplement that provides full-spectrum digestive support. It contains bromelain and comes in quick-release capsules that can be taken before or after meals. Customers have reported improved regularity and reduced bloating and stomach pain. Some customers have not seen the desired results.

What We Like
Non-GMO and gluten-free
Full-spectrum digestive support
Quick-release capsules
Improved regularity and reduced bloating and stomach pain
#TOP 5

NOW Optimal Digestive System Enzymes, 90 Veg Capsules

2958
NOW Optimal Digestive System Enzymes, 90 Veg Capsules Cover
NOW Foods Supplements, Optimal Digestive System, Full Spectrum Enzymes, 90 Veg Capsules

The NOW Optimal Digestive System Enzymes offer a blend of enzymes that will aid in the digestion of most foods, including beans and cruciferous vegetables. To maximize food utilization, it is recommended to take 2 capsules with or before each meal. This product is vegan/vegetarian, soy-free, keto-friendly and certified GMP assured. It is packaged in the USA by a family-owned company since 1968.

What We Like
Helps with bean and cabbage digestion
Offers a blend of enzymes for digestion of most foods
Vegan/vegetarian, soy-free, keto-friendly
#TOP 6

Wholesome Wellness Digestive Enzymes

digestive-enzymes
Green
Wholesome Wellness Digestive Enzymes Cover
Wholesome Wellness Digestive Enzymes 1000MG Plus Prebiotics & Probiotics Supplement, 180 Capsules, Organic Plant-Based Vegan Formula for Digestion & Lactose with Amylase & Bromelain,3-6 Months Supply

Wholesome Wellness Digestive Enzymes is a plant-based, organic supplement that helps improve digestion and gut health. With a 1000 MG dose of clinical grade digestive enzymes and a 10 billion CFU 10 strain probiotic with prebiotics, this supplement provides relief from bloating, flatulence, fat, pancreatic, and bowel cleansing. The Advanced Multi Enzyme System helps digest a variety of foods, including fried, spicy, raw, processed food, dairy, protein, salts, carb / carbohydrate, vitamin and acidic diet fruits and veggies. The supplement also contains a powerful 10 billion CFU dose of 10 different probiotic strains clinically shown to enhance preventions & immune system response.

What We Like
Relieves bloating and constipation
Plant-based vegan formula
Improves gut health
May enhance sleep, digestion, and energy
#TOP 7

Digestive Enzymes with Probiotics - Multi-Enzyme Supplement for Digestive Health

NNDigestiveEnzyme
Digestive Enzymes with Probiotics - Multi-Enzyme Supplement for Digestive Health Cover
Digestive Enzymes with Probiotics - Probiotic Multi Enzymes with Probiotics and Prebiotics for Digestive Health and Bloating Relief for Women and Men, Daily Enzymes for Gut & Digestion - 120 Capsules

Nature's Nutrition Digestive Enzymes with Probiotics is an advanced enzyme probiotic formula that supports digestion and gut health. The advanced enzyme blend replenishes digestive enzymes that may decline with age, helping to break down carbohydrates, protein, dairy, and fried foods. The proprietary Makzyme blend ensures better delivery and survivability of enzymes and probiotics. The trusted formula is third-party tested for quality and purity, and it follows strict cGMP guidelines. With bromelain as a special ingredient, this vegan and non-GMO supplement is perfect for women and men who suffer from bloating and need digestive support.

What We Like
Advanced enzyme probiotic formula supports digestion and gut health
Replenishes digestive enzymes that may decline with age
Proprietary Makzyme blend ensures better delivery and survivability of enzymes and probiotics
#TOP 8

Dr. Vitamin Multi Enzymes & Probiotics

Dr. Vitamin Multi Enzymes & Probiotics Cover
Dr. Vitamin Multi Enzymes, Pre and Probiotics for Digestive Health | 18 Active Enzymes & 1.5 Billion CFU Probiotics for Women & Men | Digestive Enzymes w/Prebiotics for Bloating Relief | 60 Capsules

Dr. Vitamin Digestive Support is designed to enhance your digestive health with a powerful combination of enzymes, probiotics, and prebiotics. This supplement features 18 active enzymes that help break down proteins, fats, and carbohydrates, making digestion smoother and reducing discomfort after meals. It also includes 19 probiotic strains and prebiotics that work together to promote a balanced gut microbiome, which can boost your immune system. Plus, its vegan and hypoallergenic formula is free from common allergens, making it suitable for those with dietary restrictions. With easy-to-swallow capsules, you can enjoy comprehensive digestive support effortlessly.

What We Like
Comprehensive digestive health support
18 active digestive enzymes
19 probiotic strains included
Vegan and hypoallergenic formula

Codeage Digestive Enzymes Supplement

Fermented Enzymes
Codeage Digestive Enzymes Supplement Cover
Codeage Fermented Digestive Enzymes Supplement 3-Month Supply - 14 Digestive Enzymes, Probiotics, Prebiotics, Fermented Botanicals, Plant-Based Multi Pancreatic Enzymes - 1 Capsule a Day - 90 Capsules

Codeage Digestive Enzymes Supplement is an all-in-one digestive enzymes solution featuring raw & vegan digestive enzymes paired with probiotics, prebiotics, fermented botanical fruits, and herbs. It contains 14 enzymes, a fermented organic botanical blend, and a probiotics blend of 4 different strains. It is made with non-GMO ingredients in the USA in a cGMP certified facility and is vegan and contains no soy, gluten, milk, egg, wheat, shellfish, color additives, or preservatives.

What We Like
Contains 14 enzymes
Organic botanical blend
Probiotics blend
Vegan & Non-GMO
#TOP 10

Piping Rock Digestive Enzymes with 14 Probiotic Strains

Piping Rock
4401a
Piping Rock Digestive Enzymes with 14 Probiotic Strains Cover
Piping Rock Digestive Enzymes with Probiotics and Prebiotics | 100 Capsules | Multi Supplement for Men & Women | 4 Billion CFU | Extra Strength Pills | Non-GMO, Gluten Free

Piping Rock Digestive Enzymes is a multi-enzyme supplement designed to support your healthy lifestyle goals. With 14 probiotic strains and 4 billion CFU, this supplement is devoted to purity, potency, and safety. Non-GMO and gluten-free, it offers superior quality nutrition at the best value. Laboratory tested, using trusted ingredients, this supplement is a great choice for those looking to improve their digestive health and overall well-being.

What We Like
14 probiotic strains
4 billion CFU
Non-GMO and gluten-free
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What do enzyme capsules do?

People diagnosed with an enzyme insufficiency often need to take prescription digestive enzymes. These supplements help the body process food and absorb nutrients better.

2. What is multi enzyme good for?

This medication contains digestive enzymes, which are natural substances needed by the body to help break down and digest food. It is used when the pancreas cannot make or does not release enough digestive enzymes into the gut to digest the food.

3. Are enzyme supplements good for you?

A lack of digestive enzymes can lead to certain health conditions, and vice versa. Taking digestive enzyme supplements is currently recommended for people with specific digestive disorders, such as pancreatic insufficiency and lactose intolerance.

4. Why you shouldn't take digestive enzymes?

Digestive enzyme supplements also could interact with antacids and certain diabetes medications. They may cause side effects including abdominal pain, gas and diarrhea.

Editor's Notes

During our capsules multi-enzyme supplement research, we found 24 capsules multi-enzyme supplement products and shortlisted 10 quality products. We collected and analyzed 189,241 customer reviews through our big data system to write the capsules multi-enzyme supplements list. We found that most customers choose capsules multi-enzyme supplements with an average price of $19.63.

The capsules multi-enzyme supplements are available for purchase. We have researched hundreds of brands and picked the top brands of capsules multi-enzyme supplements, including NOW Foods, NatureBell, Source Naturals, Carlyle, Wholesome Wellness. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.