Best Vitamin B12 Supplements for Sleep Support of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 20, 2026

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Vitamin B12 supplements are becoming increasingly popular for their potential to support healthy sleep patterns. This essential vitamin plays a key role in the production of melatonin, a hormone that regulates the sleep-wake cycle. Additionally, B12 helps to maintain healthy levels of neurotransmitters like serotonin and dopamine, which can affect mood and sleep quality. Many people choose to supplement with B12 to support their overall health and wellness, and some specifically seek out B12 supplements for sleep support. These supplements are available in a variety of forms, including capsules, gummies, and sublingual tablets.

At a Glance: Our Top Picks

Thorne Vitamin B12 Capsules Cover #TOP 1
Thorne Vitamin B12 Capsules
ftb score rating icon 9.9
Goli Apple Cider Vinegar Gummies Cover #TOP 2
Goli Apple Cider Vinegar Gummies
ftb score rating icon 9.8
Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply Cover #TOP 3
Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply
ftb score rating icon 9.6

Top 10 Vitamin B12 Supplements for Sleep Support

Thorne Vitamin B12 Capsules

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Thorne Vitamin B12 Capsules Cover
THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Healthy Sleep & Methylation* - Gluten, Dairy & Soy-Free - 60 Servings

Thorne B12 is a vitamin B12 supplement that comes in capsule form. It contains Methyl-B12, a form of vitamin B12 that is easily absorbed by the body. Thorne B12 supports heart health and nerve function, helps maintain normal circadian rhythms to support restful sleep, and supports the body's healthy methylation processes. The supplement is gluten-free, soy-free, and dairy-free. Thorne is a trusted brand, chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of U.S. Olympic Teams. With Thorne B12, you can improve your heart and nerve health, sleep better, and support your body's natural processes.

What We Like
Energy boost
Supports B12 levels
No stomach upset
Methylated form
Physician recommended

Goli Apple Cider Vinegar Gummies

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Goli Apple Cider Vinegar Gummies Cover
Goli Apple Cider Vinegar Gummies - Worlds First ACV Gummy with Vitamin B12, Beetroot & Pomegranate - Vegan, Non-GMO, Gluten-Free - 60 Count (Pack of 1)

Goli ACV Gummies offer a delicious and convenient way to incorporate the benefits of apple cider vinegar into your daily routine. Each gummy is vegan, non-GMO, gluten-free, and gelatin-free, making them suitable for various dietary preferences. Made in the USA with high-quality, locally and globally sourced ingredients, these gummies ensure you receive a reputable product. The patented formula includes essential Vitamin B12, which supports your energy levels, immune function, and overall health. With a unique flavor profile, Goli ACV Gummies make it easy to enjoy the traditional benefits of apple cider vinegar for digestion and gut health.

What We Like
Effective alternative to ACV shots
Supports digestion and energy
Vegan, gluten-free, gelatin-free
Pleasant, fresh taste
Outstanding customer service

Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply

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Pink
Nature Made Vitamin B12 Sublingual Lozenges, 150 Day Supply Cover
Nature Made Vitamin B12 1000 mcg, Easy to Take Vitamin B12 Sublingual Tablets for Energy Metabolism Support, 150 Sugar Free Fast Dissolve Tablets, 150 Day Supply

Nature Made Vitamin B12 Sublingual Lozenges provide energy metabolism support, improve brain cell function, and promote proper red blood cell formation. The 1000 mcg lozenges have a great-tasting flavor, are easy to take, and are sugar-free. This 150-day supply is perfect for vegetarians and vegans who may not consume enough B12 from their diet alone. Made in the USA with quality ingredients, these lozenges are USP Verified and the number one pharmacist recommended vitamin and supplement brand.

What We Like
Quick-dissolving sublingual tablets
Pleasant cherry flavor
Reasonable price
Reliable energy boost
Trusted quality brand

Nature’s Bounty Vitamin B12 2500 mcg Tablets

58911
Green
Nature’s Bounty Vitamin B12 2500 mcg Tablets Cover
Nature’s Bounty Vitamin B12 2500 mcg, Cellular Energy Support, for Energy Metabolism, Heart & Nervous System Health, 75 Quick Dissolve Tablets

Nature’s Bounty Vitamin B12 2500 mcg Tablets are designed to help support your body’s energy metabolism, heart and nervous system health. With 75 quick dissolve tablets, this supplement is an easy and convenient way to ensure that your body gets the Vitamin B12 that it needs. Nature's Bounty is committed to quality and safety and this supplement is gluten-free, sugar-free, and contains no artificial flavors or sweeteners, making it suitable for vegetarians.

What We Like
Quick-dissolving tablets
Pleasant cherry flavor
Boosts energy and immunity
Vegetarian-friendly formula
High-quality and affordable
#TOP 5

Nature's Bounty Vitamin B12, 1000mcg, 200 Ct

Nature's Bounty Vitamin B12, 1000mcg, 200 Ct Cover
Nature's Bounty Vitamin B12 1000 mcg Supplements, Supports Energy Metabolism, 200 Ct

Nature's Bounty B12 Tablets are a product of nearly 50 years of dedication to quality, consistency, and scientific research to make vitamins and nutritional supplements of unrivaled excellence. These tablets support cellular energy health by aiding in the conversion of food into cellular energy. They also support cardiovascular health and help maintain healthy nerves. The tablets are easy to swallow as they are coated, making them more convenient for users.

What We Like
Energy boost
Easy to take
Good value
No unpleasant aftertaste
High-quality supplement
#TOP 6

Nature Made Vitamin B12 1000 mcg Softgels

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150 Count
Nature Made Vitamin B12 1000 mcg Softgels Cover
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, B12 Vitamins 1000 mcg, 150 Softgels, 150 Day Supply

Nature Made B12 Softgels is a dietary supplement that helps support energy metabolism, brain cell function, and red blood cell formation. With 1000 mcg of Vitamin B12 per softgel, this supplement can help break down food into energy that your body can use all day long. It also supports the production of neurotransmitters needed for mood health. For vegetarians and vegans who may not consume enough B12 from diet alone, this supplement is especially important. Simply take one softgel daily with water and a meal. Nature Made B12 Softgels are gluten-free, have no synthetic dyes, and no artificial flavors. As a USP verified product and #1 Pharmacist Recommended Vitamin and Supplement Brand, you can trust the quality and effectiveness of Nature Made B12 Softgels.

What We Like
Noticeable energy boost
Easy to swallow
No aftertaste or smell
High-quality ingredients
Long-lasting supply
#TOP 7

Triquetra Health Organic Kids Methylfolate

1 Fl Oz (Pack of 1)
Triquetra Health Organic Kids Methylfolate Cover
Organic Kids L-Methylfolate + Methyl B12 Cofactor - MTHFR Sublingual Form - 5-MTHF, Superior Form of Folate - Adjustable Dosing for All Ages - Mood, Behavior, Cognition - Organic Berry Flavor, 1 Fl oz

Triquetra Kids Methylfolate offers a bioactive form of folate that your child can readily use, making it ideal for those with MTHFR gene variations. This supplement supports healthy brain development, enhancing cognitive function and focus during crucial growth years. Additionally, it helps regulate mood by balancing neurotransmitter activity, which can lead to improved emotional stability. With adjustable dosing suitable for all ages, you can easily customize the amount to fit your child's specific needs, ensuring they get the right support for their growth and learning.

What We Like
Improved focus and mood
Easy to administer
Methylated, bioavailable vitamins
Organic and clean ingredients
Kid-friendly berry flavor
#TOP 8

Nature Made Maximum Strength Vitamin B12 5000 mcg Softgels

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No Artificial Color
Nature Made Maximum Strength Vitamin B12 5000 mcg Softgels Cover
Nature Made Maximum Strength Vitamin B12 5000 mcg, Dietary Supplement for Energy Metabolism Support, 60 Softgels, 60 Day Supply

Nature Made Maximum Strength Vitamin B12 5000 mcg Softgels is a dietary supplement that supports energy metabolism and brain cell function. It contains high-quality ingredients, is gluten-free and has no artificial flavors or preservatives. This supplement is essential for vegetarians and vegans who may not consume enough vitamin B12 from their diet alone. It is recommended to take one softgel daily with water and a meal for a 60-day supply.

What We Like
Easy to swallow
No taste
Small size
High vitamin quality
Affordable price

Pure Encapsulations B-Complex Plus Supplement

Pure Encapsulations B-Complex Plus Supplement Cover
Pure Encapsulations B-Complex Plus - B Vitamins Supplement to Support Neurological Health, Cardiovascular Health, Energy Levels & Nervous System Support* - with Vitamin B12 & More - 120 Capsules

The Pure Encapsulations B-Complex Plus Supplement is designed to support your nervous system, cognitive function, and cellular energy. It contains methylated folate and vitamin B12 to promote healthy nerve and blood cells, memory, and energy levels. The B vitamins in the supplement help convert carbohydrates into energy and support protein metabolism. The product is made with premium ingredients and tested for purity, and it is free from harmful additives such as gluten, artificial colors, flavors, and sweeteners.

What We Like
Clean, high-quality formulation
Supports energy and reduces fatigue
Gentle on stomach
Supports neurological and nerve health
No unnecessary fillers or allergens

Horbaach B12 Sublingual Methylcobalamin 5000mcg

CL1171
Horbaach B12 Sublingual Methylcobalamin 5000mcg Cover
Horbäach B12 Vitamin 5000 mcg | 120 Fast Dissolve Tablets | Sublingual Methylcobalamin | Vegetarian, Non-GMO & Gluten Free Supplement

Horbaach B12 Sublingual is a vitamin B12 supplement that comes in delicious natural berry flavor. Each fast dissolve tablet features a potent formula of 5000mcg vitamin B12 as methylcobalamin. The vegetarian formula is expertly crafted, backed by a commitment to purity and potency. The product is naturally free of gluten, yeast, milk, lactose, artificial flavoring, and non-GMO. The sublingual form of B12 ensures easy absorption by placing it under your tongue. This supplement can be beneficial for those who have a deficiency in vitamin B12, which can help improve energy levels, brain function, and support a healthy nervous system. The fast dissolve tablet is also convenient to take on-the-go, making it easy to maintain your daily B12 intake.

What We Like
Good taste
Quick dissolution
Value for price
Positive health impact
Fast delivery
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Will vitamin B12 help me sleep?

It has been found that the vitamin works directly on the brain to help induce sleep. Vitamin B12 benefits have been demonstrated to help patients with sleep disorders, such as insomnia, who have difficulty falling asleep. It has also been shown to improve sleep in healthy individuals depending on the dose that is used.

2. Is it OK to take B12 before bed?

As a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.

3. Can B12 supplements cause sleep problems?

Some studies show a connection between low vitamin B12 and insomnia, while other studies show higher levels of vitamin B12 are linked to sleep disruption and shorter sleep times.

Editor's Notes

During our vitamin b12 supplement for sleep support research, we found 24 vitamin b12 supplement for sleep support products and shortlisted 10 quality products. We collected and analyzed 2,281,017 customer reviews through our big data system to write the vitamin b12 supplements for sleep support list. We found that most customers choose vitamin b12 supplements for sleep support with an average price of $17.56.

The vitamin b12 supplements for sleep support are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b12 supplements for sleep support, including THORNE, Goli, Nature Made, Nature's Bounty, Triquetra Health. The seller of top 1 product has received honest feedback from 90 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.