Best 5-HTP Supplements for Sleep Support of 2026

The Natural Factors L-Theanine supplement is designed to help you stay calm and relaxed without making you feel sleepy. It supports better sleep quality, helping you enjoy more restful nights so you can wake up refreshed and ready for the day. You can take 1 to 2 chewable tablets up to three times daily, making it easy to fit into your routine. Plus, it’s made without common allergens like dairy, gluten, soy, and nuts, so it’s a safe choice for many people seeking natural calming support.

Doctor's Best L-Theanine is a high-quality supplement that contains Suntheanine, a pure form of L-Theanine. L-Theanine is known for its ability to promote a healthy mood and a relaxed state while maintaining daytime alertness. This amino acid found naturally in tea supports relaxation, focus, and memory without causing drowsiness. It also supports brain health by enhancing cognitive performance and alertness. Additionally, L-Theanine may help improve the quality of sleep, concentration, and learning performance. With its ability to reduce stress and support mental tranquility, Doctor's Best L-Theanine is a great addition to your daily routine.

Triquetra Health’s Organic 5-HTP Capsules are a natural solution to promote a calm and relaxed mood, better quality sleep, and mental cognition. Derived from organic Griffonia Seeds and extracted using the purest water extraction method, this 5-HTP supplement has a 99% purity and concentration of 5-HTP, making it 10 times more potent than other leading 5-HTP products on Amazon. The formula is enhanced with vitamin B6 and organic Lions Mane, aiding in the 5-HTP to serotonin conversion process and cognition enhancement properties, respectively. Each serving of 2 capsules provides 200 mg of 5-HTP and 10 mg of Vitamin B6, clinically validated for effectiveness.

The Thorne 5-HTP supplement is a great addition to your daily routine. This supplement offers support for restful sleep, nutritional support for stress, helps decrease sugar cravings, and supports a healthy outlook. With Thorne being chosen by champions and trusted by 100+ pro teams, it's no wonder they are the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. This supplement also offers hypoallergenic benefits and is perfect for adults looking for a natural solution to support their sleep and stress management.

The DR EMIL NUTRITION 200 MG 5-HTP Plus Formula is a natural supplement that supports mood, stress, and sleep. This formula contains 200mg of pure 5-HTP supplemented with 20mg of SAMe and 20mg of L Tryptophan to optimize 5-HTP conversion and support stress levels in the body. It also contains vitamin B6 for improved 5-HTP conversion. Vitamin B6 has been shown to aid 5-HTP conversion, and this formula has enough to ensure efficacy. This product is vegan and promotes calm and relaxation, making it a natural way to support a calm and relaxed mood by supporting 5-HTP conversion in the body.

Improve your mood and relaxation with the NOW Supplements 5-HTP 100mg Veg Capsules, which are vegan and support the production of serotonin in the brain and central nervous system. These capsules can impact sleep, mood, appetite, and body temperature. The Griffonia Simplicifolia extract in these capsules helps to extract the intermediate metabolite between the amino acid L-tryptophan and serotonin. The product is GMP Quality Assured, non-GMO, and packaged in the USA by a family-owned company since 1968.

Double Wood's 5HTP Liquid Drops are a unique and effective serotonin supplement that is more absorbable than encapsulated 5 HTP products. With over 99% 5-HTP, Double Wood offers the first maximum absorption 5 HTP drops. This product may help support mood and nighttime relaxation. A bottle contains 60 servings of our 5 HTP supplement per bottle in a convenient dropped format, which is a two-month supply. The 5 HTP drops capsules are manufactured and tested in the USA, Gluten-Free, and Non-GMO.

The SNAC ZMA-5 Sleep Aid is designed to help you train hard and recover better by supporting restful sleep and muscle growth. It combines zinc, magnesium, vitamin B6, and 5-HTP to promote deeper, more restorative sleep, which helps your body repair tissues and build muscle effectively. This supplement is free from gluten, GMOs, and animal ingredients, making it a clean choice for your health. Trusted by professional athletes like boxing champions, SNAC ZMA-5 Sleep Aid helps you maximize your workout recovery and boost your immune system, so you can feel stronger and more energized every day.

Arazo Nutrition 5-HTP 200mg is a highly potent supplement that contains 99% high purity 5-Hydroxytryptophan. The extra 328mg of Calcium per serving enhances deeper and longer sleep, promotes greater tranquility and calmness, and boosts immediate positive mood and sleep support. It is made in a GMP certified facility in America and third party safety tested for purity. With 120 capsules, each serving is 200mg, and 100mg per capsule of 5-HTP, this supplement provides a 60 days supply.

Natrol Cognium Memory is designed to support your brain health by protecting your neurons from damage caused by oxidative stress. This supplement includes a natural protein derived from silkworm cocoons, known for its strong research backing in improving memory. By taking this product, you can expect enhanced mental performance, helping you think more clearly and stay sharp. Additionally, it supports better memory and recall within just a few weeks, making it a convenient choice for those wanting to boost their cognitive function effectively.