Best 5-HTP Supplements for Sleep Support of 2025

The DR EMIL NUTRITION 200 MG 5-HTP Plus Formula is a natural supplement that supports mood, stress, and sleep. This formula contains 200mg of pure 5-HTP supplemented with 20mg of SAMe and 20mg of L Tryptophan to optimize 5-HTP conversion and support stress levels in the body. It also contains vitamin B6 for improved 5-HTP conversion. Vitamin B6 has been shown to aid 5-HTP conversion, and this formula has enough to ensure efficacy. This product is vegan and promotes calm and relaxation, making it a natural way to support a calm and relaxed mood by supporting 5-HTP conversion in the body.

Double Wood's 5HTP Liquid Drops are a unique and effective serotonin supplement that is more absorbable than encapsulated 5 HTP products. With over 99% 5-HTP, Double Wood offers the first maximum absorption 5 HTP drops. This product may help support mood and nighttime relaxation. A bottle contains 60 servings of our 5 HTP supplement per bottle in a convenient dropped format, which is a two-month supply. The 5 HTP drops capsules are manufactured and tested in the USA, Gluten-Free, and Non-GMO.

NatureWise 5-HTP Plus+ is a plant-based supplement that helps promote healthy eating habits, particularly carbs and sugars, which can aid in maintaining a healthy diet. It delivers a potent 200 mg dose of 5-HTP enhanced with vitamin B6 for better absorption and effectiveness. The delayed release capsules are easier on the stomach, minimizing discomfort that higher doses of 5-HTP can cause. Our supplement is naturally derived from the seeds of the Griffonia plant, and is non-GMO, gluten-free, vegan, and contains no artificial fillers. Some studies have suggested that 5-HTP may have a role in promoting a healthy weight by supporting cravings habits.

Experience relaxation, stress relief, and better sleep with Purely Optimal 5-HTP+ Complex Supplement. It contains 250mg of 5-HTP plus herbal extracts and amino acids that boost cognitive function, and vitamins and minerals for overall body support. The supplement helps boost melatonin production to regulate sleep-wake cycle, leading to better sleep quality. Made in the USA in a GMP certified facility, the product is 3rd party lab tested for safety and quality. Each purchase also contributes to life-saving vitamins and minerals for children and mothers in need through a partnership with Vitamin Angels.

The Thorne 5-HTP supplement is a great addition to your daily routine. This supplement offers support for restful sleep, nutritional support for stress, helps decrease sugar cravings, and supports a healthy outlook. With Thorne being chosen by champions and trusted by 100+ pro teams, it's no wonder they are the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. This supplement also offers hypoallergenic benefits and is perfect for adults looking for a natural solution to support their sleep and stress management.

Arazo Nutrition 5-HTP 200mg is a highly potent supplement that contains 99% high purity 5-Hydroxytryptophan. The extra 328mg of Calcium per serving enhances deeper and longer sleep, promotes greater tranquility and calmness, and boosts immediate positive mood and sleep support. It is made in a GMP certified facility in America and third party safety tested for purity. With 120 capsules, each serving is 200mg, and 100mg per capsule of 5-HTP, this supplement provides a 60 days supply.

Triquetra Health’s Organic 5-HTP Capsules are a natural solution to promote a calm and relaxed mood, better quality sleep, and mental cognition. Derived from organic Griffonia Seeds and extracted using the purest water extraction method, this 5-HTP supplement has a 99% purity and concentration of 5-HTP, making it 10 times more potent than other leading 5-HTP products on Amazon. The formula is enhanced with vitamin B6 and organic Lions Mane, aiding in the 5-HTP to serotonin conversion process and cognition enhancement properties, respectively. Each serving of 2 capsules provides 200 mg of 5-HTP and 10 mg of Vitamin B6, clinically validated for effectiveness.

Doctor's Best Sleep Formula offers a powerful blend of ingredients like Ashwagandha, 5-HTP, and L-Theanine, designed to help you relax and support a healthy sleep cycle. This combination works to improve your sleep quality and duration, allowing you to stay asleep longer and restore your natural sleep rhythm. Additionally, the formula promotes a better mood and reduces feelings of stress and irritability, enhancing your overall energy levels. With its vegan, non-GMO, and gluten-free attributes, you can enjoy a restful night's sleep without any dietary concerns.

NUTRAHARMONY 5HTP Capsules offer a powerful blend designed to enhance your mood and support restful sleep. With 400mg of 5-HTP, this supplement helps you maintain a positive outlook and balance in your daily life. The unique formula also includes Ashwagandha and L-Theanine, which promote relaxation and cognitive function. Additionally, Vitamins B6 and D3 in the mix contribute to overall brain health. Made in the USA with high-quality, globally sourced ingredients, you can trust that each capsule is crafted for your well-being.

Integrative 5-HTP Support offers nutritional assistance for achieving restful sleep and a positive mindset. This supplement contains 5-HTP, which is essential for serotonin production, helping you maintain a balanced mood and better sleep patterns. Sourced from the seeds of the Griffonia simplicifolia plant, this product ensures quality and effectiveness. Additionally, it is gluten-free and vegan, making it suitable for various dietary preferences. By choosing this supplement, you can enjoy the benefits of improved sleep and a brighter outlook on life.