Best Vitamin B12 Supplements for Immune Support of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 8, 2025

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Vitamin B12 supplements are a popular choice for those looking to boost their immune system. This essential vitamin plays a crucial role in the production of red blood cells and DNA, as well as supporting healthy nerve function. While many foods contain B12, such as meat, fish, and dairy, some individuals may struggle to get enough through their diet alone. Vitamin B12 supplements come in various forms, including capsules, tablets, and even gummies, making it easy to incorporate into your daily routine. With regular use, these supplements can help support a healthy immune system, improve energy levels, and promote overall well-being.

At a Glance: Our Top Picks

Pure Encapsulations B12 Liquid Cover #TOP 1
Pure Encapsulations B12 Liquid
ftb score rating icon 9.8
Amazon Solimo Vitamin B12 Gummies Cover #TOP 2
Amazon Solimo Vitamin B12 Gummies
ftb score rating icon 9.7
MaryRuth Organics Vitamin D3 + B12 Gummies Cover #TOP 3
MaryRuth Organics Vitamin D3 + B12 Gummies
ftb score rating icon 9.5

Top 10 Vitamin B12 Supplements for Immune Support

Pure Encapsulations B12 Liquid

B12L
1 Fl Oz (Pack of 1)
Pure Encapsulations B12 Liquid Cover
Pure Encapsulations B12 Liquid | 1,000 mcg Vitamin B12 (Methylcobalamin) Supplement to Support Nerves, Immune Health, Energy, and Cognitive Function* | 1 fl. oz.

Pure B12 Liquid is a premium quality vitamin B12 supplement from Pure Encapsulations. It contains 1,000 mcg of methylcobalamin, a form of B12 that is more easily absorbed by the body. B12 is essential for nerve cell health and cognitive function, and can also play an important role in energy production and immune system health. Pure B12 Liquid is made with only the highest quality ingredients, and is free from common allergens and unnecessary fillers and preservatives.

What We Like
Premium quality
Highly absorbable form
Supports nerve cell health

Amazon Solimo Vitamin B12 Gummies

Amazon Basics
SMARA-HPC-7238
Amazon Solimo Vitamin B12 Gummies Cover
Amazon Basics Vitamin B12 3000 mcg Gummies, Normal Energy Production and Metabolism, Immune System Support, Raspberry, 100 Count (2 per serving) (Previously Solimo)

The Amazon Solimo Vitamin B12 Gummies support energy production and metabolism and promote healthy immune function, while also aiding in normal brain function and cognition. The raspberry flavored vegan gummies come with 100 gummies per bottle, enough for a one-and-a-half month supply when taken daily at listed serving size. The gummies are gluten-free, and do not contain wheat, dairy, soy, or egg.

What We Like
Supports energy production and metabolism
Promotes healthy immune function
100 gummies per bottle, enough for a one-and-a-half month supply
Gluten-free, free of wheat, dairy, soy, and egg
Refund available for any reason within a year of purchase

MaryRuth Organics Vitamin D3 + B12 Gummies

MaryRuth Organics Vitamin D3 + B12 Gummies Cover
MaryRuth Organics Vegan Vitamin D3 + Vitamin B12 Gummies | 2 Month Supply | Supports Bone Health | Immune Support Supplement | Energy Supplements | Methyl B12 Vegan Non-GMO Gluten Free | 60 Servings

Looking for an easy and tasty way to supplement your vitamin D and B12? MaryRuth Organics Vitamin D3 + B12 Gummies are the perfect solution. Made from wild-crafted lichen and methylcobalamin, these vegan gummies support cellular health and neurofunction, while also promoting energy boosts. Vitamin D3 aids in calcium absorption and immune function, while B12 supports DNA synthesis and red cell production. With 60 servings per bottle, these gummies are perfect for ages 2 and up. Plus, they're vegan, non-GMO, gluten-free, and come in delicious strawberry flavor.

What We Like
Easy and tasty way to supplement vitamin D and B12
Promotes bone health and energy boosts
No hard-to-swallow pills or capsules
Vegan, non-GMO, and gluten-free
60 servings per bottle
#TOP 4

Vitamin B12 Gummies for Energy & Immune Support

NNB12Gummies
Vitamin B12 Gummies for Energy & Immune Support Cover
B12 Gummies, Extra Strength Energy 3000 mcg Vitamin B12, B-12 Energy Metabolism & Immune System Support, Chewable Supplement for Adults & Kids, Caffeine Free, Berry Flavored Gummy, Vegan - 120 Count

Get a natural energy boost with these Vitamin B12 Gummies. The high absorption formula helps convert food into energy, while also offering immune system support at the cellular level. These premium gummies are third-party certified and use only the highest quality cyanocobalamin. Suitable for both adults and kids, these vegan gummies have a delicious raspberry flavor.

What We Like
Provides essential energy by helping to convert food into fuel for the body
High absorption formula for better absorption of Vitamin B12
Offers immune system support at the cellular level for overall wellness

Live Conscious Vegan Vitamin B12 Sublingual Liquid Drops

2 Fl Oz (Pack of 1)
Live Conscious Vegan Vitamin B12 Sublingual Liquid Drops Cover
Vegan Vitamin B12 Sublingual Liquid Drops by Live Conscious- Methylcobalamin Max Strength B12 5000mcg Formula - Vegan B 12 Vitamin Support Energy, Promote Memory & Aid Immune System - 60 Serving

Live Conscious Vegan Vitamin B12 Sublingual Liquid Drops is a fast-absorbing, earth-friendly formula that supports your energy, mood, memory, and immune system. The Methylcobalamin B12 5000 Mcg Vegan Formula helps to convert carbohydrates into glucose, leading to greater cellular energy production. It also promotes the production of white blood cells, which is crucial for immune system support and protection. By using an under the tongue dropper, it ensures fast absorption. Live Conscious Vegan B12 is lactose-free, gluten-free, soy-free, non-GMO, and made in the U.S. from globally sourced ingredients.

What We Like
Promotes greater cellular energy production.
Supports mood and energy levels.
Fast-absorbing, thanks to the under the tongue dropper.
Promotes immune system support and protection.
Earth-friendly, lactose-free, gluten-free, soy-free, non-GMO, and made in the U.S. from globally sourced ingredients.

EZ Melts Dissolvable Vitamin B12 Supplements

8567863
EZ Melts Dissolvable Vitamin B12 Supplements Cover
EZ Melts B12 Sublingual Vitamin 2,500 mcg, Methylcobalamin, Sugar-Free, 3-Month Supply

Try EZ Melts Dissolvable Vitamin B12 Supplements to improve your overall well-being. With a bioactive form of B-12 vitamin, this vegan supplement supports healthy immune function, promotes mental clarity, and aids the body in breaking down food into energy. The cherry flavor taste is created using plant-derived ingredients, and the tablets dissolve in your mouth for easy absorption. Made in the USA with no artificial colors, flavors, or sweeteners and no pesky irritants like gluten or dairy, you can be confident in consistent quality.

What We Like
Supports healthy immune function and promotes mental clarity
Dissolves in your mouth for easy absorption
No artificial colors, flavors, or sweeteners
Made in the USA with no pesky irritants like gluten or dairy

Amazon Basics Vitamin B12 Gummies

Amazon Basics
SMARA-HPC-6215
Amazon Basics Vitamin B12 Gummies Cover
Amazon Basics Vitamin B12 500 mcg Gummies - Normal Energy Production and Metabolism, Immune System Support, Raspberry, 100 Count (2 per Serving) (Previously Solimo)

Amazon Basics B12 Gummies are designed to support your energy production, promote metabolism, enhance brain function, and boost immune health. These vegan gummies help convert food into fuel, support red blood cell formation, improve cognition, and maintain a healthy immune system. With a raspberry flavor and free from gluten, wheat, dairy, soy, and egg, these gummies provide a convenient way to meet your B12 needs. Stay energized and support your overall well-being with Amazon Basics B12 Gummies.

What We Like
Energy production support
Metabolism promotion
Brain function enhancement
#TOP 8

HERBIFY Organic Methylated B12 Supplement

2 Fl Oz (Pack of 1)
HERBIFY Organic Methylated B12 Supplement Cover
HERBIFY Vitamin B12 Organic Methylated Multivitamin Energy Supplements for Women & Men - Liquid B12 Vitamins 5000 Mcg Methylfolate - Energy Support and Natural Immune Health Liquid Vitamin 2 Oz

HERBIFY B12 Energy Booster is designed to enhance your vitality and overall wellness. With its high-potency methylated B complex, this supplement helps you unlock the benefits of vitamin B12, which can improve your energy levels and support metabolism. It's perfect for both men and women looking for a natural way to fight fatigue. Additionally, it offers immune support, ensuring your body stays resilient. The formula also promotes cognitive clarity, helping you focus and stabilize your mood throughout the day. With these advantages, you can feel energized and balanced in your daily life.

What We Like
Boosts energy levels
Supports immune health
Enhances cognitive function
Mood stabilization
#TOP 9

NIUSISE L-Methylfolate 15mg Gummies

NIUSISE
NIUSISE L-Methylfolate 15mg Gummies Cover
NIUSISE L-Methylfolate 15mg Gummies for Adult, Sugar Free Gummies Help Improve Energy, Brain Function - Active Folic Acid & Vitamin B12 Supplement for Immune Support, Non-GMO, Gluten Free

NIUSISE Methylfolate Gummies are designed to support your overall health with their active form of folic acid. These gummies help convert homocysteine to methionine, which can enhance your mood and energy levels, reducing feelings of fatigue. They also promote optimal methylation, contributing to the production of important neurotransmitters like serotonin and dopamine, which can elevate your mental wellness. Plus, their formulation ensures easy absorption, allowing your body to quickly benefit from the nutrients in each delicious gummy, making your supplement routine effortless.

What We Like
Active folic acid for health
Boosts energy and mood
Supports neurotransmitter production
Quick and easy absorption
Non-GMO and gluten-free
#TOP 10

WellYeah B12 Gummies 1000mcg

WYB12RA-30
WellYeah B12 Gummies 1000mcg Cover
WellYeah Vitamin B12 1000mcg Gummies - for Energy, Mood, Metabolism and Immune System Support - Vegan Friendly and Gluten-Free, GMO Free and Doctor Recommended - 60 Gummies

WellYeah B12 Gummies are a delicious way to boost your wellness. These gummies support your immune system and help maintain normal brain function, making them a valuable addition to your daily routine. With extra B12, you can enhance your energy levels by converting food into fuel, which is essential for staying active. The formulation is safe, as it is free from gluten, dairy, and nuts, making it suitable for a wide range of dietary needs. Plus, their tasty berry flavor makes taking vitamins enjoyable, encouraging you to stick to your health goals.

What We Like
Supports energy production
Boosts immune system
Safe for various diets
Tasty berry flavor
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Does vitamin B12 support immune system?

In addition to those numerous functions, vitamin B12 also offers critical immune system support. Cells in a strong immune system thrive on oxygen, which is delivered via red blood cells. Vitamin B12 is integral to red blood cell production, ensuring the immune system gets the oxygen it needs.

2. Which form of vitamin B12 is best?

The vitamin itself is available in several forms, most commonly methylcobalamin and cyanocobalamin. However, the best option is clear. “Go for the methylcobalamin form of vitamin B12 because it is absorbed much better by the body than other forms of vitamin B12,” says Dr. Boyer.

3. Is it good to take vitamin B12 tablets?

When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.

4. Which vitamin B is best for immune system?

Vitamin B6 is in charge of keeping the immune system strong, making new red blood cells, and transporting oxygen throughout the body. Vitamin B has also been shown to improve migraines. Foods rich in pyridoxine are chicken, salmon, tuna, leafy greens, and chickpeas.

Editor's Notes

During our vitamin b12 supplement for immune support research, we found 24 vitamin b12 supplement for immune support products and shortlisted 10 quality products. We collected and analyzed 209,987 customer reviews through our big data system to write the vitamin b12 supplements for immune support list. We found that most customers choose vitamin b12 supplements for immune support with an average price of $14.36.

The vitamin b12 supplements for immune support are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b12 supplements for immune support, including Pure Encapsulations, MaryRuth Organics, Nature's Nutrition, Live Conscious, EZ Melts. The seller of top 1 product has received honest feedback from 54,832 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.