Best Vitamin B12 Supplements for Immune Support of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 20, 2026

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Vitamin B12 supplements are a popular choice for those looking to boost their immune system. This essential vitamin plays a crucial role in the production of red blood cells and DNA, as well as supporting healthy nerve function. While many foods contain B12, such as meat, fish, and dairy, some individuals may struggle to get enough through their diet alone. Vitamin B12 supplements come in various forms, including capsules, tablets, and even gummies, making it easy to incorporate into your daily routine. With regular use, these supplements can help support a healthy immune system, improve energy levels, and promote overall well-being.

At a Glance: Our Top Picks

Amazon Solimo Vitamin B12 Gummies Cover #TOP 1
Amazon Solimo Vitamin B12 Gummies
ftb score rating icon 9.8
Goli Apple Cider Vinegar Gummies Cover #TOP 2
Goli Apple Cider Vinegar Gummies
ftb score rating icon 9.7
EZ Melts Dissolvable Vitamin B12 Supplements Cover #TOP 3
EZ Melts Dissolvable Vitamin B12 Supplements
ftb score rating icon 9.5

Top 4 Vitamin B12 Supplements for Immune Support

Amazon Solimo Vitamin B12 Gummies

Amazon Basics
SMARA-HPC-7238
Amazon Solimo Vitamin B12 Gummies Cover
Amazon Basics Vitamin B12 3000 mcg Gummies, Normal Energy Production and Metabolism, Immune System Support, Raspberry, 100 Count (2 per serving) (Previously Solimo)

The Amazon Solimo Vitamin B12 Gummies support energy production and metabolism and promote healthy immune function, while also aiding in normal brain function and cognition. The raspberry flavored vegan gummies come with 100 gummies per bottle, enough for a one-and-a-half month supply when taken daily at listed serving size. The gummies are gluten-free, and do not contain wheat, dairy, soy, or egg.

What We Like
Pleasant raspberry flavor
High B12 dosage
Vegan and allergen-free
Soft, easy-to-chew texture
Affordable price

Goli Apple Cider Vinegar Gummies

App-01
Goli Apple Cider Vinegar Gummies Cover
Goli Apple Cider Vinegar Gummies - Worlds First ACV Gummy with Vitamin B12, Beetroot & Pomegranate - Vegan, Non-GMO, Gluten-Free - 60 Count (Pack of 1)

Goli ACV Gummies offer a delicious and convenient way to incorporate the benefits of apple cider vinegar into your daily routine. Each gummy is vegan, non-GMO, gluten-free, and gelatin-free, making them suitable for various dietary preferences. Made in the USA with high-quality, locally and globally sourced ingredients, these gummies ensure you receive a reputable product. The patented formula includes essential Vitamin B12, which supports your energy levels, immune function, and overall health. With a unique flavor profile, Goli ACV Gummies make it easy to enjoy the traditional benefits of apple cider vinegar for digestion and gut health.

What We Like
Effective alternative to ACV shots
Supports digestion and energy
Vegan, gluten-free, gelatin-free
Pleasant, fresh taste
Outstanding customer service

EZ Melts Dissolvable Vitamin B12 Supplements

40184
EZ Melts Dissolvable Vitamin B12 Supplements Cover
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 Sublingual Tablets (90 Servings)

Try EZ Melts Dissolvable Vitamin B12 Supplements to improve your overall well-being. With a bioactive form of B-12 vitamin, this vegan supplement supports healthy immune function, promotes mental clarity, and aids the body in breaking down food into energy. The cherry flavor taste is created using plant-derived ingredients, and the tablets dissolve in your mouth for easy absorption. Made in the USA with no artificial colors, flavors, or sweeteners and no pesky irritants like gluten or dairy, you can be confident in consistent quality.

What We Like
Supports healthy immune function and promotes mental clarity
Dissolves in your mouth for easy absorption
No artificial colors, flavors, or sweeteners
Made in the USA with no pesky irritants like gluten or dairy
#TOP 4

NUSAVA Vitamin B12 Liquid Drops

NUS-LIQVITB12-DRPS-2PK
2 Fl Oz (Pack of 2)
NUSAVA Vitamin B12 Liquid Drops Cover
(2 Pack) Vitamin B12 and B6 Liquid Drops, B12 Sublingual Vitamin B Complex - B 12 Vitamin 5000mcg - B12 Methylcobalamin for Energy, Brain, and Heart Support with 27,200 mcg, Raspberry, 80 Servings

NUSAVA B12 Drops provide a potent blend of Vitamin B12, B6, B1, Niacin, and Folic Acid to support your body functions. Experience brain support, energy metabolism, heart wellness, and immune support with each sublingual drop. Enjoy rapid absorption by placing the drops under your tongue for 30 seconds. This organic formula is free from fillers, vegan, non-GMO, and gluten-free. If you seek a 5-in-1 B12 complex, try NUSAVA B12 Drops for ultimate benefits.

What We Like
Easy to take
Quick absorption
Increased energy levels
Long-lasting bottle
Pleasant taste
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Does vitamin B12 support immune system?

In addition to those numerous functions, vitamin B12 also offers critical immune system support. Cells in a strong immune system thrive on oxygen, which is delivered via red blood cells. Vitamin B12 is integral to red blood cell production, ensuring the immune system gets the oxygen it needs.

2. Which form of vitamin B12 is best?

The vitamin itself is available in several forms, most commonly methylcobalamin and cyanocobalamin. However, the best option is clear. “Go for the methylcobalamin form of vitamin B12 because it is absorbed much better by the body than other forms of vitamin B12,” says Dr. Boyer.

3. Is it good to take vitamin B12 tablets?

When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. While the recommended daily amount of vitamin B-12 for adults is 2.4 micrograms, higher doses have been found to be safe. Your body absorbs only as much as it needs, and any excess passes through your urine.

4. Which vitamin B is best for immune system?

Vitamin B6 is in charge of keeping the immune system strong, making new red blood cells, and transporting oxygen throughout the body. Vitamin B has also been shown to improve migraines. Foods rich in pyridoxine are chicken, salmon, tuna, leafy greens, and chickpeas.

Editor's Notes

During our vitamin b12 supplement for immune support research, we found 24 vitamin b12 supplement for immune support products and shortlisted 4 quality products. We collected and analyzed 4,076,644 customer reviews through our big data system to write the vitamin b12 supplements for immune support list. We found that most customers choose vitamin b12 supplements for immune support with an average price of $17.60.

The vitamin b12 supplements for immune support are available for purchase. We have researched hundreds of brands and picked the top brands of vitamin b12 supplements for immune support, including Goli, EZ Melts, NUSAVA. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.