Best Capsules L-Lysine Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 13, 2026

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Capsules L-Lysine Supplements are a popular choice for those looking to boost their immune system and promote healthy skin and tissue. Made with high-quality ingredients, these supplements provide the essential amino acid L-Lysine, which cannot be produced by the body and must be obtained through diet or supplementation. Capsules L-Lysine Supplements are also known for their ability to support respiratory health and aid in the prevention and treatment of cold sores. With easy-to-swallow capsules and no added fillers or preservatives, these supplements are a convenient and effective way to support overall health and wellness.

At a Glance: Our Top Picks

Pure Encapsulations L-Lysine Capsules Cover #TOP 1
Pure Encapsulations L-Lysine Capsules
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Bronson L-Lysine Defense Immune Support Complex Cover #TOP 2
Bronson L-Lysine Defense Immune Support Complex
ftb score rating icon 9.8
Nutricost L-Lysine 1000mg, 500 Capsules Cover #TOP 3
Nutricost L-Lysine 1000mg, 500 Capsules
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Top 10 Capsules L-Lysine Supplements

#TOP 1

Pure Encapsulations L-Lysine Capsules

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Pure Encapsulations L-Lysine - Essential Amino Acid Supplement for Immune Support & Gum, Lip Health* - with L-Lysine HCl - 90 Capsules

Pure Encapsulations L-Lysine Capsules are an amino acid supplement that provides essential nutrients to help maintain healthy immune function and gum health. With natural defense support, L-Lysine maintains healthy arginine production and supports the body's natural immune defenses. What makes this product stand out is its pure quality, using only premium ingredients sourced from trusted suppliers and free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Immune system support
Oral health benefits
Vegan and hypoallergenic
Easy-to-swallow capsules
Good value packaging

Bronson L-Lysine Defense Immune Support Complex

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Bronson L-Lysine Defense Immune Support Complex 1500 MG L-Lysine Plus Olive Leaf, Garlic, Vitamin C and Zinc - Non-GMO, 90 Vegetarian Capsules

Bronson L-Lysine Defense Immune Support Complex is a non-GMO vegetarian capsule containing L-Lysine, Olive Leaf, Garlic, Vitamin C, and Zinc. L-Lysine helps to maintain healthy production of L-Arginine, support immune health, and maintain healthy lips. Olive Leaf and Garlic are natural immune support ingredients, and Vitamin C and Zinc help replenish the body with essential nutrients to maintain a healthy immune system. The product is tested in a cGMP registered facility in New York and has been trusted since 1960.

What We Like
Cold sore prevention
Immune system support
Clearer skin benefits
High-quality ingredients
Easy to swallow

Nutricost L-Lysine 1000mg, 500 Capsules

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Nutricost L-Lysine 1000mg, 500 Capsules Cover
Nutricost L-Lysine 1000mg Per Serving, 250 Servings, 500 Capsules - Gluten Free, Non-GMO, 500mg Per Capsule

Nutricost's L-Lysine supplement contains 500mg of premium L-Lysine per capsule, providing a 1000mg serving. With 250 servings (500 capsules) of this essential amino acid, users can take 1-2 capsules per serving. The supplement is Non-GMO, Gluten-Free and made in a GMP compliant, FDA-registered facility.

What We Like
Pure L-lysine formula
Supports immune health
Easy to swallow capsules
Great value for price
Helps with skin clarity
#TOP 4

Natural Cure Labs L-Lysine + Monolaurin Capsules

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Natural Cure Labs L-Lysine + Monolaurin 600mg 1:1 Ratio, 100 Capsules

The Natural Cure Labs L-Lysine + Monolaurin Capsules offer a 1:1 ratio of 600mg L-Lysine and 600mg Monolaurin per serving. This award-winning supplement is 100% vegan, non-GMO, and gluten-free, with no artificial preservatives, flavors, or colors. With a clean label and pure ingredients, these capsules are designed to support your health and wellness needs. Made in the USA and lab tested, this supplement is GMP Certified to ensure quality and safety.

What We Like
1:1 ratio of L-Lysine and Monolaurin per serving
Award-winning supplement with clean label and pure ingredients
USA formulated, blended, and bottled, GMP Certified, and lab tested for quality and safety
#TOP 5

NOW Supplements L-Lysine 500mg, 100 Veg Capsules

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NOW Foods Supplements, L-Lysine (L-Lysine Monohydrochloride) 500 mg, Amino Acid, 100 Veg Capsules

NOW Supplements L-Lysine is an amino acid that supports collagen synthesis and healthy immune function. It is necessary for the production of all proteins in the body and is required for the maintenance of the structural proteins collagen and elastin. In addition, it may help support proper cardiovascular function. The product is non-GMO, Halal, and Soy Free, and is packaged in the USA by a family owned and operated company since 1968. The manufacturing process is NPA A-rated GMP certified, ensuring quality and potency.

What We Like
Supports collagen synthesis
May help support healthy immune and cardiovascular function
Non-GMO, Halal, and Soy Free

Clear Probiotics Lip and Skin Health

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Lysine Cold Sore Treatment for Lips with Pre-Probiotics & VIT C | 1 Month Supply | Supercharged Lysine Capsules with Rhamnosus & Acidophilus for Cold Sores Relief, Skin + Gut Health & Immune Support

Clear Probiotics Lip and Skin Health is a probiotic supplement that promotes healthy and beautiful lips and skin. Its special formula contains powerful ingredients like lysine and vitamin C that prevent the production of arginine in the body, the common trigger for lip and mouth blisters. This supplement also balances out the bacteria responsible for outbreaks and improves gut health and microbiome. The vegan and non-GMO formula is 3rd party tested for purity, potency, and safety.

What We Like
Promotes healthy and beautiful lips and skin
Prevents the production of arginine in the body
Improves gut health and microbiome
Contains powerful ingredients like lysine and vitamin C
Vegan and non-GMO formula
#TOP 7

Micro Ingredients Pure L-Lysine 2000mg, 300 Capsules

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Pure L-Lysine 2,000mg, 300 Veggie Capsules | Maximum Potency, Easily Absorbed, Free Form | Essential Amino Acid for Collagen, Lip, & Immune Support | Clean Ingredients Without Fillers

The Micro Ingredients L-Lysine Capsules offer a clean and potent way to support your health. This supplement uses pure, filler-free ingredients, making it easier for your body to digest and absorb the essential amino acid L-Lysine. Each serving delivers a strong 2,000mg dose in natural veggie capsules, helping you maintain consistent lysine levels. Since your body can't make lysine on its own, taking this supplement can support your collagen production, boost your immune system, and help keep your lips healthy. It's a convenient choice for anyone looking to add a high-quality lysine supplement to their routine.

What We Like
Pure, filler-free formula
High 2,000mg potency per serving
Supports collagen and immunity
Easy digestion and absorption
Natural veggie capsules

Life Extension L-Lysine 620mg - Essential Amino Acid for Active Lifestyle

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Life Extension L-Lysine 620mg - Essential Amino Acid for Active Lifestyle Cover
Life Extension L-Lysine, 620 mg, Essential Amino Acid for Healthy nitrogen Balance, Calcium Metabolism, Stress Response & More, Gluten-Free, Non-GMO, Vegetarian, 100 Capsules

The Life Extension L-Lysine supplement is a great option for athletes and those following plant-based diets who may need to supplement with lysine. This essential amino acid helps inhibit glycation, encourages a healthy stress response, and maintains lean body mass and healthy store of nitrogen. The product is gluten-free, non-GMO, and sourced using only the finest raw ingredients with the purity and potency your body deserves. It is manufactured in the USA, based on the latest scientific findings with the exact ingredients and dosages used in the studies that inspired them, ensuring maximum bioavailability and efficacy is achieved.

What We Like
Essential amino acid for building blocks of protein
Encourages healthy stress response and nitrogen balance
Inhibits glycation for graceful aging
#TOP 9

Designs for Health L-Lysine HCL Pills

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Designs for Health L-Lysine HCL Pills 1500mg - Amino Acid Lysine Hydrochloride Nutritional Supplement for Adults - Immune + Bone Health Support - Vegan + Non-GMO (120 Capsules)

Designs for Health L-Lysine HCL Pills provide 1500mg of lysine per serving, which is essential for muscle maintenance, tissue & collagen support, and quick absorption. The product offers lysine in free-form, which is immediately available for absorption and can be put to metabolic use more readily than amino acids contained in dietary protein. The supplement is Non-GMO, Gluten-Free, and Vegetarian-friendly, which assures that it maintains a strict, no-compromises approach to quality raw material selection. The physician's choice for top quality professional strength supplements since 1989, over 50,000 doctors agree that Designs for Health is the way to go.

What We Like
Contains 1500mg of lysine per serving
Free-form lysine offers quick absorption and can be put to metabolic use more readily than amino acids contained in dietary protein
Non-GMO, Gluten-Free, and Vegetarian-friendly
#TOP 10

Vimergy L-Lysine Capsules for Immune Support and Healthy Skin (270 Count)

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Vimergy L-Lysine Capsules for Immune Support and Healthy Skin (270 Count) Cover
Vimergy L-Lysine – Promotes Healthy Skin, Hair & Nails* – Supports Healthy Metabolism* – Vegan, Non-GMO & Gluten-Free – 270 Capsules

Get the benefits of L-Lysine, an essential amino acid, with Vimergy's vegetarian capsules. Each capsule contains 500mg of L-Lysine HCl without any gelatin, citric acid, or gluten. L-Lysine is crucial for making collagen and elastin, promoting healthy skin, bone, and tissue. It also supports healthy fat metabolism by synthesizing carnitine. The vegetarian capsules help maintain a healthy immune system. With 270 servings, you can trust the purity of each capsule as it is Non-GMO, Kosher, and Vegan.

What We Like
Effective health benefits
Fast delivery
Easy to swallow
High-quality brand
Inexpensive option
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Frequently Asked Questions (FAQs)

1. What are the benefits of taking L-lysine capsules?

L-lysine capsules offer several benefits. Lysine is an essential amino acid that supports various functions in the body. It can improve blood sugar control, help manage anxiety and stress, promote collagen formation, and aid in wound healing. Since our bodies cannot produce lysine, taking it through food or supplements is necessary.

2. What to avoid when taking lysine?

It is important to inform your healthcare provider about all the medications you are using. Avoid taking lysine without medical advice if you are using calcium supplements or certain gastrointestinal medicines like prucalopride or tegaserod.

3. Is it safe to take 1000mg of L-lysine daily?

The dosage of L-lysine capsules typically ranges between 500mg and 1,000mg per dose. The specific amount and duration depend on factors like body weight and the condition being addressed. While higher doses may be safe, some individuals may experience side effects such as diarrhea and nausea. It is advised to consult with a healthcare professional before starting any new supplement regimen.

4. Does L-lysine come in capsule form?

Yes, L-lysine is available in capsule form. One example is Now Foods L-lysine 500mg, which contains essential amino acids that support healthy connective tissue and calcium absorption.

5. What are the side effects of taking L-lysine daily?

Possible side effects of daily L-lysine supplementation include diarrhea, abdominal pain, chronic kidney (renal) failure, inflammation in the kidney (interstitial nephritis), and increased calcium absorption. It is advisable to consult a healthcare professional before starting a daily lysine regimen.

6. Who should not take lysine?

While lysine in the diet is generally safe, excessive doses may lead to gallstones. There have been reports of renal dysfunction, including Fanconi syndrome and renal failure. It is crucial to consult a doctor before taking supplemental lysine if you have kidney disease, liver disease, or if you are pregnant or breastfeeding.

7. Should I take lysine in the morning or at night?

While there is no specific time requirement, some studies suggest that doses ranging from 100mg to 4g per day can be beneficial. People who use lysine to enhance their fitness workouts may find it more advantageous to take it before sleep or exercise. However, it is best to follow the advice of a healthcare professional.

8. What is the most absorbable form of L-lysine?

Thorne's Lysine is known for using the purest and most absorbable form of this amino acid. It does not contain unnecessary additives or preservatives, ensuring optimal absorption and effectiveness.

Editor's Notes

During our capsules l-lysine supplement research, we found 24 capsules l-lysine supplement products and shortlisted 10 quality products. We collected and analyzed 100,459 customer reviews through our big data system to write the capsules l-lysine supplements list. We found that most customers choose capsules l-lysine supplements with an average price of $14.41.

The capsules l-lysine supplements are available for purchase. We have researched hundreds of brands and picked the top brands of capsules l-lysine supplements, including Pure Encapsulations, Bronson, Nutricost, Natural Cure Labs, NOW Foods. The seller of top 1 product has received honest feedback from 48,091 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.