Best L-Glutamine Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 11, 2026

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

L-Glutamine supplements are a popular choice among athletes and fitness enthusiasts looking to enhance their muscle recovery and immune system. L-Glutamine is an amino acid that plays a crucial role in protein synthesis and energy production. It is also involved in the maintenance of intestinal health and the regulation of the immune system. These supplements come in various forms such as capsules, tablets, and powders, making it easy to incorporate into any diet or workout routine. L-Glutamine supplements are generally safe for most people, but it is always recommended to consult with a healthcare professional before starting any new supplement regimen.

At a Glance: Our Top Picks

Nutricost L-Glutamine Powder Cover #TOP 1
Nutricost L-Glutamine Powder
ftb score rating icon 9.8
Nutricost Glycine Powder 1lb Cover #TOP 2
Nutricost Glycine Powder 1lb
ftb score rating icon 9.7
Double Wood L-Theanine Supplement 200mg Cover #TOP 3
Double Wood L-Theanine Supplement 200mg
ftb score rating icon 9.5

Top 10 L-Glutamine Supplements

#TOP 1

Nutricost L-Glutamine Powder

No Model
White
Nutricost L-Glutamine Powder Cover
Nutricost L-Glutamine Powder (500 Grams) Unflavored - Gluten Free & Non-GMO, 100 Servings

Boost your workouts and recovery with this unflavored L-Glutamine Powder. Each serving contains 5000mg of powder, providing you with 100 servings per bottle. This vegetarian-friendly powder is also non-GMO, gluten-free, and soy-free. Add it to your daily routine to help support your immune system, maintain muscle mass, and aid in post-workout recovery. Manufactured in a GMP compliant, FDA registered facility, you can trust the quality of this L-Glutamine Powder.

What We Like
Pure glutamine, no fillers
Mixes easily, dissolves well
Supports gut health, digestion
Enhances muscle recovery
Unflavored option blends easily
What We Don't Like
Mild taste issue for some
Flavored version contains sucralose
#TOP 2

Nutricost Glycine Powder 1lb

NTC420101
1 Pound (Pack of 1)
Nutricost Glycine Powder 1lb Cover
Nutricost Glycine Powder 1lb - Non-GMO, Gluten Free

The Nutricost Glycine Powder offers a full pound (16 ounces) of pure glycine, giving you plenty of supply to support your health needs. It comes with a handy scoop, making it easy to measure the right amount every time without guesswork. If you follow the suggested use, this container can last you about five months, which means fewer trips to restock. Plus, it’s made without genetically modified ingredients and is gluten-free, so you can feel confident about its quality and safety. The Nutricost Glycine Powder is designed to be a convenient and reliable choice for those seeking a clean supplement.

What We Like
Improved sleep quality
Sweet, pleasant taste
Easy to dissolve
Supports tendon and tissue health
Dependable product quality
What We Don't Like
Price increase recently
#TOP 3

Double Wood L-Theanine Supplement 200mg

Double Wood L-Theanine Supplement 200mg Cover
L-Theanine 200mg Double Strength - Supports Health Sleep Response and Relaxation - 120 Capsules (Third Party Tested, Gluten Free, Vegan) by Double Wood

Double Wood L-Theanine Capsules are a third-party tested and manufactured supplement in the USA. These capsules support relaxation without causing drowsiness, making them perfect for those who need to stay calm while maintaining mental sharpness. With the convenience of being Non-GMO and Gluten Free, Double Wood L-Theanine capsules provide a natural way to promote relaxation. Additionally, they work synergistically with Magnesium L-Threonate and Apigenin for enhanced results. Take this supplement to experience the benefits of relaxation and sleep support in your daily life.

What We Like
Improves focus and clarity
Reduces anxiety and stress
Enhances mood and relaxation
No jitters or energy crash
Natural ingredients
What We Don't Like
Large capsules
Effects may take time
#TOP 4

Nutricost L-Glutamine Powder 1 KG

NTC025201
Multi
Nutricost L-Glutamine Powder 1 KG Cover
Nutricost L-Glutamine Powder 1 KG - Unflavored, Non-GMO, Gluten Free

Nutricost L-Glutamine Powder is a high-quality supplement that provides 1KG of L-Glutamine Powder per bottle, with 200 servings of 5 grams each. This unflavored, non-GMO, and gluten-free powder is third-party tested to ensure its purity and safety. L-Glutamine is an amino acid that plays a crucial role in muscle recovery and immune system function. With Nutricost L-Glutamine Powder, you can support your post-workout recovery, aid in muscle growth, and enhance your overall health. The scoop included in each bottle makes it easy to measure the right amount of powder for your needs. Nutricost L-Glutamine Powder is manufactured in a GMP compliant, FDA registered facility, ensuring that you get a high-quality product every time.

What We Like
Easy to mix
No flavor or odor
Gentle on stomach
Supports muscle recovery
Good value for price
What We Don't Like
Results may vary individually
#TOP 5

Pure Encapsulations L-Glutamine Supplement

Pure Encapsulations L-Glutamine Supplement Cover
Pure Encapsulations L-Glutamine 500 mg - Supplement for Immune and Digestive Support, Gut Health and Lining, Metabolism, and Muscle Support* - with Free-Form L-Glutamine - 90 Capsules

Boost your metabolism, support your immune and digestive system, and promote lean muscle mass with Pure Encapsulations L-Glutamine Supplement. This supplement is packed with l-Glutamine, the most abundant amino acid in the body, which is essential for tissue repair and gastrointestinal tract support. The supplement also nutritionally supports the mucosal lining and healthy functioning of the gastrointestinal tract. Additionally, l-Glutamine helps promote and preserve lean muscle mass. Pure Encapsulations supplements are made with only premium ingredients sourced from trusted suppliers and are free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Improved gut health
Reduces bloating and discomfort
High quality and well-tested
Gentle, calming digestive effect
Supports regular bowel movements
What We Don't Like
Large pill size
Results may take time
#TOP 6

MuscleTech Glutamine Powder for Post-Workout Recovery

MT-MG-030-01
White
MuscleTech Glutamine Powder for Post-Workout Recovery Cover
Muscletech 100% L-Glutamine Powder for Enhanced Muscle Recovery - Pure L Glutamine Muscle Growth Builder & Energy Boosting Nutritional Supplement for Men & Women - Unflavored, 60 Servings

MuscleTech Platinum 100% Glutamine Powder is a post-workout recovery drink that replenishes the glutamine used during training. With 5g of l-glutamine per serving, it helps support increased cell volume, glycogen replenishment, and muscle protein synthesis. This tasteless, odorless powder dissolves instantly in water or any other beverage, making it easy to use with your preferred daily workout supplements. For optimal results, take two scoops per day, one before and one after your workout.

What We Like
Muscle recovery support
Reduces post-workout soreness
Unflavored and easy mixing
Good price and quantity
Gentle on stomach
What We Don't Like
Short scoop length
Unusual texture
#TOP 7

Nutricost L-Glutamine Capsules

ZL00555
Nutricost L-Glutamine Capsules Cover
Nutricost L-Glutamine 800mg, 180 Capsules - Gluten Free, Non-GMO

Boost your daily dietary supplement with Nutricost L-Glutamine Capsules. With 800mg of L-Glutamine per capsule, you can enjoy 180 servings of L-Glutamine powder in each bottle. Non-GMO, gluten-free, and soy-free, this product is perfect for those with dietary restrictions. This L-Glutamine supplement can help you maintain your workout routine, increase your focus, and support your immune system. Plus, it is manufactured in a GMP compliant, FDA registered facility, ensuring the quality and safety of the product.

What We Like
Promotes hair growth
Reduces hair shedding
Supports gut health
Relieves muscle pain
Excellent value for price
What We Don't Like
Difficult bottle seal
Contains added fiber
#TOP 8

Thorne L-Glutamine Powder

SA519
Thorne L-Glutamine Powder Cover
THORNE - L-Glutamine Powder - Glutamine Powder for GI Health and Immune Function* - 17.8 Oz

Thorne L-Glutamine Powder is a dietary supplement that promotes muscle recovery, supports GI and nerve health, healthy immune function, and nutritional support for wound and burn healing. It is made with the purest possible ingredients and free from major allergens like gluten, soy, dairy, shellfish, or fish. Thorne is a trusted brand with science-backed products that have earned the trust of thousands of health-care professionals and families around the world.

What We Like
Improves gut health
Reduces bloating and gas
No taste or odor
Dissolves easily in liquids
Supports muscle recovery
What We Don't Like
High price point
Possible mild constipation
#TOP 9

Optimum Nutrition L-Glutamine Capsules

1087705
White
Optimum Nutrition L-Glutamine Capsules Cover
Optimum Nutrition L-Glutamine Muscle Recovery Capsules, 1000mg, 240 Count (Package May Vary)

Recover faster after intense workouts with Optimum Nutrition L-Glutamine Capsules. This product is packed with 1000 milligrams of pure L-Glutamine per 2 capsules. As the most abundant amino acid in the body, L-Glutamine plays a vital role in muscle protein development. During prolonged periods of intense exercise, L-Glutamine levels may be depleted, making this supplement a must-have for fitness enthusiasts. Plus, the package comes in two sizes - 120 count and 240 count, giving you flexibility in your purchase. Please note that exposure to heat or sunlight may lead to melting/damage of the product. However, Amazon stores and ships products in accordance with the manufacturer's recommendations, ensuring that you receive a high-quality product.

What We Like
Muscle recovery support
No taste or aftertaste
Easy to mix or swallow
Improved gut health
Trusted brand quality
What We Don't Like
Occasional capsule clumping
#TOP 10

NOW L-Glutamine Capsules

733739000927
White
NOW L-Glutamine Capsules Cover
NOW Foods Supplements, L-Glutamine 500 mg, Nitrogen Transporter*, Amino Acid, 120 Veg Capsules

Boost your immune function with these amino acid supplements from NOW. Glutamine is a conditionally essential amino acid that your body may require more of than it can produce, especially during recovery. These capsules help maintain healthy nitrogen balance and act as a major nitrogen transporter in your body. Additionally, they are Halal, non-gmo, kosher, dairy-free, egg-free, made without gluten, nut-free, soy-free, vegan, and vegetarian. The NPA A-rated GMP certification ensures that the manufacturing process has been examined in every aspect, including laboratory/testing methods for stability, potency, and product formulation. These capsules are packaged in the USA by a family-owned and operated company since 1968. Please note that exposure to heat or sunlight may lead to melting/damage of the product, so customers are expected to be available during the delivery. During summer months, products may arrive warm, but Amazon stores and ships products in accordance with manufacturers' recommendations.

What We Like
Gut health support
Muscle recovery improvement
Reduces cramps
Easy to swallow
Vegan formula
What We Don't Like
May cause mild gas
No effect for some users
Buying Guide Image

Best Choices of L-Glutamine Supplements for You

Introduction

L-glutamine is an amino acid that is naturally present in the human body. It is involved in many important bodily functions, including the metabolism of proteins and the maintenance of the immune system. As such, it is often considered a crucial nutrient for maintaining good health.

Why Consider L-Glutamine Supplements?

While the body can produce its own L-glutamine, certain situations can cause the body's natural production to fall short. This can include intense exercise, illness, or injury. In these cases, L-glutamine supplements may be necessary to ensure that the body has sufficient levels of this important amino acid.

Choosing the Right Supplement

With so many L-glutamine supplements on the market, it can be overwhelming to try to choose the right one. Here are a few key things to consider when selecting an L-glutamine supplement:

  • Quality: As with any supplement, it's important to choose a high-quality product. Look for supplements that are manufactured in a facility that follows good manufacturing practices (GMP), and be sure to read the label carefully to understand what you're getting.

  • Dosage: The recommended daily dosage of L-glutamine varies depending on the individual and their specific needs. Some people may need as little as 500 mg per day, while others may require up to 5,000 mg per day. Be sure to consult with a healthcare provider to determine the right dosage for you.

  • Form: L-glutamine supplements are available in a variety of forms, including capsules, tablets, powders, and liquids. Choose the form that is most convenient for you and that you are most likely to take consistently.

  • Purpose: L-glutamine has a range of potential benefits, including improving gut health, boosting the immune system, and aiding in muscle recovery. Consider what you hope to achieve by taking an L-glutamine supplement, and choose a product that is specifically designed to support that goal.

Conclusion

L-glutamine is an important amino acid that plays a crucial role in many bodily functions. If your body's natural production of L-glutamine falls short, an L-glutamine supplement may be necessary to maintain good health. When choosing an L-glutamine supplement, consider factors such as quality, dosage, form, and purpose to ensure that you are getting the right product for your needs.

Frequently Asked Questions (FAQs)

1. What does L-glutamine supplement do?

L-glutamine supplements have been shown to strengthen the immune system and reduce infections, especially those associated with surgery. They may also help prevent or treat multiple organ dysfunction in people in intensive care units after shock or other injuries.

2. Is it safe to take L-glutamine every day?

Taking L-glutamine by mouth is generally safe when used in doses up to 40 grams daily. Mild side effects such as bloating, nausea, dizziness, heartburn, and stomach pain may occur. However, it is important to consult with a healthcare professional before starting any new supplement regimen, especially during pregnancy or breastfeeding.

3. Does L-glutamine reduce belly fat?

Limited research suggests that glutamine supplements may contribute to increased weight loss. A 6-week study on individuals with type 2 diabetes found that taking 30 grams of glutamine powder daily improved various risk factors for heart disease and reduced both belly and body fat.

4. When should you take L-glutamine?

It is recommended to take L-glutamine about 10-15 minutes before a meal, on an empty stomach. Ideally, it should be taken 2-3 times per day, before meals. However, it's important to prioritize consistency in taking the supplement rather than the exact timing.

5. Are there any side effects to taking L-glutamine?

Potential side effects of L-glutamine include liver damage, nausea, and headaches. It's important to monitor your body's response and consult with a healthcare professional if you experience any adverse effects.

6. How long does it take to see the benefits of L-glutamine?

The benefits of L-glutamine may take some time to manifest as the substance is stored in the muscles and used gradually. Consistency is key, and it is recommended to take L-glutamine supplements for at least 3 months to allow the body to adjust and experience the desired benefits.

7. What are the pros and cons of L-glutamine?

L-glutamine has several benefits, such as supporting immune function and aiding in the recovery of long-distance athletes. However, excessive use may suppress immune function and negatively impact resistance training, leading to overtraining syndrome. It's important to use L-glutamine supplements responsibly and in consultation with a healthcare professional.

8. Does glutamine get rid of bloating?

If your body lacks the L-glutamine it normally produces, you may experience bloating. In such cases, taking glutamine supplements can help replenish your supply and alleviate bloating.

9. How long does it take L-glutamine to heal the gut?

Research suggests that L-glutamine may start showing benefits for gut health within a few days to a few weeks of starting supplementation. For example, a study found that taking L-glutamine for just three days helped improve gut permeability in athletes after intense exercise.

Editor's Notes

During our l-glutamine supplement research, we found 24 l-glutamine supplement products and shortlisted 10 quality products. We collected and analyzed 243,893 customer reviews through our big data system to write the l-glutamine supplements list. We found that most customers choose l-glutamine supplements with an average price of $21.91.

The l-glutamine supplements are available for purchase. We have researched hundreds of brands and picked the top brands of l-glutamine supplements, including Nutricost, Double Wood Supplements, Pure Encapsulations, MuscleTech, THORNE. The seller of top 1 product has received honest feedback from 33,154 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

L-Glutamine Supplements Comparison Table

#TOP1
#TOP2
#TOP3
#TOP4
#TOP5
#TOP6
#TOP7
#TOP8
#TOP9
#TOP10
Brand Nutricost Nutricost Double Wood Supplements Nutricost Pure Encapsulations MuscleTech Nutricost THORNE Optimum Nutrition NOW Foods
Flavor Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored Unflavored No Flavour
Unit Count 17.6 Ounce 16.0 Ounce 120 Count 1000.0 Ounce 90 Count 10.58 Ounce 180 Count 17.8 Ounce 120 Count 120 Count
Item Form Powder Powder Capsule Powder Capsule Powder Capsule Powder Capsule Capsule
Item Weight 20.5 Ounces 1 Pounds 80 Grams 40.3 Ounces 500 Milligrams 0.82 Pounds 7 Ounces 17.8 Ounces 0.15 Kilograms 3.2 Ounces
Item dimensions L x W x H 4.49 x 4.09 x 5.31 inches 3.7 x 3.7 x 4.7 inches 1.5 x 2 x 3.13 inches 5 x 5 x 7.2 inches 3.1 x 1.8 x 1.1 inches 3.68 x 3.68 x 5.78 inches - 4.74 x 4.74 x 5 inches 6 x 5 x 4 inches 2 x 2 x 4 inches
Product Benefits Digestive Health Support, Immune Support, Weight Management, Brain Health Support - Sleep Support Brain Health Support Gut Health,Muscle Therapy Replenishing Nutritional Supplement Nutritional Support Muscle Growth Immune Support
Primary Supplement Type L-Glutamine - Magnesium L-Glutamine - Creatine Non-specific L-Glutamine L-Glutamine multivitamin
Diet Type Vegetarian Gluten Free Gluten Free Vegetarian - Gluten Free Gluten Free - Gluten Free Halal, Kosher, Vegan
Special Ingredients L-Glutamine Glycine Theanine L-Glutamine - - L-Glutamine - L-Glutamine Amino Acid, L-Glutamine
Age Range (Description) - Adult - - Adult Adult Adult Adult - -
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.4
ftb score rating icon 9.3
ftb score rating icon 9.3
ftb score rating icon 9.1
ftb score rating icon 9.0
ftb score rating icon 9.0
ftb score rating icon 8.9
Where to Buy