Best L-Glutamine Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2025

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L-Glutamine supplements are a popular choice among athletes and fitness enthusiasts looking to enhance their muscle recovery and immune system. L-Glutamine is an amino acid that plays a crucial role in protein synthesis and energy production. It is also involved in the maintenance of intestinal health and the regulation of the immune system. These supplements come in various forms such as capsules, tablets, and powders, making it easy to incorporate into any diet or workout routine. L-Glutamine supplements are generally safe for most people, but it is always recommended to consult with a healthcare professional before starting any new supplement regimen.

At a Glance: Our Top Picks

NOW L-Glutamine Capsules Cover #TOP 1
NOW L-Glutamine Capsules
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Pure Encapsulations L-Glutamine Supplement Cover #TOP 2
Pure Encapsulations L-Glutamine Supplement
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Nutricost L-Glutamine Powder Cover #TOP 3
Nutricost L-Glutamine Powder
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Top 10 L-Glutamine Supplements

#TOP 1

NOW L-Glutamine Capsules

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NOW Foods Supplements, L-Glutamine 500 mg, Nitrogen Transporter*, Amino Acid, 120 Veg Capsules

Boost your immune function with these amino acid supplements from NOW. Glutamine is a conditionally essential amino acid that your body may require more of than it can produce, especially during recovery. These capsules help maintain healthy nitrogen balance and act as a major nitrogen transporter in your body. Additionally, they are Halal, non-gmo, kosher, dairy-free, egg-free, made without gluten, nut-free, soy-free, vegan, and vegetarian. The NPA A-rated GMP certification ensures that the manufacturing process has been examined in every aspect, including laboratory/testing methods for stability, potency, and product formulation. These capsules are packaged in the USA by a family-owned and operated company since 1968. Please note that exposure to heat or sunlight may lead to melting/damage of the product, so customers are expected to be available during the delivery. During summer months, products may arrive warm, but Amazon stores and ships products in accordance with manufacturers' recommendations.

What We Like
Effective appetite suppressant
Improved digestion and reflux management
Good value for money
Supports weight management
What We Don't Like
Results may vary
Requires multiple pills for some
#TOP 2

Pure Encapsulations L-Glutamine Supplement

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Pure Encapsulations L-Glutamine 500 mg - Supplement for Immune and Digestive Support, Gut Health and Lining, Metabolism, and Muscle Support* - with Free-Form L-Glutamine - 90 Capsules

Boost your metabolism, support your immune and digestive system, and promote lean muscle mass with Pure Encapsulations L-Glutamine Supplement. This supplement is packed with l-Glutamine, the most abundant amino acid in the body, which is essential for tissue repair and gastrointestinal tract support. The supplement also nutritionally supports the mucosal lining and healthy functioning of the gastrointestinal tract. Additionally, l-Glutamine helps promote and preserve lean muscle mass. Pure Encapsulations supplements are made with only premium ingredients sourced from trusted suppliers and are free from wheat, eggs, tree nuts & peanuts, gluten, artificial colors, flavors & sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers & preservatives.

What We Like
Effective for digestive health
Gentle on the stomach
Helps muscle recovery
Easy to swallow
Reduces muscle soreness
What We Don't Like
Contains corn allergens
A bit pricey
#TOP 3

Nutricost L-Glutamine Powder

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Nutricost L-Glutamine Powder (500 Grams) Unflavored - Gluten Free & Non-GMO, 100 Servings

Boost your workouts and recovery with this unflavored L-Glutamine Powder. Each serving contains 5000mg of powder, providing you with 100 servings per bottle. This vegetarian-friendly powder is also non-GMO, gluten-free, and soy-free. Add it to your daily routine to help support your immune system, maintain muscle mass, and aid in post-workout recovery. Manufactured in a GMP compliant, FDA registered facility, you can trust the quality of this L-Glutamine Powder.

What We Like
High-quality and pure formula
Supports muscle recovery
Promotes gut health
Versatile and easy to mix
Generous serving size
What We Don't Like
Hard to dissolve in liquids
Some users find taste unappealing
#TOP 4

Nutricost L-Glutamine Capsules

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Nutricost L-Glutamine 800mg, 180 Capsules - Gluten Free, Non-GMO

Boost your daily dietary supplement with Nutricost L-Glutamine Capsules. With 800mg of L-Glutamine per capsule, you can enjoy 180 servings of L-Glutamine powder in each bottle. Non-GMO, gluten-free, and soy-free, this product is perfect for those with dietary restrictions. This L-Glutamine supplement can help you maintain your workout routine, increase your focus, and support your immune system. Plus, it is manufactured in a GMP compliant, FDA registered facility, ensuring the quality and safety of the product.

What We Like
Reduces hair loss significantly
Improves hair thickness
Supports gut health
Enhances mood and reduces hunger
Easy to swallow
What We Don't Like
Results may vary for some
Not significant difference noted by everyone
#TOP 5

Thorne L-Glutamine Supplement

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Thorne L-Glutamine Supplement Cover
THORNE L-Glutamine - Amino Acid Supplement for GI Health and Immune Function - 90 Capsules

Recover faster after exercise and maintain your gastrointestinal and immune system health with Thorne L-Glutamine supplement. This amino acid supplement helps repair muscle cells and improves gut permeability and barrier function. It also restores plasma glutamine levels depleted after physical stress and supports wound healing. Thorne Research, the brand behind this supplement, is trusted by over 100 professional teams and is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of the U.S. Olympic Teams.

What We Like
Improved digestion
Increased energy levels
Supports gut health
Easy to incorporate
Effective for digestive symptoms
What We Don't Like
Possible heart palpitations
May affect medication absorption
#TOP 6

Double Wood L Glutamine Capsules

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L Glutamine Capsules - No Fillers (1000mg Servings, 120 Capsules) Non-GMO, Gluten Free, Keto Safe, Vegan Friendly, Third Party Tested (for Endurance and Gut Health) by Double Wood

Double Wood Glutamine Capsules, a vegan and keto-friendly supplement, are designed to support gut health and exercise endurance. The L Glutamine powder may aid in leaky gut repair, reduce bloating and gas, and provide support to the intestinal wall. It can also help boost exercise endurance. With no fillers, these capsules are manufactured in the USA, non-GMO, and gluten-free, ensuring high quality. Each bottle offers a two-month supply, containing 120 capsules of 500mg. If you're looking for a convenient way to promote gut health and exercise endurance, Double Wood Glutamine Capsules could be the right choice for you.

What We Like
Effective for sugar cravings
Inexpensive
High quality
No aftertaste
Easy to take
What We Don't Like
Lack of information
Amazon review issues
#TOP 7

Optimum Nutrition L-Glutamine Capsules

Optimum Nutrition L-Glutamine Capsules Cover
Optimum Nutrition L-Glutamine Muscle Recovery Capsules, 1000mg, 240 Count (Package May Vary)

Recover faster after intense workouts with Optimum Nutrition L-Glutamine Capsules. This product is packed with 1000 milligrams of pure L-Glutamine per 2 capsules. As the most abundant amino acid in the body, L-Glutamine plays a vital role in muscle protein development. During prolonged periods of intense exercise, L-Glutamine levels may be depleted, making this supplement a must-have for fitness enthusiasts. Plus, the package comes in two sizes - 120 count and 240 count, giving you flexibility in your purchase. Please note that exposure to heat or sunlight may lead to melting/damage of the product. However, Amazon stores and ships products in accordance with the manufacturer's recommendations, ensuring that you receive a high-quality product.

What We Like
Effective for muscle recovery
Reduces muscle soreness
High-quality brand reputation
Easy to swallow capsules
Affordable price point
What We Don't Like
Occasional packaging issues
#TOP 8

Life Extension L-Glutamine Supplement

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Life Extension L-Glutamine, 500 mg L-glutamine, amino acid, supports muscle health and immune health, gluten-free, non-GMO, 100 vegetarian capsules

Get the most out of your active lifestyle with Life Extension L-Glutamine Supplement. This amino acid is essential for protein production and is perfect for athletes and those who lead an active lifestyle. It supports gut and immune health, promoting a healthy digestive tract and immune response. Its antioxidant properties help maintain muscle health, especially during heavy exercise. Made with non-GMO and gluten-free ingredients, this supplement is sourced with purity and potency in mind, ensuring maximum bioavailability and efficacy. Live your healthiest life with Life Extension L-Glutamine Supplement.

What We Like
Daily use
Good product presentation
Doctor-recommended
Helps with digestion
Part of routine
What We Don't Like
No noticeable effects
Uncertain benefits
#TOP 9

Pure Encapsulations L-Glutamine Powder | 8 Ounces

Pure Encapsulations L-Glutamine Powder | 8 Ounces Cover
Pure Encapsulations L-Glutamine Powder - Supplement for Immune and Digestive Support, Gut Health and Lining, Metabolism, and Muscle Support* - with Pure Free-Form L-Glutamine - 8 Ounces

With Pure Encapsulations L-Glutamine Powder, you can strengthen your immune and digestive systems, boost your metabolism, promote lean muscle mass, and help support the gastrointestinal tract. This powder is made with only premium ingredients and is free from wheat, eggs, tree nuts and peanuts, gluten, artificial colors, flavors and sweeteners, coatings and shellacs, GMOs, and unnecessary binders, fillers and preservatives.

What We Like
Tasteless and odorless
Dissolves instantly in liquid
Improves GI tract health
Enhances athletic performance
Positive effects on IBS symptoms
What We Don't Like
Relatively high cost
#TOP 10

BulkSupplements L-Glutamine 5000mg Capsules

BulkSupplements L-Glutamine 5000mg Capsules Cover
BulkSupplements.com L-Glutamine Capsules - Glutamine Supplement, L-Glutamine 5000mg - Amino Acid for Gut Health, Gluten Free, 6 Capsules per Serving, 360 Capsules (Pack of 1)

BulkSupplements L-Glutamine is designed to enhance your fitness journey with a powerful 5000mg dose per serving. Whether you're an athlete or just someone who enjoys staying active, these capsules can easily fit into your routine and meet various dietary needs. Each serving consists of 6 capsules, making it simple for you to manage your intake according to your personal goals. Furthermore, this supplement is backed by third-party testing, ensuring that you receive a product that is both transparent and reliable in quality. You can feel confident in your choice with its commitment to excellence.

What We Like
Effective for muscle recovery
Improves workout performance
Easy to mix in drinks
Helps with digestive issues
Quality supplement
What We Don't Like
Less cost-efficient than powder
High number of capsules needed
Buying Guide Image

Best Choices of L-Glutamine Supplements for You

Introduction

L-glutamine is an amino acid that is naturally present in the human body. It is involved in many important bodily functions, including the metabolism of proteins and the maintenance of the immune system. As such, it is often considered a crucial nutrient for maintaining good health.

Why Consider L-Glutamine Supplements?

While the body can produce its own L-glutamine, certain situations can cause the body's natural production to fall short. This can include intense exercise, illness, or injury. In these cases, L-glutamine supplements may be necessary to ensure that the body has sufficient levels of this important amino acid.

Choosing the Right Supplement

With so many L-glutamine supplements on the market, it can be overwhelming to try to choose the right one. Here are a few key things to consider when selecting an L-glutamine supplement:

  • Quality: As with any supplement, it's important to choose a high-quality product. Look for supplements that are manufactured in a facility that follows good manufacturing practices (GMP), and be sure to read the label carefully to understand what you're getting.

  • Dosage: The recommended daily dosage of L-glutamine varies depending on the individual and their specific needs. Some people may need as little as 500 mg per day, while others may require up to 5,000 mg per day. Be sure to consult with a healthcare provider to determine the right dosage for you.

  • Form: L-glutamine supplements are available in a variety of forms, including capsules, tablets, powders, and liquids. Choose the form that is most convenient for you and that you are most likely to take consistently.

  • Purpose: L-glutamine has a range of potential benefits, including improving gut health, boosting the immune system, and aiding in muscle recovery. Consider what you hope to achieve by taking an L-glutamine supplement, and choose a product that is specifically designed to support that goal.

Conclusion

L-glutamine is an important amino acid that plays a crucial role in many bodily functions. If your body's natural production of L-glutamine falls short, an L-glutamine supplement may be necessary to maintain good health. When choosing an L-glutamine supplement, consider factors such as quality, dosage, form, and purpose to ensure that you are getting the right product for your needs.

Frequently Asked Questions (FAQs)

1. What does L-glutamine supplement do?

L-glutamine supplements have been shown to strengthen the immune system and reduce infections, especially those associated with surgery. They may also help prevent or treat multiple organ dysfunction in people in intensive care units after shock or other injuries.

2. Is it safe to take L-glutamine every day?

Taking L-glutamine by mouth is generally safe when used in doses up to 40 grams daily. Mild side effects such as bloating, nausea, dizziness, heartburn, and stomach pain may occur. However, it is important to consult with a healthcare professional before starting any new supplement regimen, especially during pregnancy or breastfeeding.

3. Does L-glutamine reduce belly fat?

Limited research suggests that glutamine supplements may contribute to increased weight loss. A 6-week study on individuals with type 2 diabetes found that taking 30 grams of glutamine powder daily improved various risk factors for heart disease and reduced both belly and body fat.

4. When should you take L-glutamine?

It is recommended to take L-glutamine about 10-15 minutes before a meal, on an empty stomach. Ideally, it should be taken 2-3 times per day, before meals. However, it's important to prioritize consistency in taking the supplement rather than the exact timing.

5. Are there any side effects to taking L-glutamine?

Potential side effects of L-glutamine include liver damage, nausea, and headaches. It's important to monitor your body's response and consult with a healthcare professional if you experience any adverse effects.

6. How long does it take to see the benefits of L-glutamine?

The benefits of L-glutamine may take some time to manifest as the substance is stored in the muscles and used gradually. Consistency is key, and it is recommended to take L-glutamine supplements for at least 3 months to allow the body to adjust and experience the desired benefits.

7. What are the pros and cons of L-glutamine?

L-glutamine has several benefits, such as supporting immune function and aiding in the recovery of long-distance athletes. However, excessive use may suppress immune function and negatively impact resistance training, leading to overtraining syndrome. It's important to use L-glutamine supplements responsibly and in consultation with a healthcare professional.

8. Does glutamine get rid of bloating?

If your body lacks the L-glutamine it normally produces, you may experience bloating. In such cases, taking glutamine supplements can help replenish your supply and alleviate bloating.

9. How long does it take L-glutamine to heal the gut?

Research suggests that L-glutamine may start showing benefits for gut health within a few days to a few weeks of starting supplementation. For example, a study found that taking L-glutamine for just three days helped improve gut permeability in athletes after intense exercise.

Editor's Notes

During our l-glutamine supplement research, we found 24 l-glutamine supplement products and shortlisted 10 quality products. We collected and analyzed 199,451 customer reviews through our big data system to write the l-glutamine supplements list. We found that most customers choose l-glutamine supplements with an average price of $21.35.

The l-glutamine supplements are available for purchase. We have researched hundreds of brands and picked the top brands of l-glutamine supplements, including NOW Foods, Pure Encapsulations, Nutricost, THORNE, Double Wood Supplements. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

L-Glutamine Supplements Comparison Table

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Brand NOW Foods Pure Encapsulations Nutricost Nutricost THORNE Double Wood Supplements Optimum Nutrition Life Extension Pure Encapsulations BulkSupplements
Unit Count 120 Count 90.0 Count 17.6 Ounce 180 Count 90.0 Count 120.00 Count 240 Count 100 Count 8.0 Ounce 360.0 Count
Item Form Capsule Capsule Powder Capsule Capsule Capsule Capsule Capsule Powder Capsule
Flavor No Flavour Unflavored Unflavored Unflavored Unflavored - Unflavored Unflavored Unflavored Unflavored
Item Weight 0.12 Kilograms 500 Milligrams 500 Grams 7 Ounces 500 Milligrams 0.04 Ounces 0.15 Kilograms 500 Milligrams 8 Ounces -
Item dimensions L x W x H 2.5 x 2.5 x 4.44 inches 3.1 x 1.8 x 1.1 inches 4.33 x 4.33 x 5.51 inches - 2.09 x 2.09 x 3.72 inches 2.3 x 2.3 x 4.2 inches 6 x 5 x 4 inches 2 x 2 x 3.75 inches 3.78 x 3.7 x 3.62 inches 3 x 3 x 4 inches
Product Benefits Immune Support Gut Health,Muscle Therapy Digestive Health Support, Immune Support, Weight Management, Brain Health Support - Amino Acids Gut Health - Muscle Growth Supports healthy muscle mass, Helps maintain energy levels under heavy stress, Helps maintain optimal immune function & gut health Gut Health,Muscle Therapy Immune Support
Age Range (Description) - Adult Adult Adult Adult Adult Adult - Adult Adult
Special Ingredients Amino Acid, L-Glutamine - L-Glutamine L-Glutamine - - Amino Acid, L-Glutamine L-Glutamine (free form amino acid) - -
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.3
ftb score rating icon 9.1
ftb score rating icon 8.9
ftb score rating icon 8.9
ftb score rating icon 8.8
ftb score rating icon 8.6
ftb score rating icon 8.5
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