Best Essential Fatty Acid Combination Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 16, 2025

* We independently evaluate all recommended products and services. If you click on links we provide, we may receive compensation.

Essential Fatty Acid Combination Supplements are a popular choice for those looking to improve their overall health and wellness. These supplements contain a blend of omega-3 and omega-6 fatty acids, which are essential for maintaining healthy brain function, cardiovascular health, and joint mobility. They are often touted for their ability to reduce inflammation, improve skin health, and support a healthy immune system. Many people choose to take these supplements daily, either in capsule or liquid form, to ensure they are getting the right balance of essential fatty acids. With so many benefits, it's no wonder that Essential Fatty Acid Combination Supplements are becoming a staple in many people's daily health routines.

At a Glance: Our Top Picks

Animal Omega-Omega 3 6 Supplement Cover #TOP 1
Animal Omega-Omega 3 6 Supplement
ftb score rating icon 9.8
NOW Supplements Pumpkin Seed Oil Softgels Cover #TOP 2
NOW Supplements Pumpkin Seed Oil Softgels
ftb score rating icon 9.7
Pure Encapsulations EPA/DHA Essentials Cover #TOP 3
Pure Encapsulations EPA/DHA Essentials
ftb score rating icon 9.5

Top 10 Essential Fatty Acid Combination Supplements

#TOP 1

Animal Omega-Omega 3 6 Supplement

FID129
Animal Omega-Omega 3 6 Supplement Cover
Animal Advanced Omega Essential Fatty Acids - High Potency 3500mg Omega 3 & Omega 6 Supplement with EPA, DHA, ALA, CLA, GLA for Heart, Brain, Joint, Skin, Eye, Metabolism, Immune Health - 30 Day Pack

Animal Omega is an essential fatty acid combination supplement that provides 10 different sources of omega 3 and omega 6 paired with an absorption complex to maximize each daily pack. It helps reduce inflammation, keep your heart healthy, and produce testosterone. With individually packed servings, you can take it on the go, anywhere, and it absorbs best with foods. Note that exposure to heat or sunlight may lead to melting/damage of the product.

What We Like
Effective for cholesterol management
Improves joint health
Convenient dosage packs
Enhances skin, hair, and nails
Easy to swallow capsules
What We Don't Like
Individual packs need tear strip
#TOP 2

NOW Supplements Pumpkin Seed Oil Softgels

1843
Green/Yellow
NOW Supplements Pumpkin Seed Oil Softgels Cover
NOW Foods Supplements, Pumpkin Seed Oil 1000 mg with Essential Fatty Acids and Phytosterols, Cold Pressed, 200 Softgels

NOW Supplements Pumpkin Seed Oil Softgels are a great way to get essential fatty acids and phytosterols. This nutritional oil is cold-pressed from the highest quality Non-GMO pumpkin seeds, ensuring that you get the best possible product. These softgels are also free from common allergens like eggs, making them suitable for people with allergies. With 200 softgels per bottle, this product provides a convenient way to add pumpkin seed oil to your daily routine.

What We Like
Easy to swallow softgels
Supports hair growth
Improves bladder health
No unpleasant aftertaste
Good value for money
What We Don't Like
Large capsule size
Initial digestive adjustment period

Pure Encapsulations EPA/DHA Essentials

Pure Encapsulations EPA/DHA Essentials Cover
Pure Encapsulations EPA/DHA Essentials - Fish Oil Concentrate Supplement to Support Cardiovascular Health - Premium EPA & DHA Supplement with Omega 3-90 Softgel Capsules

Pure EPA/DHA Essentials is an ultra-pure fish oil concentrate supplement that supports cardiovascular health, joints and tissue health. It contains EPA and DHA which are essential for heart health by promoting healthy triglyceride and lipid metabolism, maintaining optimal blood flow, and supporting platelet function. Additionally, the omega-3 acids in this supplement are crucial for cognitive function as they are important components of neuronal cell membranes. Pure EPA/DHA Essentials is made with premium ingredients, ensuring its potency and purity. It is also free from common allergens and unnecessary additives, making it a trustworthy choice for those seeking a high-quality fish oil supplement.

What We Like
Effective for joint pain relief
Quality ingredients, no additives
Supports cardiovascular and brain health
Recommended by healthcare professionals
Easy to swallow capsules
What We Don't Like
Some may find fishy aftertaste
#TOP 4

Swanson Pumpkin Seed Oil Softgel Capsules

SO15
Swanson Pumpkin Seed Oil Softgel Capsules Cover
Swanson Pumpkin Seed Oil Brain Health Cardiovascular Support High Bioavailable Essential Fatty Acids (EFAs) Combination Herbal Supplement 1000 mg 100 Softgel Capsules

Swanson Pumpkin Seed Oil Softgel Capsules are a natural way to support men's health with a powerful formula. The highly bioavailable formula promotes easy absorption to support overall wellness, including cardiovascular support and brain health. For best results, take one pumpkin seed oil softgel capsule per day with food and water. Swanson's commitment to quality includes nearly 50 years of delivering health products worldwide, made in GMP certified facilities, and purity and potency testing includes independent third-party labs. Plus, there's a money-back guarantee.

What We Like
Reduces bathroom trips
Helps with stomach issues
Positive effects on skin
Natural ingredients
Cost-effective alternative
What We Don't Like
May not fully resolve issues
Possible initial discomfort
#TOP 5

NOW Wheat Germ Oil

P27753
NOW Wheat Germ Oil Cover
NOW Foods Supplements, Wheat Germ Oil with Essential Fatty Acids (EFAs), Nutritional Oil, 16-Ounce

NOW Wheat Germ Oil is a nutritional oil that offers a variety of benefits. It is not bleached, deodorized, or hydrogenated, ensuring its original quality. Packed with essential fatty acids, each tablespoon of this oil contains naturally occurring vitamin E and octacosanol, with over 1000 mcg of octacosanol per serving. These nutrients are known for their numerous health benefits, including supporting heart health, promoting healthy skin and hair, and boosting immune function. NOW Wheat Germ Oil is also classified as Halal, Kosher (Triangle K), and Non-GMO Project Verified, guaranteeing its quality and purity. With a long-standing history since 1968, this family-owned and operated product is manufactured in the USA. Experience the convenience and reliability of NOW Wheat Germ Oil, a trusted supplement for your essential fatty acid needs.

What We Like
Improves skin tone and firmness
Great for moisturizing dry skin
High levels of natural vitamin E
Effective for stretch marks
Positive effects on hair health
What We Don't Like
Unpleasant smell
May feel greasy on skin
#TOP 6

YES ULTIMATE EFAs Omega 3 6 Parent High EFAs, Plant Based, Cold Pressed, Burpless, Keto, 120 Soft Gels

Capsules
YES ULTIMATE EFAs Omega 3 6 Parent High EFAs, Plant Based, Cold Pressed, Burpless, Keto, 120 Soft Gels Cover
ULTIMATE EFAs Omega 3 6 Parent EFA Fish Oil Alternative, Organic Plant Based, Vegetarian, Burpless, No Fishy Aftertaste (120 Soft Gels) by YES Your Essential Supplements. Made in USA.

If you're looking for a way to replenish your body's precious Parent Essential Oils, YES Ultimate EFAs Supplements are the ideal solution. These supplements are produced with cold-pressed organic seed oils containing Parent Omega-6 and Parent Omega-3. Your body cannot make Parent Essential Oils and they are “essential” to all of the cells in your body. The only way to get these oils is through your diet, and if you eat processed foods then many of the EFAs you are getting have already been irreparably altered by food processors. With Parent Omega-6 from sunflower and evening primrose and Parent Omega-3 from flax and hemp, this supplement is a great alternative to fish oil, providing heart health, eczema support and an immunity boost.

What We Like
Improves energy levels
Supports skin and hair health
Vegetarian-friendly formulation
High-quality, effective ingredients
Benefits for pets
What We Don't Like
Pricey, but worth it
#TOP 7

Youngevity Ultimate EFA Plus Soft Gels

Youngevity Ultimate EFA Plus Soft Gels Cover
Youngevity Ultimate EFA Plus – Essential Fatty Acids, 90 Soft Gels – Balanced Fish Oil Formula for Heart, Brain, Joint, Skin Health – Omega-3, Omega-6, Omega-9 Supplement for Optimal Health Support

Youngevity EFA Plus is designed to support your heart and brain health with its high-quality fish oil blend. This supplement combines Omega-3, Omega-6, and Omega-9 fatty acids into one convenient soft gel, making it easy for you to boost your overall wellness. By taking just one capsule daily, you can enhance your cognitive function, memory, and focus. Additionally, the antioxidant properties help protect your body from free radicals, promoting joint and skin health. With this supplement, you can feel confident in supporting your body's essential functions.

What We Like
Promotes good brain health
Improves nail health
Enhances cognitive quickness
Trusted brand with good products
Essential fats are important
What We Don't Like
Pricey for short supply
Some users still experience illness
#TOP 8

ScienceBased Health HydroEye Softgels

ScienceBased Health HydroEye Softgels Cover
HydroEye Softgels - Dry Eye Relief - Features GLA, EPA, DHA and Other Key Nutrients - 120 Count

HydroEye Softgels by ScienceBased Health is a powerful solution for dry eyes. This clinically proven supplement works from the inside out to provide support and comfort for those suffering from dry eyes. Its patented formula contains a balanced combination of GLA, EPA, DHA, and other key nutrients that are essential for maintaining a healthy tear film and ocular surface. With its unique omega fatty acid, GLA, HydroEye Softgels are much more effective than flaxseed or fish oil alone. By taking four softgels daily, you can experience the benefits of improved eye health and relief from dry eyes. Give HydroEye Softgels a try and feel the difference it can make in just a 2-month trial period.

What We Like
Recommended by eye doctors
Improves dry eye symptoms
Enhances hair and nail health
Easy to swallow capsules
Positive impact on quality of life
What We Don't Like
Cost may be hard to sustain
Mixed effectiveness reported

Bariatric Advantage OmegaVanta 10

Bariatric Advantage OmegaVanta 10 Cover
Bariatric Advantage OmegaVanta 10 - Omega Fish Oil - Enriched EPA & DHA - Enteric Softgel Design - Supports Heart Health* - Natural Lemon Flavor - 60 Softgels

Bariatric Advantage OmegaVanta 10 is a combination of purified omega-3 and omega-7 fatty acids that provides targeted support for overall cardiovascular health. With 6.6 times more EPA-DHA omega-3s than the leading krill oil, this supplement comes in an easy-to-swallow softgel with natural lemon flavor. OmegaVanta 10 is the more complete omega formula, containing both omega-3s and omega-7s, making it a perfect 10 for heart health support.

What We Like
Contains both omega-3s and omega-7s for more complete cardiovascular health support
6.6 times more EPA-DHA omega-3s than the leading krill oil
Easy-to-swallow softgel with natural lemon flavor
#TOP 10

Sports Research Omega 3 Fish Oil

Sports Research Omega 3 Fish Oil Cover
Sports Research Triple Strength Omega 3 Fish Oil - Burpless Fish Oil Supplement w/EPA & DHA Fatty Acids from Wild Alaskan Pollock - Heart, Brain & Immune Support for Men & Women - 1250 mg, 240 ct

Sports Research Omega 3 offers a high-quality fish oil supplement that is designed to be fresh and free from the unpleasant aftertaste often associated with lower-quality options. With just one softgel a day, you get a powerful dose of 1,040mg of Omega-3 fatty acids, which can support your heart and brain health. This supplement is sustainably sourced from Wild Alaska Pollock, ensuring you receive a product that is both effective and environmentally friendly. Plus, it is manufactured in a cGMP-compliant facility, giving you peace of mind about its quality and safety.

What We Like
High potency of omega-3s
No fishy aftertaste
Easy to swallow softgels
Sustainably sourced ingredients
Noticeable health benefits
What We Don't Like
Large pill size
Mild digestive discomfort initially
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What are the symptoms of lack of essential fatty acids?

A lack of essential fatty acids can manifest in various symptoms. These may include a dry scaly rash, decreased growth in infants and children, increased vulnerability to infections, and impaired wound healing. Deficiency in omega-3 fatty acids can lead to visual problems and sensory nerve disorders.

2. What are the symptoms of essential fatty acid deficiency?

Essential fatty acid deficiency is rare but can occur in infants who are fed diets lacking in essential fatty acids. Symptoms may include scaly dermatitis, hair loss (alopecia), low platelet count (thrombocytopenia), and in children, intellectual disability.

3. What are the symptoms of EFA deficiency?

EFA deficiency is rare and typically seen in infants who are fed diets deficient in essential fatty acids. Symptoms can include scaly dermatitis, hair loss (alopecia), low platelet count (thrombocytopenia), and intellectual disability in children. Diagnosis is based on clinical evaluation, and replenishing the diet with essential fatty acids can reverse the deficiency.

Editor's Notes

During our essential fatty acid combination supplement research, we found 24 essential fatty acid combination supplement products and shortlisted 10 quality products. We collected and analyzed 286,066 customer reviews through our big data system to write the essential fatty acid combination supplements list. We found that most customers choose essential fatty acid combination supplements with an average price of $26.65.

The essential fatty acid combination supplements are available for purchase. We have researched hundreds of brands and picked the top brands of essential fatty acid combination supplements, including Animal, NOW Foods, Pure Encapsulations, Swanson, ULTIMATE EFAs. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

Essential Fatty Acid Combination Supplements Comparison Table

#TOP1
#TOP2
#TOP3
#TOP4
#TOP5
#TOP6
#TOP7
#TOP8
#TOP9
#TOP10
Brand Animal NOW Foods Pure Encapsulations Swanson NOW Foods ULTIMATE EFAs Youngevity ScienceBased Health Bariatric Advantage Sports Research
Item Form Soft Gel, Capsule Softgel Softgel Softgel Liquid Softgel Capsule - Softgel Capsule
Flavor Unflavored - Unflavored - Wheat,Wheat Germ Unflavored Unflavored - Softgel Pescatarian
Unit Count 30 Count - 90.0 Count - 16 Fluid Ounces 120 Count 180.00 Count - 60.00 Count 240.0 Count
Item Weight 8 ounces - 0.01 Ounces - 16 Ounces 0.14 Kilograms 0.39 Kilograms - 0.09 Kilograms 0.99 Pounds
Product Benefits Metabolism Management - Metabolism Management - Heart Health Support Replenishing Heart Health,Supports - Heart Health Support Heart Health Support
Age Range (Description) Adult - Adult - Adult Adult Adult - Adult Adult
Item dimensions L x W x H 5 x 5 x 7 inches - 4.51 x 2.55 x 2.55 inches - 0.39 x 0.39 x 0.39 inches 2.36 x 2.36 x 4.5 inches - - 2.38 x 2.38 x 4.38 inches 3.12 x 3.12 x 6.38 inches
Package Information Canister Bottle - Bottle - - Pack - Bottle Bottle
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.5
ftb score rating icon 9.4
ftb score rating icon 9.3
ftb score rating icon 9.1
ftb score rating icon 8.9
ftb score rating icon 8.9
ftb score rating icon 8.8
Where to Buy