Best Adrenal Extract Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

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Adrenal extract supplements are a type of dietary supplement that are derived from the adrenal glands of animals such as cows, pigs, and sheep. These supplements are marketed as a way to support adrenal gland health and function, which can help to reduce stress and fatigue. Adrenal extract supplements are typically sold in pill or capsule form and are often combined with other ingredients such as vitamins, minerals, and herbs. While some people believe that adrenal extract supplements can be beneficial for managing stress and improving energy levels, there is limited scientific evidence to support these claims. As with any dietary supplement, it is important to talk to a healthcare provider before taking adrenal extract supplements.

At a Glance: Our Top Picks

Nello SuperCalm Powdered Drink Mix Cover #TOP 1
Nello SuperCalm Powdered Drink Mix
ftb score rating icon 9.8
Integrative Therapeutics Cortisol Manager Cover #TOP 2
Integrative Therapeutics Cortisol Manager
ftb score rating icon 9.7
Thorne Adrenal Cortex Capsules Cover #TOP 3
Thorne Adrenal Cortex Capsules
ftb score rating icon 9.5

Top 10 Adrenal Extract Supplements

#TOP 1

Nello SuperCalm Powdered Drink Mix

Supercalm 20 Serving Packets
Blue
Nello SuperCalm Powdered Drink Mix Cover
Nello Supercalm Powdered Drink Mix, Cortisol Reducer and Sleep Aid Supplement, L Theanine, Ksm-66 Ashwagandha, Magnesium Glycinate, Vitamin D 3, No Sugar, Non GMO, On The Go, 20 Ct, Raspberry Lemonade

Nello SuperCalm Drink Mix is designed to help you relax and focus wherever you are, thanks to its tasty raspberry lemonade flavor and convenient packaging. It supports your body's hormone balance by combining natural ingredients chosen through scientific research, helping you feel more balanced and healthy. This drink mix also promotes better sleep by including components like Ashwagandha, L Theanine, and Magnesium Glycinate, which may help you fall asleep faster and enjoy deeper rest. Additionally, it nourishes your body with essential vitamins and minerals to enhance your focus and overall well-being without sacrificing taste.

What We Like
Improved sleep quality
Helps relaxation and stress relief
Easy to mix and drink
Multiple good-tasting flavors
Supports digestive health
What We Don't Like
Flavor not for everyone
Powder may not dissolve fully
#TOP 2

Integrative Therapeutics Cortisol Manager

Integrative Therapeutics Cortisol Manager Cover
Integrative Therapeutics Cortisol Manager - Balance Cortisol & Support Relaxation for Restful Sleep* - Includes Ashwagandha & L-Theanine for Confidence with Less Stress* - 90 Tablets (45 Servings)

IT Cortisol Manager is a supplement that helps you manage stress levels and promote restful sleep. Its stress-reducing proprietary blend includes clinically studied Sensoril brand ashwagandha, which supports balanced cortisol levels and a healthy response to everyday stress. By promoting relaxation and calm, IT Cortisol Manager helps you get a good night's sleep without melatonin. Since adrenal glands play a large role in regulating stress levels, the ashwagandha extract in this supplement supports adrenal glandular health. With a new look and the same great product, IT Cortisol Manager is a convenient way to manage stress and improve sleep quality.

What We Like
Improved sleep quality
Reduced stress levels
Decreased sugar cravings
Increased daytime energy
Enhanced calmness and relaxation
What We Don't Like
Mild tiredness after extended use
Occasional headache at night

Thorne Adrenal Cortex Capsules

SG803
Thorne Adrenal Cortex Capsules Cover
THORNE - Adrenal Cortex - Supplement for Cortisol Management - Support Healthy Adrenal Gland Function, Immune System, Stress Management, Fatigue & Metabolism* - 60 Capsules

Thorne Adrenal Cortex Capsules offer support for a high-stress world by nourishing the adrenal glands, regulating metabolism and body's stress response, maintaining immune function, promoting energetic feelings, and stabilizing the stress hormone, cortisol. Thorne is a trusted brand chosen by champions and trusted by 100+ pro teams. Thorne is the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. Thorne is also a proud partner of 11 U.S. Olympic Teams.

What We Like
Improved energy and stamina
Balanced stress response
Reduced fatigue and brain fog
Stable electrolytes and hydration
High-quality clean ingredients
What We Don't Like
Possible overstimulation at higher doses
#TOP 4

Pure Encapsulations Adrenal Supplement

Pure Encapsulations Adrenal Supplement Cover
Pure Encapsulations Adrenal Cortex Supplement – Supplement to Support Cortisol Health, Energy Levels, Stress Moderation, and Gland Function – with Bovine Whole Adrenal & Cortex – 60 Capsules*

The Pure Encapsulations Adrenal Supplement is designed to provide nutritional support for healthy adrenal function. It can also help support healthy cortisol levels, fatigue, stress moderation and adrenal gland function. The supplement is made with only premium ingredients sourced from trusted suppliers and free from common allergens and unnecessary additives.

What We Like
Increased energy and alertness
Effective adrenal support
Improved stress resilience
High product quality
Recommended by health professionals
What We Don't Like
Occasional broken capsules

Garden of Life Organic Ashwagandha Supplement - 60 Tablets

103080
No Color
Garden of Life Organic Ashwagandha Supplement - 60 Tablets Cover
Garden of Life Organic Ashwagandha Supplement with Probiotics & Ginger - Stress, Mood & Energy Support, Vegan, Gluten Free, Non GMO, 2 Month Supply, 60 Tablets

Garden of Life Organic Ashwagandha Supplement is a vegan, gluten-free, and non-GMO dietary supplement that contains 600mg of organic Ashwagandha root to help promote your body's healthy stress response. It also contains probiotics and organic fermented ginger root to aid in absorption and digestive comfort. The patented clean tablet technology uses only 100% organic and non-GMO plant material to bind tablets, and the whole product is Third-party Certified USDA Organic, Non-GMO Project Verified, Vegan, NSF Gluten-Free and Kosher.

What We Like
Stress and mood support
Improved sleep quality
Increased energy levels
Organic clean ingredients
Easy to swallow capsules
What We Don't Like
Slightly large tablets
Occasional broken pills
#TOP 6

LES Labs Cortisol Health

M0UV3W1
LES Labs Cortisol Health Cover
LES Labs Cortisol Health – Stress Relief, Balanced Cortisol Response, Relaxation & Deep Sleep – Phosphatidylserine, Magnesium, Magnolia Bark, Rhodiola Rosea & Ashwagandha – Non-GMO – 60 Capsules

LES Labs Cortisol is a natural supplement that helps to promote a balanced cortisol response, which is a powerful hormone released during times of stress. This drug-free formula supports restful sleep and helps to reduce stress. The natural ingredients include phosphatidylserine, magnesium, ashwagandha, magnolia, and rhodiola root extract. Ashwagandha and rhodiola extracts help promote relaxation, while magnesium provides an added calming effect. LES Labs Cortisol is formulated to support healthy cortisol levels, which helps to promote a balanced cortisol response. Try LES Labs Cortisol today and experience the benefits of a more relaxed mind and body.

What We Like
Stress relief support
Improved sleep quality
Promotes relaxation
Affordable price
Herbal and magnesium blend
What We Don't Like
Mild discomfort for some users
Possible joint or heart effects
#TOP 7

Pure Encapsulations DHEA 10 mg Capsules

Pure Encapsulations DHEA 10 mg Capsules Cover
Pure Encapsulations DHEA 10 mg - Adrenal Supplement for Immune Support, Metabolism & Hormone Balance - with Micronized DHEA - 60 Capsules

The Pure Encapsulations DHEA Supplement supports your body's hormone balance by helping regulate fat and mineral metabolism, which is important for both men and women. This supplement provides adrenal support, assisting in the regulation of your energy levels and promoting healthy endocrine and reproductive functions. Its micronized form means it is easier for your body to absorb, so you get the benefits more efficiently. Additionally, it supports your immune system, helping you maintain overall wellness. This supplement is designed to help you feel balanced and energized while supporting your body's natural defenses.

What We Like
High purity, no fillers
Consistent lab results
Mood and energy improvement
Trusted by professionals
Gentle, minimal side effects
What We Don't Like
Slightly increased skin oiliness
Results may vary individually

Integrative Therapeutics DHEA-5

871791000681
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Integrative Therapeutics DHEA-5 Cover
Integrative Therapeutics DHEA-5 - Daily Health Supplement for Healthy Aging* - Endocrine Supplement* - Vegan, Dairy-Free & Gluten-Free - 60 Capsules (60 Servings)

Integrative DHEA-5 is a 5-mg supplement that supports healthy aging by providing adrenal and thyroid function support. DHEA is an important hormone that tends to decline with aging and increased stress, which can lead to various health problems. By taking Integrative DHEA-5, you can help maintain healthy adrenal and thyroid function. Additionally, this supplement is gluten-free, dairy-free, and vegan, making it a convenient option for people with dietary restrictions. Integrative DHEA-5 contains no wheat, gluten, corn, soy, dairy, or artificial colors, flavors, or preservatives, ensuring that you are getting a pure and natural supplement.

What We Like
Low dose option available
Improved energy levels
Affordable price
Small, easy-to-swallow capsules
Supports mood and mental clarity
What We Don't Like
Potential hormonal side effects
#TOP 9

Dr. Berg L-Theanine 200mg with Adrenal Support

Dr. Berg L-Theanine 200mg with Adrenal Support Cover
Dr. Berg L-Theanine 200mg - Includes Zinc, Copper, L-Tyrosine, & Ashwagandha – L-Theanine Supplement Adrenal Support - for Relaxation, Stress Relief, and Mental Clarity* – 90 Gelatin Capsules

Dr. Berg L-Theanine Support offers a unique blend designed to help you manage stress and improve your mood. This supplement combines high-quality minerals, amino acids, and herbs to support your energy and relaxation, helping you feel more balanced throughout the day. It also aids adrenal gland function, which can enhance your body's response to stress. The powerful formula includes a special adrenal extract along with zinc, copper, L-tyrosine, and ashwagandha, providing a comprehensive approach to mental clarity and focus. With Dr. Berg's trusted quality, you get a natural solution to help you stay calm, alert, and revitalized.

What We Like
Improved sleep quality
Reduces stress and anxiety
Promotes calm and relaxation
Enhances focus and clarity
High quality, clean formula
#TOP 10

Pure Encapsulations Cortisol Calm Capsules

Pure Encapsulations Cortisol Calm Capsules Cover
Pure Encapsulations Cortisol Calm - Supports Cortisol Health & Relaxation - Contains Ashwagandha & L-Theanine - Restful Sleep - 120 Capsules

The Pure Encapsulations Cortisol Calm is designed to help you manage stress by supporting a healthy cortisol balance, which is essential for your body's response to daily challenges. This supplement also promotes better sleep and relaxation, helping you feel more rested and positive during stressful times. It includes natural ingredients like ashwagandha and vitamin D, known for their calming and health-supporting properties. For convenience, you take one capsule in the morning and one in the evening with meals, making it easy to incorporate into your daily routine.

What We Like
Reduces stress and anxiety
Improves sleep quality
Helps manage cortisol levels
Supports weight management
No stomach discomfort
What We Don't Like
May be unsuitable for kidney or liver issues
Effects may take a week to notice
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Frequently Asked Questions (FAQs)

1. What does adrenal extract do?

Adrenal extract has been used intravenously to treat low adrenal function, high potassium levels, ulcerative colitis, and to prevent miscarriage.

2. What is adrenal supplement good for?

Adrenal supplements have potential benefits, including improved energy levels, increased mental clarity and focus, better stress management, enhanced libido, balanced moods, and improved overall health. They help regulate cortisol levels in the body.

3. What are the side effects of taking adrenal supplements?

Possible side effects of adrenal supplements include stomach irritation, nausea, anxiety, irritability, and insomnia.

4. How do I know if I need adrenal supplements?

Signs of adrenal insufficiency may include fatigue, body aches, and unexplained weight loss. If these symptoms persist, it may be worth considering adrenal supplements.

5. Does adrenal help you lose weight?

When the adrenal glands are healthy, the body can start losing fat because it no longer needs the fat to act as a hormone production center. Adrenal health can contribute to weight loss.

6. Do adrenal supplements cause weight gain?

Accidental intake of adrenal or steroid hormones can lead to weight gain, hair loss, depression, acne, and stretch marks. It can also cause a potentially life-threatening shutdown of the adrenal glands.

7. What are signs of adrenal fatigue?

Signs of adrenal fatigue may include fatigue, body aches, unexplained weight loss, low blood pressure, light-headedness, loss of body hair, and skin discoloration.

8. How does adrenal make you feel?

According to the adrenal fatigue theory, prolonged exposure to stress can lead to adrenal depletion, resulting in symptoms such as brain fog, low energy, depressive mood, salt and sweet cravings, lightheadedness, and other vague symptoms.

9. How do you know if your adrenals are struggling?

Signs of struggling adrenals may include fatigue, body aches, unexplained weight loss, low blood pressure, light-headedness, loss of body hair, and skin discoloration.

10. What are three signs of adrenal insufficiency?

Three signs of adrenal insufficiency include extreme fatigue, weight loss and loss of appetite, areas of darkened skin, low blood pressure, salt craving, low blood sugar, nausea, diarrhea or vomiting, and abdominal pain.

Editor's Notes

During our adrenal extract supplement research, we found 24 adrenal extract supplement products and shortlisted 10 quality products. We collected and analyzed 182,984 customer reviews through our big data system to write the adrenal extract supplements list. We found that most customers choose adrenal extract supplements with an average price of $27.86.

The adrenal extract supplements are available for purchase. We have researched hundreds of brands and picked the top brands of adrenal extract supplements, including Nello, Integrative Therapeutics, THORNE, Pure Encapsulations, Garden of Life. The seller of top 1 product has received honest feedback from 432 consumers with an average rating of 4.6.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

Adrenal Extract Supplements Comparison Table

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Brand Nello Integrative Therapeutics THORNE Pure Encapsulations Garden of Life LES Labs Pure Encapsulations Integrative Therapeutics Dr. Berg Nutritionals Pure Encapsulations
Item Form Powder Tablet Capsule Capsule Tablet Capsule Capsule Capsule Capsule Capsule
Unit Count 3.0 Ounce - 60.00 Count 60 Count - 60 Count 60 Count 60 Count 90 Count 120 Count
Flavor Raspberry Lemonade - Unflavored Unflavored - Herbal - Unflavored Unflavored Flavor free
Product Benefits Relaxation - Nourishing Adrenal Support - - Hypoallergenic Energy Management Sleep Support Hypoallergenic
Item Weight 89.4 Grams - 0.03 Kilograms 0.01 Ounces - - 0.01 Ounces 0.02 Kilograms - 0.24 Pounds
Package Information Packet Bottle - Bottle Bottle - Bottle Bottle - -
Primary Supplement Type Magnesium - Calcium - - Magnesium - DHEA L-Theanine -
Age Range (Description) Adult - - Adult - - Adult Adult - Adult
Department - unisex-adult - unisex-adult - - unisex-adult All Ages, Unisex - unisex-adult
Item dimensions L x W x H - - 1.83 x 1.83 x 3.22 inches 5.2 x 3.19 x 2.01 inches - - 4 x 2.3 x 1.8 inches 3.7 x 2.2 x 2.1 inches - 4 x 2.3 x 2.3 inches
FTB Score
ftb score rating icon 9.8
ftb score rating icon 9.7
ftb score rating icon 9.5
ftb score rating icon 9.5
ftb score rating icon 9.5
ftb score rating icon 9.4
ftb score rating icon 9.2
ftb score rating icon 9.2
ftb score rating icon 9.0
ftb score rating icon 8.9
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