Best Acidophilus Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

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Acidophilus supplements are a popular form of probiotics that can help maintain a healthy gut flora. These supplements contain live bacteria that are naturally present in the digestive system and can help improve digestion and boost the immune system. Acidophilus supplements are available in various forms such as capsules, tablets, and powders, and can be found in most health food stores or online. They are often recommended for people who have taken antibiotics or suffer from digestive issues such as bloating, gas, and diarrhea. It is always advisable to consult a healthcare professional before starting any new dietary supplement.

At a Glance: Our Top Picks

Physician's CHOICE Probiotics 60 Billion CFU Cover #TOP 1
Physician's CHOICE Probiotics 60 Billion CFU
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Physician's CHOICE Probiotics 60 Billion CFU Cover #TOP 2
Physician's CHOICE Probiotics 60 Billion CFU
ftb score rating icon 9.8
Nature’s Bounty Acidophilus Probiotic Cover #TOP 3
Nature’s Bounty Acidophilus Probiotic
ftb score rating icon 9.6

Top 10 Acidophilus Supplements

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Physician's CHOICE Probiotics 60 Billion CFU

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Physician's CHOICE Probiotics 60 Billion CFU Cover
Physician's Choice Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 30ct

Physician's CHOICE Probiotics 60 Billion CFU is a non-refrigerated probiotic designed to support digestive and gut health. It contains 10 diverse high-quality probiotic strains and organic prebiotics that work together to support occasional constipation, diarrhea, gas, and bloating. The probiotic is also designed to survive the gut, and is backed by scientific research, making it a great choice for those looking to support a diverse healthy microbiome.

What We Like
Gut health improvement
Bloating and constipation relief
Multiple probiotic strains
Easy to swallow capsules
Consistent results over time
What We Don't Like
Loose stools for some
No noticeable effect for a few
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Physician's CHOICE Probiotics 60 Billion CFU

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Physician's CHOICE Probiotics 60 Billion CFU Cover
Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct

Physician's CHOICE Probiotics 60 Billion CFU is a high-quality probiotic supplement designed to support digestive health and gut health. With 10 diverse probiotic strains and organic prebiotics, this probiotic is expertly crafted to support occasional constipation, diarrhea, gas, and bloating. The probiotic is designed to survive the gut and maximize the colonization of its strains, thanks to its shelf-stable bottle, acid-resistant capsules, and 60 Billion Colony forming units (CFU). Backed by scientific research and 3rd-party tested for purity and potency, this probiotic is a great choice for those looking to support a diverse healthy microbiome.

What We Like
High-potency 60 Billion CFU
10 diverse probiotic strains
Organic prebiotics included
Noticeable digestive comfort
Easy-to-swallow capsules
What We Don't Like
Small container size
Occasional delivery issues
#TOP 3

Nature’s Bounty Acidophilus Probiotic

Nature’s Bounty Acidophilus Probiotic Cover
Nature's Bounty Acidophilus Probiotic, Daily Probiotic Supplement, Digestive Health, 200 Tablets, Twin Pack

Nature's Bounty Acidophilus Probiotic is a stomach friendly supplement that provides friendly bacteria for the digestive system. It contains over 100 million active Lactobacillus Acidophilus and is free of artificial colors, flavors, and sweeteners. Customers have reported positive results in their digestion and have found the product to be worth the money. However, some customers have noted that they have to take two tablets per day instead of one.

What We Like
Easy to swallow tablets
Improved digestive health
No unpleasant taste or smell
Great value for money
Supports immune system
What We Don't Like
Limited size variety
#TOP 4

Florastor Daily Probiotic Supplement for Digestive and Immune Support (100 Capsules)

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Florastor Daily Probiotic Supplement for Digestive and Immune Support (100 Capsules) Cover
Florastor Probiotics for Digestive and Immune Health, 100 Capsules, Probiotics for Women & Men, Helps Flush Out Bad Bacteria, Boosts The Good with Our Unique Strain Saccharomyces Boulardii

Florastor Daily Probiotic Supplement is a unique probiotic with Saccharomyces boulardii lyo CNCM I-745, which helps increase the natural flora in your digestive tract and supports overall health by strengthening your digestive balance and supporting a healthy immune system. It contains 250mg of a strong probiotic strain, providing increased intestinal coverage and protection. The patented freeze-drying process gives Florastor a three-year shelf life without refrigeration, making it perfect for travelers and those with active lifestyles. The supplement is vegetarian, gluten-free, and appropriate for lactose intolerance. Florastor is an effective probiotic supplement for those who want to live a healthy lifestyle.

What We Like
Effective with antibiotics
Improves digestive health
Reduces bloating and gas
Helps prevent C. diff
High quality ingredients
What We Don't Like
Higher price point
Results may vary
#TOP 5

Nature's Bounty Ultra Strength Probiotic 10 Supplement

Nature's Bounty Ultra Strength Probiotic 10 Supplement Cover
Nature's Bounty Probiotic 10 Daily Probiotic Supplement for Digestive, Immune, and Upper Respiratory Support, Ultra Strength, 30 Capsules 1 Pack

Boost your gut health and immune system with Nature's Bounty Ultra Strength Probiotic 10 Supplement. It contains 10 unique probiotic strains that supplement the natural diversity of your GI microbiome for overall wellness. Each capsule has 20 billion CFU of good bacteria that supports digestive health and maintains a healthy gut. The one-per-day formula is easy to follow and can be taken with a meal. This gluten-free probiotic supplement has been backed by 20 years of research and 50 years of quality, making it a reliable choice for your health needs.

What We Like
Effective digestive support
Reduces bloating and gas
Easy to swallow capsules
Affordable price point
No side effects
What We Don't Like
Price could be lower
#TOP 6

Physician's CHOICE Advanced Gut Health Bundle

PB60-DE-PHYS-BUNDLE-7DD-USE
Physician's CHOICE Advanced Gut Health Bundle Cover
Physician's CHOICE Advanced Gut Health Bundle: 60 Billion Probiotics 30ct + Digestive Enzymes 60ct for Digestive, Gut, and Immune Health Supports Occasional Constipation, Diarrhea, Gas, and Bloating

The Physician's CHOICE Gut Bundle combines powerful probiotics with digestive enzymes to support your digestive health. The probiotics help balance your gut environment, which can ease common issues like constipation, diarrhea, gas, and bloating. With 60 billion CFU, these probiotics are built to survive your digestive tract and effectively colonize your gut. The digestive enzymes improve how your body breaks down food, allowing you to absorb more nutrients from your meals. Together, these ingredients promote smoother digestion, helping you feel more comfortable after eating and supporting a flatter stomach. It’s a simple, effective way to improve your gut health and overall wellness.

What We Like
Reduces bloating
Supports digestion
Helps with weight loss
No aftertaste
High-quality formula
What We Don't Like
Requires daily, consistent use
Mild side effects for some
#TOP 7

OLLY Happy Hoo-Ha Capsules

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OLLY Happy Hoo-Ha Capsules Cover
OLLY Happy Hoo-Ha Capsules, Probiotic for Women, Vaginal Health and pH Balance, 10 Billion CFU, Gluten Free - 25 Count

OLLY Happy Hoo-Ha Probiotic is a specially formulated supplement designed to support vaginal health and pH balance for women or people with vaginas. With a blend of two probiotic strains, Lactobacillus acidophilus La-14 and Lactobacillus rhamnosus HN001, this product helps restore and maintain a healthy balance of good bacteria, promoting overall vaginal health. By taking one capsule daily with water, you can easily incorporate this convenient supplement into your self-care routine. OLLY Happy Hoo-Ha Probiotic is vegetarian, free of synthetic flavors and colors, and provides 10 billion CFU per serving. Say goodbye to taboo topics and hello to a happier, healthier you with OLLY Happy Hoo-Ha Probiotic.

What We Like
No smell or weird taste
Improved vaginal health
Easy to swallow
Reduces bloating
Helps with pH balance
What We Don't Like
Small bottle size
Results vary by individual
#TOP 8

Nature's Way Probiotic Pearls Womens

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Nature's Way Probiotic Pearls Womens Cover
Nature's Way Women's Probiotic Pearls, Supports Vaginal and Digestive Health*, 1 Billion Live Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)

Nature's Way Probiotic Pearls are a daily probiotic for women that help support vaginal flora and urinary tract health. With 1 billion live probiotic cultures, these pearls help maintain vaginal and urinary tract health, promote digestive balance, and boost immune health. The active Lactobacilli cultures in the pearls are coated with a triple-layer coating, ensuring their survival to reach your small intestine, where they are most effective. The small size of these pearls makes them easy to swallow and convenient to take anywhere without the need for refrigeration. Made without gluten, yeast-derived ingredients, wheat, salt, dairy, or artificial colors, Nature's Way Probiotic Pearls are a natural and convenient way for women to support their overall well-being.

What We Like
Easy to swallow
Supports digestive health
Vaginal health benefits
No refrigeration needed
Triple-layer protection
What We Don't Like
Possible urine odor
Packaging improvement needed
#TOP 9

Garden of Life Dr. Formulated Probiotics Organic Kids+

Garden of Life Dr. Formulated Probiotics Organic Kids+ Cover
Garden of Life Dr. Formulated Probiotics Organic Kids+ plus Vitamin C & D - Berry Cherry - Gluten, Dairy & Soy Free Immune & Digestive Health Supplement, No Added Sugar, 30 Chewables (Shelf Stable)

Dr. Perlmutter formulated Organic Kids+ is a chewable probiotic supplement that supports immune system and digestive health with 5 billion CFU and 14 probiotic strains, prebiotics and Whole Food vitamins C and D. This gluten-free, dairy-free and soy-free supplement contains Lactobacillus acidophilus, gasseri, paracasei, and plantarum as well as Bifidobacterium (Bifidobacteria) lactis, breve, infantis, and bifidum for digestive health. The prebiotic supplement contains Organic Acacia fiber and whole Cranberry—prebiotics which help good bacteria in the gut thrive. It is certified Organic, Non-GMO and Vegetarian, and the probiotic potency is guaranteed through expiration.

What We Like
Great taste for kids
Supports digestion and immunity
Clean, organic ingredients
Shelf-stable and convenient
Gluten-free and dairy-free
What We Don't Like
Some kids dislike taste
Slightly chalky texture
#TOP 10

Digestive Advantage Probiotic Gummies for Digestive and Immune Health

Digestive Advantage Probiotic Gummies for Digestive and Immune Health Cover
Digestive Advantage Probiotic Gummies For Digestive Health, Vitamin D, Daily Probiotics For Women &Men Occasional Bloating, Minor Abdominal Discomfort & Gut Health, 80ct Natural Fruit Flavors

Looking for an easy and delicious way to support your digestive and immune health? Try Digestive Advantage Probiotic Gummies! These daily probiotic gummies are clinically tested to survive stomach acid 100X better than the probiotics found in yogurt. This means more good bacteria can reach your gut to help reduce minor abdominal discomfort, occasional bloating, and even relieve diarrhea. The patented BC30 probiotic interacts with your digestive system to promote overall digestive and immune health. With natural fruit flavors and 80-count per bottle, Digestive Advantage is the probiotic gummy brand of choice for men and women.

What We Like
Tasty flavor
Improved digestion
Regular bowel movements
No melting issues
Recommended by doctors
What We Don't Like
Possible melting during shipping
Buying Guide Image

Tips for Choosing the Acidophilus Supplements

What is Acidophilus?

Acidophilus is a type of beneficial bacteria that resides in the digestive system. It is part of the lactic acid bacteria family, which is known for its ability to produce lactic acid. This lactic acid helps to maintain the balance of good and bad bacteria in the gut, which is essential for overall health and wellness.

Why Take Acidophilus Supplements?

While acidophilus is naturally present in the body, there are several reasons why you may want to consider taking an acidophilus supplement. For one, the number of acidophilus bacteria in the body can be reduced due to factors such as stress, illness, and certain medications. Additionally, the modern diet, which is often high in processed and sugary foods, can also reduce the levels of acidophilus in the body.

Taking an acidophilus supplement can help to restore the balance of good bacteria in the gut, which can support a healthy digestive system. Acidophilus supplements can also help to support the immune system and may even have a positive effect on overall health and wellbeing.

Choosing an Acidophilus Supplement

When it comes to choosing an acidophilus supplement, there are a few things to consider. First, it's important to choose a supplement that contains a high number of live bacteria. This is because the beneficial effects of acidophilus are dependent on the number of live bacteria present in the supplement.

Another factor to consider is the type of bacteria used in the supplement. Some supplements use a single strain of acidophilus bacteria, while others use a blend of multiple strains. While there is no clear consensus on which is better, some research suggests that a blend of multiple strains may be more effective at supporting gut health.

It's also important to choose an acidophilus supplement that is manufactured using high-quality standards. Look for supplements that are made using GMP (Good Manufacturing Practices) and are third-party tested for quality and purity.

Finally, consider the form of the supplement. Acidophilus supplements are available in a variety of forms, including capsules, tablets, powders, and liquids. Some people may prefer one form over another, so it's a good idea to experiment to find the one that works best for you.

Conclusion

Acidophilus supplements can be a great way to support a healthy digestive system and maintain the balance of good bacteria in the gut. When choosing an acidophilus supplement, look for a product that contains a high number of live bacteria, is made using high-quality standards, and comes in a form that is convenient for you to take. With so many options available, you're sure to find an acidophilus supplement that meets your needs.

Frequently Asked Questions (FAQs)

1. What are the benefits of taking acidophilus?

Taking acidophilus as a supplement or consuming it through certain foods like yogurt can provide several benefits. Acidophilus is commonly used to treat vaginal inflammation (bacterial vaginosis) and digestive disorders. It also promotes the growth of good bacteria in the body.

2. Is it OK to take acidophilus daily?

In general, taking acidophilus daily is considered safe for most individuals. However, some people may experience side effects like gas, upset stomach, and diarrhea when taking more than 1 to 2 billion L. acidophilus CFUs daily. It's important to consult with a healthcare professional before starting any new supplement regimen.

3. Is it better to take acidophilus or probiotics?

Acidophilus is a type of probiotic that offers specific benefits. Studies suggest that L. acidophilus may be more effective than other types of probiotics in reducing cholesterol levels. However, the choice between acidophilus and other probiotics depends on individual needs and health conditions.

4. When should I take acidophilus probiotics?

To improve the survival rates of probiotics through stomach acid, it's recommended to take them on an empty stomach. Many people take acidophilus probiotics first thing in the morning, about 30 minutes before breakfast, or 2-3 hours after the last meal in the evening. Consistency in timing is key.

5. Does acidophilus help with belly fat?

In a study, the combination of Lactobacillus acidophilus with other strains and a healthy diet resulted in reduced polyunsaturated fatty acids and a slimmer waist circumference in women. However, it's important to note that individual results may vary and a comprehensive approach to weight management is recommended.

6. How long does it take for acidophilus to work?

If you are taking a high-quality, multispecies, and multistrain acidophilus supplement, you may notice initial improvements in digestion and health benefits within the first 1-2 weeks. Individual sensitivity may vary, and some people may experience a difference in just a few days.

7. When should you not take acidophilus?

If you develop signs of an infection such as fever or chills, it's important to stop taking acidophilus and seek immediate medical guidance. Additionally, if you experience signs of a serious allergic reaction, such as rash, swelling, or trouble breathing, it's recommended to discontinue use and seek medical attention.

8. Are there any side effects from taking acidophilus?

While rare, a serious allergic reaction to acidophilus can occur. If you notice symptoms like rash, itching, swelling (especially of the face, tongue, or throat), dizziness, or trouble breathing, it's important to seek medical help immediately. This is not an exhaustive list of possible side effects, and it's advisable to consult a healthcare professional.

9. What naturally kills bad bacteria in the gut?

To address bad bacteria in the gut, several strategies can be employed. These include adopting an anti-inflammatory diet, engaging in regular exercise, prioritizing good quality sleep, and incorporating probiotics into the routine. These measures can help promote a healthy balance of bacteria in the gut before considering antimicrobials or antibiotics.

Editor's Notes

During our acidophilus supplement research, we found 24 acidophilus supplement products and shortlisted 10 quality products. We collected and analyzed 1,280,722 customer reviews through our big data system to write the acidophilus supplements list. We found that most customers choose acidophilus supplements with an average price of $24.00.

The acidophilus supplements are available for purchase. We have researched hundreds of brands and picked the top brands of acidophilus supplements, including Physician's CHOICE, Nature's Bounty, Florastor, OLLY, Nature's Way. The seller of top 1 product has received honest feedback from 6,426 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.

Acidophilus Supplements Comparison Table

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Brand Physician's CHOICE Physician's CHOICE Nature's Bounty Florastor Nature's Bounty Physician's CHOICE OLLY Nature's Way Garden of Life Digestive Advantage
Flavor 60B Probiotic 60B Probiotic Unflavored Unflavored Unflavored Unflavored Happy Hoo-Ha Unflavored Berry Cherry Natural Fruit
Unit Count 30 Count 60 Count 200 Count 100 Count 30 Count 90.0 Count 25 Count 30 Count 30 Count 80 Count
Item Form Capsule Capsule Tablet Capsule Capsule Capsule Capsule Softgel Chewable Gummy
Item dimensions L x W x H 4.5 x 2.4 x 2.4 inches 3 x 3 x 5.5 inches 1.97 x 3.94 x 4.07 inches 4.13 x 2.09 x 5.24 inches 3 x 2.38 x 3.31 inches - 2.09 x 1.05 x 4.17 inches 1 x 3.5 x 4.81 inches 2.32 x 2.32 x 4.63 inches 3.06 x 3.06 x 5.51 inches
Product Benefits Digestive Health Support, Gut Health, Occasional Constipation, Diarrhea, Gas & Bloating Digestive Health Support, Gut Health, Occasional Constipation, Diarrhea, Gas & Bloating Digestive Health Support Digestive Health Support, Immune Support Digestive Health Support - pH Balance Digestive Health Support, Immune Support, Stress Relief Digestive Health Support, Immune Support Immune Support,Digestive Health
Item Weight 0.15 Pounds - 0.2 Pounds 6.3 Ounces 0.13 Pounds - 0.09 Pounds 0.03 Pounds 0.21 Pounds 0.73 Pounds
Special Ingredients Acidophilus - Lactobacillus acidophilus Saccharomyces Boulardii CNCM I-745 proprietary probiotic blend - A blend of powerful probiotics Probiotic Acidophilus Probiotic
Diet Type - Vegan Gluten Free Gluten Free Vegetarian - Vegetarian Gluten Free Gluten Free Gluten Free
Primary Supplement Type - - Lactobacillus acidophilus Probiotic proprietary probiotic blend Probiotic Probiotic Probiotic Probiotic protein
FTB Score
ftb score rating icon 9.9
ftb score rating icon 9.8
ftb score rating icon 9.6
ftb score rating icon 9.4
ftb score rating icon 9.3
ftb score rating icon 9.1
ftb score rating icon 8.9
ftb score rating icon 8.8
ftb score rating icon 8.8
ftb score rating icon 8.8
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