Best Prebiotic Acidophilus Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Prebiotic Acidophilus Supplements are a type of dietary supplement that contain acidophilus, a type of probiotic bacteria that is naturally found in the human gut. These supplements are designed to help support digestive health by promoting the growth of beneficial bacteria in the gut. In addition to acidophilus, prebiotic acidophilus supplements may also contain other types of probiotics and prebiotics, which can help to further enhance their digestive health benefits. These supplements are available in a variety of forms, including capsules, tablets, and powders, and are often recommended for individuals who are looking to improve their overall digestive health or who are experiencing digestive issues such as bloating, gas, or constipation.

At a Glance: Our Top Picks

Nature's Nutrition Probiotic 80 Billion CFU Cover #TOP 1
Nature's Nutrition Probiotic 80 Billion CFU
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Built by Nature 80 Billion CFU Probiotic Cover #TOP 2
Built by Nature 80 Billion CFU Probiotic
ftb score rating icon 9.8
Igennus Live Cultures+ Cover #TOP 3
Igennus Live Cultures+
ftb score rating icon 9.6

Top 10 Prebiotic Acidophilus Supplements

#TOP 1

Nature's Nutrition Probiotic 80 Billion CFU

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Nature's Nutrition Probiotic 80 Billion CFU Cover
Probiotic Supplement 80 Billion CFU + Prebiotics, Acidophilus Probiotic Supports Immune System & Digestive Health, Supports Occasional Constipation, Supplement for Women Feminine Health - 120 Capsules

Nature's Nutrition Probiotic is designed to enhance your digestive health with a potent blend of 80 billion CFU, including Lactobacillus acidophilus. This probiotic formula not only aids in maintaining a balanced gut flora but also improves nutrient absorption, which can lead to better overall health. Additionally, it supports your immune system, helping you stay strong and healthy. Specifically formulated for women, this supplement promotes healthy vaginal flora, ensuring comfort and hygiene. You can trust this non-GMO, artificial ingredient-free formula to support your wellness needs without compromise.

What We Like
Supports digestive health
Boosts immune system
Formulated for women's health
Non-GMO and pure

Built by Nature 80 Billion CFU Probiotic

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Built by Nature 80 Billion CFU Probiotic Cover
90 Billion CFU Probiotic - Daily Digestive Gut Health Supplement for Men & Women - Lactobacillus acidophilus, Bifidobacterium & Prebiotics - Non-GMO, Gluten & Dairy Free, Shelf-Stable - 60 Capsules

Built by Nature Probiotic is a high-strength supplement formulated to support gut health and enhance digestive function. Designed for both men and women, this daily supplement provides comprehensive digestive and gut health support. It contains beneficial strains such as Lactobacillus acidophilus and Bifidobacterium, which are known for their gut-friendly properties. Additionally, the formula includes prebiotics to nourish the probiotics and promote a healthy gut flora. With its non-GMO, gluten-free, and dairy-free composition, this product is suitable for individuals with specific dietary restrictions.

What We Like
High-Strength Probiotic
Designed for Men and Women
Enriched with Beneficial Strains
#TOP 3

Igennus Live Cultures+

Igennus Live Cultures+ Cover
Live Cultures+ Lab4 Probiotics & Prebiotic, Lactobacillus Acidophilus & Bifidobacterium, Guaranteed 25 Billion CFU,Vegan, Non-Bloating Gut Health Support, Non-GMO, 30 Capsules, by Igennus

Igennus Live Cultures+ Lab4 Probiotics & Prebiotic is a comprehensive gut health support supplement designed to restore gut health and support digestion for both men and women. With a guaranteed 25 billion CFU at expiry, this supplement provides a powerful dose of probiotics. The Lab4 strains, including Lactobacillus and Bifidobacterium, have been clinically proven to support symptoms of IBS and constipation. The non-bloating prebiotic Aquamin calcium acts as a protective carrier, ensuring more live strains reach the intestines. These acid-resistant strains are microencapsulated for enhanced stability and do not require refrigeration. With its vegan, clean label formulation, Igennus Live Cultures+ is suitable for a variety of dietary needs and preferences.

What We Like
Comprehensive gut health support
Clinically proven strains
Non-bloating prebiotic

Proriginal Probiotics 100 Billion CFU

60 Count/30 Days Supply
Proriginal Probiotics 100 Billion CFU Cover
Probiotics with Prebiotics for Men and Women - 35 Strains Organic Probiotic 100 Billion CFU for Gut & Digestive Health, Vegan Acidophilus Probiotic Supplement, Non-GMO Raw Probiotic 60 Capsules

Proriginal Probiotics 100 Billion CFU is a high-quality probiotic supplement designed for both men and women. With 35 strains of probiotics, 5 prebiotics, 7 digestive enzymes, and citrus bioflavonoids, this probiotic is specifically formulated to support gut and digestive health. It helps relieve issues such as gas, bloating, and constipation, while also supporting the immune system and overall health. The delayed release technology ensures the probiotics reach the intestinal tract, providing maximum effectiveness. Made in the USA, this probiotic is tested for purity and potency, guaranteeing safety and quality. Try Proriginal Probiotics 100 Billion CFU for improved gut health and overall well-being.

What We Like
Supports gut and digestive health
Contains 35 strains of probiotics
Free of allergens like gluten and soy
Helps with weight loss and increased energy
Reduces bloating and improves overall gut health
#TOP 5

Swanson L. Reuteri Probiotic Plus

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Swanson L. Reuteri Probiotic Plus Cover
Swanson L. Reuteri Probiotic Plus w/L. Rhamnosus L. Acidophilus & FOS Prebiotic Digestive Support - Promotes Gut Health w/ 7 Billion CFU per Capsule - (30 Veggie Capsules)

Swanson Probiotic Plus is designed to support your digestive health effectively. This supplement releases its beneficial ingredients directly in the lower gastrointestinal tract, ensuring that you receive optimal benefits. With a powerful blend of 7 billion CFUs, including L. Reuteri, L. rhamnosus, and L. acidophilus, it provides comprehensive digestive support. Taking one veggie capsule daily with water is simple and convenient, making it easy to incorporate into your routine. Plus, Swanson's commitment to quality means you can trust the purity and potency of each capsule, backed by decades of expertise in health products.

What We Like
Supports digestive health
High probiotic count
Easy daily dosage
Trusted brand quality
#TOP 6

BioSchwartz Probiotic 65 Billion Capsules

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BioSchwartz Probiotic 65 Billion Capsules Cover
Probiotic 65 Billion - Probiotics with Prebiotic for Women & Men - Lactobacillus Acidophilus Digestive Health Capsules - Targeted Release Technology - Shelf Stable Supplement Non-GMO Dairy Free-30ct

BioSchwartz Probiotic Capsules offer robust digestive support with 65 billion CFUs and 13 probiotic strains to help you maintain a healthy gut. This doctor-approved formula is designed to withstand stomach acid, ensuring that beneficial bacteria reach your small and large intestines, promoting better nutrient absorption. Each batch is purity tested and free from common allergens like gluten and soy, giving you peace of mind about what you're taking. Manufactured in the USA with high-quality ingredients, you can trust that these capsules meet strict quality standards for your health.

What We Like
High CFU count
Doctor-approved formula
Allergen-free
Quality tested
#TOP 7

BioSchwartz 40 Billion CFU Probiotic Supplement for Gut Health

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BioSchwartz 40 Billion CFU Probiotic Supplement for Gut Health Cover
Daily Probiotic Supplement with 40 Billion CFU - Gut Health Complex with Astragalus and Lactobacillus Acidophilus Probiotic for Women and Men - Shelf Stable Pre and Probiotics for Digestive Health

Looking for a complete solution for your digestive health? Try BioSchwartz's Daily Probiotic Supplement with 40 Billion CFU. Featuring a cutting-edge delivery system, professional-grade lactobacillus and bifidobacterium, and astragalus for enhanced immunity, this supplement is formulated to provide lasting relief and balance for a variety of concerns. With gentle, easy-to-swallow capsules that are gluten-free and allergen-free, BioSchwartz sets a higher standard for gut health supplements.

What We Like
Contains lactobacillus and bifidobacterium for complete digestive support
Features a protective patented delay release system for lasting relief and balance
Includes astragalus for enhanced immunity
Gluten-free and allergen-free capsules

21st Century Acidophilus Capsules, 100 Count (21339)

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21st Century Acidophilus Capsules, 100 Count (21339) Cover
21st Century Acidophilus Capsules, 100 Count (21339)

The 21st Century Acidophilus Capsules are a great choice for anyone looking to support healthy digestion and optimal nutrition. These probiotic capsules are designed to aid in the maintenance of probiotic activity in the intestine, making them a great addition to any diet. Please note that this product is not intended to diagnose, treat, cure, or prevent any disease. During the summer months, the product may arrive warm, but Amazon follows the manufacturer's recommendations when storing and shipping products.

What We Like
Supports healthy digestion and optimal nutrition
Designed to maintain probiotic activity in the intestine
Well-rounded supplementation program for any diet
#TOP 9

Physician's CHOICE Probiotics 60 Billion CFU

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Physician's CHOICE Probiotics 60 Billion CFU Cover
Physician's CHOICE Probiotics 60 Billion CFU - 10 Strains + Organic Prebiotics - Immune, Digestive & Gut Health - Supports Occasional Constipation, Diarrhea, Gas & Bloating - for Women & Men - 60ct

Physician's CHOICE Probiotics 60 Billion CFU is a high-quality probiotic supplement designed to support digestive health and gut health. With 10 diverse probiotic strains and organic prebiotics, this probiotic is expertly crafted to support occasional constipation, diarrhea, gas, and bloating. The probiotic is designed to survive the gut and maximize the colonization of its strains, thanks to its shelf-stable bottle, acid-resistant capsules, and 60 Billion Colony forming units (CFU). Backed by scientific research and 3rd-party tested for purity and potency, this probiotic is a great choice for those looking to support a diverse healthy microbiome.

What We Like
High CFU count
Wide range of probiotic strains
Vegan formula
#TOP 10

Solaray Acidophilus Probiotic

2663068
30 Count
Solaray Acidophilus Probiotic Cover
Solaray Acidophilus 3 Strain Probiotic & Prebiotic Carrot Juice | 3 Billion CFU, Vegan & Freeze Dried | 30 VegCaps

Solaray Probiotic Capsules are designed to support your gut health with a blend of over 3 billion living probiotic cells in each capsule. The addition of carrot juice powder acts as a prebiotic, enhancing the effectiveness of the probiotics. Made in a trusted facility, these capsules are non-GMO, vegan, and lab-verified for purity and potency, ensuring you get quality you can rely on. They are also formulated to withstand shipping without refrigeration for up to a week, making it convenient for you to receive your probiotics even in extreme heat. Plus, the 60-day money-back guarantee gives you peace of mind.

What We Like
High probiotic count
Prebiotic support
Non-GMO and vegan
Formulated for shipping
Money-back guarantee
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Frequently Asked Questions (FAQs)

1. Is acidophilus a probiotic or prebiotic?

Overview. Acidophilus (Lactobacillus acidophilus), a bacterium found in the mouth, intestine and vagina, is used as a probiotic. Probiotics are good bacteria that are either the same as or very similar to the bacteria that are already in your body.

2. What are the benefits of taking acidophilus?

Acidophilus may be used as a probiotic to promote the growth of good bacteria in your body. Acidophilus may also help treat a variety of medical conditions such as digestive issues, yeast infections and eczema.

3. What is difference between probiotics and acidophilus?

The main difference between acidophilus and Probiotic is that acidophilus is a type of probiotics that lives in the elementary tract of animals whereas probiotic is a good bacterium that protects the body against disease-causing bacteria.

4. Is it OK to take acidophilus daily?

Lactobacillus acidophilus is generally considered safe for most people. Gas, upset stomach, and diarrhea are potential side effects in some people (not on antibiotic therapy) who take more than 1 to 2 billion L. acidophilus CFUs daily.

Editor's Notes

During our prebiotic acidophilus supplement research, we found 24 prebiotic acidophilus supplement products and shortlisted 10 quality products. We collected and analyzed 608,424 customer reviews through our big data system to write the prebiotic acidophilus supplements list. We found that most customers choose prebiotic acidophilus supplements with an average price of $19.12.

The prebiotic acidophilus supplements are available for purchase. We have researched hundreds of brands and picked the top brands of prebiotic acidophilus supplements, including Nature's Nutrition, Built by Nature, Igennus Healthcare Nutrition, Proriginal, Swanson. The seller of top 1 product has received honest feedback from 8,631 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.