Best Prebiotic Acidophilus Supplements of 2026

Physician's CHOICE Probiotics 60 Billion CFU is a non-refrigerated probiotic designed to support digestive and gut health. It contains 10 diverse high-quality probiotic strains and organic prebiotics that work together to support occasional constipation, diarrhea, gas, and bloating. The probiotic is also designed to survive the gut, and is backed by scientific research, making it a great choice for those looking to support a diverse healthy microbiome.

Garden of Life Dr. Formulated Probiotics for Women & Prebiotics is a 50 Billion CFU probiotic supplement specifically designed for women's daily digestive, vaginal, and immune health. It contains 16 probiotic strains that are shelf stable, gluten-free, dairy-free, and soy-free. It also contains organic prebiotic fiber to help feed good bacteria in the gut. Customers have reported feeling more energized and clear-headed after taking the product, as well as relief from bloating and other digestive issues.

Physician's CHOICE Probiotics 60 Billion CFU is a high-quality probiotic supplement designed to support digestive health and gut health. With 10 diverse probiotic strains and organic prebiotics, this probiotic is expertly crafted to support occasional constipation, diarrhea, gas, and bloating. The probiotic is designed to survive the gut and maximize the colonization of its strains, thanks to its shelf-stable bottle, acid-resistant capsules, and 60 Billion Colony forming units (CFU). Backed by scientific research and 3rd-party tested for purity and potency, this probiotic is a great choice for those looking to support a diverse healthy microbiome.

NewRhythm Probiotics is a 100% natural, non-GMO, gluten-free probiotics supplement made in New York, USA. It features a targeted release formula with 50 billion living organisms per serving and 20 strains, including organic prebiotics fiber. This potent and pure formula supports the establishment and maintenance of favorable intestinal flora, providing powerful support for healthy digestion and balanced intestinal ecology. The capsules are scientifically backed and clinically proven to survive stomach acids and reach your intestinal track, thanks to the targeted release technology. The product is shelf-stable and doesn't require refrigeration, making it convenient for everyday use. Moreover, the product is independently tested in 3rd party labs in the USA, ensuring its quality and purity. If you are not completely satisfied with the product, you can take advantage of the 100% satisfaction guarantee within 30 days.

OMOGS Probiotic is a powerful women's probiotic supplement that offers a range of benefits for digestive, gut, immune, and women's health. With 90 billion CFUs and 18 probiotic strains per serving, it helps restore your digestive system and gut health, boost your immunity, and support overall women's health. The blend of probiotic strains in each tablet is specially formulated to withstand stomach acid and ensure all strains are released in the intestines. This can help ease occasional bloating, constipation, and digestive discomfort, while also creating an ideal intestinal environment. Additionally, OMOGS Probiotic contains cranberry extract to promote urinary tract health and Lactobacillus reuteri to support vaginal health. With organic prebiotics and natural vegan probiotics, this supplement also provides immune system support. Made in the USA and GMP certified, OMOGS Probiotic is gluten-free, dairy-free, soy-free, and free from artificial dyes, ensuring quality, purity, and potency.

Dr. Perlmutter formulated Organic Kids+ is a chewable probiotic supplement that supports immune system and digestive health with 5 billion CFU and 14 probiotic strains, prebiotics and Whole Food vitamins C and D. This gluten-free, dairy-free and soy-free supplement contains Lactobacillus acidophilus, gasseri, paracasei, and plantarum as well as Bifidobacterium (Bifidobacteria) lactis, breve, infantis, and bifidum for digestive health. The prebiotic supplement contains Organic Acacia fiber and whole Cranberry—prebiotics which help good bacteria in the gut thrive. It is certified Organic, Non-GMO and Vegetarian, and the probiotic potency is guaranteed through expiration.

Garden of Life Dr. Formulated Probiotics Mood+ is a probiotic supplement that provides 50 Billion CFU and 16 Probiotic Strains, plus 350 mg of Organic Ashwagandha and Alaskan Blueberry for stress management. It is Non-GMO Project Verified and NSF Certified Gluten Free, and is designed to support emotional well-being, relaxation, and digestive balance. Customers have reported improved bowel movements, reduced nocturnal pruritis, and improved mental health.

Hyperbiotics Pro 15 Probiotic is a vegan probiotic supplement that is designed to support digestive and immune system health. With 15 targeted probiotic strains, including Lactobacillus, Bifidobacterium, and Streptococcus, this formula helps replenish beneficial bacteria in your gut. The probiotic organisms are released over an 8-10 hour period, bypassing stomach acids and reaching deep into your intestinal tract alive. This allows you to experience the full benefits of probiotics. The convenient regimen involves taking just one small pearl-shaped tablet per day, with no refrigeration necessary. The formula is vegan, non-GMO, and gluten-free, and it is tested for safety and potency. Manufactured in the USA, Hyperbiotics Pro 15 Probiotic follows strict quality control and FDA guidelines, ensuring its purity and efficacy.

Garden of Life's Once Daily Prenatal Probiotic provides 20 Billion CFU and 16 Probiotic Strains plus Prebiotic Fiber for pregnant and lactating women. This hypoallergenic probiotic supplement includes Lacto and Bifido strains, with 115mg Organic Potato and Organic Acacia prebiotic fiber to help feed good bacteria in the gut. It is shelf-stable, no need to refrigerate, and third-party certified Non-GMO and Gluten-Free.