Best Natural Acidophilus Supplements of 2026

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 27, 2026

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Natural Acidophilus Supplements are a type of probiotic that contain live bacteria that are beneficial to the digestive system. These supplements are designed to help balance the natural bacteria in the gut, which can be disrupted by factors such as diet, stress, and antibiotics. Acidophilus supplements are particularly useful for individuals who suffer from digestive issues such as bloating, gas, or constipation. Additionally, they can help boost the immune system and improve overall gut health. These supplements come in various forms, including capsules, tablets, and powders, and can be found at most health food stores.

At a Glance: Our Top Picks

Digestive Advantage Probiotic Gummies for Digestive and Immune Health Cover #TOP 1
Digestive Advantage Probiotic Gummies for Digestive and Immune Health
ftb score rating icon 9.9
Nature’s Bounty Acidophilus Probiotic Cover #TOP 2
Nature’s Bounty Acidophilus Probiotic
ftb score rating icon 9.8
NewRhythm Probiotics 50 Billion CFU 20 Strains Cover #TOP 3
NewRhythm Probiotics 50 Billion CFU 20 Strains
ftb score rating icon 9.6

Top 9 Natural Acidophilus Supplements

Digestive Advantage Probiotic Gummies for Digestive and Immune Health

Digestive Advantage Probiotic Gummies for Digestive and Immune Health Cover
Digestive Advantage Probiotic Gummies For Digestive Health, Vitamin D, Daily Probiotics For Women &Men Occasional Bloating, Minor Abdominal Discomfort & Gut Health, 80ct Natural Fruit Flavors

Looking for an easy and delicious way to support your digestive and immune health? Try Digestive Advantage Probiotic Gummies! These daily probiotic gummies are clinically tested to survive stomach acid 100X better than the probiotics found in yogurt. This means more good bacteria can reach your gut to help reduce minor abdominal discomfort, occasional bloating, and even relieve diarrhea. The patented BC30 probiotic interacts with your digestive system to promote overall digestive and immune health. With natural fruit flavors and 80-count per bottle, Digestive Advantage is the probiotic gummy brand of choice for men and women.

What We Like
Tasty flavor
Improved digestion
Regular bowel movements
No melting issues
Recommended by doctors
#TOP 2

Nature’s Bounty Acidophilus Probiotic

Nature’s Bounty Acidophilus Probiotic Cover
Nature's Bounty Acidophilus Probiotic, Daily Probiotic Supplement, Digestive Health, 200 Tablets, Twin Pack

Nature's Bounty Acidophilus Probiotic is a stomach friendly supplement that provides friendly bacteria for the digestive system. It contains over 100 million active Lactobacillus Acidophilus and is free of artificial colors, flavors, and sweeteners. Customers have reported positive results in their digestion and have found the product to be worth the money. However, some customers have noted that they have to take two tablets per day instead of one.

What We Like
Easy to swallow tablets
Improved digestive health
No unpleasant taste or smell
Great value for money
Supports immune system
#TOP 3

NewRhythm Probiotics 50 Billion CFU 20 Strains

N7P60
NewRhythm Probiotics 50 Billion CFU 20 Strains Cover
NewRhythm Probiotics 50 Billion CFU 20 Strains, 60 Veggie Capsules, Targeted Release Technology, Stomach Acid Resistant, No Need for Refrigeration, Non-GMO, Gluten Free

NewRhythm Probiotics is a 100% natural, non-GMO, gluten-free probiotics supplement made in New York, USA. It features a targeted release formula with 50 billion living organisms per serving and 20 strains, including organic prebiotics fiber. This potent and pure formula supports the establishment and maintenance of favorable intestinal flora, providing powerful support for healthy digestion and balanced intestinal ecology. The capsules are scientifically backed and clinically proven to survive stomach acids and reach your intestinal track, thanks to the targeted release technology. The product is shelf-stable and doesn't require refrigeration, making it convenient for everyday use. Moreover, the product is independently tested in 3rd party labs in the USA, ensuring its quality and purity. If you are not completely satisfied with the product, you can take advantage of the 100% satisfaction guarantee within 30 days.

What We Like
Effective for chronic constipation
Improved digestive health
Stomach acid resistant capsules
No refrigeration required
Good value for money

Nature's Way Probiotic Pearls Womens

04213
Nature's Way Probiotic Pearls Womens Cover
Nature's Way Women's Probiotic Pearls, Supports Vaginal and Digestive Health*, 1 Billion Live Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)

Nature's Way Probiotic Pearls are a daily probiotic for women that help support vaginal flora and urinary tract health. With 1 billion live probiotic cultures, these pearls help maintain vaginal and urinary tract health, promote digestive balance, and boost immune health. The active Lactobacilli cultures in the pearls are coated with a triple-layer coating, ensuring their survival to reach your small intestine, where they are most effective. The small size of these pearls makes them easy to swallow and convenient to take anywhere without the need for refrigeration. Made without gluten, yeast-derived ingredients, wheat, salt, dairy, or artificial colors, Nature's Way Probiotic Pearls are a natural and convenient way for women to support their overall well-being.

What We Like
Easy to swallow
Supports digestive health
Vaginal health benefits
No refrigeration needed
Triple-layer protection
#TOP 5

OMOGS Women's Probiotic

OMOGS-W-P
90 Count
OMOGS Women's Probiotic Cover
OMOGS Women's Probiotic, with Cranberry Extract, Organic Prebiotics & Vitamin C, 90 Billion CFUs,18 Strains, Help for Boost Immune, Digestive, Gut Health & Women's Health, Gluten & Soy Free,90 Tablets

OMOGS Probiotic is a powerful women's probiotic supplement that offers a range of benefits for digestive, gut, immune, and women's health. With 90 billion CFUs and 18 probiotic strains per serving, it helps restore your digestive system and gut health, boost your immunity, and support overall women's health. The blend of probiotic strains in each tablet is specially formulated to withstand stomach acid and ensure all strains are released in the intestines. This can help ease occasional bloating, constipation, and digestive discomfort, while also creating an ideal intestinal environment. Additionally, OMOGS Probiotic contains cranberry extract to promote urinary tract health and Lactobacillus reuteri to support vaginal health. With organic prebiotics and natural vegan probiotics, this supplement also provides immune system support. Made in the USA and GMP certified, OMOGS Probiotic is gluten-free, dairy-free, soy-free, and free from artificial dyes, ensuring quality, purity, and potency.

What We Like
90 Billion CFUs, 18 Strains
Cranberry Extract for Urinary Tract Health
Digestive Comfort and Intestinal Harmony
#TOP 6

NOW Foods Supplements, Probiotic-10™, 25 Billion

2926
Peach Beige
NOW Foods Supplements, Probiotic-10™, 25 Billion Cover
NOW Foods Supplements, Probiotic-10™, 25 Billion, with 10 Probiotic Strains, Dairy, Soy and Gluten Free, Strain Verified, 50 Veg Capsules

Features
10 PROBIOTIC STRAINS: Offers A Balanced Spectrum Of Live Organisms Consisting Of Acid-Resistant Probiotic Bacterial Strains That Are Known To Naturally Colonize The Human GI Tract*
CLINICALLY VALIDATED STRAINS*: Utilizes Bacterial Strains That Have Been Clinically Validated For Their Support Of Healthy Immune System Function*
HEALTHY INTESTINAL FLORA*: Probiotic Bacteria Are Critical For Healthy Digestion, Helping Maintain The Integrity Of The Intestinal Lining, Support Proper Intestinal Motility, And Participate In The Detoxification Process*
GMP Quality Assured: NPA A-Rated GMP Certification Means That Every Aspect Of The NOW Manufacturing Process Has Been Examined, Including Our Laboratory/testing Methods (for Stability, Potency, And Product Formulation)
Packaged In The USA By A Family Owned And Operated Company Since 1968
#TOP 7

OLLY Probiotic Gummy

OLLY Probiotic Gummy Cover
OLLY Probiotic Gummy, 1 Billion CFUs, Immune and Digestive Support, Chewable Probiotic Supplement, Mango, 80 Count

OLLY Probiotic Mango Gummies are packed with one billion live cultures of bacillus coagulans, supporting your gut flora and immune system. These tasty gummies help keep your digestive tract healthy, making you feel your best. OLLY aims to simplify nutrition, ensuring you can easily maintain good health. Their gummy vitamins and supplements are not only effective but also enjoyable to consume, fitting seamlessly into your daily routine.

What We Like
1 Billion CFUs
Supports Gut Flora
Easy to Consume
#TOP 8

Organic Probiotics for Digestive Health

MARYRUTH'S
4 Fl Oz (Pack of 1)
Organic Probiotics for Digestive Health Cover
MaryRuth Organics USDA Organic Liquid Probiotic | Digestive Health | Gut Health | Probiotics for Women | Probiotics for Men | Probiotics for Kids | Acidophilus Probiotic | Non-GMO | 40 Servings

Looking for a natural way to support your immune system and digestive health? MaryRuth's Liquid Probiotic is USDA Organic and Vegan, formulated to help support a healthy microbiome and digestive tract with a blend of 12 probiotic strains. The acidophilus probiotic helps promote gut lining health which supports a robust immune system. The suggested use is simple: shake gently before use, take directly by mouth or with liquid, and avoid hot liquids to preserve efficacy. The travel-friendly 2 oz bottle is perfect for on-the-go use, and the simple ingredients are dairy-free, nut-free, gluten-free, soy-free, and sugar-free.

What We Like
Effective for gut health
Tasteless and easy to consume
Good for kids' use
Positive customer service experience
Convenient liquid form
#TOP 9

Florastor Kids Probiotic Supplement

68268
Florastor Kids Probiotic Supplement Cover
Florastor Kids Dual Action Probiotic Supplement, Strengthens Kids' Digestive & Immune Health, 20 Easy-to Mix Powder Sticks, Packaging May Vary

Florastor Kids Daily Probiotic Supplement is an unflavored powder that is perfect for children aged 2 months and up. It is formulated to help your child maintain healthy digestion and support their immune system. The probiotic is resistant to 16 of the most commonly used oral antibiotics and does not require refrigeration. Florastor is the number one probiotic in its class worldwide, using a unique and effective probiotic strain that has been researched for over 65 years. This probiotic supplement is vegetarian, gluten-free, titanium dioxide-free, and appropriate for lactose intolerance.

What We Like
Resistant to 16 common oral antibiotics
Supports digestive and immune system health
Number one probiotic in its class worldwide
Vegetarian, gluten-free, titanium dioxide-free, and appropriate for lactose intolerance
Buying Guide Image

Frequently Asked Questions (FAQs)

1. How can I get acidophilus naturally?

acidophilus can be found naturally in a number of fermented foods, including sauerkraut, miso and tempeh. Also, it's added to other foods like cheese and yogurt as a probiotic.

2. What is the purpose of taking acidophilus?

People commonly take acidophilus to treat a type of vaginal inflammation (bacterial vaginosis) and digestive disorders, as well as to promote the growth of good bacteria.

3. Is there a difference between acidophilus and probiotics?

The main difference between acidophilus and Probiotic is that acidophilus is a type of probiotics that lives in the elementary tract of animals whereas probiotic is a good bacterium that protects the body against disease-causing bacteria.

4. Who should not take acidophilus?

Do not take acidophilus without first talking to your doctor if you are pregnant or may become pregnant during treatment. Do not take acidophilus without first talking to your doctor if you are breast-feeding a baby. Do not give any herbal/health supplement to a child without the advice of a doctor.

Editor's Notes

During our natural acidophilus supplement research, we found 24 natural acidophilus supplement products and shortlisted 9 quality products. We collected and analyzed 843,465 customer reviews through our big data system to write the natural acidophilus supplements list. We found that most customers choose natural acidophilus supplements with an average price of $20.87.

The natural acidophilus supplements are available for purchase. We have researched hundreds of brands and picked the top brands of natural acidophilus supplements, including Digestive Advantage, Nature's Bounty, NewRhythm, Nature's Way, OMOGS. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.