Best Softgel Acidophilus Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 6, 2025

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Softgel acidophilus supplements are a popular way to promote digestive health. These supplements contain live cultures of the beneficial bacteria Lactobacillus acidophilus, which can help maintain a healthy balance of gut flora. Softgel acidophilus supplements are easy to swallow and offer a convenient way to support digestive health on the go. They are often used to help alleviate digestive issues such as bloating, gas, and diarrhea. Additionally, some people use acidophilus supplements to support immune system function and overall well-being.

At a Glance: Our Top Picks

Nature's Way Probiotic Pearls Acidophilus for Digestive Health Cover #TOP 1
Nature's Way Probiotic Pearls Acidophilus for Digestive Health
ftb score rating icon 9.9
Nature's Way Probiotic Pearls Womens Cover #TOP 2
Nature's Way Probiotic Pearls Womens
ftb score rating icon 9.8
Nature’s Way Probiotic Pearls Complete Cover #TOP 3
Nature’s Way Probiotic Pearls Complete
ftb score rating icon 9.6

Top 5 Softgel Acidophilus Supplements

Nature's Way Probiotic Pearls Acidophilus for Digestive Health

Nature's Way
04299
Nature's Way Probiotic Pearls Acidophilus for Digestive Health Cover
Nature's Way Acidophilus Probiotic Pearls, Supports Digestive Balance and Gut Health*, Protects Against Occasional Constipation and Bloating*, 1 Billion Live Cultures, 90 Softgels (Packaging May Vary)

Nature's Way Probiotic Pearls Acidophilus is a daily probiotic formula that contains 2 strains and 1 billion cultures in a convenient, once-daily softgel. It helps protect against occasional bloating, constipation, and digestive discomfort while promoting digestive balance, immune, and colon health. The small probiotic pearls are easy to swallow and perfect for taking anywhere and everywhere, with no refrigeration required.

What We Like
Contains 2 strains and 1 billion cultures to promote digestive balance and colon health
Protects against occasional bloating, constipation, and digestive discomfort
Small and easy to swallow, with no refrigeration required
Made with wholesome ingredients and contains no artificial colors
Trusted health partner for digestive support
#TOP 2

Nature's Way Probiotic Pearls Womens

Nature's Way
04213
Nature's Way Probiotic Pearls Womens Cover
Nature's Way Women's Probiotic Pearls, Supports Vaginal and Digestive Health*, 1 Billion Live Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)

Nature's Way Probiotic Pearls are a daily probiotic for women that help support vaginal flora and urinary tract health. With 1 billion live probiotic cultures, these pearls help maintain vaginal and urinary tract health, promote digestive balance, and boost immune health. The active Lactobacilli cultures in the pearls are coated with a triple-layer coating, ensuring their survival to reach your small intestine, where they are most effective. The small size of these pearls makes them easy to swallow and convenient to take anywhere without the need for refrigeration. Made without gluten, yeast-derived ingredients, wheat, salt, dairy, or artificial colors, Nature's Way Probiotic Pearls are a natural and convenient way for women to support their overall well-being.

What We Like
Supports vaginal and urinary tract health
Promotes digestive balance
Boosts immune health
#TOP 3

Nature’s Way Probiotic Pearls Complete

Nature's Way
04369
Nature’s Way Probiotic Pearls Complete Cover
Nature's Way Complete Probiotic Pearls, Supports Digestive Balance*, 1 Billion Live Cultures, Supplement for Men and Women, No Refrigeration Required, 90 softgels (Packaging May Vary)

Nature’s Way Probiotic Pearls is a probiotic supplement that contains six probiotic strains to support digestive balance, regularity, colon health, and protect against occasional bloating, constipation, and digestive discomfort. It provides 2 strains of Lactobacilli for the small intestine and 4 strains of Bifidobacteria for the large intestine to promote digestive balance and colon health, and support immune health. The softgels are easy to swallow and conveniently sized to take anywhere and everywhere, with no refrigeration required. Nature's Way Probiotic Pearls are made with wholesome ingredients and contain no salt, wheat, or artificial colors. Adults can take 1 softgel daily to support their digestive and immune health.

What We Like
Convenient size and no refrigeration required
Contains 6 probiotic strains
Promotes digestive balance and colon health
#TOP 4

Nature's Way Probiotic Pearls for Men and Women 50+

Nature's Way
10510
Nature's Way Probiotic Pearls for Men and Women 50+ Cover
Nature's Way Adults 50+ Probiotic Pearls, Supports Regularity, Immune and Colon Health*, 1 Billion Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)

Nature's Way Probiotic Pearls is a daily supplement designed for adults aged 50+ to support digestive balance, colon health, and immune health. It contains 1 billion live probiotic cultures per serving and 4 strains of Bifidobacteria. The triple-layer softgel protects probiotics from heat, air, and stomach acid to maximize survivability, helping to protect against bloating, constipation, and digestive discomfort. The product does not require refrigeration.

What We Like
Contains 1 billion live probiotic cultures per serving and 4 strains of Bifidobacteria.
Triple-layer softgel protects probiotics from heat, air, and stomach acid to maximize survivability.
Supports digestive balance, colon health, and immune health.
#TOP 5

Nature's Way Probiotic Pearls Elite

Nature's Way
56435
Nature's Way Probiotic Pearls Elite Cover
Nature's Way Elite Extra Strength Probiotic Pearls for Men and Women, Supports Digestive, Immune, Colon Health*, 5 Billion Live Cultures, No Refrigeration Required, 30 Softgels (Packaging May Vary)

Nature's Way Probiotic Pearls Elite is a reliable acidophilus supplement that delivers 5 billion probiotics to support digestive, immune, and colon health. It protects against occasional bloating, constipation, and digestive discomfort with its advanced triple-layer coating that protects each pearl from heat, air, moisture, and stomach acid. Nature's Way Probiotic Pearls Elite is an extra strength formula that offers 5x the potency of Probiotic Pearls Acidophilus. It does not require refrigeration.

What We Like
Delivers 5 billion probiotics to support digestive, immune, and colon health.
Protects against occasional bloating, constipation, and digestive discomfort.
Advanced triple-layer coating protects each pearl from heat, air, moisture, and stomach acid.
Extra strength formula offers 5x the potency of Probiotic Pearls Acidophilus.
Does not require refrigeration.
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is acidophilus supplement used for?

People commonly take acidophilus to treat a type of vaginal inflammation (bacterial vaginosis) and digestive disorders, as well as to promote the growth of good bacteria.

2. Is acidophilus good to take daily?

Lactobacillus acidophilus is generally considered safe for most people. Gas, upset stomach, and diarrhea are potential side effects in some people (not on antibiotic therapy) who take more than 1 to 2 billion L. acidophilus CFUs daily.

3. What is the difference between probiotics and acidophilus?

The main difference between acidophilus and Probiotic is that acidophilus is a type of probiotics that lives in the elementary tract of animals whereas probiotic is a good bacterium that protects the body against disease-causing bacteria.

4. How often should you take acidophilus pills?

For oral dosage form (capsules): For healthy stomach and intestines. Adults—1 capsule once a day. Children—Use and dose must be determined by your doctor.

Editor's Notes

During our softgel acidophilus supplement research, we found 24 softgel acidophilus supplement products and shortlisted 5 quality products. We collected and analyzed 289,491 customer reviews through our big data system to write the softgel acidophilus supplements list. We found that most customers choose softgel acidophilus supplements with an average price of $12.88.

The softgel acidophilus supplements are available for purchase. We have researched hundreds of brands and picked the top brands of softgel acidophilus supplements, including Nature's Way and more. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.