Best Capsules 5-HTP Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2025

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Capsules 5-HTP supplements are a natural way to boost serotonin levels in the body. Serotonin is a neurotransmitter that regulates mood, appetite, and sleep. This supplement is derived from the seeds of an African plant known as Griffonia simplicifolia. Capsules 5-HTP supplements are believed to help alleviate symptoms of depression, anxiety, and insomnia. They are also used for weight loss and to reduce the frequency of migraines. This supplement is easy to take and is generally well-tolerated, but it is important to follow dosage instructions carefully.

At a Glance: Our Top Picks

NUTRAHARMONY 5HTP 400 mg Capsules Cover #TOP 1
NUTRAHARMONY 5HTP 400 mg Capsules
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Horbaach 5HTP 200mg Capsules Cover #TOP 2
Horbaach 5HTP 200mg Capsules
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Organic 5-HTP Capsules with Vitamin B6 & Lions Mane Cover #TOP 3
Organic 5-HTP Capsules with Vitamin B6 & Lions Mane
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Top 10 Capsules 5-HTP Supplements

#TOP 1

NUTRAHARMONY 5HTP 400 mg Capsules

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5HTP 400 mg Capsules - 5-HTP Supplement Tryptophan - Ashwagandha | L-Theanine | St. John's Wort | Vitamins B6 & D3 | 5 HTP - Sleep, Mood & Brain Support - NON-Habit Forming & Drug-Free - 60 Capsules

NUTRAHARMONY 5HTP Capsules offer a powerful blend designed to enhance your mood and support restful sleep. With 400mg of 5-HTP, this supplement helps you maintain a positive outlook and balance in your daily life. The unique formula also includes Ashwagandha and L-Theanine, which promote relaxation and cognitive function. Additionally, Vitamins B6 and D3 in the mix contribute to overall brain health. Made in the USA with high-quality, globally sourced ingredients, you can trust that each capsule is crafted for your well-being.

What We Like
Supports mood enhancement
Promotes restful sleep
Boosts cognitive function
High-quality, USA-made

Horbaach 5HTP 200mg Capsules

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Horbaach 5HTP 200mg Capsules Cover
Horbäach 5HTP 200mg Capsules | 180 Count | Griffonia Simplicifolia | 5HTP Extra Strength Supplement | Non-GMO, Gluten Free | 5 Hydroxytryptophan

Horbaach 5HTP Capsules is a high-strength supplement that provides maximum support for your well-being. Each serving delivers 200mg of 5-HTP, a nutrient produced in the body from L-Tryptophan. With quick-release capsules made from seed extract, this professionally crafted supplement ensures purity and potency. Horbaach, a trusted brand, guarantees laboratory tested, superior quality ingredients. The 5HTP Capsules are naturally free of gluten, wheat, yeast, milk, lactose, soy, artificial color, and flavor, making it suitable for those with dietary restrictions. Improve your overall health and experience the benefits of 5-HTP with Horbaach 5HTP Capsules.

What We Like
Extra strength
Quick-release capsules
Trusted brand

Organic 5-HTP Capsules with Vitamin B6 & Lions Mane

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Organic 5-HTP Capsules with Vitamin B6 & Lions Mane Cover
Organic 5-HTP - 200 mg | 99% 5HTP Concentration, Plus Cofactor Vitamin B6 & Lion’s Mane | Water Extracted from Organic Griffonia Seeds | Supports Mood, Cognition & Sleep (60 Capsules | 30 Servings)

Triquetra Health’s Organic 5-HTP Capsules are a natural solution to promote a calm and relaxed mood, better quality sleep, and mental cognition. Derived from organic Griffonia Seeds and extracted using the purest water extraction method, this 5-HTP supplement has a 99% purity and concentration of 5-HTP, making it 10 times more potent than other leading 5-HTP products on Amazon. The formula is enhanced with vitamin B6 and organic Lions Mane, aiding in the 5-HTP to serotonin conversion process and cognition enhancement properties, respectively. Each serving of 2 capsules provides 200 mg of 5-HTP and 10 mg of Vitamin B6, clinically validated for effectiveness.

What We Like
99% purity and concentration of 5-HTP
Enhanced with vitamin B6 and organic Lions Mane
Natural solution to promote mood, sleep, and cognition
Certified organic and vegan
Clinically validated dosage of 200 mg per serving

NOW Supplements 5-HTP 100mg Veg Capsules

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NOW Supplements 5-HTP 100mg Veg Capsules Cover
NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 120 Veg Capsules

Improve your mood and relaxation with the NOW Supplements 5-HTP 100mg Veg Capsules, which are vegan and support the production of serotonin in the brain and central nervous system. These capsules can impact sleep, mood, appetite, and body temperature. The Griffonia Simplicifolia extract in these capsules helps to extract the intermediate metabolite between the amino acid L-tryptophan and serotonin. The product is GMP Quality Assured, non-GMO, and packaged in the USA by a family-owned company since 1968.

What We Like
Vegan capsules
Supports positive mood and relaxation
GMP Quality Assured
Non-GMO
Family owned and operated company since 1968
#TOP 5

Nutricost 5-HTP 100mg, 240 Capsules

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Nutricost 5-HTP 100mg, 240 Vegetarian Capsules (5-Hydroxytryptophan) - Non-GMO & Gluten Free

If you're looking for a natural way to relieve stress, Nutricost 5-HTP is a great choice. Each bottle contains 240 vegetarian capsules of high-quality 5-HTP, with 100mg per capsule. This supplement is vegetarian-friendly, non-GMO, and gluten-free, making it suitable for a wide range of diets. It's also third-party tested by ISO-accredited laboratories and made in a GMP compliant, FDA registered facility. With Nutricost 5-HTP, you can enjoy the benefits of stress relief in a convenient capsule form.

What We Like
240 capsules per bottle
100mg of 5-HTP per capsule
Vegetarian-friendly, non-GMO, and gluten-free
#TOP 6

DR EMIL NUTRITION 200 MG 5-HTP Plus Formula

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DR. EMIL NUTRITION 200 MG 5-HTP Plus with SAM-e to Maintain Normal Healthy Sleep and Create a Sense of Wellbeing - 5HTP Supplement with Vitamin B6-60 Vegan Capsules, 30 Servings

The DR EMIL NUTRITION 200 MG 5-HTP Plus Formula is a natural supplement that supports mood, stress, and sleep. This formula contains 200mg of pure 5-HTP supplemented with 20mg of SAMe and 20mg of L Tryptophan to optimize 5-HTP conversion and support stress levels in the body. It also contains vitamin B6 for improved 5-HTP conversion. Vitamin B6 has been shown to aid 5-HTP conversion, and this formula has enough to ensure efficacy. This product is vegan and promotes calm and relaxation, making it a natural way to support a calm and relaxed mood by supporting 5-HTP conversion in the body.

What We Like
Contains pure 5-HTP supplemented with SAMe and L Tryptophan to optimize 5-HTP conversion and support stress levels in the body
Vitamin B6 is included to aid 5-HTP conversion, ensuring efficacy even with slight B6 deficiency
Vegan formula that promotes calm and relaxation, making it a natural way to support a calm and relaxed mood by supporting 5-HTP conversion in the body
#TOP 7

Horbaach 5-HTP 400mg Capsules

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Horbaach 5-HTP 400mg Capsules Cover
Horbäach 5HTP 400mg Capsules | 120 Count | Extra Strength Supplement | Non-GMO, Gluten Free | 5 Hydroxytryptophan

Horbaach 5-HTP 400mg Capsules are a high-strength dietary supplement that supports maximum 5-Hydroxytryptophan levels in the body. The supplement delivers 400mg of 5-HTP per serving from seed extract in quick-release capsules. Horbaach supplements are professionally crafted using advanced sourcing to ensure purity and potency always. The product is free of gluten, wheat, yeast, milk, lactose, soy, artificial color & flavor, and is non-GMO.

What We Like
High-strength 5-HTP supplement
Quick-release capsules for maximum support
Professionally crafted for purity and potency
Free of gluten, wheat, yeast, milk, lactose, soy, artificial color & flavor, and non-GMO
#TOP 8

Deal Supplement 5HTP 200mg Capsules with L-Theanine, L-Tryptophan, & GABA

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Deal Supplement 5HTP 200mg Capsules with L-Theanine, L-Tryptophan, & GABA Cover
Deal Supplement 5-HTP 200mg Per Serving, 240 Capsules, 98% African Derived Griffonia Seed Extract | 4 in 1 Formula | Plus Active L Theanine, L Tryptophan, & GABA | Relaxation Support Supplement

Deal Supplement offers a 4-in-1 comprehensive 5HTP formula that combines 5HTP plus L-Theanine, L-Tryptophan, & GABA all inside the same product. Derived from top-grade, west African sourced griffonia simplicifolia, the high-purity extract retains 98% griffonia across every batch. Each bottle contains 180 potent capsules that equal 90 total servings. Take this product during the day to promote a positive mood, relaxation, and support for a good night's sleep. The ultimate chill pill made for the craziest of lifestyles. Quality ensured with 3rd party lab testing and non-GMO ingredients, made in the USA without major allergens.

What We Like
4-in-1 formula with 5HTP, L-Theanine, L-Tryptophan, & GABA for comprehensive support
Derived from top-grade, west African sourced griffonia simplicifolia with 98% purity
180 capsules per bottle for 90 total servings
Promotes positive mood, relaxation, and good sleep support
Non-GMO and made in the USA without major allergens
#TOP 9

NOW 5-HTP 100mg

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NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 60 Veg Capsules

NOW 5-HTP is a vegan capsule that supports the production of serotonin in the brain and central nervous system, which can impact sleep, mood, appetite, and body temperature. It is typically used as a sleep supplement and supports positive mood and relaxation. With certifications such as dairy-free, egg-free, kosher, non-GMO, nut-free, soy-free, vegan/vegetarian, and GMP Quality Assured, you can trust the quality of the product. NOW 5-HTP is a great choice for those who want to improve their sleep quality and mood.

What We Like
Vegan capsules
Supports sleep and mood
Certified and quality assured
#TOP 10

Thorne 5-HTP - Serotonin Support for Sleep and Stress - 90 Capsules

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Thorne 5-HTP - Serotonin Support for Sleep and Stress - 90 Capsules Cover
THORNE 5-Hydroxytryptophan (5-HTP) - Serotonin Support for Sleep and Stress Management - 90 Capsules

The Thorne 5-HTP supplement is a great addition to your daily routine. This supplement offers support for restful sleep, nutritional support for stress, helps decrease sugar cravings, and supports a healthy outlook. With Thorne being chosen by champions and trusted by 100+ pro teams, it's no wonder they are the only supplement manufacturer to collaborate with Mayo Clinic on wellness research and content. This supplement also offers hypoallergenic benefits and is perfect for adults looking for a natural solution to support their sleep and stress management.

What We Like
Helps support restful sleep
Nutritional support for stress
Decreases sugar cravings
Supports a healthy outlook
Trusted by 100+ pro teams and chosen by champions
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is 5-HTP capsules used for?

5-HTP dietary supplements help raise serotonin levels in the brain. Since serotonin helps regulate mood and behavior, 5-HTP may have a positive effect on sleep, mood, anxiety, appetite, and pain sensation.

2. Do 5-HTP supplements work?

It found that supplementing with 5-HTP daily for six months prevented or significantly decreased the number of migraine attacks in 71% of participants ( 33 ). In another study in 48 students, 5-HTP produced a 70% decrease in headache frequency, compared to an 11% decrease in the placebo group ( 34 ).

3. Is it OK to take 5-HTP everyday?

There is no specific recommended daily allowance for 5-HTP. Most people will take 50–100 mg per day after starting at a lower dose of 25 mg and increasing the dose weekly. A person should read their supplement label and talk to a doctor before taking any supplement.

4. What are the side effects of taking 5-HTP?

Side Effects. Reported side effects of 5-HTP include: anxiety. shivering. heart problems.Some people have developed eosinophilia-myalgia syndrome (EMS), which causes muscle tenderness and blood abnormalities, though this may be related to a contaminant in the supplement and not the supplement itself.

Editor's Notes

During our capsules 5-htp supplement research, we found 24 capsules 5-htp supplement products and shortlisted 10 quality products. We collected and analyzed 213,945 customer reviews through our big data system to write the capsules 5-htp supplements list. We found that most customers choose capsules 5-htp supplements with an average price of $20.86.

The capsules 5-htp supplements are available for purchase. We have researched hundreds of brands and picked the top brands of capsules 5-htp supplements, including NUTRAHARMONY, Triquetra Health, NOW Foods, Nutricost, DR. EMIL NUTRITION. The seller of top 1 product has received honest feedback from 4,702 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.