Best Gluten-Free 5-HTP Supplements of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2025

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Gluten-free 5-HTP supplements are a great option for individuals who are looking to improve their mood and reduce symptoms of anxiety and depression without consuming gluten. These supplements are made from the natural amino acid 5-HTP, which is a precursor to serotonin, a neurotransmitter that regulates mood and sleep. By increasing serotonin levels in the brain, 5-HTP supplements can help to alleviate symptoms of depression and anxiety. Additionally, these supplements are gluten-free, making them a safe and effective option for individuals with celiac disease or gluten intolerance. Overall, gluten-free 5-HTP supplements are a natural and safe way to support mental health and wellbeing.

At a Glance: Our Top Picks

Nutricost 5-HTP 200mg Capsules Cover #TOP 1
Nutricost 5-HTP 200mg Capsules
ftb score rating icon 9.8
Horbaach 5HTP 200mg Capsules Cover #TOP 2
Horbaach 5HTP 200mg Capsules
ftb score rating icon 9.7
Doctor's Best 5-HTP Cover #TOP 3
Doctor's Best 5-HTP
ftb score rating icon 9.5

Top 10 Gluten-Free 5-HTP Supplements

#TOP 1

Nutricost 5-HTP 200mg Capsules

B0773815NL
Nutricost 5-HTP 200mg Capsules Cover
Nutricost 5-HTP 200mg, 60 Vegetarian Capsules (5-Hydroxytryptophan) - Non-GMO & Gluten Free

Nutricost 5-HTP Capsules provide a convenient way to support your mood and overall well-being. Each capsule contains 200mg of high-quality 5-HTP, making it easy to incorporate into your daily routine. These capsules are vegetarian-friendly, ensuring that you can enjoy them regardless of your dietary preferences. Additionally, they are non-GMO and gluten-free, which means you can take them with confidence, knowing they align with your health goals. The product is also third-party tested by ISO-accredited laboratories, ensuring you receive a reliable supplement of the highest quality.

What We Like
High-quality 5-HTP
Vegetarian-friendly
Non-GMO and gluten-free
Third-party tested

Horbaach 5HTP 200mg Capsules

CL3963
Horbaach 5HTP 200mg Capsules Cover
Horbäach 5HTP 200mg Capsules | 180 Count | Griffonia Simplicifolia | 5HTP Extra Strength Supplement | Non-GMO, Gluten Free | 5 Hydroxytryptophan

Horbaach 5HTP Capsules is a high-strength supplement that provides maximum support for your well-being. Each serving delivers 200mg of 5-HTP, a nutrient produced in the body from L-Tryptophan. With quick-release capsules made from seed extract, this professionally crafted supplement ensures purity and potency. Horbaach, a trusted brand, guarantees laboratory tested, superior quality ingredients. The 5HTP Capsules are naturally free of gluten, wheat, yeast, milk, lactose, soy, artificial color, and flavor, making it suitable for those with dietary restrictions. Improve your overall health and experience the benefits of 5-HTP with Horbaach 5HTP Capsules.

What We Like
Extra strength
Quick-release capsules
Trusted brand
#TOP 3

Doctor's Best 5-HTP

DRB-00312
Doctor's Best 5-HTP Cover
Doctor's BEST 5-HTP, Supports Mental & Emotional Well-Being, Non-GMO, Vegan, Gluten Free, Soy Free, 100 Mg, 180 Veggie Caps

Doctor's Best Mood Support is a 5-HTP (5-Hydroxy L-Tryptophan) supplement that promotes mood support, calm, and relaxation. It contains 5-HTP, which is extracted from the seeds of the Griffonia simplicifolia plant. 5-HTP is converted into serotonin in the brain, a neurotransmitter that plays a crucial role in regulating sleep, mood, and stress. By aiding serotonin production, this supplement supports mental and emotional well-being, promotes healthy sleep, and helps control appetite. With its drug-free formula, Doctor's Best Mood Support provides a natural way to enhance mood, promote relaxation, and improve sleep quality.

What We Like
Natural mood support
Promotes relaxation and better sleep
Helps control appetite
#TOP 4

Amazing Formulas 5-HTP Supplement

1 Count (Pack of 1)
Amazing Formulas 5-HTP Supplement Cover
Amazing Formulas 5-HTP (Hydroxytryptophan) Supplement | 100 Mg Per Serving | Veggie Capsules | Non-GMO | Gluten Free | Made in USA (1 Pack, 120 Count)

Amazing 5-HTP Capsules by Amazing Nutrition offer 100 mg of 5-HTP Hydroxytryptophan per serving in each of the 120 veggie capsules. These Non-GMO and Gluten-Free capsules are Third Party Tested, ensuring quality. Manufactured in the USA according to GMP Standards, they guarantee Purity & Potency. The 5-HTP supplement may promote a sense of well-being, aid in mood regulation, support better sleep, and improve overall mental health.

What We Like
Potent 5-HTP Content
Non-GMO & Gluten-Free
Third Party Tested
#TOP 5

Piping Rock 5HTP 200mg Capsules

Piping Rock
5781
Piping Rock 5HTP 200mg Capsules Cover
Piping Rock 5HTP 200mg Capsules | 90 Count | Hydroxytryptophan | Non-GMO, Gluten Free Supplement

Piping Rock 5HTP Capsules is a high-quality supplement that delivers 200 mg of 5-Hydroxytryptophan (5-HTP) per serving. 5-HTP is a nutrient that is naturally produced in the body from L-Tryptophan. This supplement is made from a seed extract and comes in quick-release capsules for easy consumption. Piping Rock is devoted to purity, potency, and safety, ensuring that their products are non-GMO and gluten-free. The capsules are laboratory tested using trusted ingredients, providing you with a reliable and effective 5-HTP supplement. With Piping Rock 5HTP Capsules, you can support your overall well-being and enjoy the convenience of a high-quality supplement.

What We Like
High-quality
Quick-release capsules
Non-GMO and gluten-free
#TOP 6

NOW Supplements 5-HTP 100mg Veg Capsules

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Beige
NOW Supplements 5-HTP 100mg Veg Capsules Cover
NOW Foods Supplements, 5-HTP (5-hydroxytryptophan) 100 mg, Neurotransmitter Support*, 120 Veg Capsules

Improve your mood and relaxation with the NOW Supplements 5-HTP 100mg Veg Capsules, which are vegan and support the production of serotonin in the brain and central nervous system. These capsules can impact sleep, mood, appetite, and body temperature. The Griffonia Simplicifolia extract in these capsules helps to extract the intermediate metabolite between the amino acid L-tryptophan and serotonin. The product is GMP Quality Assured, non-GMO, and packaged in the USA by a family-owned company since 1968.

What We Like
Vegan capsules
Supports positive mood and relaxation
GMP Quality Assured
Non-GMO
Family owned and operated company since 1968
#TOP 7

Horbaach 5-HTP 400mg Capsules

CL5784
Horbaach 5-HTP 400mg Capsules Cover
Horbäach 5HTP 400mg Capsules | 120 Count | Extra Strength Supplement | Non-GMO, Gluten Free | 5 Hydroxytryptophan

Horbaach 5-HTP 400mg Capsules are a high-strength dietary supplement that supports maximum 5-Hydroxytryptophan levels in the body. The supplement delivers 400mg of 5-HTP per serving from seed extract in quick-release capsules. Horbaach supplements are professionally crafted using advanced sourcing to ensure purity and potency always. The product is free of gluten, wheat, yeast, milk, lactose, soy, artificial color & flavor, and is non-GMO.

What We Like
High-strength 5-HTP supplement
Quick-release capsules for maximum support
Professionally crafted for purity and potency
Free of gluten, wheat, yeast, milk, lactose, soy, artificial color & flavor, and non-GMO
#TOP 8

BulkSupplements 5-HTP 50mg Capsules

BulkSupplements 5-HTP 50mg Capsules Cover
BulkSupplements.com 5-HTP Capsules - 5-Hydroxytryptophan, 5-HTP 50mg - 5 HTP Supplement for Well-Being - Amino Acid & Gluten Free, 1 Capsule per Serving, 365 Capsules (Pack of 1)

BulkSupplements 5-HTP Capsules are designed to enhance your overall health and well-being. These capsules provide essential nutrients that can help you feel your best every day. They are convenient for busy lifestyles, allowing you to maintain your wellness routine on the go. You’ll appreciate the transparency of this supplement, as it undergoes rigorous third-party testing to ensure quality. With a commitment to excellence, these capsules are produced in a facility that adheres to strict cGMP standards, ensuring you receive a consistent and reliable product every time.

What We Like
Supports overall health
Convenient for busy lifestyles
Third-party tested for quality
Produced in cGMP compliant facility
#TOP 9

Nutricost 5-HTP Powder

NC5HTPPDR1
Nutricost 5-HTP Powder Cover
Nutricost 5-HTP Powder 25 Grams (300mg Per Serving) - Gluten Free & Non-GMO, Pure 5-htp

Nutricost 5-HTP Powder is a high-quality supplement that contains 25 grams of pure 5-HTP powder per bottle. This powder is gluten-free and non-GMO, making it a safe choice for those with dietary restrictions. With 300mg per serving, each bottle provides 83 servings, ensuring long-lasting use. The included scoop makes it convenient to measure the right amount for each serving. Nutricost 5-HTP Powder is made in a GMP compliant, FDA registered facility, ensuring its quality and safety. This supplement is ideal for individuals looking to support their mood, sleep, and overall well-being.

What We Like
High-quality
Gluten-free & Non-GMO
Long-lasting supply
#TOP 10

Nature's Nutrition 5-HTP Supplement Capsules

NN5HTPCapsules120
Nature's Nutrition 5-HTP Supplement Capsules Cover
5 HTP Supplement Vegetarian Capsules 200mg 5HTP Plus Calcium for Brain Support - Extra Strength Griffonia Simplicifolia 5-HTP Formula - 5 Hydroxytryptophan - Gluten Free & Non-GMO - 120 Capsules

Feel relaxed and support your mood with Nature's Nutrition 5-HTP Supplement Capsules. Made from natural and Non-GMO Griffonia simplicifolia plants, each serving contains 200mg of 5HTP and 328mg of calcium for optimal support. This supplement is bottled in the USA following strict cGMP guidelines and is third-party certified for purity and quality. Suitable for adults, men, and women, these capsules are perfect for supporting brain health, sleep, and mood. Plus, they are gluten-free and come in a 120-count bottle.

What We Like
Contains 200mg of 5HTP plus 328mg of calcium per serving for optimal support
Non-GMO and made from natural Griffonia simplicifolia plants
Bottled in the USA following strict cGMP guidelines and third-party certified for purity and quality
Suitable for adults, men, and women to support brain health, sleep, and mood
Gluten-free and comes in a 120-count bottle
Buying Guide Image

Frequently Asked Questions (FAQs)

1. Who should not take 5-HTP?

People with high blood pressure or diabetes should talk to their doctor before taking 5-HTP. If you take antidepressants, you should not take 5-HTP (see "Possible Interactions" section). People with liver disease, pregnant women, and women who are breastfeeding should not take 5-HTP.

2. Is Natrol 5-HTP gluten free?

Natrol 5-HTP TR is 100% vegetarian and has a controlled delivery system that releases 5-HTP slowly and then steadily over a period of 15 hours. No yeast, wheat, corn, milk, egg, soy, glutens, artificial colors or flavors, added sugar, starch or preservatives.

3. When should you not take 5-HTP?

Do not take 5-HTP if you're taking other medications that increase serotonin levels, such as antidepressants like SSRIs and MAO inhibitors. Use caution when taking carbidopa, a medication for Parkinson's disease. 5-HTP is not recommended for people with Down syndrome, as it has been linked to seizures.

Editor's Notes

During our gluten-free 5-htp supplement research, we found 24 gluten-free 5-htp supplement products and shortlisted 10 quality products. We collected and analyzed 106,737 customer reviews through our big data system to write the gluten-free 5-htp supplements list. We found that most customers choose gluten-free 5-htp supplements with an average price of $17.17.

The gluten-free 5-htp supplements are available for purchase. We have researched hundreds of brands and picked the top brands of gluten-free 5-htp supplements, including Nutricost, Doctor's BEST, Amazing Nutrition, Piping Rock, NOW Foods. The seller of top 1 product has received honest feedback from 30,754 consumers with an average rating of 4.9.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.