Best 5-HTP Supplement Tablets of 2025

Elisa Drew Avatar
Elisa Drew
Last Updated: Jan 10, 2025

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5-HTP supplement tablets are a natural way to boost serotonin levels in the brain, which can improve mood, reduce anxiety, and enhance sleep. Made from the seeds of the Griffonia simplicifolia plant, these supplements are a popular alternative to prescription antidepressants. They are also believed to aid in weight loss by reducing cravings and suppressing appetite. 5-HTP supplement tablets are easy to take, and can be found in most health food stores and online retailers. As with any supplement, it is important to consult with a healthcare professional before adding 5-HTP to your daily routine.

At a Glance: Our Top Picks

Nature Made Chewable 5HTP 100mg Cover #TOP 1
Nature Made Chewable 5HTP 100mg
ftb score rating icon 9.9
Natrol 5-HTP Time Release Tablets Cover #TOP 2
Natrol 5-HTP Time Release Tablets
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Natrol 5-HTP Time Release Tablets Cover #TOP 3
Natrol 5-HTP Time Release Tablets
ftb score rating icon 9.6

Top 8 5-HTP Supplement Tablets

#TOP 1

Nature Made Chewable 5HTP 100mg

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Nature Made Chewable 5HTP 100mg Cover
Nature Made Chewable 5HTP 100mg, 5-HTP Mood Support Supplement, 30 5 HTP Chewable Tablets, 30 Day Supply

Nature Made 5HTP Chewables are a mood support supplement that contains 30 chewable tablets, providing a 30-day supply. These delicious orange citrus flavored tablets are vegetarian, gluten-free, and free from artificial flavors, synthetic dyes, and dairy. The 5 HTP in these chewables is an amino acid that helps in the production of serotonin, supporting a positive mood. With just one tablet per day, you can conveniently improve your mood and overall well-being. Nature Made is the #1 Pharmacist Recommended Vitamin & Supplement Brand*, and these chewables are made in the USA with quality global ingredients. Please note that this product is not intended to diagnose, treat, cure, or prevent any disease.

What We Like
Mood support
Delicious orange citrus flavor
Vegetarian and gluten-free
#TOP 2

Natrol 5-HTP Time Release Tablets

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Natrol 5-HTP Time Release Tablets Cover
Natrol 5-HTP 100mg, Dietary Supplement Helps Support a Balanced Mood, 90 Time Release Tablets, 22-45 Day Supply

Natrol 5-HTP Time Release Tablets are a drug-free way to promote a calm and relaxed mood throughout the day. With a clean ingredient list, including 5-Hydroxytryptophan, these vegetarian tablets are non-GMO, gluten-free, and free of artificial flavors, sweeteners, and preservatives. The time-release formulation provides a gradual release of 5-HTP, helping to maintain a positive outlook and reduce stress. Natrol is dedicated to creating innovative, quality products to help you maintain good health and thrive in your busy modern lifestyle.

What We Like
Drug-free way to promote a calm and relaxed mood
Clean ingredient list, non-GMO, gluten-free, and vegetarian
Time-release formulation provides a gradual release of 5-HTP throughout the day
#TOP 3

Natrol 5-HTP Time Release Tablets

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Natrol 5-HTP Time Release Tablets Cover
Natrol Mood + Stress 5-HTP 200mg Time Release Tablets, 30 Count, 30 Day Supply

Looking for a drug-free way to promote a calm and relaxed mood? Look no further than Natrol 5-HTP Time Release Tablets. These clean, vegetarian tablets slowly release 5-HTP throughout the day to help maintain a positive outlook and promote a calm, relaxed mood. As the #1 5-HTP brand in America, Natrol is a trusted manufacturer of vitamins and supplements.

What We Like
Drug-free way to promote a calm and relaxed mood
Clean, vegetarian tablets
Slowly releases 5-HTP throughout the day
Helps maintain a positive outlook
#1 5-HTP brand in America
#TOP 4

Natrol 5-HTP Fast Dissolve Tablets

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Natrol 5-HTP Fast Dissolve Tablets Cover
Natrol 5-HTP 100mg, Drug-Free Dietary Supplement Helps Support Balanced Mood, 30 Mixed Berry-Flavored Fast Dissolve Tablets, 15-30 Day Supply

Natrol 5-HTP Fast Dissolve Tablets is a drug-free supplement that promotes a calm and relaxed mood. It is non-GMO, gluten-free, and vegetarian, with clean ingredients free of artificial flavors, sweeteners, and preservatives. The unique fast dissolve form enables faster absorption and can be taken anytime, anywhere. Natrol is the #1 5-HTP brand in America and one of the nation's leading manufacturers of vitamins and supplements.

What We Like
Promotes a calm and relaxed mood
100% drug-free, non-GMO, gluten-free, and vegetarian
Fast dissolve form enables faster absorption and can be taken anytime, anywhere

Superior Source 5-HTP Supplements

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Superior Source 5-HTP Supplements Cover
Superior Source 5-HTP (5-hydroxytryptophan) 50 mg, Quick Dissolve MicroLingual Tablets, 60 Ct, Neurotransmitter Support, Supports Restful Sleep, Non-GMO

Superior Source 5-HTP Supplements are a great way to support positive mood and promote restful sleep. These quick-dissolving tablets contain 5-HTP, which is the primary precursor to serotonin production in the body. By promoting relaxed mood and restful sleep, these supplements can help you feel more balanced and rejuvenated. Unlike hard tablets that take time to break down, these micro tablets melt instantly under the tongue for maximum absorption. They are also non-GMO, gluten-free, preservative-free, and sugar-free, making them a pure and natural choice. With Superior Source, you can trust that you're getting a high-quality product that is tested for potency, contaminants, and purity. Take control of your well-being with Superior Source 5-HTP Supplements.

What We Like
Supports positive mood
Promotes restful sleep
Quick dissolving tablets
#TOP 6

Nature's Way 5-HTP 60 Count

Nature's Way
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Nature's Way 5-HTP 60 Count Cover
Nature's Way 5-HTP, Calms Nerves and Supports Appetite*, L-5-Hydroxytryptophan, Vitamins B6 & C, Griffonia Bean Extract 50 mg Per Tablet, 60 Count

Nature's Way 5-HTP 60 Count is a supplement that supports your mood and appetite. As a precursor to serotonin, it helps in calming your nerves. With L-5-Hydroxytryptophan, Vitamin B6, and Vitamin C, it provides a comprehensive solution. Each tablet contains 50 mg of 5-HTP from Griffonia bean extract. The tablets are enteric coated for better absorption. Being gluten-free and vegetarian, they cater to various dietary needs, containing no sugar, salt, yeast, wheat, soy, dairy products, artificial colors, flavors, or preservatives.

What We Like
Precursor to serotonin
Mood and appetite support
Enteric coated for absorption
#TOP 7

Natrol 5-HTP Mood Positive Tablets

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Natrol 5-HTP Mood Positive Tablets Cover
Natrol Mood Positive 5-HTP 50mg With L-Theanine, Vitamin B6, Vitamin B12 and Folate, Dietary Supplement Helps Support a Positive Mood, 50 Tablets, 25-50 Day Supply

Natrol 5-HTP Mood Positive Tablets are a natural and drug-free way to promote a calm and relaxed mood by enabling the body's synthesis of serotonin. The supplement can help improve sleep, control appetite, and promote a positive outlook. Natrol 5-HTP is a non-habit forming supplement that is safe to use for adults. The 50mg formula is perfect for those starting to use a 5-HTP supplement for stress, so they can find the right dose perfect for their individual needs.

What We Like
Helps promote relaxation and calmness
May improve sleep quality
Can help control appetite
Non-habit forming and safe to use
Contains natural ingredients that promote a positive outlook
#TOP 8

Superior Source 5-HTP Supplements (60 Tablets)

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Superior Source 5-HTP Supplements (60 Tablets) Cover
Superior Source 5-HTP 75mg. (60 Tablets)

Superior Source 5-HTP Supplements support your nervous system and help maintain brain health, while being essential for normal sleep patterns. These supplements can be a great addition to your daily routine, providing various benefits to your overall health.

What We Like
Supports nervous system
Essential for normal sleep patterns
Maintains brain health
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is 5-HTP tablets good for?

5-HTP tablets have several potential benefits, including treating mild-to-moderate depression, fibromyalgia, insomnia, migraines and other headaches, and obesity. However, further research is needed to fully understand and confirm these effects.

2. Is it OK to take 5-HTP everyday?

Taking 5-HTP in doses of up to 400 mg daily for up to one year is generally considered safe. However, there are potential side effects, such as heartburn, stomach pain, nausea, vomiting, diarrhea, drowsiness, sexual problems, and muscle problems. It is important to consult with a healthcare professional before starting any new supplement regimen.

3. Is there a downside to taking 5-HTP?

While 5-HTP is generally well-tolerated, common side effects may include gastrointestinal symptoms like stomach pain, heartburn, nausea, vomiting, and diarrhea. Less commonly, it can cause headache, insomnia, muscle problems, sexual difficulties, and a rapid or irregular heartbeat. If you experience any concerning side effects, it is recommended to discontinue use and consult with a healthcare professional.

4. Does 5-HTP work immediately?

When taken as a sleep aid, 5-HTP may start working immediately. The increased amount of 5-HTP signals the body to synthesize serotonin, which can have a relaxing effect and promote better sleep. However, individual responses may vary, and it is important to follow the recommended dosage and consult with a healthcare professional.

5. Why does 5-HTP make me happy?

5-HTP is a natural chemical and precursor to serotonin, a neurotransmitter responsible for producing "feel-good" chemicals in the brain and body. By increasing serotonin levels, 5-HTP may contribute to feelings of happiness and well-being. However, it is important to note that individual responses may vary, and it is recommended to consult with a healthcare professional for personalized advice.

6. Should I take 5-HTP in the morning or at night?

To support relaxation and maintain a healthy sleep cycle, it is generally recommended to take 5-HTP before bed as part of a bedtime routine. However, it is best to follow the specific instructions and recommendations provided by the manufacturer or consult with a healthcare professional for personalized advice.

7. Can 5-HTP cause weight gain?

5-HTP has been shown to potentially reduce appetite and promote weight loss. It does this by stimulating serotonin production in the brain. While more research is needed to fully understand its effects on weight, some studies suggest that 5-HTP may be beneficial for weight management. It is important to note that individual responses may vary, and it is recommended to consult with a healthcare professional for personalized advice.

Editor's Notes

During our 5-htp supplement tablet research, we found 24 5-htp supplement tablet products and shortlisted 8 quality products. We collected and analyzed 65,926 customer reviews through our big data system to write the 5-htp supplement tablets list. We found that most customers choose 5-htp supplement tablets with an average price of $19.13.

The 5-htp supplement tablets are available for purchase. We have researched hundreds of brands and picked the top brands of 5-htp supplement tablets, including Nature Made, Natrol, Superior Source, Nature's Way. The seller of top 1 product has received honest feedback from 385 consumers with an average rating of 4.7.

Written by
Elisa Drew Avatar

Elisa Drew is a really professional copywriter specializing in baby products with five years of experience working as a pediatrician once. She has published a series of baby books purchased by over thirty thousand people in the United States.