Best Tablet Laxatives of 2026

Bonnie Salem Avatar
Bonnie Salem
Last Updated: Jan 16, 2026

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Tablet laxatives are a popular choice for those seeking relief from constipation. These tablets are designed to stimulate bowel movements and promote regularity. They come in various forms, including chewable tablets and those that must be swallowed whole. Some tablet laxatives are made with natural ingredients, while others contain synthetic compounds. It is important to read the label and follow the instructions carefully to ensure safe and effective use. While tablet laxatives can provide short-term relief, it is important to address the underlying causes of constipation and make lifestyle changes to promote long-term digestive health.

At a Glance: Our Top Picks

Dulcolax Stimulant Laxative Tablets Cover #TOP 1
Dulcolax Stimulant Laxative Tablets
ftb score rating icon 9.9
Senokot-S Dual Action Natural Vegetable Laxative Tablets, 60 ct Cover #TOP 2
Senokot-S Dual Action Natural Vegetable Laxative Tablets, 60 ct
ftb score rating icon 9.8
Dulcolax Stimulant Laxative Tablets Cover #TOP 3
Dulcolax Stimulant Laxative Tablets
ftb score rating icon 9.6

Top 10 Tablet Laxatives

#TOP 1

Dulcolax Stimulant Laxative Tablets

681421020824
Regular
Dulcolax Stimulant Laxative Tablets Cover
Dulcolax Stimulant Laxative Tablets, Predictable & Effective Constipation Relief, Relieves Straining & Bloating, Bisacodyl 5 mg, 100 Count

Dulcolax Stimulant Laxative Tablets are designed to provide gentle overnight relief from occasional constipation and irregularity. Made with bisacodyl, the active ingredient that stimulates the intestines, this product is doctor-recommended and can provide relief in 6-12 hours. The 100-count box of comfort coated tablets is perfect for those who want a dependable solution to hard, dry stools.

What We Like
Fast constipation relief
Predictable effectiveness
Easy to take
Good value
Recommended by doctors
#TOP 2

Senokot-S Dual Action Natural Vegetable Laxative Tablets, 60 ct

367618310601
White
60 Count
Senokot-S Dual Action Natural Vegetable Laxative Tablets, 60 ct Cover
Senokot-S Dual Action Natural Vegetable Laxative Ingredient Plus Stool Softener Tablets, Docusate Sodium, Senna Concentrate, Gentle, Overnight Relief From Occasional Constipation, 60 ct

Senokot-S Dual Action Tablets provide gentle and effective overnight relief from occasional constipation using a natural vegetable laxative ingredient plus a stool softener. It eases the discomfort of hard and dry stools, and can be used in children ages 2+. Senokot-S uses a standardized senna concentrate for predictable relief.

What We Like
Gentle and effective relief
Eases discomfort associated with hard, dry stools
Can be used in children ages 2
#TOP 3

Dulcolax Stimulant Laxative Tablets

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Dulcolax Stimulant Laxative Tablets Cover
Dulcolax Stimulant Laxative Tablets, Predictable & Effective Constipation Relief, Relieves Straining & Bloating, Bisacodyl 5 mg, 10 Count

Dulcolax Laxative Tablets are designed to provide quick and reliable relief from constipation. With just one tablet, you can start experiencing relief in as little as six to twelve hours, making it ideal for those unexpected moments when you need help. The active ingredient, bisacodyl, works to stimulate your intestines, helping to restore your natural gut rhythm. Whether you're at home or traveling, these comfort-coated tablets are easy to pack for on-the-go relief, ensuring that you can maintain regularity even during stressful times.

What We Like
Effective for colon prep
Quick relief
Convenient small pack
Good price
Timely delivery
#TOP 4

Senokot Regular Strength Senna Laxative Tablets

20367618000049
Senokot Regular Strength Senna Laxative Tablets Cover
Senokot Regular Strength Senna Laxative Tablets Constipation Relief for Adults, 100 count

The Senokot Regular Strength Laxative offers reliable overnight relief from occasional constipation, making it easier for you to wake up feeling comfortable. It uses a natural vegetable ingredient called purified senna, which is gentle on your system but effective in promoting bowel movements. This product is clinically proven, so you can trust it to work safely and efficiently. By taking Senokot at bedtime, you give it time to gently ease your digestive system overnight, helping you avoid discomfort and irregularity. Overall, the Senokot Regular Strength Laxative is a natural and dependable option for managing occasional constipation.

What We Like
Overnight constipation relief
Natural vegetable ingredient
Clinically proven formula
Gentle bowel movement aid
#TOP 5

Senokot Extra Strength Senna Laxative Tablets

10367618120061
Senokot Extra Strength Senna Laxative Tablets Cover
Senokot Extra Strength Senna Laxative Tablets for Constipation Relief for Adults 36 Count

Senokot Extra Strength Laxative offers gentle overnight relief from occasional constipation by encouraging your muscles to move stool naturally. Taking it at bedtime helps you wake up feeling more comfortable and regular without harsh effects. The extra strength formula uses a carefully measured amount of senna, a natural vegetable ingredient, to provide effective support while still being gentle on your system. This product is made with purified senna, ensuring high quality and dependable results for those times when you need a little help with bowel movements. Senokot Extra Strength Laxative is a natural and reliable option for easing constipation gently and effectively.

What We Like
Gentle overnight relief
Extra strength formula
Natural vegetable ingredient
Purified senna quality
Dependable constipation aid
#TOP 6

Prunelax Ciruelax Maximum Relief Natural Laxative

EX1469
Prunelax Ciruelax Maximum Relief Natural Laxative Cover
Prunelax Ciruelax Maximum Relief Laxative Tablets with Natural Senna for Occasional Constipation, Senna Extract, Vegan & Gluten-Free, Gentle Overnight Relief - 100ct

Prunelax Ciruelax Maximum Relief Natural Laxative is a vegan and gluten-free health product made of natural Senna extract, containing 25mg of sennosides B in each tablet, which works in just 8 to 12 hours to provide gentle overnight relief for occasional constipation. You can take 1 to 3 tablets daily, and it is useful for mild constipation caused by poor eating habits, lack of exercise, and inadequate consumption of natural fiber.

What We Like
Vegan and gluten-free health product
Works in just 8 to 12 hours
Provides gentle overnight relief
#TOP 7

GenCare Senna-S Laxative Plus Stool Softener

GenCare Senna-S Laxative Plus Stool Softener Cover
GenCare - Senna-S Natural Vegetable Laxative Plus Stool Softener Dual Action (200 Tablets) Value Pack | Gentle Dependable Overnight Relief of Occasional Constipation Generic for Senokot-S

GenCare Laxative Plus offers natural and effective relief from occasional constipation, bloating, and irregularity. This product works overnight, allowing you to wake up feeling better after taking it before bed. The dual-action formula combines sennosides to stimulate bowel movements and docusate sodium to soften hard stools, making your experience more comfortable. It's easy to use, as the tablets are simple to swallow and eliminate the need for messy liquids or suppositories. Plus, with the 200-tablet value pack, you can save money while ensuring that you always have gentle relief on hand for your family.

What We Like
Natural and effective relief
Dual-action formula
Easy to swallow tablets
Cost-effective value pack
#TOP 8

Senna Laxative 600 Tablets by GenCare

EB-001
Senna Laxative 600 Tablets by GenCare Cover
GenCare Senna Laxative 600 Tablets Senna 8.6mg Tablets with Natural Sennosides | Laxatives for Constipation, Bloating, Gas & Irregularity Relief. Safe & Effective | Generic for Senokot

GenCare Senna Laxative is an all-natural vegetable-based laxative that comes in a 600 tablet bulk savings bottle to keep you and your family prepared. It helps relieve constipation, bloating, gas, and irregularity safely and effectively. The tablets, made from the Senna medicinal plant, are easy to swallow and provide natural relief, eliminating the need for harsh chemicals or colon cleanse concoctions. They also help reduce bloating and gas by naturally stimulating the movement of your colon and intestines. For best results, take the tablets as directed in the evening before bedtime, and wake up with less discomfort and more regularity. The product comes with a 100% satisfaction guarantee.

What We Like
Contains all-natural vegetable-based sennosides
Provides relief from constipation, bloating, gas, and irregularity
Reduces bloating and gas by stimulating colon and intestine movement
#TOP 9

Puregen Labs Senna-S Dual Action Laxative 250 Tablets

Puregen Labs Senna-S Dual Action Laxative 250 Tablets Cover
Puregen Labs Senna-S Natural Vegetable Laxative Plus Stool Softener Dual Action - 250 Tablets Senna Plus | Gentle Dependable Overnight Relief of Occasional Constipation

The Puregen Senna-S Laxative offers a dual-action formula designed to ease occasional constipation. It combines two natural ingredients: sennosides from the Senna plant, which gently stimulate your bowel to encourage regular movement, and docusate, a stool softener that adds moisture to your stool, making it easier to pass. This combination helps not only relieve constipation but also reduces uncomfortable gas and bloating by promoting natural colon activity. You can expect results within 6 to 12 hours, making it a reliable option for overnight relief when taken as directed before bedtime.

What We Like
Dual-action formula
Natural vegetable laxative
Effective stool softener
Relieves gas and bloating
Fast overnight relief
#TOP 10

GenCare Maximum Strength Senna Laxative

GenCare Maximum Strength Senna Laxative Cover
GenCare - Maximum Strength Senna Laxative 25mg (100 Tablets) - Gentle Constipation Relief Sennosides USP Stimulant Laxatives Digestion Pills - Natural Overnight Relief while You Sleep - Generic Ex Lax

GenCare Senna Laxative offers powerful relief from constipation with its easy-to-swallow tablets. Each tablet contains 25mg of Sennosides, a natural stimulant that helps encourage bowel movements overnight. You can take the tablets before bed, making it convenient for those who want to wake up feeling better. With a satisfaction guarantee, you can trust that this product is designed for your comfort and effectiveness. Plus, the bulk savings bottle ensures you have a reliable supply on hand when you need it.

What We Like
Gentle overnight relief
Easy-to-swallow tablets
Natural stimulant laxative
100% satisfaction guarantee
Buying Guide Image

Frequently Asked Questions (FAQs)

1. What is the best laxative tablet?

Stimulant laxatives such as Senokot (made from senna pods) and Dulcolax (active ingredient: bisacodyl) are the fastest-working oral laxatives, with overnight results. They stimulate the muscles lining your gut, helping to move things along.

2. Is there a tablet laxative?

Most are available to buy from over-the-counter or online and without a prescription. Laxatives can be taken orally (by mouth) in the form of liquids, tablets, or capsules. They can also be taken through the rectum – for example, suppositories or enemas.

3. What is laxative tablets used for?

This medication is used to treat constipation. It increases the bulk in your stool, an effect that helps to cause movement of the intestines. It also works by increasing the amount of water in the stool, making the stool softer and easier to pass.

4. How fast does a pill laxative work?

It may take 6 to 12 hours before this medication causes a bowel movement. Tell your doctor if your condition persists or worsens, or if bleeding from the rectum occurs. If you think you may have a serious medical problem, seek immediate medical attention.

Editor's Notes

During our tablet laxative research, we found 24 tablet laxative products and shortlisted 10 quality products. We collected and analyzed 246,186 customer reviews through our big data system to write the tablet laxatives list. We found that most customers choose tablet laxatives with an average price of $15.90.

The tablet laxatives are available for purchase. We have researched hundreds of brands and picked the top brands of tablet laxatives, including Dulcolax, Senokot, Prunelax, GenCare, P Puregen Labs. The seller of top 1 product has received honest feedback from 384 consumers with an average rating of 4.7.

Written by
Bonnie Salem Avatar

Bonnie Salem is a stay-at-home mother with two-year-old twins and has spent almost half of her life surrounded by baby products. As a mother and a professional copywriter, she has an insightful and unique eye for researching products suitable for infants. Bonnie Salem is an expert in health and nutrition who lives with her family in New Jersey. She has over 15 years of working experience in an institute of medicine after graduating from the University of Toronto. She is highly interested in personal health and wellness.